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arXiv 2020年

作者： Marcote, B. Nimmo, K. Hessels, J.W.T. Tendulkar, S.P. Bassa, C.G. Paragi, Z. Keimpema, A. Bhardwaj, M. Karuppusamy, R. Kaspi, V.M. Law, C.J. Michilli, D. Aggarwal, K. Andersen, B. Archibald, A.M. Bandura, K. Bower, G.C. Boyle, P.J. Brar, C. Burke-Spolaor, S. Butler, B.J. Cassanelli, T. Chawla, P. Demorest, P. Dobbs, M. Fonseca, E. Giri, U. Good, D.C. Gourdji, K. Josephy, A. Kirichenko, A.Yu. Kirsten, F. Landecker, T.L. Lang, D. Lazio, T.J.W. Li, D.Z. Lin, H.-H. Linford, J.D. Masui, K. Mena-Parra, J. Naidu, A. Ng, C. Patel, C. Pen, U.-L. Pleunis, Z. Rafiei-Ravandi, M. Rahman, M. Renard, A. Scholz, P. Siegel, S.R. Smith, K.M. Stairs, I.H. Vanderlinde, K. Zwaniga, A.V. Oude Hoogeveensedijk 4 PD Dwingeloo7991 Netherlands ASTRON Netherlands Institute for Radio Astronomy Oude Hoogeveensedijk 4 PD Dwingeloo7991 Netherlands Anton Pannekoek Institute for Astronomy University of Amsterdam Science Park 904 Amsterdam1098 XH Netherlands Department of Physics McGill University 3600 University Street MontréalQCH3A 2T8 Canada McGill Space Institute McGill University 3550 University Street MontréalQCH3A 2A7 Canada Max-Planck-Institut für Radioastronomie Auf dem Hügel 69 BonnD-53121 Germany Department of Astronomy and Owens Valley Radio Observatory California Institute of Technology PasadenaCA91125 United States Department of Physics and Astronomy West Virginia University P.O. Box 6315 MorgantownWV26506 United States Center for Gravitational Waves and Cosmology West Virginia University Chestnut Ridge Research Building MorgantownWV26505 United States School of Mathematics Physics and Statistics University of Newcastle Newcatle upon TyneNE1 7RU United Kingdom Lane Department of Computer Science and Electrical Engineering MorgantownWV26506 United States Academia Sinica Institute of Astronomy and Astrophysics 645 N. A’ohoku Place HiloHI96720 United States National Radio Astronomy Observatory SocorroNM87801 United States Dunlap Institute for Astronomy & Astrophysics University of Toronto 50 St. George Street TorontoONM5S 3H4 Canada Department of Astronomy & Astrophysics University of Toronto 50 St. George Street TorontoONM5S 3H4 Canada Perimeter Institute for Theoretical Physics WaterlooONN2L 2Y5 Canada Department of Physics and Astronomy University of Waterloo WaterlooONN2L 3G1 Canada Department of Physics and Astronomy University of British Columbia 6224 Agricultural Road VancouverBCV6T 1Z1 Canada Instituto de Astronomía Universidad Nacional Autónoma de México Apdo. Postal 877 EnsenadaBaja California22800 Mexico Ioffe Institute 26 Politekhnicheskaya st. St. Petersburg194021 Russia Department o

Fast radio bursts (FRBs) are brief, bright, extragalactic radio flashes1, 2. Their physical origin remains unknown, but dozens of possible models have been postulated3. Some FRB sources exhibit repeat bursts4–7. Though over a hundred FRB sources have been discovered to date8, only four have been localised and associated with a host galaxy9–12, with just one of the four known to repeat9. The properties of the host galaxies, and the local environments of FRBs, provide important clues about their physical origins. However, the first known repeating FRB has been localised to a low-metallicity, irregular dwarf galaxy, and the apparently non-repeating sources to higher-metallicity, massive elliptical or star-forming galaxies, suggesting that perhaps the repeating and apparently non-repeating sources could have distinct physical origins. Here we report the precise localisation of a second repeating FRB source6, FRB 180916.J0158+65, to a star-forming region in a nearby (redshift z = 0.0337 ±0.0002) massive spiral galaxy, whose properties and proximity distinguish it from all known hosts. The lack of both a comparably luminous persistent radio counterpart and a high Faraday rotation measure6 further distinguish the local environment of FRB 180916.J0158+65 from that of the one previously localised repeating FRB source, FRB 121102. This demonstrates that repeating FRBs have a wide range of luminosities, and originate from diverse host galaxies and local environments. Copyright © 2020, The Authors. All rights reserved.

关键词： Galaxies

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LifeTime and improving European healthcare through cell-based interceptive medicine (vol 587, pg 377, 2020)

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NATURE 2021年第7852期592卷 E8-E8页

作者： Rajewsky, Nikolaus Almouzni, Genevieve Gorski, Stanislaw A. Aerts, Stein Amit, Ido Bertero, Michela G. Bock, Christoph Bredenoord, Annelien L. Cavalli, Giacomo Chiocca, Susanna Clevers, Hans De Strooper, Bart Eggert, Angelika Ellenberg, Jan Fernandez, Xose M. Figlerowicz, Marek Gasser, Susan M. Hubner, Norbert Kjems, Jorgen Knoblich, Jurgen A. Krabbe, Grietje Lichter, Peter Linnarsson, Sten Marine, Jean-Christophe Marioni, John C. Marti-Renom, Marc A. Netea, Mihai G. Nickel, Dorthe Nollmann, Marcelo Novak, Halina R. Parkinson, Helen Piccolo, Stefano Pinheiro, Ines Pombo, Ana Popp, Christian Reik, Wolf Roman-Roman, Sergio Rosenstiel, Philip Schultze, Joachim L. Stegle, Oliver Tanay, Amos Testa, Giuseppe Thanos, Dimitris Theis, Fabian J. Torres-Padilla, Maria-Elena Valencia, Alfonso Vallot, Celine van Oudenaarden, Alexander Vidal, Marie Voet, Thierry Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine in the Helmholtz Association Berlin Germany Charité-Universitätsmedizin Berlin Germany Berlin Institute of Health (BIH) Berlin Germany German Center for Cardiovascular Research (DZHK) Partner Site Berlin Berlin Germany Institute for Biology Humboldt University of Berlin Berlin Germany Cardiovascular and Metabolic Sciences Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) Berlin Germany Department of Pediatric Oncology/Hematology Charité-Universitätsmedizin Berlin Berlin Germany Institut Curie CNRS PSL Research University Sorbonne Université Nuclear Dynamics Unit Equipe Labellisée Ligue contre le cancer Paris France VIB Center for Brain and Disease Research Leuven Belgium Department of Human Genetics KU Leuven Leuven Belgium Department of Neurosciences KU Leuven Leuven Belgium UK Dementia Research Institute at UCL University College London London UK Wellcome Sanger Institute Wellcome Genome Campus Cambridge UK Department of Immunology Weizmann Institute of Science Rehovot Israel Centre for Genomic Regulation (CRG) Barcelona Institute of Science and Technology Barcelona Spain CNAG-CRG Centre for Genomic Regulation Barcelona Institute of Science and Technology Barcelona Spain Universitat Pompeu Fabra Barcelona Spain ICREA Barcelona Spain CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria Department of Laboratory Medicine Medical University of Vienna Vienna Austria Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases Vienna Austria Department of Medical Humanities Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht The Netherlands Institute of Human Genetics UMR 9002 CNRS and University of Montpellier Montpellier France Department of Experimental Oncology IEO European Institute of Oncology IRCCS Milan Italy Department of Oncology and Hemato

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Erratum to: The sponge microbiome project

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Gigascience 2018年第12期7卷 giy145页

作者： Lucas Moitinho-Silva Shaun Nielsen Amnon Amir Antonio Gonzalez Gail L Ackermann Carlo Cerrano Carmen Astudillo-Garcia Cole Easson Detmer Sipkema Fang Liu Georg Steinert Giorgos Kotoulas Grace P McCormack Guofang Feng James J Bell Jan Vicente Johannes R Björk Jose M Montoya Julie B Olson Julie Reveillaud Laura Steindler Mari-Carmen Pineda Maria V Marra Micha Ilan Michael W Taylor Paraskevi Polymenakou Patrick M Erwin Peter J Schupp Rachel L Simister Rob Knight Robert W Thacker Rodrigo Costa Russell T Hill Susanna Lopez-Legentil Thanos Dailianis Timothy Ravasi Ute Hentschel Zhiyong Li Nicole S Webster Torsten Thomas Centre for Marine Bio-Innovation and School of Biological Earth and Environmental Sciences The University of New South Wales Sydney 2052 Australia. Department of Pediatrics University of California - San Diego La Jolla CA 92093 USA. Department of Life and Environmental Sciences Polytechnic University of Marche Ancona 60131 Italy. School of Biological Sciences University of Auckland Auckland New Zealand. Halmos College of Natural Sciences and Oceanography Nova Southeastern University Dania Beach FL 33004 USA. Wageningen University Laboratory of Microbiology Stippeneng 4 6708 WE Wageningen The Netherlands. State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai 200240 P.R. China. Hellenic Centre for Marine Research Institute of Marine Biology Biotechnology and Aquaculture Thalassocosmos 71500 Heraklion Greece. Zoology School of Natural Sciences Ryan Institute National University of Ireland Galway University Rd. Galway Ireland. School of Biological Sciences Victoria University of Wellington Wellington New Zealand. Hawaii Institute of Marine Biology 46-007 Lilipuna Road Kaneohe HI 96744-1346. Galvin Life Science Center University of Notre Dame Notre Dame IN 46556 USA. Ecological Networks and Global Change Group Theoretical and Experimental Ecology Station CNRS and Paul Sabatier University Moulis France. Department of Biological Sciences University of Alabama Tuscaloosa AL 35487 USA. INRA UMR1309 CMAEE Cirad UMR15 CMAEE 34398 Montpellier France. Department of Marine Biology Leon H. Charney School of Marine Sciences University of Haifa Haifa Israel. Australian Institute of Marine Science (AIMS) Townsville 4810 Queensland Australia. Department of Zoology George S. Wise Faculty of Life Sciences Tel Aviv University Tel Aviv 69978 Israel. Department of Biology and Marine Biology University of North Carolina Wilmington Wilmington NC 28409 USA. Institute for Chemistry and Biolog

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Author Correction: RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions

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Nature communications 2021年第1期12卷 3128页

作者： Alessandro Bonetti Federico Agostini Ana Maria Suzuki Kosuke Hashimoto Giovanni Pascarella Juliette Gimenez Leonie Roos Alex J Nash Marco Ghilotti Christopher J F Cameron Matthew Valentine Yulia A Medvedeva Shuhei Noguchi Eneritz Agirre Kaori Kashi Joachim Luginbühl Riccardo Cazzoli Saumya Agrawal Nicholas M Luscombe Mathieu Blanchette Takeya Kasukawa Michiel de Hoon Erik Arner Boris Lenhard Charles Plessy Gonçalo Castelo-Branco Valerio Orlando Piero Carninci RIKEN Center for Integrative Medical Sciences Yokohama Kanagawa 230-0045 Japan. alessandro.bonetti@riken.jp. Laboratory of Molecular Neurobiology Department Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden. alessandro.bonetti@riken.jp. The Francis Crick Institute 1 Midland Road London NW1 1AT UK. RIKEN Center for Integrative Medical Sciences Yokohama Kanagawa 230-0045 Japan. Department of Medicine (H7) Karolinska Institutet Stockholm 141 86 Sweden. Epigenetics and Genome Reprogramming Laboratory IRCCS Fondazione Santa Lucia Rome Italy. Faculty of Medicine Imperial College London Institute of Clinical Sciences London W12 0NN UK. MRC London Institute of Medical Sciences London W12 0NN UK. School of Computer Science McGill University Montréal QC Canada. Department of Biochemistry and Goodman Cancer Research Centre McGill University Montréal QC Canada. Institute of Bioengineering Research Centre of Biotechnology Russian Academy of Science 117312 Moscow Russia. Department of Computational Biology Vavilov Institute of General Genetics Russian Academy of Science 119991 Moscow Russia. Department of Biological and Medical Physics Moscow Institute of Physics and Technology 141701 Dolgoprudny Moscow Region Russia. Laboratory of Molecular Neurobiology Department Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden. Department of Experimental Oncology IEO European Institute of Oncology IRCCS Milan Italy. UCL Genetics Institute University College London London WC1E 6BT UK. Okinawa Institute of Science and Technology Graduate University 1919-1 Tancha Onna-son Kunigami-gun Okinawa 904-0495 Japan. Sars International Centre for Marine Molecular Biology University of Bergen 5008 Bergen Norway. Epigenetics and Genome Reprogramming Laboratory IRCCS Fondazione Santa Lucia Rome Italy. valerio.orlando@kaust.edu.sa. KAUST Environmental Epigenetics Program King Abdullah University of Science and Technology (KAUS

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Author Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

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Nature genetics 2018年第12期50卷 1754页

作者： Huipeng Li Elise T Courtois Debarka Sengupta Yuliana Tan Kok Hao Chen Jolene Jie Lin Goh Say Li Kong Clarinda Chua Lim Kiat Hon Wah Siew Tan Mark Wong Igor Cima Min-Han Tan Lawrence J K Wee Axel M Hillmer Iain Beehuat Tan Paul Robson Shyam Prabhakar Computational and Systems Biology Genome Institute of Singapore Singapore Singapore. Developmental Cellomics Laboratory Genome Institute of Singapore Singapore Singapore. Department of Computer Science and Engineering and Center for Computational Biology Indraprastha Institute of Information Technology Delhi India. Synthetic Biology Genome Institute of Singapore Singapore Singapore. Cancer Therapeutics and Stratified Oncology Genome Institute of Singapore Singapore Singapore. Department of Medical Oncology National Cancer Centre Singapore Singapore Singapore. Department of Pathology Singapore General Hospital Singapore Singapore. Department of Colorectal Surgery Singapore General Hospital Singapore Singapore. Institute of Bioengineering and Nanotechnology Singapore Singapore. Data Analytics Department Institute for Infocomm Research Singapore Singapore. Cancer Therapeutics and Stratified Oncology Genome Institute of Singapore Singapore Singapore. iain.tan.b.h@singhealth.com.sg. Department of Medical Oncology National Cancer Centre Singapore Singapore Singapore. iain.tan.b.h@singhealth.com.sg. Program in Cancer and Stem Cell Biology Duke-NUS Medical School Singapore Singapore. iain.tan.b.h@singhealth.com.sg. Developmental Cellomics Laboratory Genome Institute of Singapore Singapore Singapore. paul.robson@***. The Jackson Laboratory for Genomic Medicine Farmington Connecticut USA. paul.robson@***. Department of Genetics and Genome Sciences Institute for Systems Genomics University of Connecticut Farmington Connecticut USA. paul.robson@***. Department of Biological Sciences National University of Singapore Singapore Singapore. paul.robson@***. Computational and Systems Biology Genome Institute of Singapore Singapore Singapore. prabhakars@gis.a-star.edu.sg.

In the version of the article published, the author list is not accurate. Igor Cima and Min-Han Tan should have been authors, appearing after Mark Wong in the author list, while Paul Jongjoon Choi should not have been listed as an author. Igor Cima and Min-Han Tan both have the affiliation Institute of bioengineering and Nanotechnology, Singapore, Singapore, and their contributions should have been noted in the Author Contributions section as "I.C. preprocessed Primary Cell Atlas data with inputs from M.-H.T." The following description of the contribution of Paul Jongjoon Choi should not have appeared: "P.J.C. supported the smFISH experiments." In the 'RCA: global panel' section of the Online Methods, the following sentence should have appeared as the second sentence, "An expression atlas of human primary cells (the Primary Cell Atlas) was preprocessed similarly to in ref. 55," with new reference 55 (Cima, I. et al. Tumor-derived circulating endothelial cell clusters in colorectal cancer. science Transl. Med. 8, 345ra89, 2016).

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Correction to: Meeting report from the fourth meeting of the Computational Modeling in Biology Network (COMBINE)

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Standards in genomic sciences 2018年第1期13卷 17页

作者： Dagmar Waltemath Frank T Bergmann Claudine Chaouiya Tobias Czauderna Padraig Gleeson Carole Goble Martin Golebiewski Michael Hucka Nick Juty Olga Krebs Nicolas Le Novère Huaiyu Mi Ion I Moraru Chris J Myers David Nickerson Brett G Olivier Nicolas Rodriguez Falk Schreiber Lucian Smith Fengkai Zhang Eric Bonnet 1Department of Systems Biology and Bioinformatics University of Rostock Rostock Germany. 2Department of Computing and Mathematical Sciences California Institute of Technology Pasadena CA USA. 4Instituto Gulbenkian de Ciência - IGC Rua da Quinta Grande Oeiras Portugal. 3IPK Gatersleben Gatersleben Germany. 5Department of Neuroscience Physiology and Pharmacology University College London London UK. 6School of Computer Science The University of Manchester Manchester UK. 7Heidelberg Institute for Theoretical Studies Heidelberg Germany. 8EMBL-European Bioinformatics Institute Wellcome Trust Genome Campus Hinxton Cambridge UK. 14The Babraham Institute Babraham Research Campus Cambridge UK. 9Department of preventive medicine Keck School of Medicine University of Southern California Los Angeles CA USA. 10Center for Cell Analysis and Modeling University of Connecticut Health Center Farmington CT USA. 11Department of Electrical and Computer Engineering University of Utah Salt Lake City USA. 12Auckland Bioengineering Institute University of Auckland Auckland New Zealand. 13Systems Bioinformatics VU University Amsterdam Amsterdam The Netherlands. 15Martin Luther University Halle-Wittenberg Halle Germany. 16Monash University Melbourne Australia. Computational Biology Unit Laboratory of Systems Biology National Institute of Allergy and Infectious Diseases NIH Bethesda MD USA. 18Institut Curie Paris France. INSERM U900 75248 Paris France. 20Mines ParisTech 77300 Fontainebleau Paris France.

[This corrects the article DOI: 10.4056/sigs.5279417.].

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Author Correction: The interrelation of sleep and mental and physical health is anchored in grey-matter neuroanatomy and under genetic control

Communications biology

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Communications biology 2020年第1期3卷 290页

作者： Masoud Tahmasian Fateme Samea Habibolah Khazaie Mojtaba Zarei Shahrzad Kharabian Masouleh Felix Hoffstaedter Julia Camilleri Peter Kochunov B T Thomas Yeo Simon Bodo Eickhoff Sofie Louise Valk Institute of Medical Science and Technology Shahid Beheshti University Tehran Iran. Sleep Disorders Research Center Kermanshah University of Medical Sciences Kermanshah Iran. Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour) Research Centre Jülich 52425 Jülich Germany. Institute of Systems Neuroscience Heinrich Heine University Düsseldorf 40225 Düsseldorf Germany. Maryland Psychiatric Research Center University of Maryland School of Medicine Baltimore MD 21201 USA. Department of Electrical and Computer Engineering Clinical Imaging Research Centre N.1 Institute for Health and Memory Networks Program National University of Singapore Singapore 119077 Singapore. Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown MA 02114 USA. Centre for Sleep and Cognition National University of Singapore Singapore 119077 Singapore. NUS Graduate School for Integrative Sciences and Engineering National University of Singapore Singapore 119077 Singapore. Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour) Research Centre Jülich 52425 Jülich Germany. svalk@fz-juelich.de. Institute of Systems Neuroscience Heinrich Heine University Düsseldorf 40225 Düsseldorf Germany. svalk@fz-juelich.de.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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BT-02FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA

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Neuro-Oncology 2015年第SUPPL_3期17卷 iii3-iii3页

作者： Grasso, Catherine S. Tang, Yujie Truffaux, Nathalene Berlow, Noah E. Liu, Lining Debily, Marie-Anne Quist, Michael J. Davis, Lara Huang, Elaine C. Woo, Pamelyn J. Ponnuswami, Anitha Chen, Spenser Johung, Tessa Sun, Wenchao Kogiso, Mari Du, Yuchen Lin, Qi Huang, Yulun Hutt-Cabezas, Marianne Warren, Katherine E. Le Dret, Ludivine Meltzer, Paul S. Mao, Hua Quezado, Martha van Vuurden, Dannis G. Abraham, Jinu Fouladi, Maryam Svalina, Matthew N. Wang, Nicholas Hawkins, Cynthia Raabe, Eric Hulleman, Esther Spellman, Paul T. Li, Xiao-Nan Keller, Charles Pal, Ranadip Grill, Jacques Monje, Michelle Center for Spatial Systems Biomedicine Department of Molecular and Medical Genetics Oregon Health & Science University Portland OR USA These authors contributed equally to this work Depts. of Neurology Neurosurgery and Pediatrics Stanford University Stanford CA USA Unité Mixte de Recherche du Centre National de la Recherche Scientifique 8203 Institut Gustave Roussy et Université Paris-Sud Villejuif France Electrical and Computer Engineering Texas Tech University Lubbock TX USA Université d'Evry-Val d'Essone Evry France Pediatric Cancer Biology Program Papé Family Pediatric Research Institute Dept. of Pediatrics Oregon Health & Science University Portland OR USA Children's Cancer Therapy Development Institute Fort Collins CO USA Laboratory of Molecular Neurooncology Texas Children's Cancer Center Baylor College of Medicine Houston TX USA Department of Neurosurgery The First Affiliated Hospital of Soochow Suzhou China Departments of Oncology and Pathology Johns Hopkins University Baltimore MD USA National Cancer Institute Bethesda MD USA Department of Pediatric Oncology Hematology and Neuro-Oncology Research Group Cancer Center Amsterdam VU University Medical Center Amsterdam The Netherlands Cancer and Blood Diseases Institute Cincinnati Children's Hospital Medical Center Cincinnati OH USA Dept. of Paediatric Laboratory Medicine University of Toronto Scientist Labatt Brain Tumour Research Centre Hospital for Sick Children University of Toronto Toronto ON Canada Departement de Cancerologie de l'Enfant et de l'Adolescent Institut Gustave Roussy Université Paris-Sud Villejuif France

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Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM_2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019

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The Lancet Planetary Health 2022年第7期6卷 e586-e600页

作者： Burkart, Katrin Causey, Kate Cohen, Aaron J Wozniak, Sarah S Salvi, Devashri Digvijay Abbafati, Cristiana Adekanmbi, Victor Adsuar, Jose C Ahmadi, Keivan Alahdab, Fares Al-Aly, Ziyad Alipour, Vahid Alvis-Guzman, Nelson Amegah, Adeladza Kofi Andrei, Catalina Liliana Andrei, Tudorel Ansari, Fereshteh Arabloo, Jalal Aremu, Olatunde Aripov, Timur Babaee, Ebrahim Banach, MacIej Barnett, Anthony Bärnighausen, Till Winfried Bedi, Neeraj Behzadifar, Masoud Béjot, Yannick Bennett, Derrick A Bensenor, Isabela M Bernstein, Robert S Bhattacharyya, Krittika Bijani, Ali Biondi, Antonio Bohlouli, Somayeh Breitner, Susanne Brenner, Hermann Butt, Zahid A Cámera, Luis Alberto Cantu-Brito, Carlos Carvalho, Felix Cerin, Ester Chattu, Vijay Kumar Chauhan, Bal Govind Choi, Jee-Young Jasmine Chu, Dinh-Toi Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Daryani, Ahmad Davletov, Kairat De Courten, Barbora Demeke, Feleke Mekonnen Denova-Gutiérrez, Edgar Dharmaratne, Samath Dhamminda Dhimal, Meghnath Diaz, Daniel Djalalinia, Shirin Duncan, Bruce B El Sayed Zaki, Maysaa Eskandarieh, Sharareh Fareed, Mohammad Farzadfar, Farshad Fattahi, Nazir Fazlzadeh, Mehdi Fernandes, Eduarda Filip, Irina Fischer, Florian Foigt, Nataliya A Freitas, Marisa Ghashghaee, Ahmad Gill, Paramjit Singh Ginawi, Ibrahim Abdelmageed Gopalani, Sameer Vali Guo, Yuming Gupta, Rajat Das Habtewold, Tesfa Dejenie Hamadeh, Randah R Hamidi, Samer Hankey, Graeme J Hasanpoor, Edris Hassen, Hamid Yimam Hay, Simon I Heibati, Behzad Hole, Michael K Hossain, Naznin Househ, Mowafa Irvani, Seyed Sina Naghibi Jaafari, Jalil Jakovljevic, Mihajlo Jha, Ravi Prakash Jonas, Jost B Jozwiak, Jacek Jerzy Kasaeian, Amir Kaydi, Neda Khader, Yousef Saleh Khafaie, Morteza Abdullatif Khan, Ejaz Ahmad Khan, Junaid Khan, Md Nuruzzaman Khatab, Khaled Khater, Amir M Kim, Yun Jin Kimokoti, Ruth W Kisa, Adnan Kivimäki, Mika Knibbs, Luke D Kosen, Soewarta Koul, Parvaiz A Koyanagi, Ai Defo, Barthelemy Kuate Kugbey, Nuworza Lauriola, Paolo Lee, Paul H Leili, Mostafa Lewycka, Sonia Li, Shanshan Lim, Lee-Ling Li Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Division of Plastic and Reconstructive Surgery University of Washington Seattle WA United States Research Insights and Innovation Seattle WA United States Health Effects Institute Boston MA United States School of Public Health Boston University Boston MA United States Department of Juridical and Economic Studies La Sapienza University Rome Italy Department of Population Medicine Cardiff University Cardiff United Kingdom Sport Science Department University of Extremadura Badajoz Spain School of Public Health Imperial College London London United Kingdom Department of Primary Care and Public Health Imperial College London London United Kingdom Mayo Evidence-based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester MN United States John T. Milliken Department of Internal Medicine Washington University in St. Louis St. Louis MO United States Clinical Epidemiology Center US Department of Veterans Affairs (VA) St Louis MO United States Health Management and Economics Research Center Iran University of Medical Sciences Tehran Iran Department of Health Economics Iran University of Medical Sciences Tehran Iran Preventive Medicine and Public Health Research Center Iran University of Medical Sciences Tehran Iran Pars Advanced and Minimally Invasive Medical Manners Research Center Iran University of Medical Sciences Tehran Iran Department of Community and Family Medicine Iran University of Medical Sciences Tehran Iran Research Group in Hospital Management and Health Policies Universidad de la Costa (University of the Coast) Barranquilla Colombia Research Group in Health Economics University of Cartagena Cartagena Colombia Department of Biomedical Science University of Cape Coast Cape Coast Ghana Cardiology Department Ca

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM_2·5 originating from ambient and household air pollution. Methods: We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM_2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regression—Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM_2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM_2·5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings: In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM_2·5 exposure, with an estimated 3·78 (95% uncertainty interval 2·68–4·83) deaths per 100 000 population and 167 (117–223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13·4% (9·49–17·5) of deaths and 13·6% (9·73–17·9) of DALYs due to type 2 diabetes were contributed by ambient PM2·5, and 6·50% (4·22–9·53) of deaths and 5·92% (3·81–8·64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South Am

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Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing

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Nature biotechnology 2020年第4期38卷 504页

作者： Christian Lieven Moritz E Beber Brett G Olivier Frank T Bergmann Meric Ataman Parizad Babaei Jennifer A Bartell Lars M Blank Siddharth Chauhan Kevin Correia Christian Diener Andreas Dräger Birgitta E Ebert Janaka N Edirisinghe José P Faria Adam M Feist Georgios Fengos Ronan M T Fleming Beatriz García-Jiménez Vassily Hatzimanikatis Wout van Helvoirt Christopher S Henry Henning Hermjakob Markus J Herrgård Ali Kaafarani Hyun Uk Kim Zachary King Steffen Klamt Edda Klipp Jasper J Koehorst Matthias König Meiyappan Lakshmanan Dong-Yup Lee Sang Yup Lee Sunjae Lee Nathan E Lewis Filipe Liu Hongwu Ma Daniel Machado Radhakrishnan Mahadevan Paulo Maia Adil Mardinoglu Gregory L Medlock Jonathan M Monk Jens Nielsen Lars Keld Nielsen Juan Nogales Intawat Nookaew Bernhard O Palsson Jason A Papin Kiran R Patil Mark Poolman Nathan D Price Osbaldo Resendis-Antonio Anne Richelle Isabel Rocha Benjamín J Sánchez Peter J Schaap Rahuman S Malik Sheriff Saeed Shoaie Nikolaus Sonnenschein Bas Teusink Paulo Vilaça Jon Olav Vik Judith A H Wodke Joana C Xavier Qianqian Yuan Maksim Zakhartsev Cheng Zhang Novo Nordisk Foundation Center for Biosustainability Technical University of Denmark Lyngby Denmark. Systems Biology Lab Amsterdam Institute of Molecular and Life Sciences (AIMMS) Vrije Universiteit Amsterdam Amsterdam the Netherlands. BioQUANT/COS Heidelberg University Heidelberg Germany. Ecole Polytechnique Fédérale de Lausanne Laboratory of Computational Systems Biotechnology Lausanne Switzerland. iAMB-Institute of Applied Microbiology ABBt-Aachen Biology and Biotechnology RWTH Aachen University Aachen Germany. Department of Bioengineering University of California La Jolla CA USA. Department of Chemical Engineering and Applied Chemistry University of Toronto Toronto Ontario Canada. Human Systems Biology Laboratory Instituto Nacional de Medicina Genomica & Coordinación de la Investigación Científica-Red de Apoyo a la Investigación UNAM Mexico City Mexico. Institute for Systems Biology Seattle WA USA. Computational Systems Biology of Infection and Antimicrobial-Resistant Pathogens Institute for Biomedical Informatics (IBMI) Tübingen Germany. Department of Computer Science University of Tübingen Tübingen Germany. German Center for Infection Research (DZIF) partner site Tübingen Tübingen Germany. Australian Institute for Bioengineering and Nanotechnology The University of Queensland Brisbane Queensland Australia. Argonne National Laboratory Lemont IL USA. Analytical Biosciences Division of Systems Biomedicine and Pharmacology Leiden Academic Centre for Drug Research Leiden University Leiden the Netherlands. Department of Systems Biology Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas (CNB-CSIC) Madrid Spain. Centro de Biotecnología y Genómica de Plantas (CBGP UPM-INIA) Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) Madrid Spain. Department of Animal and Aquacultural Sciences Faculty of Biosciences Norwegian University of Life Sciences Oslo Norway

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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