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The Effects of Microwave Radiation, Hyperthermia, and L-Ascorbic Acid on Ehrlich Ascites Carcinoma Cell Metabolism

IEEE Transactions on Microwave Theory and Techniques 1978年第8期26卷 535-540页

作者： Piontek, Gerald E. Cain, Charles A. Radiation Oncology Training Program post-doctoral fellow University of Illinois Urbana II United States Bioacoustics Research Laboratory Department of Electrical Engineering Bioengineering Faculty University of Illinois Urbana II United States Department of Food Science School of Basic Medical Sciences Universitv of Illinois Urbana II United States

The effects of microwave radiation, hyperthermia, and L-ascorbic acid on metabolism of (U_14C) glucose, (2-14°C) glucose, and (1,5-l4C) citrate in Ehrlich ascites tumor cells (EATC) were studied. Microwave irradiated and water bath incubated cells were maintained at the same temperature for comparison. Data were obtained at 37.5°C and 42.5°C in the presence or absence of L-ascorbic acld, Ascorbilc acid increased the rate of metabolism of both glucose and citrate. No significant differences in glucose and citrate metabolism were found between irradiated and nonirradiated cells at the same temperature and ascorbic acid concentration. A comparison of glucose metabolism in a normal tissue preparation and EATC was made. Vitamin C did not increase metabolism in the normal cell preparation. Copyright © 1978 by The Institute of electrical and Electronics Engineers, Inc.

关键词： Hyperthermia Biochemistry Electromagnetic heating Sugar Water heating Neoplasms Cancer Temperature Oncology

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Abstracts

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Environmental Management 1977年第1期1卷 67-96页

作者： Frankenfeld, John W. Schulz, Wolfgang McMurty, George J. Petersen, Gary W. May, G. A. Hering, F. S. Schwartz, J. I. Heywood, J. B. Chigier, N. A. Grohse, E. W. Walker, J. D. Colwell, R. R. Petrakis, L. Pergament, H. S. Thorpe, R. D. Schoepf, Richard W. Krzyczkowski, Roman Henneman, Suzanne S. Hudson, Charles L. Putnam, Evelyn S. Thiesen, Donna J. Parks, G. A. McCarty, Perry L. Leckie, J. O. Schrumpf, Barry J. Simonson, G. H. Paine, D. P. Lawrence, R. D. Pyott, W. T. Leh, M. Elders, W. Combs, J. Caplen, T. Harrison, F. L. Wong, K. M. Heft., R. E. Charnell, Robert L. Lehmann, Edward J. Mallon, Lawrence G. Hatfield, Cecile Adams, Gerald H. Johanning, James Talvitie, Antti Noll, Kenneth E. Miller, Terry Smiarowski, Joseph F. Willis, Cleve E. Foster, John H. Schlesinger, Benjamin Daetz, Douglas Lear, Donald U. Smith, Mona F. Hundemann, Audrey S. Crockett, Pernell W. Werner, Kirk G. Carroll, Thomas E. Maase, David L. Genco, Joseph E. Ifeadi, Christopher N. Lowman, F. G. Christensen, S. W. Van Winkle, W. Mattice, J. S. Harrison, Elizabeth A. Barker, James C. Chesness, Jerry L. Smith, Ralph E. Shaheeen, Donald G. Raney, R. Keith Borton, T. Wezernak, C. T. Raney, R. K. Sherwani, Jabbor K. Moreau, David H. Eisenberg, Norman A. Lynch, Cornelius J. Breeding, Roger J. Johnson, J. D. Foster, K. E. Mouat, D. A. Clark, R. Hyden, John William Owen, Wilfred Bayfield, Neil G. Barrow, Graham C. Stolz, Stephanie B. Wienckowski, Louis A. Brown, Betram S. Keyfitz, Nathan Wilson, W. L. Newman, Peter W. G. Bammi, Deepak Bammi, Dalip Goddard, James E. Chisholm, Tony Walsh, Cliff Brennan, Geoffrey Thompson, K. S. Richardson, R. Jensen, Clayton E. Brown, Dail W. Mirabito, John A. Cowing, Thomas G. Binghamton, Suny Siehl, George H. Albrecht, O. W. Alexander, Ariel Barde, Jean -Philippe Darby, William P. McMichael, Francis Clay Dunlap, Robert W. Muckleston, Keith W. Frankenhoff, Charles A. Giulini, Lorenzo T. Wyatt, T. Black, Peter E. Keating, William Thomas Leonard, M. E. Fisher, E. L. Brunelle, M. F. Dickinson, J. E. Pethig, Rudiger Clapham Exxon Research & Engineering Co. Linden Government Research Lab Coast Guard Washington D.C. Department of Transportation Washington D.C. Office For Remote Sensing of Earth Resources. NASA Earth Resources Survey Program Pennsylvania State University Washington D.C. Department of the Navy Washington D.C. Cambridge. Dept. of Mechanical Engineering Massachusetts Inst. of Technology USA Huntsville. School of Graduate Studies and Research Alabama Univ. USA Dept. of Microbiology. Office of Naval Research Maryland Univ. Arlington Research and Development Co. Pittsburgh AeroChem Research Labs. Inc. Princeton Dept. of the Interior Office of Library Services. Bibliographic Series (Final) Washington D.C. Interplan Corp. Santa Barbara Urban Mass Transportation Adm. Washington D.C. Naval Underwater Systems Center Newport Calif. Mercury Project. National Science Found Stanford Univ Washington D.C. Div. of Advanced Environmental Research & Tech. USA Corvallis. NASA Earth Resources Survey Program Oregon State Univ. Washington D.C. Riverside. Inst. of Geophysics and Planetary Physics National Science Foundation California Univ. Washington D.C. Livermore Lawrence Livermore Lab. California Univ. USA Atlantic Oceanographic and Meteorological Labs. National Oceanic and Atmospheric Administration Miami National Technical Information Service Springfield Miami Univ. Coral Gables School of Law National Oceanic and Atmospheric Administration Rockville National Academy of Sciences Office of Sea Grant Washington D. C. School of Law National Oceanic and Atmospheric Administration Office of Sea Grant. Rockville Norman. Dept. of Civil Engineering and Environmental Science. Urban Mass Transportation Administration Oklahoma Univ. Washington D. C. Knoxville.Dept. of Civil Engineering. Federal Highway Administration Tennessee Univ. Washington D. C. Amherst.Water Resources Research Center. Office of Water Research and Technology Massachusetts Univ. Washington D. C. Calif. Dept. of Industria

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A Flexible Renewal Process Simulator for Neural Spike Trains

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IEEE Transactions on Biomedical engineering 1976年第3期BME-23卷 262-266页

作者： Belanger, Barry F. Williams, William J. Yin, Tom C. T. Bioelectrical Sciences Laboratory Department of Electrical and Computer Engineering and the Bioengineering Program University of Michigan Ann Arbor MI 48109. United States

Certain neuronal spike trains may be viewed as stochastic, nonhomogeneous point process. Neuronal information may be encoded in the time-varying mean rate of the spike train in some cases. For this purpose the simulat... 详细信息

关键词： Humans Heart Bioelectric phenomena Testing Cardiology Myocardium Neurons Laboratories Thorax Signal analysis

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On the Properties of Irredundant Logic Networks

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IEEE Transactions on computers 1976年第9期C-25卷 884-892页

作者： Hayes, John P. Department of Electrical Engineering Computer Science Program University of Southern California Los Angeles CA 90007 United States

The constraints imposed by various types of irredundancy on the structure of combinational logic networks are investigated. It is shown that the usual notion ofirredundancy here called a-irredundancy, places bounds on the maximum number of inputs to certain types of network structures. A network is called b-redundant if it contains a cascade of single-input gates that can be reduced to either an inverter or a single line. Let Nab(Z) denote all realizations of Z that are both a - and b-irredundant. If N E Nab(Z), then the number of gates in any fan-out-free subnetwork of N is bounded. It is shown that a solution to some important design optimization problems can be found in Nab(Z). It is conjectured that Nab(Z) is finite and some results supporting this conjecture are presented. For example, it is impossible to construct an arbitrarily long cascade of networks that perform the identity transformation without introducing a-or b-redundancy. A more general type of redundancy, c-redundancy, is defined which includes both a-and b-redundancy as special cases. The class of c-irredundant realizations of Z is finite. Copyright © 1976 by The Institute of electrical and Electronics Engineers, Inc.

关键词： Combinational networks irredundant networks logic circuits logic design optimization redundancy redundancy testing redundancy types

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A Graph Model for Fault-Tolerant Computing Systems

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IEEE Transactions on computers 1976年第9期C-25卷 875-884页

作者： Hayes, John P. Department of Electrical Engineering Computer Science Program University of Southern California Los Angeles CA 90007 United States

An approach to fault-tolerant design is described in which a computing system S and an algorithm A to be executed by S are both defined by graphs whose nodes represent computing facilities. A is executable by S if A is isomorphic to a subgraph of S. A k-fault is the removal of k nodes (facilities) from S. S is a k-faulttolerant (k-FT) realization of A if A can be executed by S with any k-fault present in S. The problem of designing optimal k-FT systems is considered where A is equated to a 0-FT system. Techniques are described for designing optimal k-FT realizations of single-loop systems;these techniques are related to results in Hamiltonian graph theory. The design of optimal k-FT realizations of certain types of tree systems is also examined. The advantages and disadvantages of the graph model are discussed. Copyright © 1976 by The Institute of electrical and Electronics Engineers, Inc.

关键词： computer architecture fault-tolerant computing fault-tolerant design graph theory Hamiltonian graphs singleloop systems tree systems

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Optimal Placement of Software Monitors Aiding Systematic Testing

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IEEE Transactions on Software engineering 1975年第4期SE-1卷 403-411页

作者： Ramamoorthy, C.V. Kim, K.H. Chen, W.T. Computer Science Division Department of Electrical Engineering and Computer Sciences University of California Berkeley Calif 94720 United States Department of Electrical Engineering Systems and Computer Science Program University of Southern California Los Angeles Calif. United States

The usefulness of software monitors in testing large ‘programs is discussed. Several types of testing strategies based on the use of monitors are surveyed. Since there is a computational overhead involved in employing monitors, attempts are made to minimize the number of monitors employed. This optimization problem is formulated and analyzed in graph-theoretic terms. Implementation aspects are considered through both discussion and examples. Copyright © 1975 by The Institute of electrical and Electronics Engineers, Inc.

关键词： Optimal placement overhead program testing software monitor test-input test-output test-path test-run

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The Fanout Structure of Switching Functions

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Journal of the ACM (JACM) 1975年第4期22卷 551-571页

作者： Hayes, John P. Department of Electrical Engineering and Computer Science Program University of Southern California Los Angeles CA 90007 United States

The problem of determining the amount of fanout required to reahze a switching function m investigated. The significance of fanout in switching networks is discussed Fanout-free functions are introduced and their propertms examined. Two relations, adjacency and masking, are defined on the variables X of a functlon f(X), and these relations are used to characterize fanoutfree functions A quantity τ(f) called the input fanout index of f is defined for arbitrary switching functions;τ(f) represents the minimum number of input variables that require fanout in any reahzation of ff It is shown that τ(f) can be determined from the pmme lmphcants and prime imphcates of f using two additmnal relations on X, the conjugate property and compatibility An algorithm is presented for finding a reahzatlon of f in whmh only τ(f) variables fan out. Some other measures of fanout are briefly considered. © 1975, ACM. All rights reserved.

关键词： fanout fanout-free functions fanout-free networks Input fanout index mimmlzatlon of fanout partially fanout-free functtons switching functions

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On Modifying Logic Networks to Improve Their Diagnosability

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IEEE Transactions on computers 1974年第1期C-23卷 56-62页

作者： Hayes, John P. Department of Electrical Engineering and Computer Science Program University of Southern California Los Angeles Calif. 90007 United States

This paper considers the use of control logic to reduce the number of tests required by a logic network and to simplify test generation. The properties of EXCLUSIVE-OR (EOR) circuits as control elements are examined. Systematic procedures are presented for modifying any combinational or sequential network so that the resulting network requires only five tests. These tests can easily be generated using a set of predefined test patterns of length five. The design of diagnosable networks using a limited amount of control logic is also discussed. © 1974, IEEE. All rights reserved.

关键词： Control logic diagnosable logic networks fault diagnosis improving diagnosability test reduction

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Curriculum on design automation at the University of Southern California 74

Curriculum on design automation at the University of Souther...

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1974 Annual ACM Conference/Annual Meeting, ACM 1974

作者： Breuer, Melvin A. Electrical Engineering Department and Computer Science Program University of Southern California Los AngelesCA90007 United States

ISBN: (纸本)9781450378505

During the 1969-70 academic year we introduced a course here at USC dealing with the use of computers in the design of digital system. This was probably the first such course of its kind instituted on a regular basis in the United States. The idea for such a course came from my colleagues in the special interests group on Design Automation of the IEEE computer Group. Their primary goal for such a course was to instill the basic concepts of computer aided design into our new graduates. This paper reviews the major aspects related to this course on computer design. Hopefully, other schools will be motivated to develop similar courses. It is interesting to note that in a recent issue of Spectrum [5], W. R. Beam states that "... every digital designer needs to know something about design automation, even if he's only going to build a single system." For this reason, a book on design automation [1] is one of his eleven essential books for the digital designer's reference and study library. 1974 ACM. All rights reserved.

关键词： computer aided design

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Initial design concepts for an advanced design automation system 12

Initial design concepts for an advanced design automation sy...

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12th Annual ACM IEEE Design Automation Conference, DAC 1974

作者： Breuer, Melvin A. Friedman, A.D. Department of Electrical Engineering and Computer Science Program University of Southern California Los AngelesCA90007 United States

Most design automation systems attempt to automate only a small part of the physical description. Much is left to the designers. An exploratory design automation system is being developed at the University of Southern California. The system is intended to be highly interactive and has several features which will enhance the possibilities of automatic physical description. Different approaches and algorithms required to accomplish the future system are outlined. © 1974 ACM.

关键词： computer aided design

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