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Current-driven homogenization and effective medium parameters for finite samples

Physical Review B 2013年第12期88卷 125131-125131页

作者： Vadim A. Markel Igor Tsukerman Departments of Radiology and Bioengineering and the Graduate Group in Applied Mathematics and Computational Science University of Pennsylvania Philadelphia Pennsylvania 19104 USA Department of Electrical and Computer Engineering The University of Akron Ohio 44325-3904 USA

Reflection and refraction of electromagnetic waves by artificial periodic composites (metamaterials) can be accurately modeled by an effective medium theory only if the boundary of the medium is explicitly taken into account and the two effective parameters of the medium (the index of refraction and the impedance) are correctly determined. Theories that consider infinite periodic composites do not satisfy the above condition. As a result, they can not model reflection and transmission by finite samples with the desired accuracy and are not useful for design of metamaterial-based devices. As an instructive case in point, we consider the “current-driven” homogenization theory, which has recently gained popularity. We apply this theory to the case of one-dimensional periodic medium wherein both exact and homogenization results can be obtained analytically in closed form. We show that, beyond the well-understood zero-cell limit, the current-driven homogenization result is inconsistent with the exact reflection and transmission characteristics of the slab.

关键词： ELECTROMAGNETISM MAGNETIC fields METAMATERIALS MAGNETOELECTRIC effect REFRACTION (Optics)

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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Periodic dynamics, localization metastability, and elastic interaction of colloidal particles with confining surfaces and helicoidal structure of cholesteric liquid crystals

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Physical Review E 2014年第6期90卷 062502-062502页

作者： Michael C. M. Varney Qiaoxuan Zhang Mykola Tasinkevych Nuno M. Silvestre Kris A. Bertness Ivan I. Smalyukh Department of Physics University of Colorado at Boulder Boulder Colorado 80309 USA Materials Science and Engineering Program University of Colorado at Boulder Boulder Colorado 80309 USA Max-Planck-Institut für Intelligente Systeme D-70569 Stuttgart Germany Institut für Theoretische Physik IV Universität Stuttgart D-70569 Stuttgart Germany Centro de Física Teórica e Computacional and Faculdade de Ciências da Universidade de Lisboa Av. Prof. Gama Pinto 2 1649-003 Lisboa Portugal National Institute of Standards and Technology Boulder Colorado 80305 USA Department of Electrical Computer and Energy Engineering and Liquid Crystals Materials Research Center University of Colorado at Boulder Boulder Colorado 80309 USA Renewable and Sustainable Energy Institute National Renewable Energy Laboratory and University of Colorado at Boulder Boulder Colorado 80309 USA

Nematic and cholesteric liquid crystals are three-dimensional fluids that possess long-range orientational ordering and can support both topological defects and chiral superstructures. Implications of this ordering remain unexplored even for simple dynamic processes such as the ones found in so-called “fall experiments,” or motion of a spherical inclusion under the effects of gravity. Here we show that elastic and surface anchoring interactions prompt periodic dynamics of colloidal microparticles in confined cholesterics when gravity acts along the helical axis. We explore elastic interactions between colloidal microparticles and confining surfaces as well as with an aligned ground-state helical structure of cholesterics for different sizes of spheres relative to the cholesteric pitch, demonstrating unexpected departures from Stokes-like behavior at very low Reynolds numbers. We characterize metastable localization of microspheres under the effects of elastic and surface anchoring periodic potential landscapes seen by moving spheres, demonstrating the important roles played by anchoring memory, confinement, and topological defect transformation. These experimental findings are consistent with the results of numerical modeling performed through minimizing the total free energy due to colloidal inclusions at different locations along the helical axis and with respect to the confining substrates. A potential application emerging from this work is colloidal sorting based on particle shapes and sizes.

关键词： CHOLESTERIC liquid crystals LIQUID crystals ENANTIOSELECTIVE catalysis HELICAL waveguides GRAVITY

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Gradient field microscopy for label-free diagnosis of human biopsies [Invited]

Gradient field microscopy for label-free diagnosis of human ...

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作者： Kim, Taewoo Sridharan, Shamira Kajdacsy-Balla, André Tangella, Krishnarao Popescu, Gabriel Quantitative Light Imaging Laboratory Department of Electrical and Computer Engineering Beckman Institute for Advanced Science and Technology Urbana IL 61801 United States Quantitative Light Imaging Laboratory Department of Bioengineering Beckman Institute for Advanced Science and Technology Urbana IL 61801 United States University of Illinois at Chicago Department of Pathology Chicago IL 60612 United States Christie Clinic Department of Pathology University of Illinois at Urbana-Champaign Urbana IL 61801 United States

We introduce a label-free method for detecting high-grade prostatic intraepithelial neoplasia (HGPIN) in unstained biopsies. We image this condition based on the identification of basal cells in biopsies that otherwise would resemble prostate cancer by unassisted histologic examination. Gradient field microscopy (GFM) is used as a label-free imaging method which increases the contrast of a transparent sample by taking the first-order phase derivative that is very sensitive to rapid refractive index changes. GFM is able to image the basal cell layers in HGPIN biopsies because of their rapid refractive index changes at the periphery of small glandular structures. © 2012 Optical Society of America.

关键词： Biopsy

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Recent Advances in Detection of Ochratoxin-A

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Open Journal of Applied Biosensor 2013年第1期2卷 1-11页

作者： Ajeet Kaushik Sunil K. Arya Abhay Vasudev Shekhar Bhansali Bioelectronics Program Institute of Microelectronics A*STAR (Agency for Science Technology and Research) 11 Science Park Road Singapore Science Park II Singapore 117685 Singapore Bio-MEMS and Microsystems Lab Department of Electrical and Computer Engineering Florida International University Miami USA Bio-MEMS and Microsystems Lab Department of Electrical and Computer EngineeringFlorida International University Miami USA Department of Biomedical Engineering Florida International University Miami USA

Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.

关键词： Biopolymer Mycotoxins Ochratoxin-A Chitosan Organic-Inorganic Hybrid Nanocomposite Biosensors

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Steep subthreshold slope nanowire nanoelectromechanical field-effect transistors (NW-NEMFETs)

Steep subthreshold slope nanowire nanoelectromechanical fiel...

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Berkeley Symposium on Energy Efficient Electronic Systems (E3S)

作者： Ji-Hun Kim Zack C. Y. Chen Soonshin Kwon Jie Xiang Department of Electrical and Computer Engineering University of California San La Jolla CA Department of Materials Science Program University of California San La Jolla CA

Significant physical challenges remain for CMOS technology to decrease I off as transistor dimension and power supply voltages continue downscaling. However, a fundamental thermodynamic limit in the subthreshold slope SS = |(∂V g )/(∂lnI d )| = ln10 · k B T/q at >60 mV/dec exists at room temperature. We have designed and demonstrated the first semiconductor nanowires (NWs) and nanoelectromechanical system (NEMS) field effect transistor structure (NW-NEMFET). We have previously demonstrated 0.5 ps intrinsic delay and near ballistic operation in quantum confined semiconductor heterostructure NWFETs with diameters less than 15 nm.[1] The current design uses high performance suspended semiconductor NWs as the conduction channel, while the electrostatic pull-in of the NW towards the gate stack enables abrupt switching to the off-state leading to high frequency, low power nanoelectronics. Simulation shows that compared to planar suspended-gate FET (SGFET) design [2], NW-NEMFET allows zero SS with 10 15 on-off ratio and near 1V pull-in voltage due to enhanced 3D capacitive coupling, as well as operation at very-high-frequency (VHF) and even ultra-high-frequency (UHF) due to the NW beams high aspect ratio and small dimensions.

关键词： Logic gates Silicon Electrodes Couplings Electrostatics Three-dimensional displays Transistors

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Multi-hole defect photonic crystals with enhanced surface area for biosensing applications

Multi-hole defect photonic crystals with enhanced surface ar...

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Laser science, LS 2013

作者： Hu, S. Kang, C. Zhao, Y. Mares, J.W. Vlasov, Y.A. Assefa, S. Weiss, S.M. Department of Physics and Astronomy Vanderbilt University Nashville TN 37235 United States Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN 37235 United States IBM T.J. Watson Research Center Yorktown Heights NY 10536 United States

Multi-hole defect (MHD) photonic crystal cavities functionalized with in situ synthesized DNA bioreceptors are demonstrated for biosensing applications. By significantly increasing light interaction with target biomol... 详细信息

ISBN: (纸本)9781557529879

关键词： Photonic crystals

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Group Method of Data Handling for Modeling Magnetorheological Dampers

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Intelligent Control and Automation 2013年第1期4卷 70-79页

作者： Khaled Assaleh Tamer Shanableh Yasmin Abu Kheil Department of Computer Science and Engineering American University of Sharjah Sharjah United Arab Emirates Department of Electrical Engineering American University of Sharjah Sharjah United Arab Emirates Mechatronics Graduate Program American University of Sharjah Sharjah United Arab Emirates

This paper proposes the use of Group Method of Data Handling (GMDH) technique for modeling Magneto-Rheological (MR) dampers in the context of system identification. GMDH is a multilayer network of quadratic neurons that offers an effective solution to modeling non-linear systems. As such, we propose the use of GMDH to approximate the forward and inverse dynamic behaviors of MR dampers. We also introduce two enhanced GMDH-based solutions. Firstly, a two-tier architecture is proposed whereby an enhanced GMD model is generated by the aid of a feedback scheme. Secondly, stepwise regression is used as a feature selection method prior to GMDH modeling. The proposed enhancements to GMDH are found to offer improved prediction results in terms of reducing the root-mean-squared error by around 40%.

关键词： System Identification Magneto-Rheological Dampers Group Method of Data Handling Polynomial Classifier

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High Energy Density, High Operating Frequency and Energy Efficient On-Chip Inductors based on Coiled Carbon Nanotubes (CCNTs)

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MRS Online Proceedings Library (OPL) 2013年第1期1551卷 41-46页

作者： H. Faraby P. R. Bandaru Department of Electrical and Computer Engineering University of California San Diego La Jolla California 92093-0407 USA Department of Mechanical and Aerospace Engineering Materials Science Program University of California San Diego La Jolla California 92093-0411 USA

We demonstrate the superior inductive properties of coiled carbon nanotubes (CCNTs) through numerical computation and analytical modeling, for the next generation of nanoscale, on-chip inductors. Taking advantage of the kinetic inductance (Lk), particularly evident at the nanoscale we find that the inductance can be increased by three orders of magnitude through changing the tube radius as well as the coil radius while the device footprint of the CCNTs can be reduced by 60%. By varying the geometric parameters of the coiled structure, the external magnetic inductance (LM,ext) can be as high as 20% of the Lk. We also report that the self resonant frequency (fSR) of CCNTs can be as much of the order of THz whereas the fSR of conventional copper(Cu) spiral inductors are limited to around 40GHz. Moreover when the material volume is considered, CCNTs have the potential to achieve Quality Factor (Q) eight times as Cu and when the footprint volume is considered Q can be twice as Cu All these promising properties of CCNTs make them a potential candidate for the entire frequency spectrum.

关键词： C nanoscale morphology

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Low-power signal processing methodologies for implantable biosensing platforms

Low-power signal processing methodologies for implantable bi...

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IEEE Signal Processing in Medicine and Biology Symposium (SPMB)

作者： Robert A. Croce Santhisagar Vaddiraju Allen Legassey Syed K. Islam Fotios Papadimitrakopoulos Faquir C. Jain Department of Electrical and Computer Engineering University of Connecticut CT USA Dept. of Chemistry University of Connecticut CT USA Technology Incubation Program Biorasis Inc. CT USA Department of Electrical Engineering and Computer Science University of Tennessee Knoxville TN USA

This paper presents the design and implementation of highly-miniaturized, low-power CMOS signal conditioning schemes intended for use in a totally implantable biomedical sensor platform. Due to the thrust for the development implantable biomedical sensing systems for health management and disease prevention, there exists a need for signal processing schemes which occupy very little on-chip real estate and consume negligible amounts of power. In light of this, this paper presents both a CMOS current-to-frequency converter and voltage-to-frequency converter which have been designed primarily for use in implantable biosensing platforms and applications. Such designs can be implemented in stand-alone single sensor designs, or in tandem to create multi-analyte architectures. The versatility of employing current-to-frequency as well as voltage-to-frequency signal transduction schemes presents an avenue for the integration with any electrochemical sensing element which has been fabricated in an amperometric or voltammetric fashion. Furthermore, we demonstrate the efficacy of both these circuit designs by integrating them together with high performance electrochemical implantable glucose and pH sensors. The low power consumption and miniature size of the amperometric and voltammetric signal processing units (0.25 mm 2 and 18 μW / 0.045 mm 2 and 122 μW, respectively) presents an ideal design for signal processing in implantable continuous metabolic monitoring devices.

关键词： Monitoring Biomedical monitoring Educational institutions CMOS integrated circuits Microelectronics Current measurement Sugar

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