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Genomic basis for RNA alterations in cancer (vol 578, pg 129, 2020)

NATURE 2023年第7948期614卷 E37-E37页

作者： Calabrese, Claudia Davidson, Natalie R. Demircioglu, Deniz Fonseca, Nuno A. He, Yao Lehmann, Kjong-Van Liu, Fenglin Shiraishi, Yuichi Soulette, Cameron M. Urban, Lara Greger, Liliana Li, Siliang Liu, Dongbing Perry, Marc D. Xiang, Qian Zhang, Fan Zhang, Junjun Bailey, Peter Erkek, Serap Hoadley, Katherine A. Hou, Yong Huska, Matthew R. Kilpinen, Helena Korbel, Jan O. Marin, Maximillian G. Markowski, Julia Nandi, Tannistha Pan-Hammarstrom, Qiang Pedamallu, Chandra Sekhar Siebert, Reiner Stark, Stefan G. Su, Hong Tan, Patrick Waszak, Sebastian M. Yung, Christina Zhu, Shida Awadalla, Philip Creighton, Chad J. Meyerson, Matthew Ouellette, B. F. Francis Wu, Kui Yang, Huanming Brazma, Alvis Brooks, Angela N. Goke, Jonathan Ratsch, Gunnar Schwarz, Roland F. Stegle, Oliver Zhang, Zemin European Molecular Biology Laboratory European Bioinformatics Institute Hinxton UK European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany CIBIO/InBIO - Research Center in Biodiversity and Genetic Resources Universidade do Porto Vairão Portugal Berlin Institute for Medical Systems Biology Max Delbruck Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) partner site Berlin Germany German Cancer Research Center (DKFZ) Heidelberg Germany Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) Partner site Berlin Berlin Germany European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Division of Computational Genomics and Systems Genetics German Cancer Research Center (DKFZ) Heidelberg Germany ETH Zurich Zurich Switzerland Memorial Sloan Kettering Cancer Center New York NY USA Weill Cornell Medical College New York NY USA SIB Swiss Institute of Bioinformatics Lausanne Switzerland University Hospital Zurich Zurich Switzerland Computational Biology Center Memorial Sloan Kettering Cancer Center New York NY USA Department of Biology ETH Zurich Zürich Switzerland Department of Computer Science ETH Zurich Zurich Switzerland Korea University Seoul South Korea Computational and Systems Biology Program Memorial Sloan Kettering Cancer Center New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine New York NY USA National University of Singapore Singapore Singapore Genome Institute of Singapore Singapore Singapore Computational and Systems Biology Genome Institute of Singap

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Searches for neutrino counterparts of gravitational waves from the LIGO/Virgo third observing run with KM3NeT

arXiv

引用

arXiv 2023年

作者： Aiello, S. Albert, A. Garre, S. Alves Aly, Z. Ambrosone, A. Ameli, F. Andre, M. Androutsou, E. Anguita, M. Aphecetche, L. Ardid, M. Ardid, S. Atmani, H. Aublin, J. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. du Pree, S. Basegmez Becherini, Y. Bendahman, M. Benfenati, F. Benhassi, M. Benoit, D.M. Berbee, E. Bertin, V. Biagi, S. Boettcher, M. Bonanno, D. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Campion, S. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chadolias, M. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Cocimano, R. Coelho, J.A.B. Coleiro, A. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. Dallier, R. Darras, Y. De Benedittis, A. De Martino, B. De Wasseige, G. Decoene, V. Del Burgo, R. Del Rosso, I. Di Cerbo, U.M. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diaz, C. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Dörr, M. Drakopoulou, E. Drouhin, D. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. El Bojaddaini, I. El Hedri, S. Enzenhöfer, A. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gabriel, J. Gagliardini, S. Gal, T. Méndez, J. García Soto, A. Garcia Oliver, C. Gatius Geißelbrecht, N. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goswami, P. Goupilliere, D. Gozzini, S.R. Gracia, R. Graf, K. Guidi, C. Guillon, B. Gutiérrez, M. van Haren, H. Heijboer, A. Hekalo, A. Hennig, L. Hernández-Rey, J.J. Ibnsalih, W. Idrissi Illuminati, G. de Jong, M. de Jong, P. Jung, B.J. Kalaczyn´ski, P. Kalekin, O. Katz, U.F. Khatun, A. Kistauri, G. Kopper, C. Kouchner, A. Kueviakoe, V. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. Lamoureux, M. Larosa, G. Lastoria, C. Lazo, A. Le Stum, S. Lehaut, G. Leonora, E. INFN Sezione di Catania Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France c/Catedrático José Beltrán 2 Paterna Valencia46980 Spain Aix Marseille Univ CNRS IN2P3 CPPM Marseille France INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d’Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain NCSR Demokritos Institute of Nuclear and Particle Physics Ag. Paraskevi Attikis Athens15310 Greece University of Granada Dept. of Computer Architecture and Technology/CITIC Granada18071 Spain Subatech IMT Atlantique IN2P3-CNRS Nantes Université 4 rue Alfred Kastler - La Chantrerie BP Nantes20722 44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/ Paranimf 1 Gandia46730 Spain University Mohammed V in Rabat Faculty of Sciences 4 av. Ibn Battouta B.P. 1014 RabatR.P. 10000 Morocco Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 boulevard Maréchal Juin Caen14050 France Czech Technical University in Prague Institute of Experimental and Applied Physics Husova 240/5 Prague110 00 Czech Republic Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia Nikhef National Institute for Subatomic Physics PO Box 41882 Amsterdam1009 DB Netherlands INFN Sezione di Bologna v.le C. Berti-Pichat 6/2 Bologna40127 Italy Università di Bologna Dipartimento di Fisica e Astronomia v.le C. Berti-Pichat

The KM3NeT neutrino telescope is currently being deployed at two different sites in the Mediterranean Sea. First searches for astrophysical neutrinos have been performed using data taken with the partial detector configuration already in operation. The paper presents the results of two independent searches for neutrinos from compact binary mergers detected during the third observing run of the LIGO and Virgo gravitational wave interferometers. The first search looks for a global increase in the detector counting rates that could be associated with inverse beta decay events generated by MeV-scale electron anti-neutrinos. The second one focuses on upgoing track-like events mainly induced by muon (anti-)neutrinos in the GeV–TeV energy range. Both searches yield no significant excess for the sources in the gravitational wave catalogs. For each source, upper limits on the neutrino flux and on the total energy emitted in neutrinos in the respective energy ranges have been set. Stacking analyses of binary black hole mergers and neutron star-black hole mergers have also been performed to constrain the characteristic neutrino emission from these categories. Copyright © 2023, The Authors. All rights reserved.

关键词： Gravity waves

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The Power Board of the KM3NeT Digital Optical Module: design, upgrade, and production

arXiv

引用

arXiv 2023年

作者： Aiello, S. Albert, A. Garre, S. Alves Aly, Z. Ambrosone, A. Ameli, F. Andre, M. Androutsou, E. Anguita, M. Aphecetche, L. Ardid, M. Ardid, S. Atmani, H. Aublin, J. Badaracco, F. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. du Pree, S. Basegmez Becherini, Y. Bendahman, M. Benfenati, F. Benhassi, M. Benoit, D.M. Berbee, E. Bertin, V. van Beveren, V. Biagi, S. Boettcher, M. Bonanno, D. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Campion, S. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chadolias, M. Champion, C. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Cocimano, R. Coelho, J.A.B. Coleiro, A. Colonges, S. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. Dallier, R. Darras, Y. De Benedittis, A. De Martino, B. Decoene, V. Del Burgo, R. Del Rosso, I. Di Cerbo, U.M. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diaz, C. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Dörr, M. Drakopoulou, E. Drouhin, D. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. Bojaddaini, I. El Hedri, S. El Enzenhöfer, A. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gabella, O. Gabriel, J. Gagliardini, S. Gal, T. Méndez, J. García Soto, A. Garcia Oliver, C. Gatius Geißelbrecht, N. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goswami, P. Goupilliere, D. Gozzini, S.R. Gracia, R. Graf, K. Guidi, C. Guillon, B. Gutiérrez, M. van Haren, H. Heijboer, A. Hekalo, A. Hennig, L. Hernández-Rey, J.J. Ibnsalih, W. Idrissi Illuminati, G. Jansweijer, P. de Jong, M. de Jong, P. Jung, B.J. Kalaczyn´ski, P. Kalekin, O. Katz, U.F. Khatun, A. Kistauri, G. Kopper, C. Kouchner, A. Kueviakoe, V. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. Larosa, G. INFN Sezione di Catania Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France c/Catedrático José Beltrán 2 Paterna Valencia46980 Spain Aix Marseille Univ CNRS IN2P3 CPPM Marseille France INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d’Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain NCSR Demokritos Institute of Nuclear and Particle Physics Ag. Paraskevi Attikis Athens15310 Greece University of Granada Dept. of Computer Architecture and Technology/CITIC Granada18071 Spain Subatech IMT Atlantique IN2P3-CNRS Nantes Université 4 rue Alfred Kastler - La Chantrerie BP Nantes20722 44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/ Paranimf 1 Gandia46730 Spain University Mohammed V in Rabat Faculty of Sciences 4 av. Ibn Battouta B.P. 1014 RabatR.P. 10000 Morocco Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France INFN Sezione di Genova Via Dodecaneso 33 Genova16146 Italy LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 boulevard Maréchal Juin Caen14050 France Czech Technical University in Prague Institute of Experimental and Applied Physics Husova 240/5 Prague110 00 Czech Republic Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia Nikhef National Institute for Subatomic Physics PO Box 41882 Amsterdam1009 DB Netherlands INFN Sezione di Bologna v.le C. Berti-Pichat 6/2 Bologna40127 Italy Università di Bolo

The KM3NeT Collaboration is building an underwater neutrino observatory at the bottom of the Mediterranean Sea consisting of two neutrino telescopes, both composed of a three-dimensional array of light detectors, known as digital optical modules. Each digital optical module contains a set of 31 three-inch photomultiplier tubes distributed over the surface of a 0.44 m diameter pressure-resistant glass sphere. The module includes also calibration instruments and electronics for power, readout and data acquisition. The power board was developed to supply power to all the elements of the digital optical module. The design of the power board began in 2013, and several prototypes were produced and tested. After an exhaustive validation process in various laboratories within the KM3NeT Collaboration, a mass production batch began, resulting in the construction of over 1,200 power boards so far. These boards were integrated in the digital optical modules that have already been produced and deployed, 828 until October 2023. In 2017, an upgrade of the power board, to increase reliability and efficiency, was initiated. After the validation of a pre-production series, a production batch of 800 upgraded boards is currently underway. This paper describes the design, architecture, upgrade, validation, and production of the power board, including the reliability studies and tests conducted to ensure the safe operation at the bottom of the Mediterranean Sea throughout the observatory’s lifespan. © 2023, CC BY-NC-SA.

关键词： Photomultipliers

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Contributions of KM3NeT to ICRC2023

arXiv

引用

arXiv 2023年

作者： Aiello, S. Albert, A. Alves Garre, S. Aly, Z. Ambrosone, A. Ameli, F. Andre, M. Androutsou, E. Anguita, M. Aphecetche, L. Ardid, M. Ardid, S. Atmani, H. Aublin, J. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. Basegmez du Pree, S. Becherini, Y. Bendahman, M. Benfenati, F. Benhassi, M. Benoit, D.M. Berbee, E. Bertin, V. Biagi, S. Boettcher, M. Bonanno, D. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Campion, S. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chadolias, M. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Cocimano, R. Coelho, J.A.B. Coleiro, A. Coniglione, R. Coyle, P. Creusot, A. Cruz, A. Cuttone, G. Dallier, R. Darras, Y. De Benedittis, A. De Martino, B. De Wasseige, G. Decoene, V. Del Burgo, R. Di Cerbo, U.M. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diaz, C. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Dörr, M. Drakopoulou, E. Drouhin, D. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. El Bojaddaini, I. El Hedri, S. Enzenhöfer, A. de Favereau, J. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gabriel, J. Gagliardini, S. Gal, T. García Méndez, J. Garcia Soto, A. Gatius Oliver, C. Geißelbrecht, N. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goupilliere, D. Gozzini, S.R. Gracia, R. Graf, K. Guidi, C. Guillon, B. Gutiérrez, M. van Haren, H. Heijboer, A. Hekalo, A. Hennig, L. Hernández-Rey, J.J. Huang, F. Idrissi Ibnsalih, W. Illuminati, G. James, C.W. de Jong, M. de Jong, P. Jung, B.J. Kalaczyński, P. Kalekin, O. Katz, U.F. Khan Chowdhury, N.R. Khatun, A. Kistauri, G. Kopper, C. Kouchner, A. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. Lamoureux, M. Larosa, G. Lastoria, C. Lazo, A. Le Guirriec, E. Le Stum, S. INFN Sezione di Catania Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France c/Catedrático José Beltrán 2 Valencia Paterna46980 Spain Aix Marseille Univ CNRS IN2P3 CPPM Marseille France INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d'Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain NCSR Demokritos Institute of Nuclear and Particle Physics Ag. Paraskevi Attikis Athens15310 Greece University of Granada Dept. of Computer Architecture and Technology CITIC Granada18071 Spain Subatech IMT Atlantique IN2P3-CNRS Université de Nantes 4 rue Alfred Kastler - La Chantrerie BP 20722 Nantes44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/Paranimf 1 Gandia46730 Spain University Mohammed V in Rabat Faculty of Sciences 4 av. Ibn Battouta B.P. 1014 RabatR.P. 10000 Morocco Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 boulevard Maréchal Juin Caen14050 France Czech Technical University in Prague Institute of Experimental and Applied Physics Husova 240/5 Prague110 00 Czech Republic Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia Nikhef National Institute for Subatomic Physics PO Box 41882 Amsterdam1009 DB Netherlands INFN Sezione di Bologna v.le C. Berti-Pichat 6/2 Bologna40127 Italy Università di Bologna Dipartimento di Fisica e Astronomia v.le C. Berti-Picha

This document collects the contributions of the KM3NeT collaboration to the ICRC2023 conference, held from July 26 to August 3, 2023, in Nagoya, Japan. KM3NeT submitted 38 contributions to ICRC2023, on neutrino- and multimessenger astronomy, neutrino oscillation physics, cosmic ray physics, searches for dark matter and exotics, calibration, technical detector descriptions, and art. Proceedings are published in Proceedings of Science. © 2023, CC BY-NC-ND.

关键词： Cosmology

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SPT clusters with DES and HST weak lensing. I. Cluster lensing and Bayesian population modeling of multiwavelength cluster datasets

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Physical Review D 2024年第8期110卷 083509页

作者： S. Bocquet S. Grandis L. E. Bleem M. Klein J. J. Mohr M. Aguena A. Alarcon S. Allam S. W. Allen O. Alves A. Amon B. Ansarinejad D. Bacon M. Bayliss K. Bechtol M. R. Becker B. A. Benson G. M. Bernstein M. Brodwin D. Brooks A. Campos R. E. A. Canning J. E. Carlstrom A. Carnero Rosell M. Carrasco Kind J. Carretero R. Cawthon C. Chang R. Chen A. Choi J. Cordero M. Costanzi L. N. da Costa M. E. S. Pereira C. Davis J. DeRose S. Desai T. de Haan J. De Vicente H. T. Diehl S. Dodelson P. Doel C. Doux A. Drlica-Wagner K. Eckert J. Elvin-Poole S. Everett I. Ferrero A. Ferté A. M. Flores J. Frieman J. García-Bellido M. Gatti G. Giannini M. D. Gladders D. Gruen R. A. Gruendl I. Harrison W. G. Hartley K. Herner S. R. Hinton D. L. Hollowood W. L. Holzapfel K. Honscheid N. Huang E. M. Huff D. J. James M. Jarvis G. Khullar K. Kim R. Kraft K. Kuehn N. Kuropatkin F. Kéruzoré S. Lee P.-F. Leget N. MacCrann G. Mahler A. Mantz J. L. Marshall J. McCullough M. McDonald J. Mena-Fernández R. Miquel J. Myles A. Navarro-Alsina R. L. C. Ogando A. Palmese S. Pandey A. Pieres A. A. Plazas Malagón J. Prat M. Raveri C. L. Reichardt J. Roberson R. P. Rollins A. K. Romer C. Romero A. Roodman A. J. Ross E. S. Rykoff L. Salvati C. Sánchez E. Sanchez D. Sanchez Cid A. Saro T. Schrabback M. Schubnell L. F. Secco I. Sevilla-Noarbe K. Sharon E. Sheldon T. Shin M. Smith T. Somboonpanyakul B. Stalder A. A. Stark V. Strazzullo E. Suchyta M. E. C. Swanson G. Tarle C. To M. A. Troxel I. Tutusaus T. N. Varga A. von der Linden N. Weaverdyck J. Weller P. Wiseman B. Yanny B. Yin M. Young Y. Zhang J. Zuntz University Observatory Faculty of Physics Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstr. 25/8 6020 Innsbruck Austria Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Kavli Institute for Cosmological Physics University of Chicago Chicago Illinois 60637 USA Max Planck Institute for Extraterrestrial Physics Gießenbachstr. 1 85748 Garching Germany Laboratório Interinstitucional de e-Astronomia - LIneA Rua Gal. José Cristino 77 Rio de Janeiro RJ-20921-400 Brazil Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall Stanford California 94305 USA Department of Physics Stanford University 382 Via Pueblo Mall Stanford California 94305 USA SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo Park California 94025 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom School of Physics University of Melbourne Parkville Victoria 3010 Australia Institute of Cosmology and Gravitation University of Portsmouth Portsmouth PO1 3FX United Kingdom Department of Physics University of Cincinnati Cincinnati Ohio 45221 USA Physics Department 2320 Chamberlin Hall University of Wisconsin-Madison 1150 University Avenue Madison Wisconsin 53706-1390 USA Department of Astronomy and Astrophysics University of Chicago Chicago Illinois 60637 USA Fermi National Accelerator Laboratory Batavia Illinois 60510-0500 USA Department of Physics and Astronomy University of Pennsylvania Philadelphia Pennsylvania 19104 USA Department of Physics and Astronomy University of Missouri 5110 Rockhill Road Kansas City Missouri 64110 USA Department of Physics and Astronomy University Coll

We present a Bayesian population modeling method to analyze the abundance of galaxy clusters identified by the South Pole Telescope (SPT) with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). We discuss and validate the modeling choices with a particular focus on a robust, weak-lensing-based mass calibration using DES data. For the DES Year 3 data, we report a systematic uncertainty in weak-lensing mass calibration that increases from 1% at z=0.25 to 10% at z=0.95, to which we add 2% in quadrature to account for uncertainties in the impact of baryonic effects. We implement an analysis pipeline that joins the cluster abundance likelihood with a multiobservable likelihood for the Sunyaev-Zel’dovich effect, optical richness, and weak-lensing measurements for each individual cluster. We validate that our analysis pipeline can recover unbiased cosmological constraints by analyzing mocks that closely resemble the cluster sample extracted from the SPT-SZ, SPTpol ECS, and SPTpol 500d surveys and the DES Year 3 and HST-39 weak-lensing datasets. This work represents a crucial prerequisite for the subsequent cosmological analysis of the real dataset.

关键词： Cosmological parameters Gravitational lenses Large scale structure of the Universe

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Performance update of an event-type based analysis for the Cherenkov Telescope Array

arXiv

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arXiv 2023年

作者： Bernete, J. Sinha, A. Abe, K. Abe, S. Acharyya, A. Adam, R. Aguasca-Cabot, A. Agudo, I. Alfaro, J. Alvarez-Crespo, N. Alves Batista, R. Amans, J.-P. Amato, E. Ambrosino, F. Angüner, E.O. Antonelli, L.A. Aramo, C. Arcaro, C. Arrabito, L. Asano, K. Aschersleben, J. Ashkar, H. Augusto Stuani, L. Baack, D. Backes, M. Balazs, C. Balbo, M. Baquero Larriva, A. Barbosa Martins, V. Barres de Almeida, U. Barrio, J.A. Bastieri, D. Batista, P.I. Batkovic, I. Batzofin, R. Baxter, J. Beck, G. Becker Tjus, J. Beiske, L. Belardinelli, D. Benbow, W. Bernardini, E. Bernete Medrano, J. Bernlöhr, K. Berti, A. Beshley, V. Bhattacharjee, P. Bhattacharyya, S. Bi, B. Biederbeck, N. Biland, A. Bissaldi, E. Blanch, O. Blazek, J. Boisson, C. Bolmont, J. Bonnoli, G. Bordas, P. Bosnjak, Z. Bradascio, F. Braiding, C. Bronzini, E. Brose, R. Brown, A.M. Brun, F. Brunelli, G. Bulgarelli, A. Burelli, I. Burmistrov, L. Burton, M. Bylund, T. Calisse, P.G. Campoy-Ordaz, A. Cantlay, B.K. Capalbi, M. Caproni, A. Capuzzo-Dolcetta, R. Carlile, C. Caroff, S. Carosi, A. Carosi, R. Carrasco, M.-S. Cascone, E. Cassol, F. Castrejon, N. Catalani, F. Cerasole, D. Cerruti, M. Chaty, S. Chen, A.W. Chernyakova, M. Chiavassa, A. Chudoba, J. Coimbra Araujo, C.H. Conforti, V. Conte, F. Contreras, J.L. Cossou, C. Costa, A. Costantini, H. Cristofari, P. Cuevas, O. Curtis-Ginsberg, Z. D'Amico, G. D'Ammando, F. Dadina, M. Dalchenko, M. David, L. Davids, I.D. Dazzi, F. De Angelis, A. de Bony de Lavergne, M. De Caprio, V. De Cesare, G. de Gouveia Dal Pino, E.M. De Lotto, B. De Lucia, M. de Menezes, R. de Naurois, M. de Ona Wilhelmi, E. De Simone, N. de Souza, V. del Peral, L. del Valle, M.V. Delagnes, E. Delgado Giler, A.G. Delgado, C. Dell'aiera, M. Della Ceca, R. Della Valle, M. della Volpe, D. Depaoli, D. Dettlaff, A. Di Girolamo, T. Di Piano, A. Di Pierro, F. Di Tria, R. Di Venere, L. Díaz-Bahamondes, C. Dib, C. Diebold, S. Dima, R. Dinesh, A. Djannati-Ataï, A. Djuvsland, J. Domínguez, A. Dominik, R.M. Donini, A. Dorner, D. Department of Physics Tokai University 4-1-1 Kita-Kaname Kanagawa Hiratsuka259-1292 Japan Institute for Cosmic Ray Research University of Tokyo 5-1-5 Kashiwa-no-ha Chiba Kashiwa277-8582 Japan University of Alabama Tuscaloosa Department of Physics and Astronomy Gallalee Hall Box 870324 TuscaloosaAL35487-0324 United States Université Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange France Laboratoire Leprince-Ringuet CNRS IN2P3 École Polytechnique Institut Polytechnique de Paris Palaiseau91120 France Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Martí i Franquès 1 Barcelona08028 Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n Granada18008 Spain Pontificia Universidad Católica de Chile Av. Libertador Bernardo O'Higgins 340 Santiago Chile IPARCOS-UCM Instituto de Física de Partículas y del Cosmos EMFTEL Department Universidad Complutense de Madrid MadridE-28040 Spain Instituto de Física Teórica UAM CSIC Departamento de Física Teórica Universidad Autónoma de Madrid Campus de Cantoblanco UAM c/Nicolás Cabrera 13-15 Madrid28049 Spain LUTH GEPI LERMA Observatoire de Paris Université PSL Université Paris Cité CNRS 5 place Jules Janssen Meudon92190 France INAF - Osservatorio Astrofisico di Arcetri Largo E. Fermi 5 Firenze50125 Italy INAF - Osservatorio Astronomico di Roma Via di Frascati 33 Monteporzio Catone00040 Italy TÜBİTAK Research Institute for Fundamental Sciences Kocaeli Gebze41470 Turkey INFN Sezione di Napoli Via Cintia ed. G Napoli80126 Italy INFN Sezione di Padova Via Marzolo 8 Padova35131 Italy Laboratoire Univers et Particules de Montpellier Université de Montpellier CNRS IN2P3 CC 72 Place Eugène Bataillon MontpellierF-34095 Cedex 5 France Kapteyn Astronomical Institute University of Groningen Landleven 12 Groningen9747 AD Netherlands Instituto de Física de São Carlos Universidade de São Pa

The Cherenkov Telescope Array (CTA) will be the next-generation observatory in the field of very-high-energy (20 GeV to 300 TeV) gamma-ray astroparticle physics. The traditional approach to data analysis in this field is to apply quality cuts, optimized using Monte Carlo simulations, on the data acquired to maximize sensitivity. Subsequent steps of the analysis typically use the surviving events to calculate one set of instrument response functions (IRFs) to physically interpret the results. However, an alternative approach is the use of event types, as implemented in experiments such as the Fermi-LAT. This approach divides events into sub-samples based on their reconstruction quality, and a set of IRFs is calculated for each sub-sample. The sub-samples are then combined in a joint analysis, treating them as independent observations. In previous works we demonstrated that event types, classified using Machine Learning methods according to their expected angular reconstruction quality, have the potential to significantly improve the CTA angular and energy resolution of a point-like source analysis. Now, we validated the production of event-type wise full-enclosure IRFs, ready to be used with science tools (such as Gammapy and ctools). We will report on the impact of using such an event-type classification on CTA high-level performance, compared to the traditional procedure. © 2023, CC BY.

关键词： Monte Carlo methods

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SPT clusters with DES and HST weak lensing. II. Cosmological constraints from the abundance of massive halos

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Physical Review D 2024年第8期110卷 083510页

作者： S. Bocquet S. Grandis L. E. Bleem M. Klein J. J. Mohr T. Schrabback T. M. C. Abbott P. A. R. Ade M. Aguena A. Alarcon S. Allam S. W. Allen O. Alves A. Amon A. J. Anderson J. Annis B. Ansarinejad J. E. Austermann S. Avila D. Bacon M. Bayliss J. A. Beall K. Bechtol M. R. Becker A. N. Bender B. A. Benson G. M. Bernstein S. Bhargava F. Bianchini M. Brodwin D. Brooks L. Bryant A. Campos R. E. A. Canning J. E. Carlstrom A. Carnero Rosell M. Carrasco Kind J. Carretero F. J. Castander R. Cawthon C. L. Chang C. Chang P. Chaubal R. Chen H. C. Chiang A. Choi T-L. Chou R. Citron C. Corbett Moran J. Cordero M. Costanzi T. M. Crawford A. T. Crites L. N. da Costa M. E. S. Pereira C. Davis T. M. Davis J. DeRose S. Desai T. de Haan H. T. Diehl M. A. Dobbs S. Dodelson C. Doux A. Drlica-Wagner K. Eckert J. Elvin-Poole S. Everett W. Everett I. Ferrero A. Ferté A. M. Flores J. Frieman J. Gallicchio J. García-Bellido M. Gatti E. M. George G. Giannini M. D. Gladders D. Gruen R. A. Gruendl N. Gupta G. Gutierrez N. W. Halverson I. Harrison W. G. Hartley K. Herner S. R. Hinton G. P. Holder D. L. Hollowood W. L. Holzapfel K. Honscheid J. D. Hrubes N. Huang J. Hubmayr E. M. Huff D. Huterer K. D. Irwin D. J. James M. Jarvis G. Khullar K. Kim L. Knox R. Kraft E. Krause K. Kuehn N. Kuropatkin F. Kéruzoré O. Lahav A. T. Lee P.-F. Leget D. Li H. Lin A. Lowitz N. MacCrann G. Mahler A. Mantz J. L. Marshall J. McCullough M. McDonald J. J. McMahon J. Mena-Fernández F. Menanteau S. S. Meyer R. Miquel J. Montgomery J. Myles T. Natoli A. Navarro-Alsina J. P. Nibarger G. I. Noble V. Novosad R. L. C. Ogando Y. Omori S. Padin S. Pandey P. Paschos S. Patil A. Pieres A. A. Plazas Malagón A. Porredon J. Prat C. Pryke M. Raveri C. L. Reichardt J. Roberson R. P. Rollins C. Romero A. Roodman J. E. Ruhl E. S. Rykoff B. R. Saliwanchik L. Salvati C. Sánchez E. Sanchez D. Sanchez Cid A. Saro K. K. Schaffer L. F. Secco I. Sevilla-Noarbe K. Sharon E. Sheldon T. Shin C. Sievers G. Smecher M. Smith T. Somboonpanyakul M. Sommer B. Stalder A. A. Stark J. Stephen V. Straz University Observatory Faculty of Physics Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstraße 25/8 6020 Innsbruck Austria High-Energy Physics Division Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue Chicago Illinois 60637 USA Max Planck Institute for Extraterrestrial Physics Gießenbachstraße 1 85748 Garching Germany Argelander-Institut für Astronomie Auf dem Hügel 71 53121 Bonn Germany Cerro Tololo Inter-American Observatory NSF’s National Optical-Infrared Astronomy Research Laboratory Casilla 603 La Serena Chile School of Physics and Astronomy Cardiff University Cardiff CF24 3YB United Kingdom Laboratório Interinstitucional de e-Astronomia—LIneA Rua Gal. José Cristino 77 Rio de Janeiro Rio de Janeiro—20921-400 Brazil Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall Stanford California 94305 USA Department of Physics Stanford University 382 Via Pueblo Mall Stanford California 94305 USA SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo Park California 94025 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom School of Physics University of Melbourne Parkville Victoria 3010 Australia NIST Quantum Devices Group 325 Broadway Mailcode 817.03 Boulder Colorado 80305 USA Department of Physics University of Colorado Boulder Colorado 80309 USA Institut de Física d’Altes Energies (IFAE) The Barcelona Institute of Science and Technology Campus UAB 08193 Bellaterra (Barcelona) Spain Institute of Cosmology and Gravitation University of Portsmouth Portsmouth

We present cosmological constraints from the abundance of galaxy clusters selected via the thermal Sunyaev-Zel’dovich (SZ) effect in South Pole Telescope (SPT) data with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). The cluster sample is constructed from the combined SPT-SZ, SPTpol ECS, and SPTpol 500d surveys, and comprises 1,005 confirmed clusters in the redshift range 0.25–1.78 over a total sky area of 5200 deg2. We use DES Year 3 weak-lensing data for 688 clusters with redshifts z<0.95 and HST weak-lensing data for 39 clusters with 0.6

关键词： Cosmological parameters Dark energy Large scale structure of the Universe Galaxy clusters

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

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Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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The evolutionary history of 2,658 cancers (vol 578, pg 122, 2020)

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NATURE 2023年第7948期614卷 E42-E42页

作者： Gerstung, Moritz Jolly, Clemency Leshchiner, Ignaty Dentro, Stefan C. Gonzalez, Santiago Rosebrock, Daniel Mitchell, Thomas J. Rubanova, Yulia Anur, Pavana Yu, Kaixian Tarabichi, Maxime Deshwar, Amit Wintersinger, Jeff Kleinheinz, Kortine Vazquez-Garcia, Ignacio Haase, Kerstin Jerman, Lara Sengupta, Subhajit Macintyre, Geoff Malikic, Salem Donmez, Nilgun Livitz, Dimitri G. Cmero, Marek Demeulemeester, Jonas Schumacher, Steven Fan, Yu Yao, Xiaotong Lee, Juhee Schlesner, Matthias Boutros, Paul C. Bowtell, David D. Zhu, Hongtu Getz, Gad Imielinski, Marcin Beroukhim, Rameen Sahinalp, S. Cenk Ji, Yuan Peifer, Martin Markowetz, Florian Mustonen, Ville Yuan, Ke Wang, Wenyi Morris, Quaid D. Spellman, Paul T. Wedge, David C. Van Loo, Peter European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Wellcome Sanger Institute Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany University of Ljubljana Ljubljana Slovenia The Francis Crick Institute London UK Big Data Institute University of Oxford Oxford UK Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Big Data Institute Li Ka Shing Centre University of Oxford Oxford UK University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Department of Applied Mathematics and Theoretical Physics Centre for Mathematical Sciences University of Cambridge Cambridge UK Department of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York NY USA Department of Statistics Columbia University New York NY USA Department of Haematology University of Cambridge Cambridge UK University of Leuven Leuven Belgium Broad Institute of MIT and Harvard Cambridge MA USA Center for Cancer Research Massachusetts General Hospital Charlestown MA USA Department of Pathology Massachusetts General Hospital Boston MA USA Harvard Medical School Boston MA USA Center for Cancer Research Massachusetts General Hospital Boston MA USA Dana-Farber Cancer Institute Boston MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Oxford NIHR Biomedical Research Centre Oxford UK Oxford NIHR Biomedical Research Centre University of Oxford Oxford UK University of Toronto Toronto Ontario Canada Vector Institute Toronto Ontario Canada Vector Institute Toronto ON Canada Department of Computer Science University of Toronto Toronto ON Canada Ontario Institute for Cancer Research Toronto Ontario Canada University of California Los Angeles

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Proceedings of the Frontiers of Retrovirology Conference 2016

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Retrovirology 2016年第1期13卷 1-40页

作者： Irena Zurnic Sylvia Hütter Nicole Stanke Tobias Kern Fabian Lindel Gesche Gerresheim Martin Hamann Erik Müllers Dirk Lindemann Ute Lehmann Juliane Reh Paul Lesbats Peter Cherepanov Melanie Mann Erik Serrao Alan Engelman Claire Da Silva Santos Kevin Tartour Andrea Cimarelli Rya Burdick Jianbo Chen Jaya Sastri Wei-Shau Hu Vinay Pathak Oliver T. Keppler Patrícia de Sousa-Pereira Hanna-Mari Baldauf Marcel Stern Karine Pradeau Sylvia Eiler Nicolas Levy Marc Ruff Sarah Lennon Sarah Cianferani Stéphane Emiliani Vincent Parissi Sylvie Rato Miguel Munoz Angela Ciuffi Antonio Rausell Amalio Telenti Alexander Zhyvoloup Ian Anderson Chen- Hsuin Lee Ariberto Fassati Anat Melamed Delphine Planas Petronela Ancuta Yuwei Zhang Huicheng Chen Annie Bernier Annie Gosselin Janos Kriston-Vizi Robin Ketteler Andy Merritt Charles Bangham Jocelyn Turpin Anthony Rodari Benoit Van Driessche Mathilde Galais Nadége Delacourt Sylvain Fauquenoy Caroline Vanhulle Anna Kula Carine Van Lint Ernst J. Wolvetang Arsène Burny Olivier Rohr Thijs van Montfort Renee van der Sluis Ben Berkhout Dave Speijer Gang Wang Na Zhao Atze T. Das Mirte Scherpenisse Bo Meng Andrzej Rutkowski Lars Dölken Andrew Lever Neil Berry Claire Ham Neil Almond Hoi Ping Mok Nicholas Norton Axel Fun Jack Hirst Mark Wills Chris Hellmund Harriet Groom Thomas Schuster Benedikt Asbach Ralf Wagner Christine Gross Martina Kalmer Andrea K. Thoma-Kress Norbert Donhauser Sebastian Millen Sandra M. Müller-Schmucker Veit Wiesmann Thomas Wittenberg Jan Gettemans Minghua Li Shan-Lu Liu Eric O. Freed Janis Müller Jan Münch Simone Joas Clement Wesley Gnanadurai Edina Lump Christina M. Stürzel Daniel Sauter Frank Kirchhoff Katharina Mack Kathrin Starz Christina Stürzel Xaver Sewald Nasim Motamedi Pradeep Uchil Ruoxi Pi Christin Herrmann Walther Mothes Mark Ladinsky Pamela Bjorkman Jagadish Beloor Priti Kumar Thomas Murooka Thorsten Mempel Michael Brehm Dale Greiner Erica Parrish Nicholas F. Parrish Beatrice H. Hahn Frederic Bibollet-Ruche Ulrike Sauermann Katharina Töpfer Tina Schultheiss Chris Molecular Virology and Gene Therapy Molecular Medicine Leuven Belgium Molecular Virology Technical University Dresden Dresden Germany Center for Regenerative Therapies Dresden Dresden Germany Potsdam University Potsdam Germany The Francis Crick Institute London Great Britain Institute of Clinical and Molecular Virology Friedrich-Alexander-Universität Erlangen-Nuremberg Erlangen Germany Dana Farber Cancer Institute Boston MA United States CIRI Lyon France National Cancer Institute Frederick MD United States Virology Max von Pettenkofer-Institut LMU Munich Munich Germany Institute of Medical Virology University of Frankfurt Frankfurt a. M. Germany German Center for Infection Research Munich Germany Institute of Medical Virology University Hospital Frankfurt Frankfurt a. M. Germany CIBIO/InBIO University of Porto Vairão Portugal Faculty of Sciences University of Porto Porto Portugal Virology Max von Pettenkofer Institute LMU Munich Germany Institute for Medical Virology Frankfurt a. M. Germany Integrative structural Biology IGBMC Illkirch France Institut Pluridisciplinaire Hubert Curien Strasbourg France Institut Cochin Paris France CNRS UMR5234 MFP Lab Bordeaux France Associated International Laboratory (LIA) Microbiology and Immunology CNRS/Université de Bordeaux/Heinrich Pette Institute-Leibniz Institute for Experimental Virology Bordeaux/Hamburg France Institute of Microbiology University Hospital Center and University of Lausanne Lausanne Switzerland Imagine Institute Paris Descartes University Paris France J. Craig Venter Institute La Jolla CA United States Infection University College London London Great Britain Medicine Imperial College London Great Britain Microbiology & Infection University of Montreal Montreal Great Britain CRCHUM Montreal Canada University College London LMCB London Great Britain MRC Technology Centre for Therapeutic Discovery London Great Britain Section of Virology Department of Medicine Imperial Co

Oral presentationsSession 1: Entry & uncoatingO1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replicationIrena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Re... 详细信息

Oral presentations

Session 1: Entry & uncoating

O1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replication

Irena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik Müllers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann

O2 A novel entry/uncoating assay reveals the presence of at least two species of viral capsids during synchronized HIV-1 infection

Claire Da Silva Santos, Kevin Tartour, Andrea Cimarelli

O3 Dynamics of nuclear envelope association and nuclear import of HIV-1 complexes

Rya Burdick, Jianbo Chen, Jaya Sastri, Wei-Shau Hu, Vinay Pathak

O4 Human papillomavirus protein E4 potently enhances the susceptibility to HIV infection

Oliver T. Keppler

Session 2: Reverse transcription & integration

O5 Structure and function of HIV-1 integrase post translational modifications

Karine Pradeau, Sylvia Eiler, Nicolas Levy, Sarah Lennon, Sarah Cianferani, Stéphane Emiliani, Marc Ruff

O6 Regulation of retroviral integration by RNA polymerase II associated factors and chromatin structure

Vincent Parissi

Session 3: Transcription and latency

O7 A novel single-cell analysis pipeline to identify specific biomarkers of HIV permissiveness

Sylvie Rato, Antonio Rausell, Miguel Munoz, Amalio Telenti, Angela Ciuffi

O8 A capsid-dependent integration program linking T cell activation to HIV-1 gene expression

Alexander Zhyvoloup, Anat Melamed, Ian Anderson, Delphine Planas, Janos Kriston-Vizi, Robin Ketteler, Chen-Hsuin Lee, Andy Merritt, Petronela Ancuta, Charles Bangham, Ariberto Fassati

O9 Characterisation of new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Virus genome

Anthony Rodari, Benoit Van Driessche, Mathilde Galais, Nadége Delacourt, Sylv

关键词： Human Immunodeficiency Virus Infection Simian Immunodeficiency Virus Feline Immunodeficiency Virus Bovine Leukemia Virus Prototype Foamy Virus

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