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arXiv 2023年

作者： Eisenmann, M. Reinke, A. Weru, V. Tizabi, M.D. Isensee, F. Adler, T.J. Ali, S. Andrearczyk, V. Aubreville, M. Baid, U. Bakas, S. Balu, N. Bano, S. Bernal, J. Bodenstedt, S. Casella, A. Cheplygina, V. Daum, M. de Bruijne, M. Depeursinge, A. Dorent, R. Egger, J. Ellis, D.G. Engelhardt, S. Ganz, M. Ghatwary, N. Girard, G. Godau, P. Gupta, A. Hansen, L. Harada, K. Heinrich, M. Heller, N. Hering, A. Huaulmé, A. Jannin, P. Kavur, A.E. Kodym, O. Kozubek, M. Li, J. Li, H. Ma, J. Martín-Isla, C. Menze, B. Noble, A. Oreiller, V. Padoy, N. Pati, S. Payette, K. Rädsch, T. Rafael-Patiño, J. Bawa, V. Singh Speidel, S. Sudre, C.H. van Wijnen, K. Wagner, M. Wei, D. Yamlahi, A. Yap, M.H. Yuan, C. Zenk, M. Zia, A. Zimmerer, D. Aydogan, D. Bhattarai, B. Bloch, L. Brüngel, R. Cho, J. Choi, C. Dou, Q. Ezhov, I. Friedrich, C.M. Fuller, C. Gaire, R.R. Galdran, A. Faura, Á. García Grammatikopoulou, M. Hong, S. Jahanifar, M. Jang, I. Kadkhodamohammadi, A. Kang, I. Kofler, F. Kondo, S. Kuijf, H. Li, M. Luu, M. Martinčič, T. Morais, P. Naser, M.A. Oliveira, B. Owen, D. Pang, S. Park, J. Park, S. Plotka, S. Puybareau, E. Rajpoot, N. Ryu, K. Saeed, N. Shephard, A. Shi, P. Štepec, D. Subedi, R. Tochon, G. Torres, H.R. Urien, H. Vilaça, J.L. Wahid, K.A. Wang, H. Wang, J. Wang, L. Wang, X. Wiestler, B. Wodzinski, M. Xia, F. Xie, J. Xiong, Z. Yang, S. Yang, Y. Zhao, Z. Maier-Hein, K. Jäger, P.F. Kopp-Schneider, A. Maier-Hein, L. Heidelberg Germany Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Germany Heidelberg Germany School of Computing Faculty of Engineering and Physical Sciences University of Leeds Leeds United Kingdom Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Radiology University of Washington SeattleWA United States Department of Computer Science University College London London United Kingdom Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Biomedical Imaging Group Rotterdam Department of Radiology and Nuclear Medicine Erasmus MC Rotterdam Netherlands Department of Computer Science University of Copenhagen Copenhagen Denmark Sierre Switzerland Harvard Medical School Brigham and Women’s Hospital BostonMA United States School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom Essen Germany University of Nebraska Medical Center OmahaNE United States Department of Internal Medicine III Heidelberg University Hospital Heidelberg Germany Neurobiology Research Unit Copenhagen University Hospital Rigshospitalet C

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and postprocessing (66%). The "typical" lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work. © 2023, CC BY.

关键词： Benchmarking

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Space QUEST mission proposal: Experimentally testing decoherence due to gravity

arXiv

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arXiv 2017年

作者： Joshi, Siddarth Koduru Pienaar, Jacques Ralph, Timothy C. Cacciapuoti, Luigi McCutcheon, Will Rarity, John Giggenbach, Dirk Lim, Jin Gyu Makarov, Vadim Fuentes, Ivette Scheidl, Thomas Beckert, Erik Bourennane, Mohamed Bruschi, David Edward Cabello, Adan Capmany, Jose Carrasco-Casado, Alberto Diamanti, Eleni Dusek, Miloslav Elser, Dominique Gulinatti, Angelo Hadfield, Robert H. Jennewein, Thomas Kaltenbaek, Rainer Krainak, Michael A. Lo, Hoi-Kwong Marquardt, Christoph Milburn, Gerard Peev, Momtchil Poppe, Andreas Pruneri, Valerio Renner, Renato Salomon, Christophe Skaar, Johannes Solomos, Nikolaos Stipčević, Mario Torres, Juan P. Toyoshima, Morio Villoresi, Paolo Walmsley, Ian Weihs, Gregor Weinfurter, Harald Zeilinger, Anton Zukowski, Marek Ursin, Rupert Institute for Quantum Optics and Quantum Information Austrian Academy of Sciences Boltzmanngasse 3 ViennaA-1090 Austria Centre for Quantum Computation & Communication Technology Department of Physics University of Queensland St LuciaQLD4072 Australia European Space Agency Keplerlaan 1 - P.O. Box 299 AG Noordwijk ZH2200 Netherlands Department of Electrical and Electronic Engineering University of Bristol Merchant Venturers Building Woodland Road BristolBS8 1UB United Kingdom German Aerospace Center Institute of Communications and Navigation Muenchner Strasse 20 Wessling82234 Germany Institute for Quantum Computing Department of Electrical and Computer Engineering University of Waterloo WaterlooONN2L 3G1 Canada Institute for Quantum Computing Department of Physics and Astronomy University of Waterloo WaterlooONN2L 3G1 Canada Precision Engineering Department Fraunhofer IOF Albert-Einstein-Straße 7 Jena07745 Germany Physics department Stockholm University Albanova universitetscentrum Universitetsvägen 10 Stockholm114 18 Sweden York Centre for Quantum Technologies Department of Physics University of York HeslingtonYO10 5DD United Kingdom University of Seville SevillaE-41012 Spain iTEAM Research Institute Universitat Politcnica de Valencia Valencia46022 Spain 4-2-1 Nukui-Kitamachi Koganei Tokyo184-8795 Japan CNRS Universite Pierre et Marie Curie Paris75005 France Department of Optics Faculty of Science Palacky University 17. Iistopadu 12 Olomouc772 00 Czech Republic Max Planck Institute for the Science of Light Bldg. 24 Günther-Scharowsky Str. 1 ErlangenD-91058 Germany Piazza Leonardo da Vinci 32 Milano20133 Italy School of Engineering University of Glasgow GlasgowG12 8LT United Kingdom Vienna Center of Quantum Science and Technology Faculty of Physics University of Vienna Boltzmanngasse 5 ViennaA-1090 Austria NASA Goddard Space Flight Center GreenbeltMD20771 United States Center for Quantum Information and Quantum Con

Models of quantum systems on curved space-times lack sufficient experimental verification. Some speculative theories suggest that quantum properties, such as entanglement, may exhibit entirely different behavior to purely classical systems. By measuring this effect or lack thereof, we can test the hypotheses behind several such models. For instance, as predicted by Ralph and coworkers [T C Ralph, G J Milburn, and T Downes, Phys. Rev. A, 79(2):22121, 2009;T C Ralph and J Pienaar, New Journal of Physics, 16(8):85008, 2014], a bipartite entangled system could decohere if each particle traversed through a different gravitational field gradient. We propose to study this effect in a ground to space uplink scenario. We extend the above theoretical predictions of Ralph and coworkers and discuss the scientific consequences of detecting/failing to detect the predicted gravitational decoherence. We present a detailed mission design of the European Space Agency's (ESA) Space QUEST (Space - Quantum Entanglement Space Test) mission, and study the feasibility of the mission scheme. Copyright © 2017, The Authors. All rights reserved.

关键词： Quantum entanglement

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Metalla-Carbaporphyrinoids Consisting of an Acyclic N-Confused Tetrapyrrole Analogue Served as Stable Near-Infrared-II Dyes

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Angewandte Chemie 2024年第23期136卷

作者： Dr. Biju Basumatary Hidetoshi Tsuruda Prof. Dr. Dariusz W. Szczepanik Jiyeon Lee Jaehyeok Ryu Dr. Shigeki Mori Kyo Yamagata Prof. Dr. Takayuki Tanaka Dr. Atsuya Muranaka Prof. Masanobu Uchiyama Prof. Dr. Jiwon Kim Prof. Dr. Masatoshi Ishida Prof. Dr. Hiroyuki Furuta Department of Applied Chemistry Graduate School of Engineering Kyushu University Fukuoka 819-0395 Japan Department of Theoretical Chemistry Jagiellonian University Faculty of Chemistry Gronostajowa 2 30-387 Krakow Poland School of Integrated Technology College of Computing Integrated Science and Engineering Division Underwood International College Integrative Biotechnology and Translational Medicine Graduate School Yonsei University Incheon 21983 Korea Advanced Research Support Center Ehime University Matsuyama 790-8577 Japan Department of Molecular Engineering Graduate School of Engineering Kyoto University Nishikyo-ku Kyoto 615-8195 Japan Molecular Structure Characterization Unit RIKEN Center for Sustainable Resource Science 2-1 Hirosawa Wako Saitama 351-0198 Japan Graduate School of Pharmaceutical Sciences The University of Tokyo Tokyo 113-0033 Japan Department of Chemistry Graduate School of Sciences Tokyo Metropolitan University Hachioji 192-0397 Japan

We present herein the synthesis of novel pseudo -metalla-carbaporphyrinoid species ( 1M : M=Pd and Pt) achieved through the inner coordination of palladium(II) and platinum(II) with an acyclic N-confused tetrapyrrin analogue. Despite their tetrapyrrole frameworks being small, akin to well-known porphyrins, these species exhibit an unusually narrow HOMO–LUMO gap, resulting in an unprecedentedly low-energy absorption in the second near-infrared (NIR-II) region. Density functional theory (DFT) calculations revealed unique d π -p π -conjugated electronic structures involving the metal d π -ligand p π hybridized molecular orbitals of 1M . Magnetic circular dichroism (MCD) spectroscopy confirmed distinct electronic structures. Remarkably, the complexes feature an open-metal coordination site in the peripheral NN dipyrrin site, forming hetero-metal complexes ( 1Pd-BF 2 and 1Pt-BF 2 ) through boron difluoride complexation. The resulting hetero metalla-carbaporphyrinoid species displayed further redshifted NIR-II absorption, highly efficient photothermal conversion efficiencies ( η ; 62–65 %), and exceptional photostability. Despite the challenges associated with the theoretical and experimental assessment of d π -p π -conjugated metalla-aromaticity in relatively larger (more than 18π electrons) polycyclic ring systems, these organometallic planar tetrapyrrole systems could serve as potential molecular platforms for aromaticity-relevant NIR-II dyes.

关键词： porphyrinoid N-confusion near-infrared photothermal conversion metalla-(anti)aromaticity

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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Optimization of laser-driven quantum beam generation and the applications with artificial intelligence

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Physics of Plasmas 2024年第5期31卷

作者： Kuramitsu, Y. Taguchi, T. Nikaido, F. Minami, T. Hihara, T. Suzuki, S. Oda, K. Kuramoto, K. Yasui, T. Abe, Y. Ibano, K. Takabe, H. Chu, C.M. Wu, K.T. Woon, W.Y. Chen, S.H. Jao, C.S. Chen, Y.C. Liu, Y.L. Morace, A. Yogo, A. Arikawa, Y. Kohri, H. Tokiyasu, A. Kodaira, S. Kusumoto, T. Kanasaki, M. Asai, T. Fukuda, Y. Kondo, K. Kiriyama, H. Hayakawa, T. Tanaka, S.J. Isayama, S. Watamura, N. Suzuki, H. Kumar, H.S. Ohnishi, N. Pikuz, T. Filippov, E. Sakai, K. Yasuhara, R. Nakata, M. Ishikawa, R. Hoshi, T. Mizuta, A. Bolouki, N. Saura, N. Benkadda, S. Koenig, M. Hamaguchi, S. Graduate School of Engineering Osaka University 2-1 Yamadaoka Osaka Suita565-0871 Japan Institute of Laser Engineering Osaka University 2-6 Yamadaoka Osaka Suita565-0871 Japan 8-1-7 Umemidai Kyoto Kizugawa619-0215 Japan Department of Physics National Central University No. 300 Jhongda Rd. Taoyuan Jhongli320 Taiwan Department of Physics National Cheng Kung University Tainan701 Taiwan National Center for High-Performance Computing National Applied Research Laboratories Tainan City711010 Taiwan Institute of Space and Plasma Sciences National Cheng Kung University Tainan701 Taiwan Research Center for Nuclear Physics Osaka University 10-1 Mihogaoka Osaka Ibaraki567-0047 Japan Research Center for Accelerator and Radioisotope Science Tohoku University 1-2-1 Mikamine Taihaku-ku Miyagi Sendai982-0826 Japan Inage Chiba263-8555 Japan Graduate School of Maritime Sciences Kobe University Kobe658-0022 Japan Department of Physical Sciences Aoyama Gakuin University 5-10-1 Fuchinobe Kanagawa Sagamihara252-5258 Japan Department of Advanced Environmental Science and Engineering Kyushu University 6-1 Kasuga-Kohen Fukuoka Kasuga816-8580 Japan Graduate School of Information Science and Technology Osaka University 2-1 Yamadaoka Suita565-0871 Japan Department of Aerospace Engineering Tohoku University 6-6-01 Aramakiazaaoba Aoba-ku Sendai980-8579 Japan Institute for Open and Transdisciplinary Research Initiatives Osaka University 2-1 Yamadaoka Osaka Suita565-0871 Japan Villamayor Salamanca37185 Spain National Institute for Fusion Science 322-6 Oroshicho Gifu Toki509-5292 Japan Faculty of Arts and Sciences Komazawa University 1-23-1 Komazawa Setagaya-ku Tokyo154-8525 Japan Astrophysical Big Bang Laboratory RIKEN Saitama Wako351-0198 Japan Department of Plasma Physics and Technology Faculty of Science Masaryk University Kotlářská 2 Brno611 37 Czech Republic Aix-Marseille Université CNRS PIIM UMR 7345 Marseille France LULI CN

We have investigated space and astrophysical phenomena in nonrelativistic laboratory plasmas with long high-power lasers, such as collisionless shocks and magnetic reconnections, and have been exploring relativistic regimes with intense short pulse lasers, such as energetic ion acceleration using large-area suspended graphene. Increasing the intensity and repetition rate of the intense lasers, we have to handle large amounts of data from the experiments as well as the control parameters of laser beamlines. Artificial intelligence (AI) such as machine learning and neural networks may play essential roles in optimizing the laser and target conditions for efficient laser ion acceleration. Implementing AI into the laser system in mind, as the first step, we are introducing machine learning in ion etch pit analyses detected on plastic nuclear track detectors. Convolutional neural networks allow us to analyze big ion etch pit data with high precision and recall. We introduce one of the applications of laser-driven ion beams using AI to reconstruct vector electric and magnetic fields in laser-produced turbulent plasmas in three dimensions. © 2024 Author(s).

关键词： Ions

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Input optics systems of the KAGRA detector during O3GK (vol 2023, 023F01, 2023)

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PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS 2023年第5期2023卷

作者： Akutsu, T. Ando, M. Arai, K. Arai, Y. Araki, S. Araya, A. Aritomi, N. Asada, H. Aso, Y. Bae, S. Bae, Y. Baiotti, L. Bajpai, R. Barton, M. A. Cannon, K. Cao, Z. Capocasa, E. Chan, M. Chen, C. Chen, K. Chen, Y. Chiang, C-I Chu, H. Chu, Y-K Eguchi, S. Enomoto, Y. Flaminio, R. Fujii, Y. Fujikawa, Y. Fukunaga, M. Fukushima, M. Furuhata, T. Gao, D. Ge, G-G Ha, S. Hagiwara, A. Haino, S. Han, W-B Hasegawa, K. Hattori, K. Hayakawa, H. Hayama, K. Himemoto, Y. Hiranuma, Y. Hirata, N. Hirose, E. Hong, Z. Hsieh, B-H Huang, G-Z Huang, H-Y Huang, P. Huang, Y-C Huang, Y-J Hui, D. C. Y. Ide, S. Ikenoue, B. Imam, S. Inayoshi, K. Inoue, Y. Ioka, K. Ito, K. Itoh, Y. Izumi, K. Jeon, C. Jin, H-B Jung, K. Jung, P. Kaihotsu, K. Kajita, T. Kakizaki, M. Kamiizumi, M. Kanbara, S. Kanda, N. Kang, G. Kataoka, Y. Kawaguchi, K. Kawai, N. Kawasaki, T. Kim, C. Kim, J. Kim, J. C. Kim, Ws Kim, Y-M Kimura, N. Kita, N. Kitazawa, H. Kojima, Y. Kokeyama, K. Komori, K. Kong, A. K. H. Kotake, K. Kozakai, C. Kozu, R. Kumar, R. Kume, J. Kuo, C. Kuo, H-S Kuromiya, Y. Kuroyanagi, S. Kusayanagi, K. Kwak, K. Lee, H. K. Lee, H. W. Lee, R. Leonardi, M. Li, K. L. Lin, L. C-C Lin, C-Y Lin, F-K Lin, F-L Lin, H. L. Liu, G. C. Luo, L-W Majorana, E. Marchio, M. Michimura, Y. Mio, N. Miyakawa, O. Miyamoto, A. Miyazaki, Y. Miyo, K. Miyoki, S. Mori, Y. Morisaki, S. Moriwaki, Y. Nagano, K. Nagano, S. Nakamura, K. Nakano, H. Nakano, M. Nakashima, R. Nakayama, Y. Narikawa, T. Naticchioni, L. Negishi, R. Quynh, L. Nguyen Ni, W-T Nishizawa, A. Nozaki, S. Obuchi, Y. Ogaki, W. Oh, J. J. Oh, S. H. Ohashi, M. Ohishi, N. Ohkawa, M. Ohta, H. Okutani, Y. Okutomi, K. Oohara, K. Ooi, C. Oshino, S. Otabe, S. Pan, K-C Pang, H. Parisi, A. Park, J. Arellano, F. E. Pena Pinto, I. Sago, N. Saito, S. Saito, Y. Sakai, K. Sakai, Y. Sakuno, Y. Sato, S. Sato, T. Sawada, T. Sekiguchi, T. Sekiguchi, Y. Shao, L. Shibagaki, S. Shimizu, R. Shimoda, T. Shimode, K. Shinkai, H. Shishido, T. Shoda, A. Somiya, K. Son, E. J. Sotani, H. Sugimoto, R. Suresh, J. Suzuki, T. Suzuki, T. Tagoshi, H. Takahashi, H Gravitational Wave Science Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Department of Physics The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan Research Center for the Early Universe The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan Institute for Cosmic Ray Research KAGRA Observatory The University of Tokyo 5-1-5 Kashiwa-no-Ha Kashiwa City Chiba 277-8582 Japan Accelerator Laboratory High Energy Accelerator Research Organization (KEK) 1-1 Oho Tsukuba City Ibaraki 305-0801 Japan Earthquake Research Institute The University of Tokyo 1-1-1 Yayoi Bunkyo-ku Tokyo 113-0032 Japan Department of Mathematics and Physics Graduate School of Science and Technology Hirosaki University 3 Bunkyo-cho Hirosaki Aomori 036-8561 Japan Kamioka Branch National Astronomical Observatory of Japan 238 Higashi-Mozumi Kamioka-cho Hida City Gifu 506-1205 Japan The Graduate University for Advanced Studies (SOKENDAI) 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Korea Institute of Science and Technology Information 245 Daehak-ro Yuseong-gu Daejeon 34141 Republic of Korea National Institute for Mathematical Sciences 70 Yuseong-daero 1689 Beon-gil Yuseong-gu Daejeon 34047 Republic of Korea International College Osaka University 1-1 Machikaneyama-cho Toyonaka City Osaka 560-0043 Japan School of High Energy Accelerator Science The Graduate University for Advanced Studies (SOKENDAI) 1-1 Oho Tsukuba City Ibaraki 305-0801 Japan Department of Astronomy Beijing Normal University Xinjiekouwai Street 19 Haidian District Beijing 100875 China Department of Applied Physics Fukuoka University 8-19-1 Nanakuma Jonan Fukuoka City Fukuoka 814-0180 Japan Department of Physics Tamkang University No. 151 Yingzhuan Road Danshui Dist. New Taipei City 25137 Taiwan Department of Physics

KAGRA, the underground and cryogenic gravitational-wave detector, was operated for its solo observation from February 25 to March 10, 2020, and its first joint observation with the GEO 600 detector from April 7 to April 21, 2020 (O3GK). This study presents an overview of the input optics systems of the KAGRA detector, which consist of various optical systems, such as a laser source, its intensity and frequency stabilization systems, modulators, a Faraday isolator, mode-matching telescopes, and a high-power beam dump. These optics were successfully delivered to the KAGRA interferometer and operated stably during the observations. The laser frequency noise was observed to limit the detector sensitivity above a few kilohertz, whereas the laser intensity did not significantly limit the detector sensitivity.

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An arm length stabilization system for KAGRA and future gravitational-wave detectors

arXiv

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arXiv 2019年

作者： Akutsu, T. Ando, M. Arai, K. Arai, K. Arai, Y. Araki, S. Araya, A. Aritomi, N. Aso, Y. Bae, S. Bae, Y. Baiotti, L. Bajpai, R. Barton, M.A. Cannon, K. Capocasa, E. Chan, M. Chen, C. Chen, K. Chen, Y. Chu, H. Chu, Y.-K. Doi, K. Eguchi, S. Enomoto, Y. Flaminio, R. Fujii, Y. Fukunaga, M. Fukushima, M. Ge, G. Hagiwara, A. Haino, S. Hasegawa, K. Hayakawa, H. Hayama, K. Himemoto, Y. Hiranuma, Y. Hirata, N. Hirose, E. Hong, Z. Hsieh, B.H. Huang, G.-Z. Huang, P. Huang, Y. Ikenoue, B. Imam, S. Inayoshi, K. Inoue, Y. Ioka, K. Itoh, Y. Izumi, K. Jung, K. Jung, P. Kajita, T. Kamiizumi, M. Kanbara, S. Kanda, N. Kang, G. Kawaguchi, K. Kawai, N. Kawasaki, T. Kim, C. Kim, J.C. Kim, W.S. Kim, Y.-M. Kimura, N. Kita, N. Kitazawa, H. Kojima, Y. Kokeyama, K. Komori, K. Kong, A.K.H. Kotake, K. Kozakai, C. Kozu, R. Kumar, R. Kume, J. Kuo, C. Kuo, H.-S. Kuroyanagi, S. Kusayanagi, K. Kwak, K. Lee, H.K. Lee, H.W. Lee, R. Leonardi, M. Lin, L.C.-C. Lin, C.-Y. Lin, F.-L. Liu, G.C. Luo, L.-W. Marchio, M. Michimura, Y. Mio, N. Miyakawa, O. Miyamoto, A. Miyazaki, Y. Miyo, K. Miyoki, S. Morisaki, S. Moriwaki, Y. Musha, M. Nagano, K. Nagano, S. Nakamura, K. Nakano, H. Nakano, M. Nakashima, R. Narikawa, T. Negishi, R. Ni, W.-T. Nishizawa, A. Obuchi, Y. Ogaki, W. Oh, J.J. Oh, S.H. Ohashi, M. Ohishi, N. Ohkawa, M. Ohmae, N. Okutomi, K. Oohara, K. Ooi, C.P. Oshino, S. Pan, K. Pang, H. Park, J. Peña Arellano, F.E. Pinto, I. Sago, N. Saito, S. Saito, Y. Sakai, K. Sakai, Y. Sakuno, Y. Sato, S. Sato, T. Sawada, T. Sekiguchi, T. Sekiguchi, Y. Shibagaki, S. Shimizu, R. Shimoda, T. Shimode, K. Shinkai, H. Shishido, T. Shoda, A. Somiya, K. Son, E.J. Sotani, H. Sugimoto, R. Suzuki, T. Suzuki, T. Tagoshi, H. Takahashi, H. Takahashi, R. Takamori, A. Takano, S. Takeda, H. Takeda, M. Tanaka, H. Tanaka, K. Tanaka, K. Tanaka, T. Tanaka, T. Tanioka, S. San Martin, E.N. Tapia Mitaka City Tokyo181-8588 Japan Japan Department of Physics University of Tokyo Bunkyo-ku Tokyo113-0033 Japan University of Tokyo Bunkyo-ku Tokyo113-0033 Japan California Institute of Technology PasadenaCA91125 United States KAGRA Observatory University of Tokyo Kashiwa CityChiba277-8582 Japan Tsukuba CityIbaraki305-0801 Japan Earthquake Research Institute University of Tokyo Bunkyo-ku Tokyo113-0032 Japan Kamioka-cho Hida City Gifu506-1205 Japan Mitaka City Tokyo181-8588 Japan Yuseong-gu Daejeon34141 Korea Republic of National Institute for Mathematical Sciences Daejeon34047 Korea Republic of Department of Earth and Space Science Graduate School of Science Osaka University Toyonaka CityOsaka560-0043 Japan Tsukuba CityIbaraki305-0801 Japan Department of Applied Physics Fukuoka University Jonan Fukuoka CityFukuoka814-0180 Japan Department of Physics Tamkang University Danshui Dist. New Taipei City25137 Taiwan Department of Physics and Institute of Astronomy National Tsing Hua University Hsinchu30013 Taiwan Department of Physics Center for High Energy and High Field Physics National Central University Zhongli District Taoyuan City32001 Taiwan Institute of Physics Academia Sinica Nankang Taipei11529 Taiwan Department of Physics University of Toyama Toyama CityToyama930-8555 Japan Université Savoie Mont Blanc CNRS/IN2P3 AnnecyF-74941 France Department of Astronomy University of Tokyo Mitaka City Tokyo181-8588 Japan Chinese Academy of Sciences Xiaohongshan Wuhan430071 China Tsukuba CityIbaraki305-0801 Japan KAGRA Observatory University of Tokyo Kamioka-cho Hida City Gifu506-1205 Japan College of Industrial Technology Nihon University Narashino CityChiba275-8575 Japan Graduate School of Science and Technology Niigata University Nishi-ku Niigata City Niigata950-2181 Japan Department of Physics National Taiwan Normal University Taipei116 Taiwan University of Tokyo Kashiwa Ci

Modern ground-based gravitational wave (GW) detectors require a complex interferometer configuration with multiple coupled optical cavities. Since achieving the resonances of the arm cavities is the most challenging among the lock acquisition processes, the scheme called arm length stabilization (ALS) had been employed for lock acquisition of the arm cavities. We designed a new type of the ALS, which is compatible with the interferometers having long arms like the next generation GW detectors. The features of the new ALS are that the control configuration is simpler than those of previous ones and that it is not necessary to lay optical fibers for the ALS along the kilometer-long arms of the detector. Along with simulations of its noise performance, an experimental test of the new ALS was performed utilizing a single arm cavity of KAGRA. This paper presents the first results of the test where we demonstrated that lock acquisition of the arm cavity was achieved using the new ALS. We also demonstrated that the root mean square of residual noise was measured to be 8.2 Hz in units of frequency, which is smaller than the linewidth of the arm cavity and thus low enough to lock the full interferometer of KAGRA in a repeatable and reliable manner. Copyright © 2019, The Authors. All rights reserved.

关键词： Interferometers

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Overview of KAGRA: Detector design and construction history

arXiv

引用

arXiv 2020年

作者： Akutsu, T. Ando, M. Arai, K. Arai, Y. Araki, S. Araya, A. Aritomi, N. Aso, Y. Bae, S. Bae, Y. Baiotti, L. Bajpai, R. Barton, M.A. Cannon, K. Capocasa, E. Chan, M. Chen, C. Chen, K. Chen, Y. Chu, H. Chu, Y.-K. Eguchi, S. Enomoto, Y. Flaminio, R. Fujii, Y. Fukunaga, M. Fukushima, M. Ge, G. Hagiwara, A. Haino, S. Hasegawa, K. Hayakawa, H. Hayama, K. Himemoto, Y. Hiranuma, Y. Hirata, N. Hirose, E. Hong, Z. Hsieh, B.H. Huang, C.-Z. Huang, P. Huang, Y. Ikenoue, B. Imam, S. Inayoshi, K. Inoue, Y. Ioka, K. Itoh, Y. Izumi, K. Jung, K. Jung, P. Kajita, T. Kamiizumi, M. Kanda, N. Kang, G. Kawaguchi, K. Kawai, N. Kawasaki, T. Kim, C. Kim, J.C. Kim, W.S. Kim, Y.-M. Kimura, N. Kita, N. Kitazawa, H. Kojima, Y. Kokeyama, K. Komori, K. Kong, A.K.H. Kotake, K. Kozakai, C. Kozu, R. Kumar, R. Kume, J. Kuo, C. Kuo, H.-S. Kuroyanagi, S. Kusayanagi, K. Kwak, K. Lee, H.K. Lee, H.W. Lee, R. Leonardi, M. Lin, C. Lin, C.-Y. Lin, F.-L. Liu, G.C. Luo, L. Marchio, M. Michimura, Y. Mio, N. Miyakawa, O. Miyamoto, A. Miyazaki, Y. Miyo, K. Miyoki, S. Morisaki, S. Moriwaki, Y. Nagano, K. Nagano, S. Nakamura, K. Nakano, H. Nakano, M. Nakashima, R. Narikawa, T. Negishi, R. Ni, W.-T. Nishizawa, A. Obuchi, Y. Ogaki, W. Oh, J.J. Oh, S.H. Ohashi, M. Ohishi, N. Ohkawa, M. Okutomi, K. Oohara, K. Ooi, C.P. Oshino, S. Pan, K. Pang, H. Park, J. Peña Arellano, F.E. Pinto, I. Sago, N. Saito, S. Saito, Y. Sakai, K. Sakai, Y. Sakuno, Y. Sato, S. Sato, T. Sawada, T. Sekiguchi, T. Sekiguchi, Y. Shibagaki, S. Shimizu, R. Shimoda, T. Shimode, K. Shinkai, H. Shishido, T. Shoda, A. Somiya, K. Son, E.J. Sotani, H. Sugimoto, R. Suzuki, T. Suzuki, T. Tagoshi, H. Takahashi, H. Takahashi, R. Takamori, A. Takano, S. Takeda, H. Takeda, M. Tanaka, H. Tanaka, K. Tanaka, K. Tanaka, T. Tanaka, T. Tanioka, S. Tapia San Martin, E.N. Telada, S. Tomaru, T. Tomigami, Y. Tomura, T. Mitaka City Tokyo181-8588 Japan Japan Department of Physics University of Tokyo Bunkyo-ku Tokyo113-0033 Japan University of Tokyo Bunkyo-ku Tokyo113-0033 Japan KAGRA Observatory University of Tokyo Kashiwa City Chiba277-8582 Japan Tsukuba City Ibaraki305-0801 Japan Earthquake Research Institute University of Tokyo Bunkyo-ku Tokyo113-0032 Japan Kamioka-cho Hida City Gifu506-1205 Japan Mitaka City Tokyo181-8588 Japan Yuseong-gu Daejeon34141 Korea Republic of National Institute for Mathematical Sciences Daejeon34047 Korea Republic of Department of Earth and Space Science Graduate School of Science Osaka University Toyonaka City Osaka560-0043 Japan Tsukuba City Ibaraki305-0801 Japan Department of Applied Physics Fukuoka University Jonan Fukuoka City Fukuoka814-0180 Japan Department of Physics Tamkang University Danshui Dist. New Taipei City25137 Taiwan Department of Physics and Institute of Astronomy National Tsing Hua University Hsinchu30013 Taiwan Department of Physics Center for High Energy and High Field Physics National Central University Zhongli District Taoyuan City32001 Taiwan Institute of Physics Academia Sinica Nankang Taipei11529 Taiwan Université Savoie Mont Blanc CNRS/IN2P3 AnnecyF-74941 France Department of Astronomy University of Tokyo Mitaka City Tokyo181-8588 Japan Chinese Academy of Sciences Xiaohongshan Wuhan430071 China Tsukuba City Ibaraki305-0801 Japan KAGRA Observatory University of Tokyo Kamioka-cho Hida City Gifu506-1205 Japan College of Industrial Technology Nihon University Narashino City Chiba275-8575 Japan Graduate School of Science and Technology Niigata University Nishi-ku Niigata City Niigata950-2181 Japan Department of Physics National Taiwan Normal University sec. 4 Taipei116 Taiwan University of Tokyo Kashiwa City Chiba277-8582 Japan Kavli Institute for Astronomy and Astrophysics Peking University China Kyoto University Sakyou-ku Kyot

KAGRA is a newly built gravitational-wave telescope, a laser interferometer comprising arms with a length of 3 km, located in Kamioka, Gifu, Japan. KAGRA was constructed under the ground and it is operated using cryogenic mirrors that help in reducing the seismic and thermal noise. Both technologies are expected to provide directions for the future of gravitational-wave telescopes. In 2019, KAGRA finished all installations with the designed configuration, which we call the baseline KAGRA. In this occasion, we present an overview of the baseline KAGRA from various viewpoints in a series of of articles. In this article, we introduce the design configurations of KAGRA with its historical background. Copyright © 2020, The Authors. All rights reserved.

关键词： Laser interferometry

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Noise subtraction from KAGRA O3GK data using Independent Component Analysis

arXiv

引用

arXiv 2022年

作者： Abe, H. Akutsu, T. Ando, M. Araya, A. Aritomi, N. Asada, H. Aso, Y. Bae, S. Bae, Y. Bajpai, R. Cannon, K. Cao, Z. Capocasa, E. Chan, M. Chen, C. Chen, D. Chen, K. Chen, Y. Chiang, C.-Y. Chu, Y.-K. Eguchi, S. Eisenmann, M. Enomoto, Y. Flaminio, R. Fong, H.K. Fujii, Y. Fujikawa, Y. Fujimoto, Y. Fukunaga, I. Gao, D. Ge, G.-G. Ha, S. Hadiputrawan, I.P.W. Haino, S. Han, W.-B. Hasegawa, K. Hattori, K. Hayakawa, H. Hayama, K. Himemoto, Y. Hirata, N. Hirose, C. Ho, T.-C. Hsieh, B.-H. Hsieh, H.-F. Hsiung, C. Huang, H.-Y. Huang, P. Huang, Y.-C. Huang, Y.-J. Hui, D.C.Y. Ide, S. Inayoshi, K. Inoue, Y. Ito, K. Itoh, Y. Jeon, C. Jin, H.-B. Jung, K. Jung, P. Kaihotsu, K. Kajita, T. Kakizaki, M. Kamiizumi, M. Kanda, N. Kato, T. Kawaguchi, K. Kim, C. Kim, J. Kim, J.C. Kim, Y.-M. Kimura, N. Kiyota, T. Kobayashi, Y. Kohri, K. Kokeyama, K. Kong, A.K.H. Koyama, N. Kozakai, C. Kume, J. Kuromiya, Y. Kuroyanagi, S. Kwak, K. Lee, E. Lee, H.W. Lee, R. Leonardi, M. Li, K.L. Li, P. Lin, L.C.-C. Lin, C.-Y. Lin, E.T. Lin, F.-K. Lin, F.-L. Lin, H.L. Liu, G.C. Luo, L.-W. Ma'arif, M. Majorana, E. Michimura, Y. Mio, N. Miyakawa, O. Miyo, K. Miyoki, S. Mori, Y. Morisaki, S. Morisue, N. Moriwaki, Y. Nagano, K. Nakamura, K. Nakano, H. Nakano, M. Nakayama, Y. Narikawa, T. Naticchioni, L. Nguyen Quynh, L. Ni, W.-T. Nishimoto, T. Nishizawa, A. Nozaki, S. Obayashi, Y. Ogaki, W. Oh, J.J. Oh, K. Ohashi, M. Ohashi, T. Ohkawa, M. Ohta, H. Okutani, Y. Oohara, K. Oshino, S. Otabe, S. Pan, K.-C. Parisi, A. Park, J. Peña Arellano, F.E. Saha, S. Saito, Y. Sakai, K. Sawada, T. Sekiguchi, Y. Shao, L. Shikano, Y. Shimizu, H. Shimode, K. Shinkai, H. Shishido, T. Shoda, A. Somiya, K. Song, I. Sugimoto, R. Suresh, J. Suzuki, T. Suzuki, T. Suzuki, T. Tagoshi, H. Takahashi, H. Takahashi, R. Takano, S. Takeda, H. Takeda, M. Tanaka, K. Tanaka, T. Tanaka, T. Tanioka, S. Taruya, A. Graduate School of Science Tokyo Institute of Technology Meguro-ku Tokyo152-8551 Japan Mitaka City Tokyo181-8588 Japan Mitaka City Tokyo181-8588 Japan Department of Physics The University of Tokyo Bunkyo-ku Tokyo113-0033 Japan The University of Tokyo Bunkyo-ku Tokyo113-0033 Japan Earthquake Research Institute The University of Tokyo Bunkyo-ku Tokyo113-0032 Japan Department of Mathematics and Physics Gravitational Wave Science Project Hirosaki University Aomori Hirosaki City036-8561 Japan Kamioka-cho Hida City Gifu506-1205 Japan Mitaka City Tokyo181-8588 Japan Yuseong-gu Daejeon34141 Korea Republic of National Institute for Mathematical Sciences Yuseong-gu Daejeon34047 Korea Republic of Ibaraki Tsukuba City305-0801 Japan Department of Astronomy Beijing Normal University Beijing100875 China Department of Applied Physics Fukuoka University Jonan Fukuoka Fukuoka City814-0180 Japan Department of Physics Tamkang University Danshui Dist. New Taipei City25137 Taiwan Department of Physics Institute of Astronomy National Tsing Hua University Hsinchu30013 Taiwan Department of Physics Center for High Energy and High Field Physics National Central University Zhongli District Taoyuan City32001 Taiwan Department of Physics National Tsing Hua University Hsinchu30013 Taiwan Institute of Physics Academia Sinica Nankang Taipei11529 Taiwan Université Savoie Mont Blanc CNRS IN2P3 AnnecyF-74941 France Department of Astronomy The University of Tokyo Mitaka City Tokyo181-8588 Japan Faculty of Engineering Niigata University Nishi-ku Niigata Niigata City950-2181 Japan Department of Physics Graduate School of Science Osaka City University Sumiyoshi-ku Osaka City Osaka558-8585 Japan Chinese Academy of Sciences Xiao Hong Shan Wuhan430071 China Ulju-gun Ulsan44919 Korea Republic of Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai200030 China KAGRA Observatory The University of Tok

In April 2020, KAGRA conducted its first science observation in combination with the GEO 600 detector (O3GK) for two weeks. According to the noise budget estimation, suspension control noise in the low frequency band and acoustic noise in the middle frequency band are identified as the dominant contribution. In this study, we show that such noise can be reduced in offline data analysis by utilizing a method called Independent Component Analysis (ICA). Here the ICA model is extended from the one studied in iKAGRA data analysis by incorporating frequency dependence while linearity and stationarity of the couplings are still assumed. By using optimal witness sensors, those two dominant contributions are mitigated in the real observational data. We also analyze the stability of the transfer functions for whole two weeks data in order to investigate how the current subtraction method can be practically used in gravitational wave search. Copyright © 2022, The Authors. All rights reserved.

关键词： Data handling

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Benchmarking the CoW with the TopCoW Challenge: Topology-Aware Anatomical Segmentation of the Circle of Willis for CTA and MRA

arXiv

引用

arXiv 2023年

作者： Yang, Kaiyuan Musio, Fabio Ma, Yihui Juchler, Norman Paetzold, Johannes C. Al-Maskari, Rami Höher, Luciano Li, Hongwei Bran Hamamci, Ibrahim Ethem Sekuboyina, Anjany Shit, Suprosanna Huang, Houjing Prabhakar, Chinmay de la Rosa, Ezequiel Waldmannstetter, Diana Kofler, Florian Navarro, Fernando Menten, Martin Ezhov, Ivan Rueckert, Daniel Vos, Iris Ruigrok, Ynte Velthuis, Birgitta Kuijf, Hugo Hämmerli, Julien Wurster, Catherine Bijlenga, Philippe Westphal, Laura Bisschop, Jeroen Colombo, Elisa Baazaoui, Hakim Makmur, Andrew Hallinan, James Wiestler, Bene Kirschke, Jan S. Wiest, Roland Montagnon, Emmanuel Letourneau-Guillon, Laurent Galdran, Adrian Galati, Francesco Falcetta, Daniele Zuluaga, Maria A. Lin, Chaolong Zhao, Haoran Zhang, Zehan Ra, Sinyoung Hwang, Jongyun Park, Hyunjin Chen, Junqiang Wodzinski, Marek Müller, Henning Shi, Pengcheng Liu, Wei Ma, Ting Yalçin, Cansu Hamadache, Rachika E. Salvi, Joaquim Llado, Xavier Estrada, Uma Maria Lal-Trehan Abramova, Valeriia Giancardo, Luca Oliver, Arnau Liu, Jialu Huang, Haibin Cui, Yue Lin, Zehang Liu, Yusheng Zhu, Shunzhi Patel, Tatsat R. Tutino, Vincent M. Orouskhani, Maysam Wang, Huayu Mossa-Basha, Mahmud Zhu, Chengcheng Rokuss, Maximilian R. Kirchhoff, Yannick Disch, Nico Holzschuh, Julius Isensee, Fabian Maier-Hein, Klaus Sato, Yuki Hirsch, Sven Wegener, Susanne Menze, Bjoern Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Center for Computational Health Zurich University of Applied Sciences Zurich Switzerland Department of Neuroradiology University Hospital of Zurich Zurich Switzerland Department of Neurosurgery Zhongnan Hospital of Wuhan University Wuhan China Department of Computing Imperial College London London United Kingdom Helmholtz Center Munich Germany Athinoula A. Martinos Center for Biomedical Imaging Harvard Medical School Boston United States School of Medicine Technical University of Munich Munich Germany Department of Informatics Technical University of Munich Munich Germany Helmholtz AI Helmholtz Munich Munich Germany Image Sciences Institute UMC Utrecht Utrecht Netherlands Department of Neurology UMC Utrecht Utrecht Netherlands Department of Radiology UMC Utrecht Utrecht Netherlands Department of Clinical Neurosciences Division of Neurosurgery Geneva University Hospitals Geneva Switzerland Department of Neurology University Hospital of Zurich Zurich Switzerland Department of Physiology University of Toronto Toronto Canada Department of Neurosurgery University Hospital of Zurich Zurich Switzerland Department of Diagnostic Imaging National University Hospital Singapore Department of Diagnostic and Interventional Neuroradiology University Hospital Berne University of Berne Berne Switzerland Montreal Canada Universitat Pompeu Fabra Barcelona Spain EURECOM Biot France Institute of Medical Technology Peking University Health Science Center Beijing China Hangzhou Genlight Medtech Co. Ltd. Hangzhou China Department of Artificial Intelligence Sungkyunkwan University Seoul Korea Republic of Department of Electrical and Computer Engineering Sungkyunkwan University Seoul Korea Republic of Shanghai MediWorks Precision Instruments Co. Ltd. Shanghai China Institute of Informatics HES-SO Valais-Wallis Switzerland Department of Measurement and Electronics AGH University

The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to affect the risk, severity, and clinical outcome of serious neuro-vascular diseases. However, characterizing the highly variable CoW anatomy is still a manual and time-consuming expert task. The CoW is usually imaged by two angiographic imaging modalities, magnetic resonance angiography (MRA) and computed tomography angiography (CTA), but there exist limited public datasets with annotations on CoW anatomy, especially for CTA. Therefore we organized the TopCoW Challenge in 2023 with the release of an annotated CoW dataset. The TopCoW dataset was the first public dataset with voxel-level annotations for thirteen possible CoW vessel components, enabled by virtual-reality (VR) technology. It was also the first large dataset with paired MRA and CTA from the same patients. TopCoW challenge formalized the CoW characterization problem as a multiclass anatomical segmentation task with an emphasis on topological metrics. We invited submissions worldwide for the CoW segmentation task, which attracted over 140 registered participants from four continents. The top performing teams managed to segment many CoW components to Dice scores around 90%, but with lower scores for communicating arteries and rare variants. There were also topological mistakes for predictions with high Dice scores. Additional topological analysis revealed further areas for improvement in detecting certain CoW components and matching CoW variant topology accurately. TopCoW represented a first attempt at benchmarking the CoW anatomical segmentation task for MRA and CTA, both morphologically and topologically. © 2023, CC BY-NC-ND.

关键词： Large datasets

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