Female breast cancer is a major cause of death in western countries. Several computer techniques have been developed to aid radiologists to improve their performance in the detection and diagnosis of breast abnormalit...
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With myriad information being generated from high-throughput experiments such as microarrays and sequencing technologies, an ever-increasing amount of data is being recorded and analyzed with the help of hierarchical ...
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With myriad information being generated from high-throughput experiments such as microarrays and sequencing technologies, an ever-increasing amount of data is being recorded and analyzed with the help of hierarchical ontologies, such as the gene ontology (GO). We have developed a novel framework- based on the well established foundations of information theory- that allows for the evaluation of new types of hypotheses. The framework, encapsulated in open biomedical ontology-based exploration and search (OBOES), has already been applied in the investigation of different kinds of questions. The resulting framework enables the new field of information theoretic ontology-based analysis. We have applied this framework to create methods to re-engineer ontologies, explore fundamental questions on the evolution of biological complexity, determine optimal ontology terms for bioinformatics analysis, and quantify the usefulness of biofluids as proxies for tissues/diseases. In each case, we found that our methods provide novel, significant findings. An open source Java implementation of OBOES is available at: http://***.
Electrochromic oxide films form the basis of smart windows, which are of much interest in forthcoming building technology and are able to provide energy efficiency and indoor comfort simultaneously. This paper introdu...
A methodology and algorithms for the detection of divergences of aircraft from their flight plans on the horizontal plane are presented. Deviations from the flight plan are often the result human error, such as miscom...
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ISBN:
(纸本)1563478196
A methodology and algorithms for the detection of divergences of aircraft from their flight plans on the horizontal plane are presented. Deviations from the flight plan are often the result human error, such as miscommunication between the pilot and the air traffic controller (ATC), situational awareness errors of the ATC, discrepancies between the mental picture of the ATC and his/her decision support tools, etc. The goal is to detect divergences due to these factors as early as possible and provide a timely warning. The difficulty is distinguishing these "important" divergences from generic deviations, due for example to local wind conditions. Here we develop algorithms for addressing this problem, inspired by methods from fault detection and isolation. The algorithms are tested on a detailed simulation of a Boeing 763-300 flying in a wind Held with realistic spatio-temporal correlation structure.
The recent technological advancements in biological research have allowed researchers to advance their knowledge of the domain far beyond expectations. The advent of easily accessible biological web databases such as ...
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This paper treats the output feedback H-2 control with regional pole placement condition. In general, this problem is a BMI problem which is difficult to be solved theoretically. The purpose of this paper is to propos...
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ISBN:
(纸本)9788995003848
This paper treats the output feedback H-2 control with regional pole placement condition. In general, this problem is a BMI problem which is difficult to be solved theoretically. The purpose of this paper is to propose an iterative method for obtaining a sub-optimal solution of the H-2 control problem with regional pole placement condition. The key idea of this paper is to employ a full-order observer-based controller. The proposed method produces a sequence of controllers which approaches to the unconstrained globally optimal H-2 controller while it satisfies the D-stability constraint. A numerical example shows the effectiveness of our method.
Extensible processors allow customization for an application by extending the core instruction set architecture. Extracting appropriate custom instructions is an important phase for implementing an application on an e...
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Background: The magnetoencephalograms (MEGs) are mainly due to the source currents. However, there is a significant contribution to MEGs from the volume currents. The structure of the anatomical surfaces, e.g., gray a...
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Background: The magnetoencephalograms (MEGs) are mainly due to the source currents. However, there is a significant contribution to MEGs from the volume currents. The structure of the anatomical surfaces, e.g., gray and white matter, could severely influence the flow of volume currents in a head model. This, in turn, will also influence the MEGs and the inverse source localizations. This was examined in detail with three different human head models. Methods: Three finite element head models constructed from segmented MR images of an adult male subject were used for this study. These models were: (1) Model 1: full model with eleven tissues that included detailed structure of the scalp, hard and soft skull bone, CSF, gray and white matter and other prominent tissues, (2) the Model 2 was derived from the Model 1 in which the conductivity of gray matter was set equal to the white matter, i.e., a ten tissuetype model, (3) the Model 3 consisted of scalp, hard skull bone, CSF, gray and white matter, i.e., a five tissue-type model. The lead fields and MEGs due to dipolar sources in the motor cortex were computed for all three models. The dipolar sources were oriented normal to the cortical surface and had a dipole moment of 100 μA meter. The inverse source localizations were performed with an exhaustive search pattern in the motor cortex area. A set of 100 trial inverse runs was made covering the 3 cm cube motor cortex area in a random fashion. The Model 1 was used as a reference model. Results: The reference model (Model 1), as expected, performed best in localizing the sources in the motor cortex area. The Model 3 performed the worst. The mean source localization errors (MLEs) of the Model 3 were larger than the Model 1 or 2. The contour plots of the magnetic fields on top of the head were also different for all three models. The magnetic fields due to source currents were larger in magnitude as compared to the magnetic fields of volume currents. Discussion: These results
In this paper we look at the serial concatenation of linear block codes with a rate-l recursive convolutional code (accumulator). In particular, we present results for extended Bose Chaudhuri Hocquenghem (eBCH) codes....
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ISBN:
(纸本)9783800729470
In this paper we look at the serial concatenation of linear block codes with a rate-l recursive convolutional code (accumulator). In particular, we present results for extended Bose Chaudhuri Hocquenghem (eBCH) codes. These codes offer low error floors, good performance and more flexible rate choices than product codes. Reduced complexity list decoding is used to decode the eBCH codes in order to maintain low decoding complexity.
In this article I deal with singularities of a rational B-Spline representation of the sphere. If just one rectangular parametric patch is used to form the whole sphere then two unwanted singularities arise. Those are...
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ISBN:
(纸本)809673055X
In this article I deal with singularities of a rational B-Spline representation of the sphere. If just one rectangular parametric patch is used to form the whole sphere then two unwanted singularities arise. Those are the two points lying on the axis of revolution and therefore during the rotation of the half circle through an angle of 360 degrees around the diameter they form two degenerate isoparametric curves in one parametric direction. Of course, such points are problematic for most applications in graphics and CAD design because in their vicinity existing numerical methods for curve/surface or surface/surface intersections fail to converge. To circumvent this I suggest to use at least three such parametric patches via trimmed surfaces to fully describe the boundary of the sphere preserving the Euler formula and geometric G2 continuity of the resulting solid.
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