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Structural, optical, and thermal properties of BN thin films grown on diamond via pulsed laser deposition

Physical Review Materials 2023年第9期7卷 094602-094602页

作者： Abhijit Biswas Gustavo A. Alvarez Tao Li Joyce Christiansen-Salameh Eugene Jeong Anand B. Puthirath Sathvik Ajay Iyengar Chenxi Li Tia Gray Xiang Zhang Tymofii S. Pieshkov Harikishan Kannan Jacob Elkins Robert Vajtai A. Glen Birdwell Mahesh R. Neupane Elias J. Garratt Bradford B. Pate Tony G. Ivanov Yuji Zhao Zhiting Tian Pulickel M. Ajayan Department of Materials Science and Nanoengineering Rice University Houston Texas 77005 USA Sibley School of Mechanical and Aerospace Engineering Cornell University Ithaca New York 14853 USA Department of Electrical and Computer Engineering Rice University Houston Texas 77005 USA Applied Physics Graduate Program Smalley-Curl Institute Rice University Houston Texas 77005 USA DEVCOM Army Research Laboratory RF Devices and Circuits Adelphi Maryland 20783 USA Naval Research Laboratory Chemistry Division Washington District of Columbia 20375 USA

Heterostructures based on ultrawide-bandgap (UWBG) semiconductors (bandgap>4.0eV), such as BN and diamond, hold significant importance for the development of high-power electronics in the next generation. However, achieving in situ heteroepitaxy of BN/diamond or vice versa remains exceptionally challenging due to the complex growth kinetics involved. In this work, we grew BN thin film on (100) single-crystal diamonds using pulsed laser deposition and investigated its structural, magnetic, optical, and thermal properties. The structural analyses confirmed the growth of BN films, which exhibited diamagnetic behavior at room temperature. Notably, the film demonstrated anisotropic refractive index characteristics within the visible-to-near-infrared wavelength range. The room-temperature cross-plane thermal conductivity of BN is 1.53 ± 0.77 W/mK, while the thermal conductance of the BN/diamond interface is 20±2MW/m2K. These findings have significant implications for a range of device applications based on UWBG BN/diamond heterostructures.

关键词： Growth Thermal conductivity Boron nitride Thin films Wide band gap systems Film deposition Laser ablation Thermoreflectance

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Parameter-free differential evolution algorithm for the analytic continuation of imaginary time correlation functions

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Physical Review E 2022年第2期106卷 025312-025312页

作者： Nathan S. Nichols Paul Sokol Adrian Del Maestro Data Science and Learning Division Argonne National Laboratory Argonne Illinois 60439 USA Department of Physics University of Vermont Burlington Vermont 05405 USA Materials Science Program University of Vermont Burlington Vermont 05404 USA Department of Physics Indiana University Bloomington Indiana 47408 USA Department of Physics and Astronomy University of Tennessee Knoxville Tennessee 37996 USA Min H. Kao Department of Electrical Engineering and Computer Science University of Tennessee Knoxville Tennessee 37996 USA

We report on differential evolution for analytic continuation: a parameter-free evolutionary algorithm to generate the dynamic structure factor from imaginary time correlation functions. Our approach to this long-standing problem in quantum many-body physics achieves enhanced spectral fidelity while using fewer compute (CPU) hours. The need for fine-tuning of algorithmic control parameters is eliminated by embedding them within the genome to be optimized for this evolutionary computation-based algorithm. Benchmarks are presented for models where the dynamic structure factor is known exactly and experimentally relevant results are included for quantum Monte Carlo simulations of bulk He4 below the superfluid transition temperature.

关键词： Nonequilibrium statistical mechanics Helium-4 superfluids Genetic algorithm Neutron scattering Numerical techniques Path-integral Monte Carlo Quantum Monte Carlo

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Real-Time Cell Sorting with Scalable In Situ FPGA-Accelerated Deep Learning

arXiv

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arXiv 2025年

作者： Islam, Khayrul Forelli, Ryan F. Han, Jianzhong Bhadane, Deven Huang, Jian Agar, Joshua C. Tran, Nhan Ogrenci, Seda Liu, Yaling Department of Mechanical Engineering Lehigh University BethlehemPA18015 United States Department of Electrical and Computer Engineering Northwestern University EvanstonIL60208 United States Coriell Institute for Medical Research CamdenNJ United States Department of Computer Science Lehigh University BethlehemPA18015 United States Cooper Medical School of Rowan University CamdenNJ08103 United States Center for Metabolic Disease Research Temple University Lewis Katz School of Medicine PhiladelphiaPA19122 United States Department of Mechanical Engineering and Mechanics Drexel University PhiladelphiaPA19104 United States Real-time Processing Systems Division Fermi National Accelerator Laboratory BataviaIL60510 United States Department of Bioengineering Lehigh University BethlehemPA18015 United States

Precise cell classification is essential in biomedical diagnostics and therapeutic monitoring, particularly for identifying diverse cell types involved in various diseases. Traditional cell classification methods such as flow cytometry depend on molecular labeling which is often costly, time-intensive, and can alter cell integrity. To overcome these limitations, we present a label-free machine learning framework for cell classification, designed for real-time sorting applications using bright-field microscopy images. This approach leverages a teacher-student model architecture enhanced by knowledge distillation, achieving high efficiency and scalability across different cell types. Demonstrated through a use case of classifying lymphocyte subsets, our framework accurately classifies T4, T8, and B cell types with a dataset of 80,000 preprocessed images, accessible via an open-source Python package for easy adaptation. Our teacher model attained 98% accuracy in differentiating T4 cells from B cells and 93% accuracy in zero-shot classification between T8 and B cells. Remarkably, our student model operates with only 0.02% of the teacher model’s parameters, enabling field-programmable gate array (FPGA) deployment. Our FPGA-accelerated student model achieves an ultra-low inference latency of just 14.5 µs and a complete cell detection-to-sorting trigger time of 24.7 µs, delivering 12x and 40x improvements over the previous state-of-the-art real-time cell analysis algorithm in inference and total latency, respectively, while preserving accuracy comparable to the teacher model. This framework provides a scalable, cost-effective solution for lymphocyte classification, as well as a new SOTA real-time cell sorting implementation for rapid identification of subsets using in situ deep learning on off-the-shelf computing hardware. © 2025, CC BY.

关键词： Deep learning

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Strong nonreciprocal acoustic extinction and asymmetric audibility from spinning fluid scatterers

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Physical Review B 2023年第16期108卷 165129-165129页

作者： Yao-Ting Wang Heedong Goh Sander A. Mann Andrea Alù Photonics Initiative Advanced Science Research Center City University of New York New York New York 10031 USA Department of Photonics National Sun Yat-Sen University Kaohsiung 804201 Taiwan Department of Electrical and Computer Engineering The University of Texas at Austin Austin Texas 78712 USA Physics Program Graduate Center City University of New York New York New York 10026 USA

Lorentz reciprocity places important constraints on the response of systems to wave excitations, and surpassing these constraints is of both fundamental and applied interest. In the context of scattering, reciprocity requires that the total extinction of an object is identical when excited from opposite directions, regardless of the asymmetry of the scatterer. Here, we demonstrate that, by combining multiple scatterers that break time-reversal symmetry, this extinction symmetry can be largely violated. We consider spinning cylinders, demonstrating that nonreciprocity must be paired with broken parity symmetry to enable large extinction contrast. As a dramatic example, we show a system that strongly scatters when excited from one side, but it is cloaked for the opposite excitation. Our results pave the way for approaches to asymmetric audibility and scattering manipulation, and they may readily translate to other wave domains.

关键词： Acoustic metamaterials Acoustics Non-reciprocal propagation

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Novel diamond shuttle to deliver flexible neural probe with reduced tissue compression

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Microsystems & Nanoengineering 2020年第1期6卷 903-915页

作者： Kyounghwan Na Zachariah J.Sperry Jiaao Lu Mihaly Voroslakos Saman S.Parizi Tim M.Bruns Euisik Yoon John P.Seymour Electrical Engineering&Computer Science Department University of MichiganAnn ArborMI 48105USA Biomedical Engineering Department University of MichiganAnn ArborMI 48105USA Biointerfaces Institute University of MichiganAnn ArborMI 48105USA The Neuroscience Institute New York UniversityNew YorkNY 10016USA Center for Nanomedicine Institute for Basic Science(IBS)Seoul 03722Korea Graduate Program of Nano Biomedical Engineering(Nano BME) Yonsei-IBS InstituteYonsei UniversitySeoul 03722Korea Vivian L Smith Department of Neurosurgery University of Texas Health Science CenterHoustonTX 77030USA Department of Electrical and Computer Engineering Rice UniversityHoustonTX 77005USA

The ability to deliver flexible biosensors through the toughest membranes of the central and peripheral nervous system is an important challenge in neuroscience and neural *** devices implanted through dura mater and thick epineurium would ideally create minimal compression and acute damage as they reach the neurons of *** demonstrate that a three-dimensional diamond shuttle can be easily made with a vertical support to deliver ultra-compliant polymer microelectrodes(4.5-µm thick)through dura mater and thick *** diamond shuttle has 54%less cross-sectional area than an equivalently stiff silicon shuttle,which we simulated will result in a 37%reduction in blood vessel *** also discovered that higher frequency oscillation of the shuttle(200Hz)significantly reduced tissue compression regardless of the insertion speed,while slow speeds also independently reduced tissue *** and recording performance are demonstrated in rat and feline models,but the large design space of these tools are suitable for research in a variety of animal models and nervous system targets.

关键词： sectional neural thick

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Nonlocal Scatterer for Compact Wave-Based Analog Computing

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Physical Review Letters 2022年第7期128卷 073201-073201页

作者： Heedong Goh Andrea Alù Department of Electrical and Computer Engineering The University of Texas at Austin Austin Texas 78712 USA Photonics Initiative Advanced Science Research Center City University of New York New York New York 10031 USA Physics Program Graduate Center City University of New York New York New York 10016 USA

Analog computing based on wave interactions with metamaterials has been raising significant interest as a low-energy, ultrafast platform to process large amounts of data. Engineered materials can be tailored to impart mathematical operations of choice on the spatial distribution of the impinging signals, but they also require extended footprints and precise large-area fabrication, which may hinder their practical applicability. Here we show that the nonlocal response of a compact scatterer can be engineered to impart operations of choice on arbitrary impinging waves, and even to solve integro-differential equations, whose solution is observed in the scattered fields. The lack of strongly resonant phenomena makes the response robust, and the compact nature opens to scalability and cascading of these processes, paving the way to efficient, compact analog computers based on engineered microstructures.

关键词： Light propagation, transmission & absorption Mie scattering Scattering theory

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Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet)

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Journal of Cerebral Blood Flow and Metabolism 2024年第9期44卷 1480-1514页

作者： Kostoglou, Kyriaki Bello-Robles, Felipe Brassard, Patrice Chacon, Max Claassen, Jurgen AHR Czosnyka, Marek Elting, Jan-Willem Hu, Kun Labrecque, Lawrence Liu, Jia Marmarelis, Vasilis Z Payne, Stephen J Shin, Dae Cheol Simpson, David Smirl, Jonathan Panerai, Ronney B Mitsis, Georgios D Department of Electrical and Computer Engineering McGill University Montreal QC Canada Institute of Neural Engineering Graz University of Technology Graz Austria Departamento de Ingeniería Informática Universidad de Santiago de Chile Santiago Chile Department of Kinesiology Faculty of Medicine Université Laval QC Canada Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec Quebec QC Canada Department of Geriatrics Radboud University Medical Center Research Institute for Medical Innovation and Donders Institute Nijmegen Netherlands Cerebral Haemodynamics in Ageing and Stroke Medicine (CHiASM) Department of Cardiovascular Sciences University of Leicester Leicester United Kingdom Department of Clinical Neurosciences Neurosurgery Department University of Cambridge Cambridge United Kingdom Department of Neurology and Clinical Neurophysiology University Medical Center Groningen Groningen Netherlands Medical Biodynamics Program Division of Sleep and Circadian Disorders Brigham and Women's Hospital Harvard Medical School Boston MA United States Division of Sleep Medicine Harvard Medical School Boston MA United States Laboratory for Engineering and Scientific Computing Institute of Advanced Computing and Digital Engineering Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China Department Biomedical Engineering Viterbi School of Engineering University of Southern California Los Angeles CA United States Institute of Applied Mechanics National Taiwan University Taipei Taiwan Institute of Sound and Vibration Research University of Southampton Southampton United Kingdom Cerebrovascular Concussion Laboratory Faculty of Kinesiology University of Calgary Calgary AB Canada Sport Injury Prevention Research Centre Faculty of Kinesiology University of Calgary Calgary AB Canada Hotchkiss Brain Institute University of Calgary Calgary AB Canada NIHR Leicester Biomedical Research Centre Bri

Cerebral Autoregulation (CA) is an important physiological mechanism stabilizing cerebral blood flow (CBF) in response to changes in cerebral perfusion pressure (CPP). By maintaining an adequate, relatively constant supply of blood flow, CA plays a critical role in brain function. Quantifying CA under different physiological and pathological states is crucial for understanding its implications. This knowledge may serve as a foundation for informed clinical decision-making, particularly in cases where CA may become impaired. The quantification of CA functionality typically involves constructing models that capture the relationship between CPP (or arterial blood pressure) and experimental measures of CBF. Besides describing normal CA function, these models provide a means to detect possible deviations from the latter. In this context, a recent white paper from the Cerebrovascular Research Network focused on Transfer Function Analysis (TFA), which obtains frequency domain estimates of dynamic CA. In the present paper, we consider the use of time-domain techniques as an alternative approach. Due to their increased flexibility, time-domain methods enable the mitigation of measurement/physiological noise and the incorporation of nonlinearities and time variations in CA dynamics. Here, we provide practical recommendations and guidelines to support researchers and clinicians in effectively utilizing these techniques to study CA. © The Author(s) 2024.

关键词： CARNet cerebral autoregulation cerebral blood flow time-domain methods white paper

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Large-Scale Multidisciplinary Design Optimization of an eVTOL Aircraft Using Comprehensive Analysis

Large-Scale Multidisciplinary Design Optimization of an eVTO...

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AIAA SciTech Forum and Exposition, 2023

作者： Sarojini, Darshan Ruh, Marius L. Sperry, Mark Yan, Jiayao Fletcher, Andrew Joshy, Anugrah Jo Scotzniovsky, Luca Ivanov, Alexander Orndorff, Nicholas Gandarillas, Victor Asher, Isaac Chambers, Jeff Gill, Hyunjune Lee, Seongkyu Cheng, Zeyu Rodriguez, Gabriel Zhao, Shuofeng Mi, Chunting Nascenzi, Thomas Cuatt, Timothy Winter, Tyler Guibert, Alexandre Cronk, Ashley Kim, Alicia Meng, Shirley Hwang, John T. Department of Mechanical and Aerospace Engineering University of California San Diego 9500 Gilman Dr La Jolla CA92093 United States Flight Physics Aurora Flight Sciences A Boeing Company 9950 Wakeman Drive ManassasVA20110 United States Engineering Department Aurora Flight Sciences A Boeing Company 9950 Wakeman Drive ManassasVA20110 United States Department of Mechanical and Aerospace Engineering University of California Davis 1 Shields Avenue DavisCA95616 United States Department of Electrical and Computer Engineering San Diego State University 5500 Campanile Dr San Diego92182 United States Research and Development M4 Engineering Inc 4020 Long Beach Blvd # 2 Long BeachCA90807 United States Structural Engineering Department University of California San Diego 9500 Gilman Dr La Jolla CA92093 United States Materials Science and Engineering Program University of California San Diego 9500 Gilman Dr La Jolla CA92093 United States Department of NanoEngineering University of California San Diego 9500 Gilman Dr La Jolla CA92093 United States

ISBN: (数字)9781624106996

ISBN: (纸本)9781624106996

This paper presents a framework under development for enabling large-scale multi-fidelity modeling and optimization of electric vertical takeoff and landing concepts (eVTOL). The key features of the framework are a geometry-centric approach to multidisciplinary design optimization (MDO), a modular functional-form representation of the disciplines involved in aircraft design, and fully automated derivative computations thereby allowing efficient gradient-based optimization. The framework is first presented in a general manner agnostic to the vehicle concept or the physics-based analyses used. The key disciplines involved in the design of eVTOL aircraft and the couplings between the disciplines are described. The framework is then applied to the design of the NASA lift-plus-cruise concept. Low-fidelity solvers of aerodynamics, propulsion, structural estimation, acoustics, powertrain, and battery are coupled together. The optimization considers 108 design variables and 16 constraints. It is shown that MDO considering geometric variables results in a design with lower gross mass than when the geometric variables are not considered. The optimization turnaround time of 30 minutes on a standard workstation demonstrates the capabilities of fully-coupled large-scale MDO using gradient-based optimization. The framework is under development and an open-source version will be released in the near future. © 2023, American Institute of Aeronautics and Astronautics Inc, AIAA. All rights reserved.

关键词： Geometry

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UAS-Based Tools for Mapping and Monitoring Hydrothermal Systems: An Example from Mammoth Lakes, California

UAS-Based Tools for Mapping and Monitoring Hydrothermal Syst...

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2022 Geothermal Rising Conference: Using the Earth to Save the Earth, GRC 2022

作者： Zielinski, Laurie A. Glen, Jonathan M. Earney, Tait E. Rea-Downing, Grant H. Vaughan, R. Greg Kelly, Peter J. Keller, Gordon H. Dean, Branden J. Schermerhorn, William D. U.S. Geological Survey Geology Minerals Energy and Geophysics Science Center Moffett FieldCA United States University of Utah Department of Geology and Geophysics Salt Lake CityUT United States U.S. Geological Survey Astrogeology Science Center FlagstaffAZ United States U.S. Geological Survey Volcano Hazards Program VancouverWA United States University of California Santa Cruz Department of Electrical and Computer Engineering Santa CruzCA United States Mount Vernon WA United States

ISBN: (纸本)9781713871040

Unoccupied aerial systems (UAS) can accommodate a variety of tools for mapping and monitoring hydrothermal systems (e.g., magnetic, gas, photogrammetry, and thermal infrared [TIR]). These platforms offer increased speed, coverage area, and uniformity compared to ground-based measurements, as well as lower flight height - and therefore higher resolution - than occupied aircraft. We adapted a suite of tools for use with UAS and implemented these methods in a study focused on the area around Shady Rest Park, Mammoth Lakes, California, within the Long Valley Caldera. This location, which contains tree kills, gas vents, soil gas emissions, heated ground, and hydrothermal alteration, is the site of ongoing efforts to monitor changes in the surface expression of the local hydrothermal system. The methods applied in this study included: (1) airborne visible imagery for surficial mapping and the creation of high-resolution digital elevation models;(2) airborne magnetic measurements;(3) airborne TIR imagery;(4) airborne gas emission measurements;and (5) ground-based gravity measurements. We conducted these surveys in May and October of 2021, in part to establish baseline TIR and gas data against which future changes to the hydrothermal system may be assessed. UAS-based magnetic and ground-based gravity data were collected to map subsurface geology and to characterize potential subsurface controls on thermal anomalies and gas emissions. Results of these efforts at mapping and monitoring the hydrothermal system at Mammoth Lakes demonstrate how an integrated UAS- and ground-based approach may be applied more broadly to study other known or potential hydrothermal and volcanic systems. We consider the benefits and limitations of each method, particularly the TIR and gas sensors, which have less well-developed processing techniques in place for UAS applications. By integrating results from several of these different methods, however, the limitations facing each individual approach

关键词： Mapping

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The Role of Heterogeneity in Autonomous Perimeter Defense Problems

arXiv

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arXiv 2022年

作者： Adler, Aviv Mickelin, Oscar Ramachandran, K. Sukhatme, Gaurav S. Karaman, Sertac Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA United States Program in Applied and Computational Mathematics Princeton University Princeton NJ08544 United States Department of Computer Science University of Southern California Los AngelesCA90089 United States Department of Aeronautics and Astronautics Massachusetts Institute of Technology CambridgeMA02139 United States

When is heterogeneity in the composition of an autonomous robotic team beneficial and when is it detrimental? We investigate and answer this question in the context of a minimally viable model that examines the role of heterogeneous speeds in perimeter defense problems, where defenders share a total allocated speed budget. We consider two distinct problem settings and develop strategies based on dynamic programming and on local interaction rules. We present a theoretical analysis of both approaches and our results are extensively validated using simulations. Interestingly, our results demonstrate that the viability of heterogeneous teams depends on the amount of information available to the defenders. Moreover, our results suggest a universality property: across a wide range of problem parameters the optimal ratio of the speeds of the defenders remains nearly constant. Copyright © 2022, The Authors. All rights reserved.

关键词： Dynamic programming

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