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A generalized adder for cell size homeostasis: Effects on stochastic clonal proliferation

Biophysical Journal 2025年第9期124卷 1376-1386页

作者： Nieto, César Vargas-García, César Augusto Singh, Abhyudai Department of Electrical and Computer Engineering University of Delaware Newark DE United States AGROSAVIA - Corporacion Colombiana de Investigacion Agropecuaria Cundinamarca Mosquera Colombia Department of Electrical and Computer Engineering Biomedical Engineering Mathematical Sciences Interdisciplinary Neuroscience Program University of Delaware Newark DE United States

Measurements of cell size dynamics have revealed phenomenological principles by which individual cells control their size across diverse organisms. One of the emerging paradigms of cell size homeostasis is the adder, where the cell cycle duration is established such that the cell size increase from birth to division is independent of the newborn cell size. We provide a mechanistic formulation of the adder, considering that cell size follows any arbitrary nonexponential growth law. Our results show that the main requirement to obtain an adder regardless of the growth law (the time derivative of cell size) is that cell cycle regulators are produced at a rate proportional to the growth law, and cell division is triggered when these molecules reach a prescribed threshold level. Among the implications of this generalized adder, we investigate fluctuations in the proliferation of single-cell-derived colonies. Considering exponential cell size growth, random fluctuations in clonal size show a transient increase and then eventually decay to zero over time (i.e., clonal populations become asymptotically more similar). In contrast, several forms of nonexponential cell size dynamics (with adder-based cell size control) yield qualitatively different results: clonal size fluctuations monotonically increase over time, reaching a nonzero value. These results characterize the interplay between cell size homeostasis at the single-cell level and clonal proliferation at the population level, explaining the broad fluctuations in clonal sizes seen in barcoded human cell lines. © 2025 Biophysical Society

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Enhancing waste sorting and recycling efficiency: robust deep learning-based approach for classification and detection

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Neural Computing and Applications 2025年第6期37卷 4567-4583页

作者： Sayem, Faizul Rakib Islam, Md. Sakib Bin Naznine, Mansura Nashbat, Mohammad Hasan-Zia, Mazhar Kunju, Ali K Ansaruddin Khandakar, Amith Ashraf, Azad Majid, Molla Ehsanul Kashem, Saad Bin Abul Chowdhury, Muhammad E. H. Department of Electrical and Electronic Engineering University of Dhaka Dhaka Bangladesh Department of Biomedical Engineering Military Institute of Science and Technology Dhaka Bangladesh Department of Computer Science & Engineering Rajshahi University of Engineering & Technology Rajshahi6204 Bangladesh Chemical Engineering Department University of Doha for Science and Technology Doha Qatar Department of Electrical Engineering Qatar University Doha2713 Qatar Computer Applications Department Academic Bridge Program Qatar Foundation Doha Qatar Department of Computing Science AFG College With the University of Aberdeen Doha Qatar

Given the severity of waste pollution as a major environmental concern, intelligent and sustainable waste management is becoming increasingly crucial in both developed and developing countries. The material composition and volume of urban solid waste are key considerations in processing, managing, and utilizing city waste. Deep learning technologies have emerged as viable solutions to address waste management issues by reducing labor costs and automating complex tasks. However, the limited number of trash image categories and the inadequacy of existing datasets have constrained the proper evaluation of machine learning model performance across a large number of waste classes. In this paper, we present robust waste image classification and object detection studies using deep learning models, utilizing 28 distinct recyclable categories of waste images comprising a total of 10,406 images. For the waste classification task, we proposed a novel dual-stream network that outperformed several state-of-the-art models, achieving an overall classification accuracy of 83.11%. Additionally, we introduced the GELAN-E (generalized efficient layer aggregation network) model for waste object detection tasks, obtaining a mean average precision (mAP50) of 63%, surpassing other state-of-the-art detection models. These advancements demonstrate significant progress in the field of intelligent waste management, paving the way for more efficient and effective solutions. © The Author(s) 2024.

关键词： Deep learning for waste management Intelligent waste management Object detection in waste management Sustainable waste processing Urban solid waste Waste image classification

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Compact 5G Broadband Antenna for Sub-6 GHz Wireless Applications

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IEEE Access 2025年 13卷 79444-79450页

作者： Fattoum, Manal K. Joujou, Samira M. Ibrahim, Sarah M. El-Halabi, Heba Beirut Arab University Faculty of Engineering Communications and Electronics Engineering Program Department of Electrical and Computer Engineering Debbieh Lebanon

The design and analysis of a compact broadband antenna supporting the long-term evolution (LTE) bands 41/42/43/46/48/52 and the sub-6 GHz bands N46/N77/N78/N79, Bluetooth, and Wi-Fi are presented. The proposed antenna consists of a 50-ohm microstrip feedline, a Yagi-shaped patch radiator, and a partial ground plane under the feedline. The slot-loading technique is employed to achieve a wide band of operation and to minimize the overall size of the antenna. Using the low-loss dielectric material substrate, Rogers RO4003C, the form factor of the antenna is appreciably reduced to 26 × 17 × 0.813 mm3 without compromising the performance result of the antenna. The finite element method-based high-frequency electromagnetic solver from ANSYS Corporation is used to simulate and optimize the antenna. A prototype of the designed antenna is fabricated and measured to verify its performance. It is observed that in the operating impedance bandwidth from 2.44 GHz to 5.74 GHz (voltage standing wave ratio © 2013 IEEE.

关键词： Microstrip antennas

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Design and Implementation of Test Infrastructure for Higher Parallel Wafer Level Testing of System-on-Chip

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IEEE Access 2025年 13卷 37493-37500页

作者： Lee, Seung-Han Park, Jin Hwan Lee, Young-Woo Inha University Department of Electrical and Computer Engineering Incheon22212 Korea Republic of Inha University Program in Semiconductor Convergence Incheon22212 Korea Republic of Teradyne Inc. Semiconductor Test Division MA North Reading01864 United States

Semiconductor companies have been striving to reduce their manufacturing costs. High parallelism is a key factor in reducing costs during wafer-level testing. Wafer testing is conducted using Automatic Test Equipment (ATE) along with test infrastructures such as the Prober Interface Board (PIB), signal tower, and probe card. In this paper, we present the mechanical and electrical details of a wafer-level test infrastructure designed for higher parallel testing of system-on-chips (SoCs). In previous test infrastructures, a high site count was constrained by the available probe pins on the signal tower for wafer testing. However, the proposed signal tower addresses this bottleneck by utilizing a combination of 620 pin and 731 pin modules. This allows more probe pins to transmit signals from the ATE instrument, enabling multi-site testing. The number of available probe pins increased by 68.96% compared to the state-of-the-art infrastructure, without compromising the application area. The experimental results demonstrate that our proposed test infrastructure is suitable for mass production at the wafer-level, considering factors such as deflection, total compression forces, and electrical specifications. © 2025 The Authors. This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://***/licenses/by/4.0/

关键词： System-on-chip

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A Multifunctional Hydrogel with Multimodal Self-Powered Sensing Capability and Stable Direct Current Output for Outdoor Plant Monitoring Systems

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Nano-Micro Letters 2025年第4期17卷 1-24页

作者： Xinge Guo Luwei Wang Zhenyang Jin Chengkuo Lee Department of Electrical&Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117576Singapore Center for Intelligent Sensors and MEMS(CISM) National University of Singapore5 Engineering Drive 1Singapore 117608Singapore NUS Graduate School-Integrative Sciences and Engineering Program(ISEP) National University of SingaporeSingapore 119077Singapore Research Center for Sustainable Urban Farming(SUrF) National University of SingaporeSingapore 117558Singapore

Smart farming with outdoor monitoring systems is critical to address food shortages and sustainability *** systems facilitate informed decisions that enhance efficiency in broader environmental *** outdoor systems equipped with energy harvesters and self-powered sensors often struggle with fluctuating energy sources,low durability under harsh conditions,non-transparent or non-biocompatible materials,and complex ***,a multifunctional hydrogel is developed,which can fulfill all the above requirements and build selfsustainable outdoor monitoring systems solely by *** can serve as a stable energy harvester that continuously generates direct current output with an average power density of 1.9 W m^(-3)for nearly 60 days of operation in normal environments(24℃,60%RH),with an energy density of around 1.36×10^(7)J m^(-3).It also shows good self-recoverability in severe environments(45℃,30%RH)in nearly 40 days of continuous ***,this hydrogel enables noninvasive and self-powered monitoring of leaf relative water content,providing critical data on evaluating plant health,previously obtainable only through invasive or high-power consumption *** potential extends to acting as other self-powered environmental *** multifunctional hydrogel enables self-sustainable outdoor systems with scalable and low-cost production,paving the way for future agriculture.

关键词： Self-powered sensor Hydrogel Energy harvester Outdoor farming Self-sustainable IoT

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Hybrid 1D and 2D CNN-Transformer Architectures for Multilabel 12-Lead EKG Anomaly Detection

Hybrid 1D and 2D CNN-Transformer Architectures for Multilabe...

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Annual Conference on Information Sciences and Systems (CISS)

作者： Ian DeTore John Samsundar Cleon Davis Electrical and Computer Engineering Program Johns Hopkins University Baltimore MD USA Electrical and Computer Engineering Program Johns Hopkins University Laurel MD USA

ISBN: (数字)9798331513269

ISBN: (纸本)9798331513276

This study introduces two novel hybrid machine-learning architectures for multilabel anomaly detection in electrocardiograms (EKGs): a 1D modified ResNet combined with a transformer encoder and an equivalent 2D ResNet-Transformer hybrid. This work is among the first to utilize two separate CNN-transformer architectures tailored specifically for temporal and spatial features in multilabel EKG data. Our models address the challenges of imbalanced data and multilabel classification by leveraging the PTB-XL dataset, containing over 21,000 annotated samples across five diagnostic superclasses, namely myocardial infarction, conduction disturbances, hypertrophy, ST-T wave changes, and normal EKGs. We applied advanced data augmentation techniques to mitigate class imbalance, including the Multilabel Synthetic Minority Over-Sampling Technique (ML-SMOTE). Additionally, we employed digital signal processing to denoise the EKG signals and convert time-series data into time-frequency representations for 2D modeling. Experimental results demonstrate the effectiveness of our approach, with the 1D model achieving an area under the curve (AUC) of 91.5% and the 2D model achieving an AUC of 87.2%. These findings demonstrate the potential of specialized architectures for comprehensive multilabel EKG anomaly detection.

关键词： Time-frequency analysis Multi label classification Machine learning Electrocardiography Myocardium Brain modeling Transformers Data models Electromyography Anomaly detection

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Using Random Forest and Linear SVM for Dyslexia Classification on Hebb-Williams Mazes 59

Using Random Forest and Linear SVM for Dyslexia Classificati...

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59th Annual Conference on Information Sciences and Systems, CISS 2025

作者： Kaushik, Padmanabh Yu, Yih-Choung Gabel, Lisa Lafayette College Department of Electrical and Computer Engineering EastonPA18042 United States Lafayette College Department of Psychology and Neuroscience Program EastonPA18042 United States

ISBN: (纸本)9798331513269

Dyslexia is a learning disability that negatively impacts an individual's ability to read, write, spell, and sometimes speak. It results in difficulties in recognizing and decoding words and patterns, despite normal level of education and intelligence. Studies have shown that early detection of dyslexia is vital for improving learning abilities in young children. Many virtual platforms exist for diagnosing and rehabilitating dyslexia;however, most require tests that measure reading skills. Since developing reading capabilities can delay the detection of dyslexia, a gaming platform based on Hebb-Williams mazes has been developed. This platform does not rely on reading skills and can diagnose dyslexia in young children. This paper presents a machine learning driven approach using two algorithms - Random Forest and Linear SVM - to classify reading abilities based on data from participants performing virtual maze tasks, which are indicative of symptoms of dyslexia. Results from this study indicate that it is possible to predict dyslexia with up to 95% accuracy based on a participant's performance in virtual gaming environments. © 2025 IEEE.

关键词： Adversarial machine learning

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Damage-Free Neutral Beam Etching for Gate Recess in E-Mode AlGaN/GaN HEMTs

IEEE Electron Device Letters

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IEEE Electron Device Letters 2025年第5期46卷 705-708页

作者： Chen, Yi-Ho Chu, Fu-Chuan Aslam, Muhammad Lee, Yao-Jen Li, Yiming Samukawa, Seiji National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Graduate Degree Program of College of Electrical and Computer Engineering Hsinchu300093 Taiwan National Chung-Shan Institute of Science and Technology Solid State Devices Section Electronic System Research Division Taoyuan325 Taiwan National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Electrical Engineering and Computer Science International Graduate Program Hsinchu300093 Taiwan Institute of Pioneer Semiconductor Innovation National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Institute of Pioneer Semiconductor Innovation Institute of Artificial Intelligence Innovation National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Institute of Biomedical Engineering Department of Electronics and Electrical Engineering Institute of Communications Engineering Hsinchu300093 Taiwan National Yang Ming Chiao Tung University Institute of Communications Engineering Department of Electronics and Electrical Engineering Hsinchu300093 Taiwan

Recess gate etching is a critical technique for achieving enhancement-mode (E-mode) AlGaN/GaN high-electron mobility transistors (HEMTs) because the interface is susceptible to the etching damage. This study fabricates recess gates using the neutral beam etching (NBE) technique. By adjusting the aperture thickness in the NBE apparatus, we simulate both NB-mode and plasma-mode etching. The electrical characteristics of E-mode HEMTs fabricated using these two modes are analyzed and compared through DC, noise, and pulsed IV measurements. The results demonstrate that NB-recessed HEMTs exhibit superior performance. © 1980-2012 IEEE.

关键词： Aluminum gallium nitride

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Adaptive Input Sampling: A Novel Approach for Efficient Object Detection in High Resolution Traffic Monitoring Images

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IEEE Access 2025年 13卷 73003-73021页

作者： Gebre, Tewodros Syum Wasehun, Eden Tsehaye Dorbu, Freda Elikem Agboola, Gazali Oluwasegun Hashemi-Beni, Leila Karimoddini, Ali NC AandT State University Applied Science and Technology Program GreensboroNC United States NC AandT State University Department of Computational Data Science and Engineering GreensboroNC United States NC AandT State University Geomatics Program Department of Built Environment GreensboroNC United States NC AandT State University Department of Electrical and Computer Engineering GreensboroNC United States

Real-time traffic monitoring is crucial for efficient transportation management, but it poses significant computational challenges, particularly when dealing with high-resolution videos. Most modern traffic monitoring systems employ object detection models followed by object tracking models, which require processing every frame of the video footage to detect and track vehicles. However, even efficient object detection models are computationally expensive, making it difficult to process high-resolution videos in real-time. To address this challenge, we introduce an Adaptive Input Sampler (AIS) as a preprocessing module that selectively activates the object detector only when vehicles are present in the scene. The AIS targets the area of the frame where vehicles are detected and samples that area without compressing the sample, thereby reducing the computational load on the object detector. By doing so, the AIS enables significant computational savings, especially when fewor no vehicles are present in the monitored scene. Our experiments demonstrate that the AIS achieves 96.40% traffic counting accuracy and 95.60% classification accuracy, while reducing the data size for analysis by up to 79.00%. AIS presents a promising solution to optimize the volume of input data in traffic monitoring applications, improve computational efficiency, and speed up inference results. © 2013 IEEE.

关键词： Footage counters

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Real-time Computation of E-field in Transcranial Magnetic Stimulation for Neuronavigation and Optimization

Real-time Computation of E-field in Transcranial Magnetic St...

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2025 United States National Committee of URSI National Radio Science Meeting, USNC-URSI NRSM 2025

作者： Hasan, Nahian I. Dannhauer, Moritz Wang, Dezhi Deng, Zhi-De Gomez, Luis J. Elmore Family School of Electrical and Computer Engineering Purdue University WLIN United States National Institute of Mental Health Intramural Research Program National Institutes of Health United States

ISBN: (纸本)9781946815200

Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique used for the treatment of depression, as well as various neurological and psychiatric disorders. There has been ongoing interest in developing fast E-field solvers that can be easily incorporated into neuronavigation systems to facilitate real-time E-field in targeted brain regions, optimizing dosing parameters. © 2025 USNC-URSI.

关键词： Neurons

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