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Deformation of Porous, Nanostructured Silver at Room Temperature and 150 °C

MRS Online Proceedings Library 2013年第1期1513卷 1-6页

作者： Noiseau, Guillaume Becker, Michael F. Keto, John W. Kovar, Desiderio Materials Science and Engineering Graduate Program The University of Texas at Austin Austin USA Department of Electrical and Computer Engineering The University of Texas Austin USA Department of Physics The University of Texas Austin USA Department of Mechanical Engineering The University of Texas Austin USA

Porous, nanostructured silver samples were produced using a direct-write method where a nanoparticle aerosol consisting of particles with a mean size of approximately 5 nm were accelerated to speeds of approximately 1000 m/sec and impacted onto a translating substrate [1]. The impacting particles have sufficient energy to stick to the substrate, allowing patterned thick films to be directly written from the aerosol without a mask. Unlike other low temperature processing routes for achieving patterned films, no organics are added that can interfere with postdeposition processing. Typical films are 5- 100 μm thick, up to several centimeters long, and have an as-deposited relative densities as high as 70% of bulk Ag. Compression tests were carried out in steps at room temperature and at 150°C under constant displacement rates. Local strain and densification were measured by optical profilometry between each compression step. The results can be used as a starting point to better understand the mechanisms that govern plasticity, creep, and sintering in nanostructured, porous silver at low processing temperatures.

关键词： Ag densification nanoscale

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Validating a new methodology for strain estimation from cardiac cine MRI

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AIP Conference Proceedings 2013年第1期1559卷 277-286页

作者： Ahmed Elnakib Garth M. Beache Georgy Gimel'farb Tamer Inanc Ayman El-Baz BioImaging Laboratory Bioengineering Department University of Louisville Louisville KY USA Department of Diagnostic Radiology School of Medicine University of Louisville Louisville KY USA Department of Computer Science University of Auckland Auckland New Zealand Department of Electrical and Computer Engineering University of Louisville Louisville KY USA

This paper focuses on validating a novel framework for estimating the functional strain from cine cardiac magnetic resonance imaging (CMRI). The framework consists of three processing steps. First, the left ventricle (LV) wall borders are segmented using a level-set based deformable model. Second, the points on the wall borders are tracked during the cardiac cycle based on solving the Laplace equation between the LV edges. Finally, the circumferential and radial strains are estimated at the inner, mid-wall, and outer borders of the LV wall. The proposed framework is validated using synthetic phantoms of the material strains that account for the physiological features and the LV response during the cardiac cycle. Experimental results on simulated phantom images confirm the accuracy and robustness of our method.

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A new shape-based framework for the left ventricle wall segmentation from cardiac first-pass perfusion mri

A new shape-based framework for the left ventricle wall segm...

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IEEE International Symposium on Biomedical Imaging

作者： F. Khalifa G. M. Beache A. Elnakib H. Sliman G. Gimel'farb K. C. Welch A. El-Baz Bioengineering Department University of Louisville Louisville KY USA Radiology Department School of Medicine University of Louisville Louisville KY USA Department of Computer Engineering and Computer Science University of Louisville Louisville KY USA Department of Computer Science University of Auckland Auckland New Zealand Electrical and Computer Engineering Department University of Louisville Louisville KY USA

ISBN: (纸本)9781467364560

We propose a shape-based approach for the segmentation of the left ventricle (LV) wall on cardiac first-pass magnetic resonance imaging (FP-MRI) using level sets. To reduce the variabilities of the LV wall in FP-MRI, it is first imperative to co-align the time series images to account for the global and local motions of the heart. Therefore, we developed a two-step registration methodology that includes an affine-based registration followed by a local B-splines based alignment to maximize a similarity function that accounts for the first- and second-order normalized mutual information (NMI). Additionally, myocardial signal intensity varies with the agent transit, which makes it difficult to control the level set evolution using image intensities alone. Thus, we constrained the level set evolution using three features: a weighted probabilistic shape prior, the first-order pixel-wise image intensities, and a second-order Markov-Gibbs random field (MGRF) spatial interaction model. We tested our approach on 24 data sets in 8 infarction patients using the Dice similarity coefficient (DSC), comparing our approach to other shape-based segmentation approaches. We also tested the performance of our segmentation approach using the receiver operating characteristics (ROC). Our approach achieved a mean DSC value of 0.910±0.037 compared to other shape-based methods that achieved 0.862±0.045 and 0.844±0.047. Finally, the ROC analysis for our segmentation method showed the best performance, with area under the ROC curve of 0.92, while that for intensity showed the worst performance, with area under the ROC curve of 0.69.

关键词： Image segmentation Shape Magnetic resonance imaging Myocardium Biomedical imaging Level set Time series analysis

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Twin-T Oscillator Containing Polymer Coated Parallel Plate Capacitor for Sea Water Salinity Sensing

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Open Journal of Applied Biosensor 2013年第2期2卷 57-64页

作者： Shreyas Bhatt Abdur Rub Abdur Rahman Sunil K. Arya Shekhar Bhansali Bioelectronics Program Institute of Microelectronics A*Star Singapore Science Park II Singapore City Singapore BioMEMS and Microsystems Lab Department of Electrical Engineering University of South Florida Tampa USA Department of Electrical and Computer Engineering Florida International University Miami FL USA

This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity *** sensor employs a parallel plate capacitor design, with sea water serving as the medium between plates. Novalac resin and a proprietary commercial polymer (AccufloTW) were investigated as corrosion protective coatings for the copper electrodes of the capacitor. Electrochemical Impedance Spectroscopy (EIS) was employed to evaluate corrosion inhibition of polymer coatingin sea water. A detection circuit was designed and simulated using P-spice and then implemented in Printed Circuit Board (PCB). EIS results indicate that Accuflo exhibits better corrosion inhibition in ocean water than Novolac. Further, the use of Twin-T oscillator based detection circuit resulted in enhanced sensitivity and better detection limit. Experiments performed using ocean water samples resulted in oscillator frequency shift of 410 Hertz/power supply unit (Hz/PSU). Oscillator frequency drift was reduced using frequency-to-voltage converters and sensitivity of 10 mV/PSU was achieved.

关键词： Impedance Spectroscopy Salinity Sensing Capacitive Sensors Polymer Coating Twin-T Oscillator

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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Periodic dynamics, localization metastability, and elastic interaction of colloidal particles with confining surfaces and helicoidal structure of cholesteric liquid crystals

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Physical Review E 2014年第6期90卷 062502-062502页

作者： Michael C. M. Varney Qiaoxuan Zhang Mykola Tasinkevych Nuno M. Silvestre Kris A. Bertness Ivan I. Smalyukh Department of Physics University of Colorado at Boulder Boulder Colorado 80309 USA Materials Science and Engineering Program University of Colorado at Boulder Boulder Colorado 80309 USA Max-Planck-Institut für Intelligente Systeme D-70569 Stuttgart Germany Institut für Theoretische Physik IV Universität Stuttgart D-70569 Stuttgart Germany Centro de Física Teórica e Computacional and Faculdade de Ciências da Universidade de Lisboa Av. Prof. Gama Pinto 2 1649-003 Lisboa Portugal National Institute of Standards and Technology Boulder Colorado 80305 USA Department of Electrical Computer and Energy Engineering and Liquid Crystals Materials Research Center University of Colorado at Boulder Boulder Colorado 80309 USA Renewable and Sustainable Energy Institute National Renewable Energy Laboratory and University of Colorado at Boulder Boulder Colorado 80309 USA

Nematic and cholesteric liquid crystals are three-dimensional fluids that possess long-range orientational ordering and can support both topological defects and chiral superstructures. Implications of this ordering remain unexplored even for simple dynamic processes such as the ones found in so-called “fall experiments,” or motion of a spherical inclusion under the effects of gravity. Here we show that elastic and surface anchoring interactions prompt periodic dynamics of colloidal microparticles in confined cholesterics when gravity acts along the helical axis. We explore elastic interactions between colloidal microparticles and confining surfaces as well as with an aligned ground-state helical structure of cholesterics for different sizes of spheres relative to the cholesteric pitch, demonstrating unexpected departures from Stokes-like behavior at very low Reynolds numbers. We characterize metastable localization of microspheres under the effects of elastic and surface anchoring periodic potential landscapes seen by moving spheres, demonstrating the important roles played by anchoring memory, confinement, and topological defect transformation. These experimental findings are consistent with the results of numerical modeling performed through minimizing the total free energy due to colloidal inclusions at different locations along the helical axis and with respect to the confining substrates. A potential application emerging from this work is colloidal sorting based on particle shapes and sizes.

关键词： Cholesteric liquid crystals

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Gradient field microscopy for label-free diagnosis of human biopsies [Invited]

Gradient field microscopy for label-free diagnosis of human ...

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作者： Kim, Taewoo Sridharan, Shamira Kajdacsy-Balla, André Tangella, Krishnarao Popescu, Gabriel Quantitative Light Imaging Laboratory Department of Electrical and Computer Engineering Beckman Institute for Advanced Science and Technology Urbana IL 61801 United States Quantitative Light Imaging Laboratory Department of Bioengineering Beckman Institute for Advanced Science and Technology Urbana IL 61801 United States University of Illinois at Chicago Department of Pathology Chicago IL 60612 United States Christie Clinic Department of Pathology University of Illinois at Urbana-Champaign Urbana IL 61801 United States

We introduce a label-free method for detecting high-grade prostatic intraepithelial neoplasia (HGPIN) in unstained biopsies. We image this condition based on the identification of basal cells in biopsies that otherwise would resemble prostate cancer by unassisted histologic examination. Gradient field microscopy (GFM) is used as a label-free imaging method which increases the contrast of a transparent sample by taking the first-order phase derivative that is very sensitive to rapid refractive index changes. GFM is able to image the basal cell layers in HGPIN biopsies because of their rapid refractive index changes at the periphery of small glandular structures. © 2012 Optical Society of America.

关键词： Biopsy

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Recent Advances in Detection of Ochratoxin-A

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Open Journal of Applied Biosensor 2013年第1期2卷 1-11页

作者： Ajeet Kaushik Sunil K. Arya Abhay Vasudev Shekhar Bhansali Bioelectronics Program Institute of Microelectronics A*STAR (Agency for Science Technology and Research) 11 Science Park Road Singapore Science Park II Singapore 117685 Singapore Bio-MEMS and Microsystems Lab Department of Electrical and Computer Engineering Florida International University Miami USA Bio-MEMS and Microsystems Lab Department of Electrical and Computer EngineeringFlorida International University Miami USA Department of Biomedical Engineering Florida International University Miami USA

Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.

关键词： Biopolymer Mycotoxins Ochratoxin-A Chitosan Organic-Inorganic Hybrid Nanocomposite Biosensors

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Steep subthreshold slope nanowire nanoelectromechanical field-effect transistors (NW-NEMFETs)

Steep subthreshold slope nanowire nanoelectromechanical fiel...

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Berkeley Symposium on Energy Efficient Electronic Systems (E3S)

作者： Ji-Hun Kim Zack C. Y. Chen Soonshin Kwon Jie Xiang Department of Electrical and Computer Engineering University of California San La Jolla CA Department of Materials Science Program University of California San La Jolla CA

Significant physical challenges remain for CMOS technology to decrease I off as transistor dimension and power supply voltages continue downscaling. However, a fundamental thermodynamic limit in the subthreshold slope SS = |(∂V g )/(∂lnI d )| = ln10 · k B T/q at >60 mV/dec exists at room temperature. We have designed and demonstrated the first semiconductor nanowires (NWs) and nanoelectromechanical system (NEMS) field effect transistor structure (NW-NEMFET). We have previously demonstrated 0.5 ps intrinsic delay and near ballistic operation in quantum confined semiconductor heterostructure NWFETs with diameters less than 15 nm.[1] The current design uses high performance suspended semiconductor NWs as the conduction channel, while the electrostatic pull-in of the NW towards the gate stack enables abrupt switching to the off-state leading to high frequency, low power nanoelectronics. Simulation shows that compared to planar suspended-gate FET (SGFET) design [2], NW-NEMFET allows zero SS with 10 15 on-off ratio and near 1V pull-in voltage due to enhanced 3D capacitive coupling, as well as operation at very-high-frequency (VHF) and even ultra-high-frequency (UHF) due to the NW beams high aspect ratio and small dimensions.

关键词： Logic gates Silicon Electrodes Couplings Electrostatics Three-dimensional displays Transistors

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Multi-hole defect photonic crystals with enhanced surface area for biosensing applications

Multi-hole defect photonic crystals with enhanced surface ar...

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Laser science, LS 2013

作者： Hu, S. Kang, C. Zhao, Y. Mares, J.W. Vlasov, Y.A. Assefa, S. Weiss, S.M. Department of Physics and Astronomy Vanderbilt University Nashville TN 37235 United States Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN 37235 United States IBM T.J. Watson Research Center Yorktown Heights NY 10536 United States

Multi-hole defect (MHD) photonic crystal cavities functionalized with in situ synthesized DNA bioreceptors are demonstrated for biosensing applications. By significantly increasing light interaction with target biomol... 详细信息

ISBN: (纸本)9781557529879

关键词： Photonic crystals

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