This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity *** sensor employs a parallel plate capacitor design, with sea water serving as...
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This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity *** sensor employs a parallel plate capacitor design, with sea water serving as the medium between plates. Novalac resin and a proprietary commercial polymer (AccufloTW) were investigated as corrosion protective coatings for the copper electrodes of the capacitor. Electrochemical Impedance Spectroscopy (EIS) was employed to evaluate corrosion inhibition of polymer coatingin sea water. A detection circuit was designed and simulated using P-spice and then implemented in Printed Circuit Board (PCB). EIS results indicate that Accuflo exhibits better corrosion inhibition in ocean water than Novolac. Further, the use of Twin-T oscillator based detection circuit resulted in enhanced sensitivity and better detection limit. Experiments performed using ocean water samples resulted in oscillator frequency shift of 410 Hertz/power supply unit (Hz/PSU). Oscillator frequency drift was reduced using frequency-to-voltage converters and sensitivity of 10 mV/PSU was achieved.
O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell ...
O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me
Reflection and refraction of electromagnetic waves by artificial periodic composites (metamaterials) can be accurately modeled by an effective medium theory only if the boundary of the medium is explicitly taken into ...
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Reflection and refraction of electromagnetic waves by artificial periodic composites (metamaterials) can be accurately modeled by an effective medium theory only if the boundary of the medium is explicitly taken into account and the two effective parameters of the medium (the index of refraction and the impedance) are correctly determined. Theories that consider infinite periodic composites do not satisfy the above condition. As a result, they can not model reflection and transmission by finite samples with the desired accuracy and are not useful for design of metamaterial-based devices. As an instructive case in point, we consider the “current-driven” homogenization theory, which has recently gained popularity. We apply this theory to the case of one-dimensional periodic medium wherein both exact and homogenization results can be obtained analytically in closed form. We show that, beyond the well-understood zero-cell limit, the current-driven homogenization result is inconsistent with the exact reflection and transmission characteristics of the slab.
Nematic and cholesteric liquid crystals are three-dimensional fluids that possess long-range orientational ordering and can support both topological defects and chiral superstructures. Implications of this ordering re...
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Nematic and cholesteric liquid crystals are three-dimensional fluids that possess long-range orientational ordering and can support both topological defects and chiral superstructures. Implications of this ordering remain unexplored even for simple dynamic processes such as the ones found in so-called “fall experiments,” or motion of a spherical inclusion under the effects of gravity. Here we show that elastic and surface anchoring interactions prompt periodic dynamics of colloidal microparticles in confined cholesterics when gravity acts along the helical axis. We explore elastic interactions between colloidal microparticles and confining surfaces as well as with an aligned ground-state helical structure of cholesterics for different sizes of spheres relative to the cholesteric pitch, demonstrating unexpected departures from Stokes-like behavior at very low Reynolds numbers. We characterize metastable localization of microspheres under the effects of elastic and surface anchoring periodic potential landscapes seen by moving spheres, demonstrating the important roles played by anchoring memory, confinement, and topological defect transformation. These experimental findings are consistent with the results of numerical modeling performed through minimizing the total free energy due to colloidal inclusions at different locations along the helical axis and with respect to the confining substrates. A potential application emerging from this work is colloidal sorting based on particle shapes and sizes.
We introduce a label-free method for detecting high-grade prostatic intraepithelial neoplasia (HGPIN) in unstained biopsies. We image this condition based on the identification of basal cells in biopsies that otherwis...
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Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly sto...
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Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.
Significant physical challenges remain for CMOS technology to decrease I off as transistor dimension and power supply voltages continue downscaling. However, a fundamental thermodynamic limit in the subthreshold slop...
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Significant physical challenges remain for CMOS technology to decrease I off as transistor dimension and power supply voltages continue downscaling. However, a fundamental thermodynamic limit in the subthreshold slope SS = |(∂V g )/(∂lnI d )| = ln10 · k B T/q at >60 mV/dec exists at room temperature. We have designed and demonstrated the first semiconductor nanowires (NWs) and nanoelectromechanical system (NEMS) field effect transistor structure (NW-NEMFET). We have previously demonstrated 0.5 ps intrinsic delay and near ballistic operation in quantum confined semiconductor heterostructure NWFETs with diameters less than 15 nm.[1] The current design uses high performance suspended semiconductor NWs as the conduction channel, while the electrostatic pull-in of the NW towards the gate stack enables abrupt switching to the off-state leading to high frequency, low power nanoelectronics. Simulation shows that compared to planar suspended-gate FET (SGFET) design [2], NW-NEMFET allows zero SS with 10 15 on-off ratio and near 1V pull-in voltage due to enhanced 3D capacitive coupling, as well as operation at very-high-frequency (VHF) and even ultra-high-frequency (UHF) due to the NW beams high aspect ratio and small dimensions.
Multi-hole defect (MHD) photonic crystal cavities functionalized with in situ synthesized DNA bioreceptors are demonstrated for biosensing applications. By significantly increasing light interaction with target biomol...
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We demonstrate the superior inductive properties of coiled carbon nanotubes (CCNTs) through numerical computation and analytical modeling, for the next generation of nanoscale, on-chip inductors. Taking advantage of t...
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We demonstrate the superior inductive properties of coiled carbon nanotubes (CCNTs) through numerical computation and analytical modeling, for the next generation of nanoscale, on-chip inductors. Taking advantage of the kinetic inductance (Lk), particularly evident at the nanoscale we find that the inductance can be increased by three orders of magnitude through changing the tube radius as well as the coil radius while the device footprint of the CCNTs can be reduced by 60%. By varying the geometric parameters of the coiled structure, the external magnetic inductance (LM,ext) can be as high as 20% of the Lk. We also report that the self resonant frequency (fSR) of CCNTs can be as much of the order of THz whereas the fSR of conventional copper(Cu) spiral inductors are limited to around 40GHz. Moreover when the material volume is considered, CCNTs have the potential to achieve Quality Factor (Q) eight times as Cu and when the footprint volume is considered Q can be twice as Cu All these promising properties of CCNTs make them a potential candidate for the entire frequency spectrum.
This paper proposes the use of Group Method of Data Handling (GMDH) technique for modeling Magneto-Rheological (MR) dampers in the context of system identification. GMDH is a multilayer network of quadratic neurons th...
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This paper proposes the use of Group Method of Data Handling (GMDH) technique for modeling Magneto-Rheological (MR) dampers in the context of system identification. GMDH is a multilayer network of quadratic neurons that offers an effective solution to modeling non-linear systems. As such, we propose the use of GMDH to approximate the forward and inverse dynamic behaviors of MR dampers. We also introduce two enhanced GMDH-based solutions. Firstly, a two-tier architecture is proposed whereby an enhanced GMD model is generated by the aid of a feedback scheme. Secondly, stepwise regression is used as a feature selection method prior to GMDH modeling. The proposed enhancements to GMDH are found to offer improved prediction results in terms of reducing the root-mean-squared error by around 40%.
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