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Breast Cancer Therapy: Defined Host–Guest Chemistry on Nanocarbon for Sustained Inhibition of Cancer (Small 42/2016)

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Small 2016年第42期12卷

作者： Fatemeh Ostadhossein Santosh K. Misra Prabuddha Mukherjee Alireza Ostadhossein Enrique Daza Saumya Tiwari Shachi Mittal Mark C. Gryka Rohit Bhargava Dipanjan Pan Department of Bioengineering University of Illinois at Urbana-Champaign 1304 W. Springfield Ave. Urbana IL 61801 USA Department of Engineering Science and Mechanics Pennsylvania State University University Park PA 16802 USA Departments of Bioengineering Electrical and Computer Engineering Chemical and Biomolecular Engineering Chemistry and Mechanical Science and Engineering Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign 1304 W. Springfield Ave. Urbana IL 61801 USA Carle Foundation Hospital 502 N. Busey St. Urbana IL 61801 USA Departments of Bioengineering and Materials Science and Engineering Beckman Institute for Advanced Science and Technology Institute for Sustainability in Energy and Environment 502 N. Busey St. Urbana IL 61801 USA

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Pediatric rehabilitation with the reachMAN's modular handle

Pediatric rehabilitation with the reachMAN's modular handle

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Liu Zhu Tong Hian Tat Ong Jia Xuan Tan Jeremy Lin Etienne Burdet S. S. Ge Chee Leong Teol the Department of Mechanical Engineering National University of Singapore Khoo Teck Puat-National University Children's Medical Institute National University Hospital Singapore the Department of Rehabilitation National University Hospital Singapore Department of Bioengineering Imperial College of Science Technology and Medicine London UK Department of Electrical and Computer Engineering National University of Singapore

ISBN: (纸本)9781424492695

This paper presents the results of a preliminary study with one cerebral palsy child using the ReHaptic Handle, a novel robotic device for the pediatric rehabilitation of upper limb function. The device has two degrees-of-freedom to train pinching, forearm supination/pronation and wrist flexion/extension movements. Interactive computer games have been implemented to increase subjects' participation and engagement, thus promoting motor recovery. Pinching, with the index finger and thumb, forearm supination/pronation as well as wrist flexion/extension were trained two or three times a week for 15 minutes each. An increase in forearm supination/pronation movement precision and smoothness was observed with the subject, as well as a reduction in the movement duration.

关键词： Pediatric rehabilitation reachMAN's modular handle index finger pediatric rehabilitation Index Finger Forearm computer Games

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Direct Observation of Plasmonic Enhancement of Emission in Ag-nanoparticle-decorated ZnO nanostructures

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Microscopy and Microanalysis 2015年第S3期21卷 2389-2390页

作者： Jordan Hachtel Daniel Mayo Claire E. Marvinney Anas Mouti Richard Mu Stephen J. Pennycook Andrew R. Lupini Matthew F. Chisholm Richard F. Haglund Sokrates T. Pantelides Vanderbilt University Department of Physics and Astronomy Nashville TN USA Oak Ridge National Laboratory Materials Science and Technology Division Oak Ridge TN USA Vanderbilt University Interdisciplinary Materials Science Program Nashville TN USA Fisk University Department of Physics and Astronomy Nashville TN USA National University of Singapore Department of Materials Science and Engineering Singapore Vanderbilt University Department of Electrical Engineering and Computer Science Nashville TN USA

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Impedance Spectroscopy to Monitor Fracture Healing

Impedance Spectroscopy to Monitor Fracture Healing

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Monica C. Lin Safa T. Herfat Chelsea S. Bahney Meir Marmor Michel M. Maharbiz the Bioengineering Department at the University of California - Berkeley CA 94720 and the University of California - San Francisco CA 94158 USA the Department of Orthopaedic Surgery at the University of California - San Francisco/ San Francisco General Hospital Orthopaedic Trauma Institute San Francisco CA 94110 USA the Electrical Engineering & Computer Science Department and the Bioengineering Department at the University of California - Berkeley CA 94720 USA

ISBN: (纸本)9781424492695

An estimated 7.9 million fracture injuries occur each year in the United States, of which a substantial fraction result in delayed or non-union. Current methods of monitoring fracture healing include taking x-rays and making clinical observations. However, x-ray confirmation of bone healing typically lags behind biologic healing, and physician assessment of healing is fraught with subjectivity. No standardized methods exist to assess the extent of healing that has taken place in a fracture. Without such knowledge, interventions to aid healing and prevent fracture non-union are often delayed, leading to increased morbidity and suffering to patients. We are developing an objective measurement tool that utilizes electrical impedance spectroscopy to distinguish between the various types of tissue present during the different stages of fracture healing. Preliminary measurements of cadaveric tissues reveal adequate spread in impedance measurements and differences in frequency response among different tissue types. Electrodes implanted in a simulated fracture created in an ex vivo cadaver model yield promising results for our system's ability to differentiate between the stages of fracture healing.

关键词： Impedance Spectroscopy Monitor Fracture Healing United States Fracture Healing impedance spectroscopy Wound Healing impedance-spectroscopy measuring tools cracks Bone Fracture X-rays Characteristic impedance

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Active shape-morphing elastomeric colloids in short-pitch cholesteric liquid crystals

arXiv

引用

arXiv 2016年

作者： Evans, Julian S. Sun, Yaoran Senyuk, Bohdan Keller, Patrick Pergamenshchik, Victor M. Lee, Taewoo Smalyukh, Ivan I. Department of Physics University of Colorado BoulderCO80309 United States Centre for Optical and Electromagnetic Research Zhejiang University Hangzhou310058 China Institut Curie Centre de Recherche CNRS UMR 168 Université Pierre et Marie Curie Paris cedex 0575248 France Department of Chemistry and Biochemistry and Liquid Crystal Materials Research Center University of Colorado BoulderCO80309 United States Material Science and Engineering Program Department of Electrical Computer & Energy Engineering Liquid Crystal Materials Research Center University of Colorado BoulderCO80309 United States Institute of Physics Prospect Nauky 46 Kyiv03039 Ukraine Renewable and Sustainable Energy Institute National Renewable Energy Laboratory University of Colorado BoulderCO80309 United States

Active elastomeric liquid crystal particles with initial cylindrical shapes are obtained by means of soft lithography and polymerization in a strong magnetic field. Gold nanocrystals infiltrated into these particles mediate energy transfer from laser light to heat, so that the inherent coupling between the temperature-dependent order and shape allows for dynamic morphing of these particles and well-controlled stable shapes. Continuous changes of particle shapes are followed by their spontaneous realignment and transformations of director structures in the surrounding cholesteric host, as well as locomotion in the case of a nonreciprocal shape morphing. These findings bridge the fields of liquid crystal solids and active colloids, may enable shape-controlled self-assembly of adaptive composites and light-driven micromachines, and can be understood by employing simple symmetry considerations along with electrostatic analogies. Copyright © 2016, The Authors. All rights reserved.

关键词： Colloids

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Polarization controlled output of electrohydrodynamic jet printed quantum dot embedded photonic crystals for display applications

Polarization controlled output of electrohydrodynamic jet pr...

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IEEE Photonics Conference (IPC)

作者： Gloria G. See Lu Xu Erick Sutanto Andrew G. Alleyne Ralph G. Nuzzo Brian T. Cunningham Dep of Electrical and Computer Engineering Micro and Nanotechnology Laboratory IL USA Dept. of Chemistry University of Illinois at Urbana-Champaign Urbana Illinois USA Mechanical Science and Engineering Department University of Illinois at Urbana-Champaign Urbana IL USA Dept. of Bioengineering 1270 Digital Computer Laboratory Urbana IL USA

We demonstrate a replica molded photonic crystal structure with embedded quantum dots in which electrohydrodynamic jet printing is used to control the position of the quantum dots within the device structure. This results in significantly less waste of the quantum dot material and the targeted placement of the quantum dots minimizes any emission outside of the resonant enhancement field, enabling an 8X output enhancement and highly polarized emission from the photonic crystal structure.

关键词： Wavelength measurement Substrates

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Needle-implantable, wireless biosensor for continuous glucose monitoring 12

Needle-implantable, wireless biosensor for continuous glucos...

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12th IEEE International Conference on Wearable and Implantable Body Sensor Networks, BSN 2015

作者： Vaddiraju, Santhisagar Kastellorizios, Michail Legassey, Allen Burgess, Diane Jain, Faquir Papadimitrakopoulos, Fotios Biorasis Inc. Technology Incubation Program University of Connecticut StorrsCT06268 United States Nanomaterials Optoelectronics Laboratory Institute of Materials Science University of Connecticut StorrsCT06269 United States Electrical and Computer Engineering University of Connecticut StorrsCT06269 United States Department of Pharmaceutical Sciences University of Connecticut StorrsCT06269 United States Department of Chemistry University of Connecticut StorrsCT06269 United States

ISBN: (纸本)9781467372015

Unlike non-invasive and minimally invasive continuous monitoring of glucose (CGM) devices, invasive devices require less rigorous calibration and exhibit smaller subject-to-subject variability. Biorasis, Inc. and the University of Connecticut are developing a totally implantable CGM device. Glucowizzard™ is engineered at the smallest possible footprint (0.5 × 0.5 × 5 mm). This miniaturization is made possible by utilizing light both for powering and wireless communication. In addition, Glucowizzard™ utilizes 'smart' hydrogel coatings intended for localized release of various tissue response modifiers for effective control of negative tissue responses. The use of light-based powering and communication together with advanced microelectronic design rules has allowed the fabrication of truly miniaturized CGM device. The drug delivery coating has enabled substantial reduction of negative tissue responses for up to 1 month in small as well as large animals (rats and minipigs). The functionality of Glucowizzard™ has been demonstrated in vivo in both rats and minipigs. © 2015 IEEE.

关键词： Rats

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Bioprinting: High‐Resolution Projection Microstereolithography for Patterning of Neovasculature (Adv. Healthcare Mater. 5/2016)

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Advanced Healthcare Materials 2016年第5期5卷

作者： Ritu Raman Basanta Bhaduri Mustafa Mir Artem Shkumatov Min Kyung Lee Gabriel Popescu Hyunjoon Kong Rashid Bashir Department of Mechanical Science and Engineering Micro and Nanotechnology Laboratory University of Illinois at Urbana‐Champaign Urbana IL 61801 USA Department of Electrical and Computer Engineering Beckman Institute for Advanced Science University of Illinois at Urbana‐Champaign Urbana IL 61801 USA Department of Molecular and Cell Biology University of California Berkeley Berkeley CA 94720 USA Department of Pathobiology Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana‐Champaign Urbana IL 61801 USA Department of Chemical and Biomolecular Engineering Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana‐Champaign Urbana IL 61801 USA Department of Bioengineering and Electrical and Computer Engineering Micro and Nanotechnology Laboratory University of Illinois at Urbana‐Champaign Urbana IL 61801 USA

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Direct observation of symmetry-specific precession in a ferrimagnet

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Physical Review B 2015年第10期92卷 104402-104402页

作者： P. Warnicke E. Stavitski J.-S. Lee A. Yang Z. Chen X. Zuo S. Zohar W. E. Bailey V. G. Harris D. A. Arena Photon Sciences Directorate Brookhaven National Laboratory Upton New York 11973 USA Department of Electrical and Computer Engineering Northeastern University Boston Massachusetts 02115 USA Materials Science Program Department of Applied Physics Columbia University New York New York 10027 USA

Here we demonstrate an experimental observation of GHz-scale spin dynamics resolved to sublattice octahedral (Oh) tetrahedral (Td) sites in a spinel ferrimagnet, in this case a Mn-ferrite thin film. X-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) are used, in combination with multiplet calculations, to uniquely identify the spectral signature from Mn2+ and Fe2+,3+ on Oh and Td lattice sites. With the sample under rf excitation, the spin alignment of the sublattices is tracked with time-resolved XMCD (TR-XMCD). The spin alignment of the sublattices is mostly antiferromagnetic. The phase difference between the Oh Fe2+ [Oh Fe3+] and Td Mn2+ sites is 181.2±3.8∘ [183.3∘±3.7∘] at 150 K and 186.6±2.2∘ [182.0∘±2.2∘] at 300 K. Such direct measurement of the dynamic coupling, exchange stiffness, and damping enabled by TR-XMCD across sublattices will be essential for optimizing the development of future-generation microwave devices.

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Toward Non-Hair-Bearing Brain-computer Interfaces for Neurocognitive Lapse Detection

Toward Non-Hair-Bearing Brain-Computer Interfaces for Neuroc...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Chun-Shu Wei Yu-Te Wang Chin-Teng Lin Tzyy-Ping Jung the Swartz Center of Computational Neuroscience (SCCN) Center for Advanced Neurological Engineering (CANE) and Department of Bioengineering University of California San Diego (UCSD) La Jolla CA USA SCCN CANE and the Department of Computer Science and Engineering UCSD La Jolla CA USA the Brain Research Center and the Department of Electrical Engineering National Chiao Tung University Hsinchu Taiwan

ISBN: (纸本)9781424492695

Recent advances in mobile electroencephalogram (EEG) acquisition based on dry electrodes have started moving Brain-computer Interface (BCI) applications from well-controlled laboratory settings to real-world environments. However, the application mechanisms and high impedance of dry electrodes over the hair-covered areas remain challenging for everyday use of BCI. In addition, whole-scalp recordings are not always necessary or applicable due to various practical constrains. Therefore, alternative montages for EEG recordings to meet the everyday needs are in-demand. Inspired by our previous work on measuring non-hair-bearing steady state visual evoked potentials for BCI applications, this study explores the feasibility and efficacy of detecting cognitive lapses of participants based on EEG signals collected from the non-hair-bearing areas. Study results suggest that informative EEG features associated with lapses could be assessed from non-hair-bearing areas with comparable accuracy obtained from the whole-scalp EEG. The design principles, validation processes and promising findings reported in this study may enable and/or facilitate numerous BCI applications in real-world environments.

关键词： EEG BCI non-hair-bearing areas

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