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TechRxiv 2023年

作者： Albin, Dreycey Buecherl, Lukas Kochavi, Eitan Niehaus, Elise Novack, Sasha Uragoda, Shenali Myers, Chris J. Alistar, Mirela Department of Computer Science CU Boulder BoulderCO United States Biomedical Engineering Program CU Boulder United States Department of Electrical Computer and Energy Engineering and Biomedical Engineering Program CU Boulder United States ATLAS Institute The Department of Computer Science CU Boulder BoulderCO United States

Objective: Recent advancements demonstrate the significant role of digital microfluidics in automating laboratory work with DNA and on-site viral testing. However, since commercially available instruments are limited to droplet manipulation, our work addresses the need for accelerated integration of other components, such as temperature control, that can expand the application domain. Methods: We developed PhageBox— an accessible device that can be used as a biochip extension. At hardware level, PhageBox integrates temperature and electromagnetic control modules. At software level, PhageBox is controlled by embedded software containing a unique model for bio-protocol programming, and a graphical user interface for visual device feedback and operation. Results: To evaluate PhageBox’s efficacy for biomedical applications, we performed functional testing. Similarly, we validated the temperature control using thermography, obtaining a range of ±0.2◦C. The electromagnets produced a magnetic force of 15 milliTesla, demonstrating precise immobilization of magnetic beads. We show the potential of PhageBox for bacteriophage research through three initial protocols: a universal framework for PCR, T7 bacteriophage restriction enzyme digestion, and concentrating X174 RF genomic DNA. Conclusion: Our work presents an open-source hardware and software extension for digital microfluidics devices. This extension integrates temperature and electromagnetic modules, demonstrating efficacy in biomedical applications and potential for bacteriophage research. Significance: We developed PhageBox to be accessible: the components are off-the-shelf at a low cost (≤$200), and the hardware designs and software code are open-source. With the long aim of ensuring reproducibility and accelerating collaboration, we also provide a DIY-build document. (GitHub: https://***/Dreycey/PhageBox) © 2023, CC BY-SA.

关键词： Digital microfluidics

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High-Resolution Hydrogen Molecule Detection Utilizing a Nanocandle-Based Optical Sensor 16

High-Resolution Hydrogen Molecule Detection Utilizing a Nano...

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16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Park, Nu-Ri Kim, Min-Joong Lee, Jongsu Seo, Minah Ryu, Yong-Sang Kim, Myung-Ki KU-KIST Graduate School of Converging Science and Technology Korea University Seoul02841 Korea Republic of Korea Institute of Science and Technology Sensor System Research Center Seoul02792 Korea Republic of Northwestern University Department of Electrical Engineering and Computer Science EvanstonIL60208 United States School of Biomedical Engineering Korea University Seoul02481 Korea Republic of Interdisciplinary Program in Precision Public Health Korea University Seoul02481 Korea Republic of

Our research introduces a novel method for safe hydrogen detection. We've developed an advanced nano-candle sensor, combining Pd with nano-candles, enabling accurate detection of low-concentration hydrogen ( ©... 详细信息

ISBN: (纸本)9798350372076

关键词： Nanoclay

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Characteristic Mode Analysis of Nanostructures using Hydrodynamic Volume Integral Equation

Characteristic Mode Analysis of Nanostructures using Hydrody...

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Antennas and Propagation & USNC/URSI National Radio science Meeting

作者： Meruyert Khamitova Ran Zhao Doolos Aibek uulu Hakan Bagci Electrical and Computer Engineering (ECE) Program Computer Electrical and Mathematical Science and Engineering (CEMSE) Division King Abdullah University of Science and Technology (KAUST) Thuwal Kingdom of Saudi Arabia School of Electronic Science and Engineering University of Electronic Science and Technology of China (UESTC) Chengdu Sichuan China Department of Mathematics and Natural Sciences University of Central Asia (UCA) Naryn Kyrgyzstan

ISBN: (数字)9798350369908

ISBN: (纸本)9798350369915

The characteristic mode analysis (CMA) is formulated and implemented for the hydrodynamic volume integral equation (HDVIE) that is used to mathematically model electromagnetic field interactions and conduction current dynamics on nanoantennas and nanoscatterers. The proposed method produces excitation-independent characteristic hydrodynamic currents and the corresponding modal significance curves, providing useful information that can be used to optimize the performance of a nanoantenna. Numerical results demonstrate the reliability and the applicability of the proposed approach.

关键词： Solid modeling Nanoantennas Integral equations Hydrodynamics Mathematical models Characteristic mode analysis Numerical models

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Terahertz Time-Domain Imaging for Radiotherapy Treatment Monitoring in Pancreatic Ductal Adenocarcinoma

Terahertz Time-Domain Imaging for Radiotherapy Treatment Mon...

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CLEO: Applications and Technology in CLEO 2024, CLEO: A and T 2024 - Part of Conference on Lasers and Electro-Optics

作者： Chakraborty, Debamitra Mills, Bradley N. Cheng, Jing Komissarov, Ivan Gerber, Scott Sobolewski, Roman Materials Science Graduate Program University of Rochester RochesterNY14627 United States Laboratory for Laser Energetics University of Rochester RochesterNY14623-1299 United States Department of Surgery University of Rochester Medical Center RochesterNY14642 United States Department of Electrical and Computer Engineering University of Rochester RochesterNY14627-0231 United States

ISBN: (纸本)9781957171395

Terahertz time-domain imaging was performed of stereotactic body radiotherapy-treated murine pancreatic ductal adenocarcinoma (PDAC) with a high spatial resolution. To generate 2D maps of the tissue samples, the refractive index and absorption coefficient were used as imaging markers extracted with the maximum a-posteriori probability (MAP) estimation algorithm. The results were then compared with the terahertz maps of untreated murine PDAC tissue samples and demonstrated that terahertz imaging can probe physical changes with high sensitivity in the tissue post treatment. © Optica Publishing Group 2024, © 2024 The Author(s)

关键词： Tissue

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Neural network uncertainty quantification in inverse imaging problems using cycle consistency

Neural network uncertainty quantification in inverse imaging...

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CLEO: Applications and Technology in CLEO 2024, CLEO: A and T 2024 - Part of Conference on Lasers and Electro-Optics

作者： Huang, Luzhe Li, Jianing Ding, Xiaofu Zhang, Yijie Chen, Hanlong Ozcan, Aydogan Electrical and Computer Engineering Department University of California Los AngelesCA90095 United States Bioengineering Department University of California Los AngelesCA90095 United States University of California Los AngelesCA90095 United States Computer Science Department University of California Los AngelesCA90095 United States Department of Mathematics University of California Los AngelesCA90095 United States David Geffen School of Medicine University of California Los Angeles Los AngelesCA90095 United States

We present an uncertainty quantification method for neural networks solving inverse imaging problems. We leverage the physical forward model to establish forward-backward cycles to quantify inference uncertainty and detect out-of-distribution data in computational imaging tasks. © Optica Publishing Group 2024, © 2024 The Author(s)

关键词： Neural network models

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Minimization of fanout in switching networks 15

Minimization of fanout in switching networks

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15th Annual Symposium on Switching and Automata Theory, SWAT 1974

作者： Hayes, John P. Department of Electrical Engineering and Computer Science Program University of Southern California Los AngelesCA90007 United States

The problem of finding the minimum amount of fanout needed to realize a switching function f is investigated. Fanout-free functions are defined, and necessary and sufficient conditions for a function to be fanout-free are derived. A measure '(f) called the input fanout index, is introduced which represents the minimum number of input variables that fan out in any realization of f. I is shown that t(f), can be determined from the prime implicants and implicates of f. Another measure of fanout u(f), which is the minimum numbe r of signal lines that must fan out in any network realizing f is defined, and some of the properties of u(f) are examined. © 2021 IEEE. All rights reserved.

关键词： Switching networks

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Lightweight Pedestrian Detection through Guided Filtering and Deep Learning 10

Lightweight Pedestrian Detection through Guided Filtering an...

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10th IEEE Global Conference on Consumer Electronics, GCCE 2021

作者： Muchtar, Kahlil Saddami, Khairun Bintang, Akhyar Cenggoro, Tjeng Wawan Pardamean, Bens Lin, Chih-Yang Ernita, Tia Universitas Syiah Kuala Department of Electrical And Computer Engineering Aceh Indonesia Universitas Syiah Kuala Department of Electrical And Computer Engineering Aceh Indonesia Bina Nusantara University School of Computer Science Bina Nusantara University Bioinformatics And Data Science Research Center Computer Science Department Jakarta Indonesia Bina Nusantara University BINUS Graduate Program-Master of Computer Science Program Bina Nusantara University Bioinformatics And Data Science Research Center Computer Science Department Jakarta Indonesia Yuan-Ze University Department of Electrical And Engineering Taoyuan Taiwan

ISBN: (纸本)9781665436762

In this paper, we propose a novel approach to locate and detect moving pedestrians in a video. Our proposed method first locates the region of interest (ROI) using a background subtraction algorithm based on guided filtering. This novel background subtraction algorithm allows our method to also filter unexpected noises at the same time, which could benefit the performance of our proposed method. Subsequently, the pedestrians are detected using YOLOv3 within the provided ROI. Our experiments showed that the proposed method has a competitive performance in the CDNET2014 dataset with a fast-processing time. © 2021 IEEE.

关键词： Convolutional neural networks

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Digital Technology in Health Education Trend Mapping through Bibliometrics Analysis 4

Digital Technology in Health Education Trend Mapping through...

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4th International Conference on Informatics, Multimedia, Cyber and Information System, ICIMCIS 2022

作者： Maulana, Fairuz Iqbal Lestari, Dian Widartha, Vandha Pradwiyasma Haidar, Nirwana Dirgantara, Wahyu School of Computer Science Bina Nusantara University Computer Science Department Jakarta11480 Indonesia Airlangga University Faculty of Medicine Surabaya60132 Indonesia Telkom University Information System of Industrial Engineering Faculty Bandung Indonesia University of Madura Informatics Engineering Study Program Pamekasan Indonesia University of Merdeka Malang Department of Electrical Engineering Malang Indonesia

ISBN: (纸本)9781665473279

This study examines the mapping of research data on digital technology in the field of health education using bibliometric analysis method. Data was collected by identifying keywords in the Scopus database and sorting them out to sort the studies from the last 10 years (2012-2021). Through this step, a total of 1482 documents were obtained (articles, journals, proceedings, books, and others). The data is then processed using the VOSViewer instrument to obtain a visualization of the mapping analysis. This study also analyzes the network types of authors and co-authors through the VOSViewer instrument. The result of this study indicates that the most document types published within ten years are Articles (66.5%), Review (22.9%), Conference Paper (4.2%), and others. The most studied subjects are Medicine (55.7%), Nursing (9.0%), Health Professions (8.2%), Social sciences (7.8%), engineering (3.9%), computer science (2.6%), Environmental science (2.6%), Biochemistry-Genetics and Molecular Biology (2.2%), Psychology (1.6%), and Dentistry (1.3%). This study offers a written communication process and the nature and direction of developing descriptive means of counting and analyzing the various phases of communication as well as recognizing the authorship and direction of its symptoms in documents on the subject of digital technology in the health sector. © 2022 IEEE.

关键词： Mapping

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Modular Self-Lock Origami: design, modeling, and simulation to improve the performance of a rotational joint

arXiv

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arXiv 2023年

作者： Zare, Samira Spaeth, Alex Suresh, Sandya Teodorescu, Mircea Department of Electrical and Computer Engineering University of California Santa Cruz United States SIP program University of California Santa Cruz United States Department of Computer Science and Engineering United States

Origami structures have been widely explored in robotics due to their many potential advantages. Origami robots can be very compact, as well as cheap and efficient to produce. In particular, they can be constructed in a flat format using modern manufacturing techniques. Rotational motion is essential for robotics, and a variety of origami rotational joints have been proposed in the literature. However, few of these are even approximately flat-foldable. One potential enabler of flat origami rotational joints is the inclusion of lightweight pneumatic pouches which actuate the origami’s folds;however, pouch actuators only enable a relatively small amount of rotational displacement. The previously proposed Four-Vertex Origami is a flat-foldable structure which provides an angular multiplier for a pouch actuator, but suffers from a degenerate state. This paper presents a novel rigid origami, the Self-Lock Origami, which eliminates this degeneracy by slightly relaxing the assumption of flat-foldability. This joint is analysed in terms of a trade-off between the angular multiplier and the mechanical advantage. Furthermore, the Self-Lock Origami is a modular joint which can be connected to similar or different joints to produce complex movements for various applications;three different manipulator designs are introduced as a proof of concept. Copyright © 2023, The Authors. All rights reserved.

关键词： Manipulators

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The Impact of SBOM Generators on Vulnerability Assessment in Python: A Comparison and a Novel Approach

arXiv

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arXiv 2024年

作者： Benedetti, Giacomo Cofano, Serena Brighente, Alessandro Conti, Mauro Department of Informatics Bioengineering Robotics and Systems Engineering University of Genoa Italy IMT School for Advanced Studies Lucca Italy Department of Mathematics University of Padua Italy Faculty of Electrical Engineering Mathematics and Computer Science Delft University of Technology Netherlands

The Software Supply Chain (SSC) security is a critical concern for both users and developers. Recent incidents, like the SolarWinds Orion compromise, proved the widespread impact resulting from the distribution of compromised software. The reliance on open-source components, which constitute a significant portion of modern software, further exacerbates this risk. To enhance SSC security, the Software Bill of Materials (SBOM) has been promoted as a tool to increase transparency and verifiability in software composition. However, despite its promise, SBOMs are not without limitations. Current SBOM generation tools often suffer from inaccuracies in identifying components and dependencies, leading to the creation of erroneous or incomplete representations of the SSC. Despite existing studies exposing these limitations, their impact on the vulnerability detection capabilities of security tools is still unknown. In this paper, we perform the first security analysis on the vulnerability detection capabilities of tools receiving SBOMs as input. We comprehensively evaluate SBOM generation tools by providing their outputs to vulnerability identification software. Based on our results, we identify the root causes of these tools' ineffectiveness and propose PIP-sbom, a novel pip-inspired solution that addresses their shortcomings. PIP-sbom provides improved accuracy in component identification and dependency resolution. Compared to best-performing state-of-the-art tools, PIP-sbom increases the average precision and recall by 60%, and reduces by ten times the number of false positives. © 2024, CC BY-SA.

关键词： Input output programs

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