Microarray gene expression datasets comprise of a large number of genes in contrast to a small number of samples, thus having a high dimension of variables. Analysis of microarray data can lead us to many useful concl...
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ISBN:
(纸本)9789881925275
Microarray gene expression datasets comprise of a large number of genes in contrast to a small number of samples, thus having a high dimension of variables. Analysis of microarray data can lead us to many useful conclusions. In many microarray data analyses, selecting a small subset of genes which are of significance for a particular type of disease is an important issue but selection of such genes become difficult due to many irrelevant genes and noisy genes. The process of gene selection helps to extract the most informative genes, which consequently aid to build a robust prediction model using those genes. In this study, we employ a hybrid Chemical Reaction Optimization (CRO) based filter-wrapper methodology, which uses an information gain gene ranking heuristic to simultaneously extract informative gene subsets and build robust cancer classification models. The performance of the proposed method was tested on three benchmark gene expression datasets obtained from the Kent Ridge Biomedical datasets collection and the LIBSVM data repository. CRO results demonstrate its capability to select relevant genes with high confidence in comparison to the results reported earlier.
作者：
Dutt, NikilRegazzoni, Carlo S.Rinner, BernhardYao, XinNikil Dutt (Fellow
IEEE) received the Ph.D. degree from the University of Illinois at Urbana–Champaign Champaign IL USA in 1989.""He is currently a Distinguished Professor of computer science (CS) cognitive sciences and electrical engineering and computer sciences (EECS) with the University of California at Irvine Irvine CA USA. He is a coauthor of seven books. His research interests include embedded systems electronic design automation (EDA) computer architecture distributed systems healthcare Internet of Things (IoT) and brain-inspired architectures and computing.""Dr. Dutt is a Fellow of ACM. He was a recipient of the IFIP Silver Core Award. He has received numerous best paper awards. He serves as the Steering Committee Chair of the IEEE/ACM Embedded Systems Week (ESWEEK). He is also on the steering organizing and program committees of several premier EDA and embedded system design conferences and workshops. He has served on the Editorial Boards for the IEEE Transactions on Very Large Scale Integration (VLSI) Systems and the ACM Transactions on Embedded Computing Systems and also previously served as the Editor-in-Chief (EiC) for the ACM Transactions on Design Automation of Electronic Systems. He served on the Advisory Boards of the IEEE Embedded Systems Letters the ACM Special Interest Group on Embedded Systems the ACM Special Interest Group on Design Automationt and the ACM Transactions on Embedded Computing Systems. Carlo S. Regazzoni (Senior Member
IEEE) received the M.S. and Ph.D. degrees in electronic and telecommunications engineering from the University of Genoa Genoa Italy in 1987 and 1992 respectively.""He is currently a Full Professor of cognitive telecommunications systems with the Department of Electrical Electronics and Telecommunication Engineering and Naval Architecture (DITEN) University of Genoa and a Co-Ordinator of the Joint Doctorate on Interactive and Cognitive Environments (JDICE) international Ph.D. course started initially as EU Erasmus Mundus Project and
Autonomous systems are able to make decisions and potentially take actions without direct human intervention, which requires some knowledge about the system and its environment as well as goal-oriented reasoning. In c...
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Autonomous systems are able to make decisions and potentially take actions without direct human intervention, which requires some knowledge about the system and its environment as well as goal-oriented reasoning. In computer systems, one can derive such behavior from the concept of a rational agent with autonomy (“control over its own actions”), reactivity (“react to events from the environment”), proactivity (“act on its own initiative”), and sociality (“interact with other agents”) as fundamental properties \n[1]\n. Autonomous systems will undoubtedly pervade into our everyday lives, and we will find them in a variety of domains and applications including robotics, transportation, health care, communications, and entertainment to name a few. \nThe articles in this month’s special issue cover concepts and fundamentals, architectures and techniques, and applications and case studies in the exciting area of self-awareness in autonomous systems.
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