We present a method of measuring the full susceptibility tensor map of samples using a modified high numerical aperture (NA) polarization sensitive optical coherence tomography (PS-OCT) system. This method promises hi...
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The design and fabrication of multi-layer amperometric electrochemical glucose sensors is dependent upon the diffusional kinetics of the chemical/biochemical species which contribute to the sensor's response. Cons...
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This paper reports a low-noise readout circuit for label-free, mobile detection of protein-ligand interactions. It is based on a new sensing technique where the surface charge of an electrode is altered due to the dip...
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This paper reports a low-noise readout circuit for label-free, mobile detection of protein-ligand interactions. It is based on a new sensing technique where the surface charge of an electrode is altered due to the dipole moment of nearby biomolecules. We propose a low-noise readout circuit to measure the sub-nA signals. Using a chopped low-noise integrating preamplifier and a resistive transimpedance amplifier, the gain of the proposed circuit is 1.7 GΩ with an input-referred noise of 82 fARMS over a 10 Hz bandwidth. We demonstrate that the designed amplifier can capture the induced molecular electronic signature of Trypsin with a 50×50 μm 2 sensing electrode.
A critical juncture in the undergraduate STEM education pathway is the first two years of college when the majority of attrition occurs because students experience many academic challenges in gatekeeping courses. Amon...
A critical juncture in the undergraduate STEM education pathway is the first two years of college when the majority of attrition occurs because students experience many academic challenges in gatekeeping courses. Among many factors to this failure, an important one is attributed to the lack of engaging pedagogy inside and outside classrooms. Through this NSF WIDER program sponsored planning project, a team of faculty and administrators at Alabama Agricultural and Mechanical University (AAMU) are implementing evidence-based instructional practices in foundation courses in STEM curricula. Recognizing that it is essential to implement effective pedagogy in gateway courses where most attrition occurs, this project has conducted a pilot study, which focuses on: (1) collecting baseline data about the extent to which evidence-based practices are currently being used in STEM gateway courses;(2) redesigning three foundational gateway courses in electricalengineering, computerscience and mathematics by applying evidence-based teaching strategies-student-centered problem-based teaching(SC-PBT), example-based teaching, and just-in-time teaching (JITT);(3) incorporating classroom and laboratory activities that require active student engagement, conceptual understanding, critical thinking, and problem-solving;and (4) Employing model students to lead Supplementary Instruction (SI) courses with evidence-based peer-to-peer learning strategies. The student assessment data indicated the effectiveness of the evidence-based instructional practices, the SI peer-to-peer learning strategies, as well as existing engagement challenges. In addition, positive feedback was obtained from the student survey data on the redesigned courses. The broader impact of this project is twofold. First, data generated through assessment and evaluation is expected to support the theoretical rationale that systematic change in STEM education must include a wide spectrum of stakeholders (administrators, facul
COnstraint-Based Reconstruction and Analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental data and quantitative prediction of physicochemically and biochemically feasible...
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We generate and reconstruct two-photon, 100-ps-separated time-bin-entangled qutrit states. By pairwise mapping time bins onto orthogonal polarizations, we perform a tomography and demonstrate high fidelity to maximall...
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We generate and reconstruct two-photon, 100-ps-separated time-bin-entangled qutrit states. By pairwise mapping time bins onto orthogonal polarizations, we perform a tomography and demonstrate high fidelity to maximally entangled qutrit states.
Sand production in petroleum wells is a major concern for the petroleum industry. Sand production results in erosion of pipelines and damage to equipment which may lead to production shutdown and large economic losses...
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ISBN:
(纸本)9781479961153
Sand production in petroleum wells is a major concern for the petroleum industry. Sand production results in erosion of pipelines and damage to equipment which may lead to production shutdown and large economic losses. Detection of produced sand is important for optimizing flow rates and measuring the success of sand mitigation techniques. Recently, microwave nondestructive testing was considered as a potential new sensing solution for the detection of sand production. This paper presents preliminary simulations and measurements for such a sensing approach using open-ended waveguides. Different production scenarios are considered for a stratified flow regime. The results indicate that this sensing method can detect the presence of sand. Preliminary measurements are also presented for varying amounts of sand that further support the potential of this technique.
In the version of the article published, the author list is not accurate. Igor Cima and Min-Han Tan should have been authors, appearing after Mark Wong in the author list, while Paul Jongjoon Choi should not have been...
In the version of the article published, the author list is not accurate. Igor Cima and Min-Han Tan should have been authors, appearing after Mark Wong in the author list, while Paul Jongjoon Choi should not have been listed as an author. Igor Cima and Min-Han Tan both have the affiliation Institute of bioengineering and Nanotechnology, Singapore, Singapore, and their contributions should have been noted in the Author Contributions section as "I.C. preprocessed Primary Cell Atlas data with inputs from M.-H.T." The following description of the contribution of Paul Jongjoon Choi should not have appeared: "P.J.C. supported the smFISH experiments." In the 'RCA: global panel' section of the Online Methods, the following sentence should have appeared as the second sentence, "An expression atlas of human primary cells (the Primary Cell Atlas) was preprocessed similarly to in ref. 55," with new reference 55 (Cima, I. et al. Tumor-derived circulating endothelial cell clusters in colorectal cancer. science Transl. Med. 8, 345ra89, 2016).
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