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Mechanical and physical properties of unsaturated polyester reinforced kenaf core fiber with hybrid cellulose nanocrystal (CNC) and graphene Nanoplatelet(GNP) nanofillers

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Materials Today: Proceedings 2023年 75卷 163-168页

作者： Izzati Mustapha, Nur Mohamed, Mazlan Bashree Abu Bakar, Mohamad Ahmad Sobri, Sharizal Faculty of Bioengineering & Technology University Malaysia Kelantan Jeli Kelantan 17600 Malaysia

In this study, the exploration of kenaf core fiber (KCF) was done by incorporating into unsaturated polyester (UPE) as to keep the environment sustain and also due to its potential properties which are good mechanical properties, low cost and importantly massively abundant. The hybridization technique also were applied with the incorporation of total loading level of 3 wt% Cellulose nanocrystal (CNC) and graphene nanoplatelet (GNP) into UPE-KCF bio-composite as to support and provide better performance of UPE bio-composite. In revealing the effect of nanofillers utilization towards mechanical and physical properties of UPE-KCF bio-composite, the fabrication of UPE-KCF/CNC/GNP bio-composite were successfully done by using hand lay-up technique and hot compression moulding. The samples were characterized through tensile and flexural test for mechanical analysis and water absorption for physical analysis. Morphology characterization also was done to support the result. The results showed the incorporation of KCF had contributed for the slightly improvement in tensile modulus while both inclusion of nanofillers help the single reinforcement bio-composite to enhance flexural strength and modulus up to 48.2% and 84.21% respectively. The addition of 2 wt% GNP also positively influence physical properties showed by the least percentage of water absorption. © 2022

关键词： Cellulose

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Green synthesis of silver nanoparticles using carob leaf extract: Characterization and analysis of toxic effects in model organism Galleria mellonella L. (The greater wax moth)

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Environmental Science and Pollution Research 2024年第47期31卷 57778-57788页

作者： Andırın, Aslıhan Yaycı, Nur Dudu Idikut, Murat Kara, Ayse Tuncsoy, Mustafa Tuncsoy, Benay Ozalp, Pınar Department of Bioengineering Faculty of Engineering Adana Alparslan Turkes Science and Technology University Adana Turkey Department of Biology Faculty of Science and Letter Cukurova University Adana Turkey

Silver nanoparticles (Ag NPs) have been used in many studies due to their inhibitory properties on microorganisms such as bacteria and viruses. In recent years, due to global problems such as environmental pollution, the green synthesis (biosynthesis) method is frequently preferred because it is simple and low cost and does not require the use of toxic substances. The aim of this study is to synthesize silver nanoparticles (Ag NPs) from Ceratonia siliqua L. leaves and investigate their antioxidant and immunotoxic properties using Galleria mellonella last instar larvae. The UV spectrophotometer, TEM, XRD and FTIR measurements were used to characterize the Ag NPs. In this study, it was determined that the effects on antioxidant enzyme activities (SOD, CAT, GPx, GST), acetylcholinesterase (AChE) and total hemocyte count (THC) as well as phenoloxidase activity determine their effect on antioxidant defence and the immune system in model organism G. mellonella larvae. We observed that green synthesized Ag NPs accumulate in the midgut of the larvae and led to the increasing of CAT and SOD activities. GST and AChE activities were increased in the fat body of the larvae;otherwise, it was decreased in the midgut. Moreover, increases were found in THC and phenoloxidase activity. Consequently, green synthesized silver nanoparticles led to oxidative stress and immunotoxic effects on G. mellonella larvae. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.

关键词： Silver nanoparticles

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Scalable fabrication,compartmentalization and applications of living microtissues

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Bioactive Materials 2023年第1期19卷 392-405页

作者： Maik Schot Nuno Araújo-Gomes Bas van Loo Tom Kamperman Jeroen Leijten Department of Developmental Bioengineering Faculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522NBEnschedethe Netherlands

Living microtissues are used in a multitude of applications as they more closely resemble native tissue physiology,as compared to 2D *** are typically composed of a combination of cells and materials in varying combinations,which are dictated by the applications’design *** applications range wide,from fundamental biological research such as differentiation studies to industrial applications such as cruelty-free meat ***,their translation to industrial and clinical settings has been hindered due to the lack of scalability of microtissue production *** microfluidic processes provide an opportunity to overcome this limitation as they offer higher throughput production rates as compared to traditional batch techniques,while maintaining reproducible control over microtissue composition and *** this review,we provide a comprehensive overview of the current approaches to engineer microtissues with a focus on the advantages of,and need for,the use of continuous processes to produce microtissues in large ***,an outlook is provided that outlines the required developments to enable large-scale microtissue fabrication using continuous processes.

关键词： Tissue engineering Micromaterials Microfluidics Upscaling Clinical translation Industrial translation

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IMPACT OF INTENSIVE AND SEMI-INTENSIVE FARMING ON HISTOLOGICAL FEATURES AND CULINARY PROPERTIES OF COMMON CARP (CYPRINUS CARPIO L.) FILLETS

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Acta Universitatis Cibiniensis - Series E: Food technology 2024年第2期28卷 207-220页

作者： Eljasik, Piotr Sobczak, Malgorzata Lisiecki, Slawomir Sadowski, Jacek Panicz, Remigiusz Department of Meat Science Faculty of Food Science and Fisheries West Pomeranian University of Technology Szczecin Poland Department of Aquatic Bioengineering and Aquaculture Faculty of Food Science and Fisheries West Pomeranian University of Technology Szczecin Poland

Eco-intensification of freshwater aquaculture production is considered one of the solutions to achieve global food security. However, intensification of the production may come with product quality trade-offs, which are unlikely to be accepted by modern consumers. The aim of this study was to evaluate impact of intensive cage farming and typical semi-intensive pond culture on culinary and histological characteristics of common carp (Cyprinus carpio L.) fillets. In intensive cage culture common carp were fed formulated feed for 60 days, while in semi-intensive pond farming fish utilised natural food and supplementary grains (triticale) for 90 days to achieve similar weight. Next, fish were sacrificed, filleted and quality of fillets, i.e. pH, colour, histology of muscle tissue, texture and sensory properties were assessed. The results showed that intensive cage culture, because of constant water flow, contributed to muscle development through hypertrophy mechanism and resulted with higher number of large muscle fibers (over 60 μm in diameter) compared to semi-intensive pond farming. The differences in histology of muscle tissue were correlated with sensory characteristics of fillets, but not with texture instrumental analysis. Appearance (colour) and taste of the fillets of common carp from semi-intensive pond farming was more attractive from consumers' perspective, especially that no negative features, such as off-flavour were noted compared to intensive cage culture. © 2024 Piotr Eljasik et al., published by Sciendo.

关键词： Muscle

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A comparison study on hydrophobic and hydrophilic-mixed matrix membranes for diethanolamine removal

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Materials Research Innovations 2025年第4期29卷 262-268页

作者： Rahman, Sunarti Abd Ndia Ntone, Ellora Priscille Alagu, Divyameena Rajeswaran, Dharshini Deepa Shoparwe, Noor Fazliani Mun, Serene Lock Sow Lee, Yeu Yee Faculty of Chemical & Process Engineering Technology Universiti Malaysia Pahang AL- Sultan Abdullah Gambang Malaysia Faculty of Bioengineering and Technology Universiti Malaysia Kelantan Kelantan Kota Bharu Malaysia Department of Chemical Engineering Universiti Teknologi PETRONAS Seri Iskandar Malaysia Kuching Malaysia

This study systematically compares Polyvinylidene fluoride (PVDF) and Polysulfone (PSf) mixed-matrix membranes (MMMs) modified with graphene oxide (GO) for diethanolamine (DEA) removal. PVDF and PSf exhibit distinct interactions with GO due to their inherent hydrophobic and hydrophilic properties, respectively, influencing membrane performance. Membranes were fabricated using the phase inversion method and characterized by Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), and Contact Angle (CA) analysis. Performance testing revealed superior water permeability and DEA rejection for PSf/GO membranes. The PSf/GO-0.5 membrane achieved 91.04% DEA rejection and 47.45 L/m²·h·bar water permeability, outperforming PVDF/GO-0.5, which demonstrated 78.53% DEA rejection and 28.32 L/m²·h·bar water permeability. While GO improved membrane performance, excessive loading caused pore clogging, reducing effectiveness. This study highlights the potential of hydrophilic PSf/GO membranes for efficient amine removal, offering valuable insights for wastewater treatment applications. © 2024 Informa UK Limited, trading as Taylor & Francis Group.

关键词： Fourier transform infrared spectroscopy

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Computer Aided Music Visualization Teaching Model Based on Emotional Feature Detection

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Computer-Aided Design and Applications 2024年第S10期21卷 46-60页

作者： Deng, Yu He, Jie Hu, Linyuan Faculty of Education and Arts College of Arts and Science Hubei Normal University Hubei Huangshi435109 China Shool of Computer Science and Technology Wuhan University of Bioengineering Hubei Wuhan430415 China School of Music Wuhan University of Bioengineering Hubei Wuhan430415 China

Computer-aided instruction (CAI) technology has an important influence in the stage of music education and teaching, no matter in educational concept, educational content or curriculum form. With people paying more and more attention to music education, the application of CAI in music teaching has become a hot spot in today's education. This article presents a computer-aided visual music instructional model based on emotional feature detection. In this model, the graph-convolution network (GCN) is used to identify the emotional characteristics of music, and the emotional information in music is extracted and transformed into a visual form to help students better understand and feel the emotional expression in music. The application of this model can transform the audio characteristics of music works into visual images through image processing technology, so that students can better understand the emotional characteristics of music works. Moreover, the flexibility and operability of CAI system also provide more possibilities and creativity for music teaching. The model proposed in this article has a wide application prospect and can provide an effective auxiliary tool for music teaching and music emotion research. © 2024 U-turn Press LLC.

关键词： Music

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Mechanical and physical properties of unsaturated polyester reinforced kenaf core fiber with hybrid cellulose nanocrystal (CNC) and graphene Nanoplatelet(GNP) nanofillers

Mechanical and physical properties of unsaturated polyester ...

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作者： Izzati Mustapha, Nur Mohamed, Mazlan Bashree Abu Bakar, Mohamad Ahmad Sobri, Sharizal Faculty of Bioengineering & Technology University Malaysia Kelantan Jeli Kelantan17600 Malaysia

关键词： Cellulose

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Efficiency Prediction of E. Conferta in Natural-Sensitized Dye-Sensitized Solar Cells Using k-Nearest Neighbors 1

Efficiency Prediction of E. Conferta in Natural-Sensitized D...

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1st IEEE International Conference on Communication Engineering and Emerging Technologies, ICoCET 2024

作者： Binti Jaafar, Haryati Binti Jaafar, Hidayani Binti Azman Fauzi, Azlin Natasha Universiti Malaysia Perlis Faculty of Electrical Engineering & Technology Department of Mechatronic Perlis Arau Malaysia Universiti Malaysia Kelantan Faculty of Bioengineering and Technology Jeli Campus Kelantan Jeli Malaysia

ISBN: (纸本)9798331504144

Dye-Sensitized Solar Cells (DSSCs) have gained attention as a potential replacement. Recently, natural-sensitized DSSCs have been noted for their low cost and environmental friendliness. However, a significant drawback of natural dyes is their lower efficiency compared to synthetic ones. This has led to extensive research into DSSC characteristics, with Electrochemical Impedance Spectroscopy (EIS) being a prominent focus. Despite its importance, analyzing EIS data can be complex and time-consuming. To address this, machine learning techniques were employed in this study to predict the highest efficiency based on various samples. E. conferta was used as a sensitizer for the DSSCs, and different amounts of Nb-doped TiO2 were tested to create diverse samples. k-Nearest Neighbors (kNN) was utilized to identify the sample with the highest efficiency, revealing that DSSCs with 1.0 wt% Nb-doped TiO2 achieved the highest efficiency, with a prediction accuracy of 90%. To validate the kNN results, manual measurements were conducted, and the findings, presented in Nyquist plots, confirmed that kNN predictions are as reliable as manual measurements for predicting efficiency. © 2024 IEEE.

关键词： Titanium dioxide

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Design, molecular characterization and therapeutic investigation of a novel CCR8 peptide antagonist that attenuates acute liver injury by inhibiting infiltration and activation of macrophages

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Acta Pharmaceutica Sinica B 2025年第4期15卷 2114-2133页

作者： Geervliet, Eline Arora, Sahil Donohue, Dagmara Antonio de Albuquerque Pinheiro, Carlos Terstappen, Leon W.M.M. Schasfoort, Richard Paez, Julieta Kumar, Raj Bansal, Ruchi Personalized Diagnostics and Therapeutics Department of Bioengineering Technologies Technical Medical Centre Faculty of Science and Technology University of Twente Netherlands Institute of Molecular Pathobiochemistry Experimental Gene Therapy and Clinical Chemistry RWTH University Hospital Aachen Germany Department of Pharmaceutical Sciences and Natural Products School of Health Sciences Central University of Punjab India Developmental BioEngineering Department of Bioengineering Technologies Technical Medical Centre Faculty of Science and Technology University of Twente Netherlands

During liver injury, intrahepatic macrophage compartment is augmented by circulating monocytes that infiltrate the liver driven by C–C motif chemokine ligand/C–C motif chemokine receptor (CCL/CCR) axis including CCL1‒CCR8 axis, thereby contributing to liver inflammation. Numerous small molecular receptor antagonists, including R243, have been developed for targeting CCR8;however, these agents face challenges in clinical translation, potentially attributed to their poor pharmacokinetic profiles, lack of target specificity, and potential adverse effects. In this study, we designed four CCR8 antagonizing peptides (AP8i-AP8iv) and performed molecular characterization in-silico and therapeutic investigation in-vitro and in-vivo. Based on in-silico docking, molecular dynamic simulation using homology build model and in-vitro (competitive) binding studies, AP8ii (YEWRFYHG) evidenced highly favorable and selective interactions at the CCR8-active site. AP8ii inhibited CCL1-driven chemotaxis and LPS/IFNγ-induced pro-inflammatory activation of monocytes-macrophages in-vitro. In a CCl₄-induced acute liver injury mouse model, AP8ii treatment decreased intrahepatic infiltration of circulating monocytes. Moreover, AP8ii reduced liver inflammation, as indicated by decreased F4/80, IL6 and iNOS expression, diminished ALT levels, and attenuated fibrosis, as indicated by reduced collagen-I expression. In conclusion, we report a novel CCR8-antagonizing peptide that inhibited CCL1-driven intrahepatic monocytes infiltration and differentiation into pro-inflammatory phenotype, consequently ameliorating liver inflammation and fibrogenesis in an acute liver injury mouse model. © 2025 The Authors

关键词： CCL1‒CCR8 axis CCR8 antagonizing peptide In silico molecular docking In vitro chemotaxis In vivo acute liver injury Intrahepatic monocyte infiltration and differentiation Liver inflammation

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Cowpea NAC1/NAC2 transcription factors improve growth and tolerance to drought and heat in transgenic cowpea through combined activation of photosynthetic and antioxidant mechanisms

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Journal of Integrative Plant Biology 2023年第1期65卷 25-44页

作者： Richa Srivastava Yuriko Kobayashi Hiroyuki Koyama Lingaraj Sahoo Department of Biosciences and Bioengineering Indian Institute of Technology Guwahati Guwahati Assam 781039 India Faculty of Applied Biological Sciences Gifu University 1-1 YanagidoGifu 501-1193Japan

NAC(NAM/ATAF1/2/CUC2)transcription factors are central switches of growth and stress responses in ***,unpredictable interspecies conservation of function and regulatory targets makes the well-studied NAC orthologs inapt for pulse *** knowledge of suitable NAC candidates in hardy pulses like cowpea(Vigna unguiculata(L.)Walp.)is still in infancy,hence warrants immediate biotechnological ***,we showed that overexpression of two native NAC genes(VuNAC1and VuNAC2)promoted germinative,vegetative,and reproductive growth and conferred multiple abiotic stress tolerance in a commercial cowpea *** transgenic lines displayed increased leaf area,thicker stem,nodule-rich denser root system,early flowering,higher pod production(~3.2-fold and~2.1-fold),and greater seed weight(10.3%and 6.0%).In contrast,transient suppression of VuNAC1/2 caused severe growth retardation and flower *** overexpressor lines showed remarkable tolerance to major yielddeclining terminal stresses,such as drought,salinity,heat,and cold,and recovered growth and seed production by boosting photosynthetic activity,water use efficiency,membrane integrity,Na^(+)/K^(+)homeostasis,and antioxidant *** comparative transcriptome study indicated consolidated activation of genes involved in chloroplast development,photosynthetic complexes,cell division and expansion,cell wall biogenesis,nutrient uptake and metabolism,stress response,abscisic acid,and auxin *** their orthologs,VuNAC1/2 direct synergistic transcriptional tuning of stress and developmental signaling to avoid unwanted *** overexpression governs the favorable interplay of photosynthesis and reactive oxygen species regulation to improve stress recovery,nutritional sufficiency,biomass,and *** unconventional balance of strong stress tolerance and agronomic quality is useful for translational crop research and molecular breeding of pulses.

关键词： cowpea enhanced photosynthetic activity improved growth improved yield legume genetic engineering multiple stress tolerance NAC transcription factor VuNAC

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