It is being observed that the use of Internet of Medical Things (IoMT) in health sciences research grows as the technology and miniaturization of devices occur. Those devices often times suffer from several issues suc...
详细信息
Viral infections cause a large number of deaths worldwide. During the inflammatory process secondary to a viral infection, edema may appear, that is, fluid may accumulate in the interstitial tissue. computational mode...
详细信息
ISBN:
(纸本)9781728118680
Viral infections cause a large number of deaths worldwide. During the inflammatory process secondary to a viral infection, edema may appear, that is, fluid may accumulate in the interstitial tissue. computational modeling is a tool that can be used to understand this phenomenon better. This paper proposes a first-step model to describe the formation of viral cardiac edema. In particular, this paper presents a model that describes the increase in interstitial pressure during viral infections. Preliminary computational results show that the model can qualitatively reproduce results described in the literature.
Over the last few years, computer models have become valuable tools for the understanding of complex biological phenomena, such as the electric propagation on cardiac tissue. We have developed a Heart Simulator that m...
详细信息
In the last few years, there has been an increasing interest in the mathematical and computational modeling of the human immune system (HIS). In particular, the use of computational models is fundamental to understand...
详细信息
In this work we describe the initial implementation of a web-based tool for the automatic segmentation of cardiac Magnetic Resonance Images. The application uses an active contours algorithm called Snakes, which are a...
详细信息
In the last few years, there has been an increasing interest in the mathematical and computational modeling of the human immune system (HIS). In particular, the use of computational models is fundamental to understand...
详细信息
In the last few years, there has been an increasing interest in the mathematical and computational modeling of the human immune system (HIS). In particular, the use of computational models is fundamental to understand the HIS dynamics. The availability of computational models on which to do experiments and to test new hypothesis would accelerate our understanding of the HIS, allowing us to develop new drugs against many diseases. In this scenario we extended, in a previous work, a computational model of the HIS that represents the behavior of two of its cells, the B and T lymphocytes, in distinct situations. In this paper we present a parallel implementation of the model, developed in order to reduce the computational time needed in the simulations. We also describe the techniques used in the implementation of the parallel model, evaluates its performance, and discuss the initial results that have been obtained.
The cardiac Monodomain model is a mathematical model extensively used in studies of propagation of bioelectric wavefronts in the heart. To be able to use the model for complex and large cardiac simulations, such as th...
详细信息
The cardiac Monodomain model is a mathematical model extensively used in studies of propagation of bioelectric wavefronts in the heart. To be able to use the model for complex and large cardiac simulations, such as the case of whole heart and 3D simulations, some parameters of the model that are known to physiologically vary in space, such as the intracellular conductivity, are traditionally kept constant at effective values. These effective values can be obtained via a mathematical procedure called homogenization. In this work we revisit the classical homogenized monodomain formulation to evaluate its ability to reproduce the situation of low gap junctional coupling. This situation arises in many pathological conditions such as during ischemia. Our numerical results suggest some limitations of the homogenized cardiac Monodomain model under these conditions in terms of computed conduction velocity and Action Potential waverforms.
暂无评论