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SURG-01. DIFFERENTIATION OF GLIOBLASTOMA AND MALIGNANT MENINGIOMA FROM NORMAL BRAIN BY TISSUE STIFFNESS UTILIZING MICROSURGICAL FORCEPS EQUIPPED WITH HAPTICS TECHNOLOGY

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Neuro-Oncology 2023年第SUPPLEMENT_5期25卷 v260–v261页

作者： Ezaki, Taketo Kisima, Kohki Shibao, Shunsuke Matsunaga, Takuya Pareira, Eriel Sandika Kitamura, Yohei Takahara, Kento Iwama, Takashi Sampetrean, Oltea Ohnishi, Kouhei Shimono, Tomoyuki Sasaki, Hikaru Keio University School of Medicine Department of Neurosurgery Shinjuku-ku Tokyo Japan Yokohama National University School of Engineering Science Department of Educational Program for Electrical and Computer Engineering Yokohama-shi Japan Keio University School of Medicine Department of Neurosurgery Shinjuku-ku Japan Kanagawa Institute of Industrial Science and Technology Kawasaki-shi Japan Keio University School of Medicine Department of Microbiology and Immunology Shinjuku-ku Japan Keio University Haptics Research Center Kawasaki-shi Japan Tokyo Dental College Ichikawa General Hospital Department of Neurosurgery Ichikawa-shi Chiba Japan

Stiffness of human cancers strongly correlate with their pathology, and it is reported that stiffness can be used as a biomarker. Furthermore, comprehensive analysis has suggested the usefulness of cancer stiffness in diagnosis and malignancy prediction and its association with molecular expression, as well as its potential for predicting and diagnosing postoperative complications. Neurosurgeons perform tumor resection relying on the sensations that they feel with their own fingertips (tactile sensation), but it takes years of surgical experience to accurately distinguish brain tumor from the surrounding normal brain *** is a new technology regarding touching sensation. Especially, our technology, real haptics, can communicate, record, and reproduce the real sensation. It is also possible to measure and analyze the physical property such as stiffness of the touching object from the obtained haptic *** developed a surgical forceps equipped with haptics technology to distinguish brain tumor tissue from surrounding normal brain tissue. three glioblastoma cell lines (SF126, U87, U251) and a malignant meningioma cell line (IOMM-Lee) were each transplanted intracranially into 5 nude mice. Tumor size was periodically monitored and mice were euthanized at appropriate time points. The stiffness of the tumor and normal brain tissue was measured using a master-slave integrated surgical forceps prototype. The results statistically showed that all four types of brain tumor tissues were stiffer than normal brain tissues. (p = 0.001) In addition, malignant meningioma was statistically stiffer than glioblastomas. (p = 0.025) This result is consistent with actual surgical *** have shown that our surgical forceps has the ability to distinguish pathology of brain tumors as well as to distinguish brain tumor from normal brain tissue. The forceps is also helpful for the neurosurgeons to sense minute change in tissue stiffness.

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Manipulating Multiple order parameters via oxygen vacancies: The case of Eu0.5Ba0.5TiO3-δ

arXiv

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arXiv 2017年

作者： Li, Weiwei He, Qian Wang, Le Zeng, Huizhong Bowlan, John Ling, Langsheng Yarotski, Dmitry A. Zhang, Wenrui Zhao, Run Dai, Jiahong Gu, Junxing Shen, Shipeng Guo, Haizhong Pi, Li Wang, Haiyan Wang, Yongqiang Velasco-Davalos, Ivan A. Wu, Yangjiang Hu, Zhijun Chen, Bin Li, Run-Wei Sun, Young Jin, Kuijuan Zhang, Yuheng Chen, Hou-Tong Ju, Sheng Ruediger, Andreas Shi, Daning Borisevich, Albina Y. Yang, Hao College of Science Nanjing University of Aeronautics and Astronautics Nanjing211106 China Department of Materials Science and Metallurgy University of Cambridge CambridgeCB3 0FS United Kingdom Materials Science and Technology Division Oak Ridge National Laboratory Oak RidgeTN37831 United States Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Science Beijing100190 China State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology Chengdu610054 China Center for Integrated Nanotechnologies MS K771 Los Alamos National Laboratory Los AlamosNM87545 United States High Magnetic Field Laboratory Chinese Academy of Science Hefei230031 China Materials Science and Engineering Program Department of Electrical and Computer Engineering Texas A&M University College StationTX77843-3128 United States College of Physics Optoelectronics and Energy Soochow University Suzhou215006 China Materials Science and Technology Division Los Alamos National Laboratory Los AlamosNM87545 United States 1650 Boul. Lionel Boulet VarennesQCJ3X 1S2 Canada Center for Soft Condensed Matter Physics and Interdisciplinary Research Soochow University Suzhou215006 China Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology and Engineering Chinese Academy of Science Ningbo315201 China

Controlling functionalities, such as magnetism or ferroelectricity, by means of oxygen vacancies (VO) is a key issue for the future development of transition metal oxides. Progress in this field is currently addressed through VO variations and their impact on mainly one order parameter. Here we reveal a new mechanism for tuning both magnetism and ferroelectricity simultaneously by using VO. Combined experimental and density-functional theory studies of Eu0.5Ba0.5TiO3-δ, we demonstrate that oxygen vacancies create Ti3+ 3d1 defect states, mediating the ferromagnetic coupling between the localized Eu 4f7 spins, and increase an off-center displacement of Ti ions, enhancing the ferroelectric Curie temperature. The dual function of Ti sites also promises a magnetoelectric coupling in the Eu0.5Ba0.5TiO3-δ. Copyright © 2017, The Authors. All rights reserved.

关键词： Oxygen vacancies

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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Corrigendum to: Spatial Topography of Individual-Specific Cortical Networks Predicts Human Cognition, Personality and Emotion

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Cerebral cortex (New York, N.Y. : 1991) 2021年第8期31卷 3974页

作者： Ru Kong Jingwei Li Csaba Orban Mert R Sabuncu Hesheng Liu Alexander Schaefer Nanbo Sun Xi-Nian Zuo Avram J Holmes Simon B Eickhoff B T Thomas Yeo Department of Electrical and Computer Engineering ASTAR-NUS Clinical Imaging Research Centre Singapore Institute for Neurotechnology and Memory Networks Program National University of Singapore Singapore. School of Electrical and Computer Engineering Cornell University Ithaca NY USA. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown MA USA. CAS Key Laboratory of Behavioral Sciences and Research Center for Lifespan Development of Brain and Mind (CLIMB) Institute of Psychology Beijing China. University of Chinese Academy of Sciences Beijing China. Department of Psychology Yale University New Haven CT USA. Institute for Systems Neuroscience Medical Faculty Heinrich-Heine University Düsseldorf Düsseldorf Germany. Institute of Neuroscience and Medicine Brain & Behaviour (INM-7) Research Center Jülich Jülich Germany. Centre for Cognitive Neuroscience DukeNUS Medical School Singapore. NUS Graduate School for Integrative Sciences and Engineering National University of Singapore Singapore.

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Integration of Machine-Learned Force Fields for Phonon DOS in Nanoscale Heterostructures

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Microscopy and Microanalysis 2024年第SUPPLEMENT_1期30卷

作者： Walker, Harrison A Hoglund, Eric R Bao, De-Liang Kamal Hussain, Md Ni, Haoyang Mamun, Abdullah Baxter, Jefferey Khan, Asif Caldwell, Joshua D Hopkins, Patrick E Hachtel, Jordan A Pantelides, Sokrates T Dept. of Physics and Astronomy Vanderbilt Univ. Nashville TN United States Interdisciplinary Materials Science Program Vanderbilt Univ. Nashville TN United States Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak Ridge TN United States Dept. of Materials Science and Engineering Univ. of Virginia Charlottesville VA United States Dept. of Electrical Engineering Univ. of South Carolina Columbia SC United States Dept. of Materials Science and Engineering Univ. of Illinois at Urbana-Champaign Urbana IL United States Materials Research Laboratory Univ. of Illinois at Urbana-Champaign Urbana IL United States Dept. of Mechanical Engineering Vanderbilt Univ. Nashville TN United States Dept. of Mechanical and Aerospace Engineering Univ. of Virginia Charlottesville VA United States Dept. of Physics Univ. of Virginia Charlottesville VA United States Dept. of Electrical and Computer Engineering Vanderbilt Univ. Nashville TN United States

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NTDS - A PAGE IN NAVAL HISTORY

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NAVAL ENGINEERS JOURNAL 1988年第3期100卷 53-61页

作者： SWENSON, EN MAHINSKE, EB STOUTENBURGH, JS Capt. Erick N. Swenson USNR (Ret.):is a project manager for special projects in the Surface Ship Systems Division Hughes Aircraft Company Fullerton Calif where he has been employed since his retirement from the U.S. Navy in 1975. Originally trained as an electronics technician during WWII in the Captain Eddy program he later received a BS degree in electrical engineering from the University of Rochester Rochester N. Y. in 1950. Subsequent engineering education was received at the University of Pittsburgh Pittsburgh Penn. and the Naval Postgraduate School Monterey Calif. After commissioning he was ordered to duty as the electronics division officer on the USSMissouri(BB-63) and electronics ships superintendent at Hunters Point Naval Shipyard San Francisco Calif. When the design of the Naval Tactical Data System began in the mid-1950s Lt. (j.g.) Swenson was ordered to the Bureau of Ships Navy Department Washington D.C. as the junior engineering duty only officer assigned to the project. From 1962 to 1965 LCdr. Swenson was assigned as the BuShips technical representative on the program at Remington Rand Univac St. Paul Minn. For the next ten years he returned to BuShips/NavSea/NAVSEC as the NTDS project officer. During this time the project expanded considerably foreign military sales were heavily involved and interoperability with other services and countries were established. His final effort on active duty was to instigate the redesign of the previousSpruanceclass destroyers into the newerAdmiral Kiddclass improvement program. He is a registered professional electrical engineer in the State of California listed inWho's Who in the Worldis a life member of ASNE and chairman of the Long Beach/Greater LA Section. Capt. Edmund B. Mahinske USN (Ret.):is an alumnus of the U.S. Naval Academy the Massachusetts Institute of Technology and the Harvard Business School. His technical background is in electronics and he specialized in the management of programs involving the application of comp

A little over thirty years ago, a group of naval engineers were assembled by the Bureau of Ships to develop a new system approach to the combat information center (CIC). The CIC of World War II, with its “grease pencil” plots and voice telling of tactical information from sensors and other ships, could no longer provide the timely, coordinated reaction to postwar threats. This project group led the Navy into the new world of large-scale, high-speed digital electronics and into a new mode of conducting naval warfare as well. There were no off-the-shelf computers of the requisite capability, size and reliability; what were available were monstrous vacuum tube computers. There were no display equipments that were “conversant” in both the digital language of the computer and the analog language of the sensors and the weapon systems. Who ever heard, at that time, of a computer running a tactical communication net automatically? It was hard enough to find sufficient numbers of engineers who knew what a digital computer was. This paper, by three naval engineers in the implementing engineering office, depicts the evolvement of the Naval Tactical Data Systems (NTDS) as they saw it. It discusses the problems that stemmed from the transition from the old world of analog into the new digital world, the system concepts that steered the development; the key decisions that were made; new electronic equipment and processes that became necessary; and the need of the mangagement to face the real world of deadlines, ship schedules and operational requirements.

关键词： NAVAL WARFARE

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Designing the Application of Security Text Messages Into Audio Files Using Data Encryption Standard (DES) Algorithms Using the End Of File (EOF) Method

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Journal of Physics: Conference Series 2019年第1期1363卷

作者： A M H Pardede Anggi Pramana Muhammad Zarlis Akbar Iskandar Rosida Tiurma Manurung S Sriadhi Citra Kurniawan Abdurrozzaq Hasibuan Nurintan Asyiah Siregar Ayu Esteka Sari Indrya Mulyaningsih Teguh Hidayat Iskandar Alam Ibrahim Tri Listyorini Edy Winarno Tulus STMIK Kaputama Binjai Sumatera Utara Indonesia Department of Computer Science Universitas Sumatera Utara Medan Indonesia Department of Informatics STMIK AKBA Makassar Indonesia Graduate Program in Scientific Psychology Universitas Kristen Maranatha Indonesia Department of Electrical Engineering Universitas Negeri Medan Indonesia Department of Electrical Engineering Sekolah Tinggi Teknik Malang Indonesia Faculty of Engineering Universitas Islam Sumatera Utara Medan Indonesia Department of Management STIE Labuhanbatu Sumatera Utara Indonesia Department of Management STIE Sakti Alam Kerinci Jambi Indonesia Department of Indonesian Language Teaching Institut Agama Islam Negeri Syekh Nurjati Cirebon Indonesia Department of Informatics Engineering Universitas Muhammadiyah Sorong Sorong Indonesia Department of English Education Universitas Muhammadiyah Sorong Sorong Indonesia Department of Informatics Universitas Muria Kudus Indonesia Faculty of Information Technology Universitas Stikubank Semarang Indonesia Department of Mathematics Universitas Sumatera Utara Medan Indonesia

There are several ways to deal with security issues of confidential data sent via the internet, including using cryptographic techniques and steganography. Steganography is the science and art of concealing information / messages in a media in such a way that its existence is not detected by other parties who are not entitled to the information. Instead, cryptography disguises the meaning of a message, but does not hide that there is a message because the file looks suspicious. The Steganography technique used here was End Of File (EOF). The EOF technique described how to add data or files at the end of the image file. For this technique, the size of data or files that will be hidden could be larger than the size of the image file. The hidden data will be inserted at the end of the file so that it will not affect the image. This steganography application is also equipped with a cryptographic function Data Encryption Standard (DES) at the time of insertion of data that functions as a generator code and encrypts data, so that the security of a data in the file is more protected and protected from those who are not entitled to know the data.

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Combined effects of hydrometeorological hazards and urbanisation on dengue risk in Brazil: a spatiotemporal modelling study

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The Lancet Planetary Health 2021年第4期5卷 e209-e219页

作者： Lowe, Rachel Lee, Sophie A Brady, Oliver J Bastos, Leonardo Carrasco-Escobar, Gabriel de Castro Catão, Rafael Colón-González, Felipe J Barcellos, Christovam Carvalho, Marilia Sá Blangiardo, Marta Rue, Håvard Gasparrini, Antonio Centre for Mathematical Modelling of Infectious Diseases London School of Hygiene & Tropical Medicine London United Kingdom Centre on Climate Change and Planetary Health London School of Hygiene & Tropical Medicine London United Kingdom Department of Infectious Disease Epidemiology London School of Hygiene & Tropical Medicine London United Kingdom Department of Public Health Environments and Society London School of Hygiene & Tropical Medicine London United Kingdom Centre for Statistical Modelling London School of Hygiene & Tropical Medicine London United Kingdom Scientific Computing Program Oswaldo Cruz Foundation Rio de Janeiro Brazil Health Information and Communication Institute Oswaldo Cruz Foundation Rio de Janeiro Brazil Scripps Institution of Oceanography University of California San Diego San Diego CA United States Health Innovation Laboratory Institute of Tropical Medicine Alexander von Humboldt Universidad Peruana Cayetano Heredia Lima Peru Department of Geography Federal University of Espírito Santo Vitória Brazil MRC Centre for Environment and Health Department of Epidemiology and Biostatistics Imperial College London London United Kingdom Statistics Program Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia

Background: Temperature and rainfall patterns are known to influence seasonal patterns of dengue transmission. However, the effect of severe drought and extremely wet conditions on the timing and intensity of dengue epidemics is poorly understood. In this study, we aimed to quantify the non-linear and delayed effects of extreme hydrometeorological hazards on dengue risk by level of urbanisation in Brazil using a spatiotemporal model. Methods: We combined distributed lag non-linear models with a spatiotemporal Bayesian hierarchical model framework to determine the exposure-lag-response association between the relative risk (RR) of dengue and a drought severity index. We fit the model to monthly dengue case data for the 558 microregions of Brazil between January, 2001, and January, 2019, accounting for unobserved confounding factors, spatial autocorrelation, seasonality, and interannual variability. We assessed the variation in RR by level of urbanisation through an interaction between the drought severity index and urbanisation. We also assessed the effect of hydrometeorological hazards on dengue risk in areas with a high frequency of water supply shortages. Findings: The dataset included 12 895 293 dengue cases reported between 2001 and 2019 in Brazil. Overall, the risk of dengue increased between 0–3 months after extremely wet conditions (maximum RR at 1 month lag 1·56 [95% CI 1·41–1·73]) and 3–5 months after drought conditions (maximum RR at 4 months lag 1·43 [1·22–1·67]). Including a linear interaction between the drought severity index and level of urbanisation improved the model fit and showed the risk of dengue was higher in more rural areas than highly urbanised areas during extremely wet conditions (maximum RR 1·77 [1·32–2·37] at 0 months lag vs maximum RR 1·58 [1·39–1·81] at 2 months lag), but higher in highly urbanised areas than rural areas after extreme drought (maximum RR 1·60 [1·33–1·92] vs 1·15 [1·08–1·22], both at 4 months lag). We also found the den

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Observation of the Magnonic Dicke Superradiant Phase Transition

arXiv

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arXiv 2024年

作者： Kim, Dasom Dasgupta, Sohail Ma, Xiaoxuan Park, Joong-Mok Wei, Hao-Tian Luo, Liang Doumani, Jacques Li, Xinwei Yang, Wanting Cheng, Di Kim, Richard H.J. Everitt, Henry O. Kimura, Shojiro Nojiri, Hiroyuki Wang, Jigang Cao, Shixun Bamba, Motoaki Hazzard, Kaden R.A. Kono, Junichiro Applied Physics Graduate Program Smalley–Curl Institute Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Ames National Laboratory AmesIA50011 United States Department of Physics and Astronomy Rice University HoustonTX77005 United States Department of Physics International Center of Quantum and Molecular Structures Materials Genome Institute Shanghai University Shanghai200444 China Department of Physics National University of Singapore 117551 Singapore Department of Physics and Astronomy Iowa State University AmesIA50011 United States Smalley–Curl Institute Rice University HoustonTX77005 United States DEVCOM Army Research Laboratory-South HoustonTX77005 United States Institute for Materials Research Tohoku University Sendai980-8577 Japan Department of Physics Yokohama National University Yokohama240-8501 Japan Department of Physics and Astronomy University of California DavisCA95616 United States Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States

Two-level atoms coupled with single-mode cavity photons are predicted to exhibit a quantum phase transition when the coupling strength exceeds a critical value, entering a phase in which atomic polarization and photonic field are finite even at zero temperature and without external driving. However, this phenomenon, the superradiant phase transition (SRPT), is forbidden by a no-go theorem due to the existence of the diamagnetic term in the Hamiltonian. Here, we present spectroscopic evidence for a magnonic SRPT in ErFeO3, where the role of the photonic mode (two-level atoms) in the photonic SRPT is played by an Fe3+ magnon mode (Er3+ spins). The absence of the diamagnetic term in the Fe3+–Er3+ exchange coupling ensures that the no-go theorem does not apply. Terahertz and gigahertz magnetospectroscopy experiments revealed the signatures of the SRPT – a kink and a softening, respectively, of two spin–magnon hybridized modes at the critical point. Copyright © 2024, The Authors. All rights reserved.

关键词： Phase transitions

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Zeeman polaritons as a platform for probing Dicke physics in condensed matter

arXiv

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arXiv 2024年

作者： Kritzell, T. Elijah Doumani, Jacques Asano, Tobias Yamada, Sota Tay, Fuyang Xu, Hongjing Yan, Han Katayama, Ikufumi Takeda, Jun Nevidomskyy, Andriy Nojiri, Hiroyuki Bamba, Motoaki Baydin, Andrey Kono, Junichiro Applied Physics Graduate Program Smalley-Curl Institute Rice University 6100 Main Street HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University 6100 Main Street HoustonTX77005 United States Department of Physics Yokohama National University 79-5 Tokiwadai Hodogaya-ku Kanagawa Yokohama240-8501 Japan Department of Physics and Astronomy Rice University 6100 Main Street HoustonTX77005 United States Smalley-Curl Institute Rice University 6100 Main Street HoustonTX77005 United States Institute for Multidisciplinary Sciences Yokohama National University 79-5 Tokiwadai Hodogaya-ku Kanagawa Yokohama240-8501 Japan Institute for Materials Research Tohoku University 2-1-1 Katahira Aoba-ku Miyagi Sendai980-8577 Japan Rice Advanced Materials Institute Rice University 6100 Main Street HoustonTX77005 United States Department of Materials Science and NanoEngineering Rice University 6100 Main Street HoustonTX77005 United States

The interaction of an ensemble of two-level atoms and a quantized electromagnetic field, described by the Dicke Hamiltonian, is an extensively studied problem in quantum optics. However, experimental efforts to explore similar physics in condensed matter typically employ bosonic matter modes (e.g., phonons, magnons, and plasmons) that are describable as simple harmonic oscillators, i.e., an infinite ladder of equally spaced energy levels. Here, we examine ultrastrong coupling between a coherent light mode and an ensemble of paramagnetic spins, a finite-multilevel system, in Gd3Ga5O12. The electron paramagnetic resonance of Gd3+ ions is tuned by a magnetic field into resonance with a Fabry–Pérot cavity mode, resulting in the formation of spin–photon hybrid states, or Zeeman polaritons. We observe that the light–matter coupling strength, measured through the vacuum Rabi splitting, decreases with increasing temperature, which can be explained by the temperature-dependent population difference between the lower and higher-energy states, a trait of a finite-level system. This finding demonstrates that a spin–boson system is more compatible with the Dicke model and has advantages over boson–boson systems for pursuing experimental realizations of phenomena predicted for ultrastrongly coupled light–matter hybrids. Copyright © 2024, The Authors. All rights reserved.

关键词： Phonons

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