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arXiv 2024年

作者： Aiello, S. Albert, A. Alhebsi, A.R. Alshamsi, M. Garre, S. Alves Ambrosone, A. Ameli, F. Andre, M. Aphecetche, L. Ardid, M. Ardid, S. Atmani, H. Aublin, J. Badaracco, F. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. Becherini, Y. Bendahman, M. Benfenati, F. Benhassi, M. Bennani, M. Benoit, D.M. Berbee, E. Bertin, V. Biagi, S. Boettcher, M. Bonanno, D. Bouasla, A.B. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Breuhaus, M. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Cocimano, R. Coelho, J.A.B. Coleiro, A. Condorelli, A. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. Dallier, R. De Benedittis, A. De Martino, B. De Wasseige, G. Decoene, V. Del Rosso, I. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Drakopoulou, E. Drouhin, D. Ducoin, J.-G. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. El Bojaddaini, I. El Hedri, S. Ellajosyula, V. Enzenhöfer, A. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gagliardini, S. Gal, T. Méndez, J. García Soto, A. Garcia Oliver, C. Gatius Geißelbrecht, N. Genton, E. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goswami, P. Gozzini, S.R. Gracia, R. Guidi, C. Guillon, B. Gutiérrez, M. Haack, C. van Haren, H. Heijboer, A. Hennig, L. Hernández-Rey, J.J. Ibnsalih, W. Idrissi Illuminati, G. Joly, D. de Jong, M. de Jong, P. Jung, B.J. Kistauri, G. Kopper, C. Kouchner, A. Kovalev, Y.Y. Kueviakoe, V. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. Lamoureux, M. Larosa, G. Lastoria, C. Lazo, A. Le Stum, S. Lehaut, G. Lemaître, V. Leonora, E. Lessing, N. Levi, G. Clark, M. Lindsey Longhitano, F. Magnani, F. Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France Khalifa University Department of Physics PO Box 127788 Abu Dhabi0000 United Arab Emirates Aix Marseille Univ CNRS IN2P3 CPPM Marseille France IFIC - Instituto de Física Corpuscular CSIC - Universitat de València c/Catedrático José Beltrán 2 Paterna Valencia46980 Spain INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d’Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain Subatech IMT Atlantique IN2P3 CNRS Nantes Université 4 rue Alfred Kastler - La Chantrerie BP Nantes20722 44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/ Paranimf 1 Gandia46730 Spain University Mohammed V in Rabat Faculty of Sciences 4 av. Ibn Battouta B.P. 1014 RabatR.P. 10000 Morocco Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France Università di Genova Via Dodecaneso 33 Genova16146 Italy INFN Sezione di Genova Via Dodecaneso 33 Genova16146 Italy LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 Boulevard Maréchal Juin Caen14050 France Czech Technical University in Prague Institute of Experimental and Applied Physics Husova 240/5 Prague110 00 Czech Republic Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia INFN Sezione di Bologna v.le C. Berti-Pichat 6/2 Bologna40127 Italy Università di Bologna Dipartimento di Fisica e Astronomia v.le C. Berti-Pichat 6/2 Bologna40127 Italy Un

KM3NeT/ORCA is a water Cherenkov neutrino detector under construction and anchored at the bottom of the Mediterranean Sea. The detector is designed to study oscillations of atmospheric neutrinos and determine the neutrino mass ordering. This paper focuses on an initial configuration of ORCA, referred to as ORCA6, which comprises six out of the foreseen 115 detection units of photo-sensors. A high-purity neutrino sample was extracted, corresponding to an exposure of 433 kton-years. The sample of 5828 neutrino candidates is analysed following a binned log-likelihood method in the reconstructed energy and cosine of the zenith angle. The atmospheric oscillation parameters are measured to be sin2 θ23 = 0.51+0.04−0.05, and ∆m231 = 2.18+0.25−0.35 ×10−3 eV2 ∪{−2.25,−1.76}×10−3 eV2 at 68% CL. The inverted neutrino mass ordering hypothesis is disfavoured with a p-value of 0.25. Copyright © 2024, The Authors. All rights reserved.

关键词： Neutrons

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Interpolation of Instrument Response Functions for the Cherenkov Telescope Array in the Context of pyirf

arXiv

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arXiv 2023年

作者： Dominik, Rune Michael Linhoff, Maximilian Sitarek, Julian Abe, K. Abe, S. Acharyya, A. Adam, R. Aguasca-Cabot, A. Agudo, I. Alfaro, J. Alvarez-Crespo, N. Alves Batista, R. Amans, J.-P. Amato, E. Ambrosino, F. Angüner, E.O. Antonelli, L.A. Aramo, C. Arcaro, C. Arrabito, L. Asano, K. Aschersleben, J. Ashkar, H. Augusto Stuani, L. Baack, D. Backes, M. Balazs, C. Balbo, M. Baquero Larriva, A. Barbosa Martins, V. Barres de Almeida, U. Barrio, J.A. Bastieri, D. Batista, P.I. Batkovic, I. Batzofin, R. Baxter, J. Beck, G. Becker Tjus, J. Beiske, L. Belardinelli, D. Benbow, W. Bernardini, E. Bernete Medrano, J. Bernlöhr, K. Berti, A. Beshley, V. Bhattacharjee, P. Bhattacharyya, S. Bi, B. Biederbeck, N. Biland, A. Bissaldi, E. Blanch, O. Blazek, J. Boisson, C. Bolmont, J. Bonnoli, G. Bordas, P. Bosnjak, Z. Bradascio, F. Braiding, C. Bronzini, E. Brose, R. Brown, A.M. Brun, F. Brunelli, G. Bulgarelli, A. Burelli, I. Burmistrov, L. Burton, M. Bylund, T. Calisse, P.G. Campoy-Ordaz, A. Cantlay, B.K. Capalbi, M. Caproni, A. Capuzzo-Dolcetta, R. Carlile, C. Caroff, S. Carosi, A. Carosi, R. Carrasco, M.-S. Cascone, E. Cassol, F. Castrejon, N. Catalani, F. Cerasole, D. Cerruti, M. Chaty, S. Chen, A.W. Chernyakova, M. Chiavassa, A. Chudoba, J. Coimbra Araujo, C.H. Conforti, V. Conte, F. Contreras, J.L. Cossou, C. Costa, A. Costantini, H. Cristofari, P. Cuevas, O. Curtis-Ginsberg, Z. D'Amico, G. D'Ammando, F. Dadina, M. Dalchenko, M. David, L. Davids, I.D. Dazzi, F. De Angelis, A. de Bony de Lavergne, M. De Caprio, V. De Cesare, G. de Gouveia Dal Pino, E.M. De Lotto, B. De Lucia, M. de Menezes, R. de Naurois, M. de Ona Wilhelmi, E. De Simone, N. de Souza, V. del Peral, L. del Valle, M.V. Delagnes, E. Delgado Giler, A.G. Delgado, C. Dell'aiera, M. Della Ceca, R. Della Valle, M. della Volpe, D. Depaoli, D. Dettlaff, A. Di Girolamo, T. Di Piano, A. Di Pierro, F. Di Tria, R. Di Venere, L. Díaz-Bahamondes, C. Dib, C. Diebold, S. Dima, R. Dinesh, A. Djannati-Ataï, A. Djuvsland, J. TU Dortmund University Department of Physics Otto-Hahn-Straße 4a D-44227 Germany University of Lodz Faculty of Physics and Applied Informatics Pomorska 149/153 Lodz90-236 Poland Department of Physics Tokai University 4-1-1 Kita-Kaname Kanagawa Hiratsuka259-1292 Japan Institute for Cosmic Ray Research University of Tokyo 5-1-5 Kashiwa-no-ha Chiba Kashiwa277-8582 Japan University of Alabama Tuscaloosa Department of Physics and Astronomy Gallalee Hall Box 870324 TuscaloosaAL35487-0324 United States Université Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange France Laboratoire Leprince-Ringuet CNRS IN2P3 École polytechnique Institut Polytechnique de Paris Palaiseau91120 France Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Martí i Franquès 1 Barcelona08028 Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n Granada18008 Spain Pontificia Universidad Católica de Chile Av. Libertador Bernardo O'Higgins 340 Santiago Chile IPARCOS-UCM Instituto de Física de Partículas y del Cosmos EMFTEL Department Universidad Complutense de Madrid MadridE-28040 Spain Instituto de Física Teórica UAM CSIC Departamento de Física Teórica Universidad Autónoma de Madrid c/Nicolás Cabrera 13-15 Campus de Cantoblanco UAM Madrid28049 Spain LUTH GEPI and LERMA Observatoire de Paris Université PSL Université Paris Cité CNRS 5 place Jules Janssen Meudon92190 France INAF - Osservatorio Astrofisico di Arcetri Largo E. Fermi 5 Firenze50125 Italy INAF - Osservatorio Astronomico di Roma Via di Frascati 33 Monteporzio Catone00040 Italy TÜBİTAK Research Institute for Fundamental Sciences Gebze Kocaeli41470 Turkey INFN Sezione di Napoli Via Cintia ed. G Napoli80126 Italy INFN Sezione di Padova Via Marzolo 8 Padova35131 Italy Laboratoire Univers et Particules de Montpellier Université de Montpellier CNRS IN2P3 CC 72 Place Eugène Bataillon Montp

The Cherenkov Telescope Array (CTA) will be the next generation ground-based very-high-energy gamma-ray observatory, constituted by tens of Imaging Atmospheric Cherenkov Telescopes at two sites once its construction and commissioning are finished. Like its predecessors, CTA relies on Instrument Response Functions (IRFs) to relate the observed and reconstructed properties to the true ones of the primary gamma-ray photons. IRFs are needed for the proper reconstruction of spectral and spatial information of the observed sources and are thus among the data products issued to the observatory users. They are derived from Monte Carlo simulations, depend on observation conditions like the telescope pointing direction or the atmospheric transparency and can evolve with time as hardware ages or is replaced. Producing a complete set of IRFs from simulations for every observation taken is a time-consuming task and not feasible when releasing data products on short timescales. Consequently, interpolation techniques on simulated IRFs are investigated to quickly estimate IRFs for specific observation conditions. However, as some of the IRFs constituents are given as probability distributions, specialized methods are needed. This contribution summarizes and compares the feasibility of multiple approaches to interpolate IRF components in the context of the pyirf python software package and IRFs simulated for the Large-Sized Telescope prototype (LST-1). We will also give an overview of the current functionalities implemented in pyirf. © 2023, CC BY-NC-ND.

关键词： Python

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Updated search for spectral lines from Galactic dark matter interactions with pass 8 data from the Fermi Large Area Telescope

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Physical Review D 2015年第12期91卷 122002-122002页

作者： M. Ackermann M. Ajello A. Albert B. Anderson W. B. Atwood L. Baldini G. Barbiellini D. Bastieri R. Bellazzini E. Bissaldi R. D. Blandford E. D. Bloom R. Bonino E. Bottacini T. J. Brandt J. Bregeon P. Bruel R. Buehler S. Buson G. A. Caliandro R. A. Cameron R. Caputo M. Caragiulo P. A. Caraveo C. Cecchi E. Charles A. Chekhtman J. Chiang G. Chiaro S. Ciprini R. Claus J. Cohen-Tanugi J. Conrad A. Cuoco S. Cutini F. D’Ammando A. de Angelis F. de Palma R. Desiante S. W. Digel L. Di Venere P. S. Drell A. Drlica-Wagner C. Favuzzi S. J. Fegan A. Franckowiak Y. Fukazawa S. Funk P. Fusco F. Gargano D. Gasparrini N. Giglietto F. Giordano M. Giroletti G. Godfrey G. A. Gomez-Vargas I. A. Grenier J. E. Grove S. Guiriec M. Gustafsson J. W. Hewitt A. B. Hill D. Horan G. Jóhannesson R. P. Johnson M. Kuss S. Larsson L. Latronico J. Li L. Li F. Longo F. Loparco M. N. Lovellette P. Lubrano D. Malyshev M. Mayer M. N. Mazziotta J. E. McEnery P. F. Michelson T. Mizuno A. A. Moiseev M. E. Monzani A. Morselli S. Murgia E. Nuss T. Ohsugi M. Orienti E. Orlando J. F. Ormes D. Paneque M. Pesce-Rollins F. Piron G. Pivato S. Rainò R. Rando M. Razzano A. Reimer T. Reposeur S. Ritz M. Sánchez-Conde A. Schulz C. Sgrò E. J. Siskind F. Spada G. Spandre P. Spinelli H. Tajima H. Takahashi J. B. Thayer L. Tibaldo D. F. Torres G. Tosti E. Troja G. Vianello M. Werner B. L. Winer K. S. Wood M. Wood G. Zaharijas S. Zimmer Deutsches Elektronen Synchrotron DESY D-15738 Zeuthen Germany Department of Physics and Astronomy Kinard Lab of Physics Clemson University Clemson South Carolina 29634-0978 USA W.W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics and SLAC National Accelerator Laboratory Stanford University Stanford California 94305 USA Department of Physics Stockholm University AlbaNova SE-106 91 Stockholm Sweden The Oskar Klein Centre for Cosmoparticle Physics AlbaNova SE-106 91 Stockholm Sweden Department of Physics and Department of Astronomy and Astrophysics Santa Cruz Institute for Particle Physics University of California at Santa Cruz Santa Cruz California 95064 USA Università di Pisa and Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste I-34127 Trieste Italy Dipartimento di Fisica Università di Trieste I-34127 Trieste Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova I-35131 Padova Italy Dipartimento di Fisica e Astronomia “G. Galilei ” Università di Padova I-35131 Padova Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari 70126 Bari Italy Istituto Nazionale di Fisica Nucleare Sezione di Torino I-10125 Torino Italy Dipartimento di Fisica Generale “Amadeo Avogadro ” Università degli Studi di Torino I-10125 Torino Italy NASA Goddard Space Flight Center Greenbelt Maryland 20771 USA Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 Montpellier France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 Route de Saclay F91128 Palaiseau France Consorzio Interuniversitario per la Fisica Spaziale (CIFS) I-10133 Torino Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica I-20133 Milano Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia I-06123 Perugia Italy Dipartime

Dark matter in the Milky Way may annihilate directly into γ rays, producing a monoenergetic spectral line. Therefore, detecting such a signature would be strong evidence for dark matter annihilation or decay. We search for spectral lines in the Fermi Large Area Telescope observations of the Milky Way halo in the energy range 200 MeV–500 GeV using analysis methods from our most recent line searches. The main improvements relative to previous works are our use of 5.8 years of data reprocessed with the Pass 8 event-level analysis and the additional data resulting from the modified observing strategy designed to increase exposure of the Galactic center region. We search in five sky regions selected to optimize sensitivity to different theoretically motivated dark matter scenarios and find no significant detections. In addition to presenting the results from our search for lines, we also investigate the previously reported tentative detection of a line at 133 GeV using the new Pass 8 data.

关键词： SPECTRAL lines DARK matter (Astronomy) ATOMIC spectra FERMI energy ELECTRONIC structure MILKY Way

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Measurement of the high-energy gamma-ray emission from the Moon with the Fermi Large Area Telescope

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Physical Review D 2016年第8期93卷 082001-082001页

作者： M. Ackermann M. Ajello A. Albert W. B. Atwood L. Baldini G. Barbiellini D. Bastieri R. Bellazzini E. Bissaldi R. D. Blandford R. Bonino E. Bottacini J. Bregeon P. Bruel R. Buehler G. A. Caliandro R. A. Cameron M. Caragiulo P. A. Caraveo E. Cavazzuti C. Cecchi A. Chekhtman J. Chiang G. Chiaro S. Ciprini R. Claus J. Cohen-Tanugi F. Costanza A. Cuoco S. Cutini F. D’Ammando A. de Angelis F. de Palma R. Desiante S. W. Digel L. Di Venere P. S. Drell C. Favuzzi S. J. Fegan W. B. Focke A. Franckowiak S. Funk P. Fusco F. Gargano D. Gasparrini N. Giglietto F. Giordano M. Giroletti T. Glanzman G. Godfrey I. A. Grenier J. E. Grove S. Guiriec A. K. Harding J. W. Hewitt D. Horan X. Hou G. Iafrate G. Jóhannesson T. Kamae M. Kuss S. Larsson L. Latronico J. Li L. Li F. Longo F. Loparco M. N. Lovellette P. Lubrano J. Magill S. Maldera A. Manfreda M. Mayer M. N. Mazziotta P. F. Michelson W. Mitthumsiri T. Mizuno M. E. Monzani A. Morselli S. Murgia E. Nuss N. Omodei E. Orlando J. F. Ormes D. Paneque J. S. Perkins M. Pesce-Rollins V. Petrosian F. Piron G. Pivato S. Rainò R. Rando M. Razzano A. Reimer O. Reimer T. Reposeur C. Sgrò E. J. Siskind F. Spada G. Spandre P. Spinelli H. Takahashi J. B. Thayer D. J. Thompson L. Tibaldo D. F. Torres G. Tosti E. Troja G. Vianello B. L. Winer K. S. Wood M. Yassine F. Cerutti A. Ferrari P. R. Sala Deutsches Elektronen Synchrotron DESY D-15738 Zeuthen Germany Department of Physics and Astronomy Clemson University Kinard Lab of Physics Clemson South Carolina 29634-0978 USA W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics and SLAC National Accelerator Laboratory Stanford University Stanford California 94305 USA Santa Cruz Institute for Particle Physics Department of Physics and Department of Astronomy and Astrophysics University of California at Santa Cruz Santa Cruz California 95064 USA Università di Pisa and Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste I-34127 Trieste Italy Dipartimento di Fisica Università di Trieste I-34127 Trieste Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova I-35131 Padova Italy Dipartimento di Fisica e Astronomia “G. Galilei” Università di Padova I-35131 Padova Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari I-70126 Bari Italy Istituto Nazionale di Fisica Nucleare Sezione di Torino I-10125 Torino Italy Dipartimento di Fisica Generale “Amadeo Avogadro” Università degli Studi di Torino I-10125 Torino Italy Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 F-34095 Montpellier France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 F-91128 Palaiseau Cedex France Consorzio Interuniversitario per la Fisica Spaziale (CIFS) I-10133 Torino Italy Dipartimento di Fisica “M. Merlin” dell’Università e del Politecnico di Bari I-70126 Bari Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica I-20133 Milano Italy Agenzia Spaziale Italiana (ASI) Science Data Center I-00133 Roma Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia I-06123 Perugia Italy Dipartimento di Fisica Università degli Studi di Perugia I-06123 Perugia

We have measured the gamma-ray emission spectrum of the Moon using the data collected by the Large Area Telescope onboard the Fermi satellite during its first seven years of operation, in the energy range from 30 MeV up to a few GeV. We have also studied the time evolution of the flux, finding a correlation with the solar activity. We have developed a full Monte Carlo simulation describing the interactions of cosmic rays with the lunar surface. The results of the present analysis can be explained in the framework of this model, where the production of gamma rays is due to the interactions of cosmic-ray proton and helium nuclei with the surface of the Moon. Finally, we have used our simulation to derive the cosmic-ray proton and helium spectra near Earth from the Moon gamma-ray data.

关键词： Cosmic ray sources Cosmic rays & astroparticles Gamma ray astronomy Solar cycles

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Searching for Dark Matter Annihilation from Milky Way Dwarf Spheroidal Galaxies with Six Years of Fermi Large Area Telescope Data

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Physical Review Letters 2015年第23期115卷 231301-231301页

作者： M. Ackermann A. Albert B. Anderson W. B. Atwood L. Baldini G. Barbiellini D. Bastieri K. Bechtol R. Bellazzini E. Bissaldi R. D. Blandford E. D. Bloom R. Bonino E. Bottacini T. J. Brandt J. Bregeon P. Bruel R. Buehler G. A. Caliandro R. A. Cameron R. Caputo M. Caragiulo P. A. Caraveo C. Cecchi E. Charles A. Chekhtman J. Chiang G. Chiaro S. Ciprini R. Claus J. Cohen-Tanugi J. Conrad A. Cuoco S. Cutini F. D’Ammando A. de Angelis F. de Palma R. Desiante S. W. Digel L. Di Venere P. S. Drell A. Drlica-Wagner R. Essig C. Favuzzi S. J. Fegan E. C. Ferrara W. B. Focke A. Franckowiak Y. Fukazawa S. Funk P. Fusco F. Gargano D. Gasparrini N. Giglietto F. Giordano M. Giroletti T. Glanzman G. Godfrey G. A. Gomez-Vargas I. A. Grenier S. Guiriec M. Gustafsson E. Hays J. W. Hewitt D. Horan T. Jogler G. Jóhannesson M. Kuss S. Larsson L. Latronico J. Li L. Li M. Llena Garde F. Longo F. Loparco P. Lubrano D. Malyshev M. Mayer M. N. Mazziotta J. E. McEnery M. Meyer P. F. Michelson T. Mizuno A. A. Moiseev M. E. Monzani A. Morselli S. Murgia E. Nuss T. Ohsugi M. Orienti E. Orlando J. F. Ormes D. Paneque J. S. Perkins M. Pesce-Rollins F. Piron G. Pivato T. A. Porter S. Rainò R. Rando M. Razzano A. Reimer O. Reimer S. Ritz M. Sánchez-Conde A. Schulz N. Sehgal C. Sgrò E. J. Siskind F. Spada G. Spandre P. Spinelli L. Strigari H. Tajima H. Takahashi J. B. Thayer L. Tibaldo D. F. Torres E. Troja G. Vianello M. Werner B. L. Winer K. S. Wood M. Wood G. Zaharijas S. Zimmer Deutsches Elektronen Synchrotron DESY D-15738 Zeuthen Germany W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics and SLAC National Accelerator Laboratory Stanford University Stanford California 94305 USA Department of Physics Stockholm University AlbaNova SE-106 91 Stockholm Sweden The Oskar Klein Centre for Cosmoparticle Physics AlbaNova SE-106 91 Stockholm Sweden Santa Cruz Institute for Particle Physics Department of Physics and Department of Astronomy and Astrophysics University of California at Santa Cruz Santa Cruz California 95064 USA Università di Pisa and Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste I-34127 Trieste Italy Dipartimento di Fisica Università di Trieste I-34127 Trieste Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova I-35131 Padova Italy Dipartimento di Fisica e Astronomia “G. Galilei” Università di Padova I-35131 Padova Italy Dept. of Physics and Wisconsin IceCube Particle Astrophysics Center University of Wisconsin Madison Wisconsin 53706 USA Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari I-70126 Bari Italy Istituto Nazionale di Fisica Nucleare Sezione di Torino I-10125 Torino Italy Dipartimento di Fisica Generale “Amadeo Avogadro” Università degli Studi di Torino I-10125 Torino Italy NASA Goddard Space Flight Center Greenbelt Maryland 20771 USA Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 Montpellier France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 Palaiseau France Consorzio Interuniversitario per la Fisica Spaziale (CIFS) I-10133 Torino Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica I-20133 Milano Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia I-06123 Perugia Italy Dipartimento di Fisica Uni

The dwarf spheroidal satellite galaxies (dSphs) of the Milky Way are some of the most dark matter (DM) dominated objects known. We report on γ-ray observations of Milky Way dSphs based on six years of Fermi Large Area Telescope data processed with the new Pass8 event-level analysis. None of the dSphs are significantly detected in γ rays, and we present upper limits on the DM annihilation cross section from a combined analysis of 15 dSphs. These constraints are among the strongest and most robust to date and lie below the canonical thermal relic cross section for DM of mass ≲100 GeV annihilating via quark and τ-lepton channels.

关键词： Gamma ray astronomy Particle dark matter Normal galaxies

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Search for extended sources in the galactic plane using 6 years of Fermi-Large area telescope pass 8 data above 10 GeV

arXiv

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arXiv 2017年

作者： Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bellazzini, R. Bissaldi, E. Bloom, E.D. Bonino, R. Bottacini, E. Brandt, T.J. Bregeon, J. Bruel, P. Buehler, R. Cameron, R.A. Caragiulo, M. Caraveo, P.A. Castro, D. Cavazzuti, E. Cecchi, C. Charles, E. Chekhtman, A. Cheung, C.C. Chiaro, G. Ciprini, S. Cohen, J.M. Costantin, D. Costanza, F. Cutini, S. D’Ammando, F. de Palma, F. Desiante, R. Digel, S.W. Di Lalla, N. Di Mauro, M. Di Venere, L. Favuzzi, C. Fegan, S.J. Ferrara, E.C. Franckowiak, A. Fukazawa, Y. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Giglietto, N. Giordano, F. Giroletti, M. Green, D. Grenier, I.A. Grondin, M.-H. Guillemot, L. Guiriec, S. Harding, A.K. Hays, E. Hewitt, J.W. Horan, D. Hou, X. Jóhannesson, G. Kamae, T. Kuss, M. la Mura, G. Larsson, S. Lemoine-Goumard, M. Li, J. Longo, F. Loparco, F. Lubrano, P. Magill, J.D. Maldera, S. Malyshev, D. Manfreda, A. Mazziotta, M.N. Michelson, P.F. Mitthumsiri, W. Mizuno, T. Monzani, M.E. Morselli, A. Moskalenko, I.V. Negro, M. Nuss, E. Ohsugi, T. Omodei, N. Orienti, M. Orlando, E. Ormes, J.F. Paliya, V.S. Paneque, D. Perkins, J.S. Persic, M. Pesce-Rollins, M. Petrosian, V. Piron, F. Porter, T.A. Principe, G. Rainò, S. Rando, R. Razzano, M. Razzaque, S. Reimer, A. Reimer, O. Reposeur, T. Sgrò, C. Simone, D. Siskind, E.J. Spada, F. Spandre, G. Spinelli, P. Suson, D.J. Tak, D. Thayer, J.B. Thompson, D.J. Torres, D.F. Tosti, G. Troja, E. Vianello, G. Wood, K.S. Wood, M. Deutsches Elektronen Synchrotron DESY ZeuthenD-15738 Germany Department of Physics and Astronomy Clemson University Kinard Lab of Physics ClemsonSC29634-0978 United States Università di Pisa Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Laboratoire AIM CEA-IRFU CNRS Université Paris Diderot Service d’Astrophysique CEA Saclay Gif sur YvetteF-91191 France Istituto Nazionale di Fisica Nucleare Sezione di Trieste TriesteI-34127 Italy Dipartimento di Fisica Università di Trieste TriesteI-34127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova PadovaI-35131 Italy Dipartimento di Fisica e Astronomia "G. Galilei" Università di Padova PadovaI-35131 Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari BariI-70126 Italy W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics SLAC National Accelerator Laboratory Stanford University StanfordCA94305 United States Istituto Nazionale di Fisica Nucleare Sezione di Torino TorinoI-10125 Italy Dipartimento di Fisica Università degli Studi di Torino TorinoI-10125 Italy NASA Goddard Space Flight Center GreenbeltMD20771 United States Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 MontpellierF-34095 France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 PalaiseauF-91128 France Dipartimento di Fisica "M. Merlin" dell’Università e del Politecnico di Bari BariI-70126 Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano via E. Bassini 15 MilanoI-20133 Italy Science Data Center RomaI-00133 Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia PerugiaI-06123 Italy Dipartimento di Fisica Università degli Studi di Perugia PerugiaI-06123 Italy College of Science George Mason University Fairfax VA22030 United States Naval Research Laboratory Washi

The spatial extension of a γ-ray source is an essential ingredient to determine its spectral properties as well as its potential multi-wavelength counterpart. The capability to spatially resolve γ-ray sources is greatly improved by the newly delivered Fermi-Large Area Telescope (LAT) Pass 8 event-level analysis which provides a greater acceptance and an improved point spread function, two crucial factors for the detection of extended sources. Here, we present a complete search for extended sources located within 7◦ from the Galactic plane, using 6 years of Fermi-LAT data above 10 GeV. We find 46 extended sources and provide their morphological and spectral characteristics. This constitutes the first catalog of hard Fermi-LAT extended sources, named the Fermi Galactic Extended Source Catalog, which allows a thorough study of the properties of the Galactic plane in the sub-TeV domain. Copyright © 2017, The Authors. All rights reserved.

关键词： Gamma rays

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FANTOM5 CAGE profiles of human and mouse samples

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Scientific Data 2017年第1期4卷 1-10页

作者： Noguchi, Shuhei Arakawa, Takahiro Fukuda, Shiro Furuno, Masaaki Hasegawa, Akira Hori, Fumi Ishikawa-Kato, Sachi Kaida, Kaoru Kaiho, Ai Kanamori-Katayama, Mutsumi Kawashima, Tsugumi Kojima, Miki Kubosaki, Atsutaka Manabe, Ri-Ichiroh Murata, Mitsuyoshi Nagao-Sato, Sayaka Nakazato, Kenichi Ninomiya, Noriko Nishiyori-Sueki, Hiromi Noma, Shohei Saijyo, Eri Saka, Akiko Sakai, Mizuho Simon, Christophe Suzuki, Naoko Tagami, Michihira Watanabe, Shoko Yoshida, Shigehiro Arner, Peter Axton, Richard A. Babina, Magda Kenneth Baillie, J. Barnett, Timothy C. Beckhouse, Anthony G. Blumenthal, Antje Bodega, Beatrice Bonetti, Alessandro Briggs, James Brombacher, Frank Carlisle, Ailsa J. Clevers, Hans C. Davis, Carrie A. Detmar, Michael Dohi, Taeko Edge, B. Albert S. Edinger, Matthias Ehrlund, Anna Ekwall, Karl Endoh, Mitsuhiro Enomoto, Hideki Eslami, Afsaneh Fagiolini, Michela Fairbairn, Lynsey Farach-Carson, Mary C. Faulkner, Geoffrey J. Ferrai, Carmelo Fisher, Malcolm E. Forrester, Lesley M. Fujita, Rie Furusawa, Jun-Ichi Geijtenbeek, Teunis B. Gingeras, Thomas Goldowitz, Daniel Guhl, Sven Guler, Reto Gustincich, Stefano Ha, Thomas J. Hamaguchi, Masahide Hara, Mitsuko Hasegawa, Yuki Herlyn, Meenhard Heutink, Peter Hitchens, Kelly J. Hume, David A. Ikawa, Tomokatsu Ishizu, Yuri Kai, Chieko Kawamoto, Hiroshi Kawamura, Yuki I. Kempfle, Judith S. Kenna, Tony J. Kere, Juha Khachigian, Levon M. Kitamura, Toshio Klein, Sarah Peter Klinken, S. Knox, Alan J. Kojima, Soichi Koseki, Haruhiko Koyasu, Shigeo Lee, Weonju Lennartsson, Andreas MacKay-Sim, Alan Mejhert, Niklas Mizuno, Yosuke Morikawa, Hiromasa Morimoto, Mitsuru Moro, Kazuyo Morris, Kelly J. Motohashi, Hozumi Mummery, Christine L. Nakachi, Yutaka Nakahara, Fumio Nakamura, Toshiyuki Nakamura, Yukio Nozaki, Tadasuke Ogishima, Soichi Ohkura, Naganari Ohno, Hiroshi Ohshima, Mitsuhiro Okada-Hatakeyama, Mariko Okazaki, Yasushi Orlando, Valerio Ovchinnikov, Dmitry A. Passier, Robert Patrikakis, Margaret Pombo, Ana Pradhan-Bhatt, Swati Qin, Xian-Yang Rehli, Michael Rizzu, Patrizia Roy, S Division of Genomic Technologies RIKEN Center for Life Science Technologies Yokohama Kanagawa 230-0045 Japan RIKEN Omics Science Center Yokohama Kanagawa 230-0045 Japan Department of Medicine Karolinska Institutet Stockholm 14186 Sweden Karolinska University Hospital Center for Metabolism and Endocrinology Stockholm 14186 Sweden Scottish Centre for Regenerative Medicine University of Edinburgh 5 Little France Drive Edinburgh EH164UU United Kingdom Department of Dermatology and Allergy Charite University Medicine Berlin Charitéplatz 1 Berlin 10117 Germany Roslin Institute and Royal School of Veterinary Studies University of Edinburgh Edinburgh EH259RG United Kingdom Australian Infectious Diseases Research Centre University of Queensland St Lucia 4072 QLD Australia School of Chemistry and Molecular Biosciences University of Queensland St Lucia 4072 QLD Australia Bio-Rad Laboratories Pty Ltd Hercules 94547 CA United States University of Queensland Diamantina Institute University of Queensland Woolloongabba 4102 QLD Australia IRCCS Fondazione Santa Lucia Via del Fosso di Fiorano 64 Rome 00143 Italy Australian Institute for Bioengineering and Nanotechnology University of Queensland Brisbane St Lucia 4072 QLD Australia Division of Immunology Institute of Infectious Diseases and Molecular Medicine University of Cape Town Anzio Road Observatory 7925 South Africa Immunology of Infectious Diseases Faculty of Health Sciences South African Medical Research Council University of Cape Town Anzio Road 7925 South Africa International Centre for Genetic Engineering and Biotechnology Cape Town Component Anzio Road 7925 South Africa Hubrecht Institute Royal Netherlands Academy of Arts and Sciences Uppsalalaan 8 3584 Netherlands University Medical Centre Utrecht Postbus 85500 Utrecht 3508 Netherlands Genomics Cold Spring Harbor Laboratory Cold Spring Harbor New York 11797 NY United States Institute of Pharmaceutical Sciences ETH Zurich Vladi

In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.

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Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

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Scientific data 2020年第1期7卷 11页

作者： Marcel Schweiker Amar Abdul-Zahra Maíra André Farah Al-Atrash Hanan Al-Khatri Rea Risky Alprianti Hayder Alsaad Rucha Amin Eleni Ampatzi Alpha Yacob Arsano Montazami Azadeh Elie Azar Bannazadeh Bahareh Amina Batagarawa Susanne Becker Carolina Buonocore Bin Cao Joon-Ho Choi Chungyoon Chun Hein Daanen Siti Aisyah Damiati Lyrian Daniel Renata De Vecchi Shivraj Dhaka Samuel Domínguez-Amarillo Edyta Dudkiewicz Lakshmi Prabha Edappilly Jesica Fernández-Agüera Mireille Folkerts Arjan Frijns Gabriel Gaona Vishal Garg Stephanie Gauthier Shahla Ghaffari Jabbari Djamila Harimi Runa T Hellwig Gesche M Huebner Quan Jin Mina Jowkar Renate Kania Jungsoo Kim Nelson King Boris Kingma M Donny Koerniawan Jakub Kolarik Shailendra Kumar Alison Kwok Roberto Lamberts Marta Laska M C Jeffrey Lee Yoonhee Lee Vanessa Lindermayr Mohammadbagher Mahaki Udochukwu Marcel-Okafor Laura Marín-Restrepo Anna Marquardsen Francesco Martellotta Jyotirmay Mathur Gráinne McGill Isabel Mino-Rodriguez Di Mou Bassam Moujalled Mia Nakajima Edward Ng Marcellinus Okafor Mark Olweny Wanlu Ouyang Ana Ligia Papst de Abreu Alexis Pérez-Fargallo Indrika Rajapaksha Greici Ramos Saif Rashid Christoph F Reinhart Ma Isabel Rivera Mazyar Salmanzadeh Karin Schakib-Ekbatan Stefano Schiavon Salman Shooshtarian Masanori Shukuya Veronica Soebarto Mohammad Tahsildoost Federico Tartarini Despoina Teli Priyam Tewari Samar Thapa Maureen Trebilcock Jörg Trojan Ruqayyatu B Tukur Conrad Voelker Yeung Yam Liu Yang Gabriela Zapata-Lancaster Yongchao Zhai Yingxin Zhu Zahra Sadat Zomorodian Building Science Group Karlsruhe Institute of Technology Englerstr. 7 76131 Karlsruhe Germany. marcel.schweiker@kit.edu. WIN-Kolleg Thermal comfort and pain Heidelberg Academy of Sciences and Humanities Karlstr. 4 69117 Heidelberg Germany. marcel.schweiker@kit.edu. Mechanical Engineering Department University of Technology Iraq Al sinaea 10066 Baghdad Iraq. CTC/Department of Civil Engineering Federal University of Santa Catarina Rua João Pio Duarte Silva s/n. Córrego Grande 88.040-901 Florianópolis SC Brazil. School of Architecture and Built Environment German Jordanian University Darat Othman Bdeir 11180 Amman Jordan. Civil and Architectural Engineering Department Sultan Qaboos University Al-Khod P.O. Box: 33 PC: 123 Muscat Oman. Laboratory of Building Technology Department of Architecture Institut Teknologi Bandung Ganesha 10 40132 Bandung Indonesia. Department of Building Physics Bauhaus-University Weimar Coudraystr. 11A 99423 Weimar Germany. Energy & Climate Change Group Faculty of Engineering & Physical Sciences University of Southampton University Road SO17 1BJ Southampton United Kingdom. Welsh School of Architecture Cardiff University King Edward VII Avenue CF10 3NB Cardiff United Kingdom. Department of Architecture Massachusetts Institute of Technology Massachusetts Ave 02139 Cambridge United States of America. Faculty of Engineering Environment and Computing BNE Research Centre Coventry University Gulson road CV1 2JH Coventry United Kingdom. Industrial and Systems Engineering Khalifa University Masdar Campus Building 1B 54224 Abu Dhabi United Arab Emirates. Architecture University of Tehran Kish International Campus Niyayesh St. Mirmohanna Blvd 79416-55665 Kish Iran. Department of Architecture Ahmadu Bello University Zaria Nigeria Samaru Zaria Nigeria. WIN-Kolleg Thermal comfort and pain Heidelberg Academy of Sciences and Humanities Karlstr. 4 69117 Heidelberg Germany. Department of Cognitive and Clinical Neurosci

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge

arXiv

引用

arXiv 2018年

作者： Bakas, Spyridon Reyes, Mauricio Jakab, Andras Bauer, Stefan Rempfler, Markus Crimi, Alessandro Shinohara, Russell Takeshi Berger, Christoph Ha, Sung Min Rozycki, Martin Prastawa, Marcel Alberts, Esther Lipkova, Jana Freymann, John Kirby, Justin Bilello, Michel Fathallah-Shaykh, Hassan M. Wiest, Roland Kirschke, Jan Wiestler, Benedikt Colen, Rivka Kotrotsou, Aikaterini Lamontagne, Pamela Marcus, Daniel Milchenko, Mikhail Nazeri, Arash Weber, Marc-Andr Mahajan, Abhishek Baid, Ujjwal Gerstner, Elizabeth Kwon, Dongjin Acharya, Gagan Agarwal, Manu Alam, Mahbubul Albiol, Alberto Albiol, Antonio Albiol, Francisco J. Alex, Varghese Allinson, Nigel Amorim, Pedro H.A. Amrutkar, Abhijit Anand, Ganesh Andermatt, Simon Arbel, Tal Arbelaez, Pablo Avery, Aaron Azmat, Muneeza Pranjal, B. Bai, Wenjia Banerjee, Subhashis Barth, Bill Batchelder, Thomas Batmanghelich, Kayhan Battistella, Enzo Beers, Andrew Belyaev, Mikhail Bendszus, Martin Benson, Eze Bernal, Jose Bharath, Halandur Nagaraja Biros, George Bisdas, Sotirios Brown, James Cabezas, Mariano Cao, Shilei Cardoso, Jorge M. Carver, Eric N. Casamitjana, Adri Castillo, Laura Silvana Cat, Marcel Cattin, Philippe Cérigues, Albert Chagas, Vinicius S. Chandra, Siddhartha Chang, Yi-Ju Chang, Shiyu Chang, Ken Chazalon, Joseph Chen, Shengcong Chen, Wei Chen, Jefferson W. Chen, Zhaolin Cheng, Kun Choudhury, Ahana Roy Chylla, Roger Clrigues, Albert Colleman, Steven Colmeiro, Ramiro German Rodriguez Combalia, Marc Costa, Anthony Cui, Xiaomeng Dai, Zhenzhen Dai, Lutao Daza, Laura Alexandra Deutsch, Eric Ding, Changxing Dong, Chao Dong, Shidu Dudzik, Wojciech Eaton-Rosen, Zach Egan, Gary Escudero, Guilherme Estienne, Tho Everson, Richard Fabrizio, Jonathan Fan, Yong Fang, Longwei Feng, Xue Ferrante, Enzo Fidon, Lucas Fischer, Martin French, Andrew P. Fridman, Naomi Fu, Huan Fuentes, David Gao, Yaozong Gates, Evan Gering, David Gholami, Amir Gierke, Willi Glocker, Ben Gong, Mingming Gonzlez-Vill, Sandra Grosges, T. Guan, Yuanfang Guo, Sheng Gupta, Sudeep Han, Woo-Sup Han, Il Song Harmuth, Ko Center for Biomedical Image Computing and Analytics University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Institute for Surgical Technology and Biomechanics University of Bern Bern Switzerland Center for MR-Research University Children's Hospital Zurich Zurich Switzerland Support Centre for Advanced Neuroimaging Inselspital Institute for Diagnostic and Interventional Neuroradiology Bern University Hospital Bern Switzerland University Hospital of Zurich Zurich Switzerland Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia United States Image-Based Biomedical Modeling Group Technical University of Munich Munich Germany Icahn School of Medicine Mount Sinai Health System New YorkNY United States Leidos Biomedical Research Inc. Frederick National Laboratory for Cancer Research FrederickMD21701 United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 United States Department of Neurology University of Alabama at Birmingham BirminghamAL United States Department of Diagnostic Radiology University of Texas MD Anderson Cancer Center HoustonTX United States Department of Psychology Washington University St. LouisMO United States Neuroimaging Informatics and Analysis Center Washington University St. LouisMO United States Department of Radiology Washington University St. LouisMO United States Institute of Diagnostic and Interventional Radiology Pediatric Radiology and Neuroradiology University Medical Center Rostock Ernst-Heydemann-Str. 6 Rostock18057 Germany Tata Memorial Centre Homi Bhabha National Institute Mumbai India Shri Guru Gobind Singhji Institute of Engineering and Technology Nanded India NVIDIA Santa Clara

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-phenotype, as their sub-regions are depicted by varying intensity profiles disseminated across multi-parametric magnetic resonance imaging (mpMRI) scans, reflecting varying biological properties. Their heterogeneous shape, extent, and location are some of the factors that make these tumors difficult to resect, and in some cases inoperable. The amount of resected tumor is a factor also considered in longitudinal scans, when evaluating the apparent tumor for potential diagnosis of progression. Furthermore, there is mounting evidence that accurate segmentation of the various tumor sub-regions can offer the basis for quantitative image analysis towards prediction of patient overall survival. This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i.e., 2012-2018. Specifically, we focus on i) evaluating segmentations of the various glioma sub-regions in pre-operative mpMRI scans, ii) assessing potential tumor progression by virtue of longitudinal growth of tumor sub-regions, beyond use of the RECIST/RANO criteria, and iii) predicting the overall survival from pre-operative mpMRI scans of patients that underwent gross total resection. Finally, we investigate the challenge of identifying the best ML algorithms for each of these tasks, considering that apart from being diverse on each instance of the challenge, the multi-institutional mpMRI BraTS dataset has also been a continuously evolving/growing dataset. Copyright © 2018, The Authors. All rights reserved.

关键词： Tumors

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Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

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Scientific data 2021年第1期8卷 242页

作者： Julien Cohen-Adad Eva Alonso-Ortiz Mihael Abramovic Carina Arneitz Nicole Atcheson Laura Barlow Robert L Barry Markus Barth Marco Battiston Christian Büchel Matthew Budde Virginie Callot Anna J E Combes Benjamin De Leener Maxime Descoteaux Paulo Loureiro de Sousa Marek Dostál Julien Doyon Adam Dvorak Falk Eippert Karla R Epperson Kevin S Epperson Patrick Freund Jürgen Finsterbusch Alexandru Foias Michela Fratini Issei Fukunaga Claudia A M Gandini Wheeler-Kingshott Giancarlo Germani Guillaume Gilbert Federico Giove Charley Gros Francesco Grussu Akifumi Hagiwara Pierre-Gilles Henry Tomáš Horák Masaaki Hori James Joers Kouhei Kamiya Haleh Karbasforoushan Miloš Keřkovský Ali Khatibi Joo-Won Kim Nawal Kinany Hagen H Kitzler Shannon Kolind Yazhuo Kong Petr Kudlička Paul Kuntke Nyoman D Kurniawan Slawomir Kusmia René Labounek Maria Marcella Laganà Cornelia Laule Christine S Law Christophe Lenglet Tobias Leutritz Yaou Liu Sara Llufriu Sean Mackey Eloy Martinez-Heras Loan Mattera Igor Nestrasil Kristin P O'Grady Nico Papinutto Daniel Papp Deborah Pareto Todd B Parrish Anna Pichiecchio Ferran Prados Àlex Rovira Marc J Ruitenberg Rebecca S Samson Giovanni Savini Maryam Seif Alan C Seifert Alex K Smith Seth A Smith Zachary A Smith Elisabeth Solana Y Suzuki George Tackley Alexandra Tinnermann Jan Valošek Dimitri Van De Ville Marios C Yiannakas Kenneth A Weber Ii Nikolaus Weiskopf Richard G Wise Patrik O Wyss Junqian Xu NeuroPoly Lab Institute of Biomedical Engineering Polytechnique Montreal Montreal QC Canada. jcohen@polymtl.ca. Functional Neuroimaging Unit CRIUGM Université de Montréal Montreal QC Canada. jcohen@polymtl.ca. Mila - Quebec AI Institute Montreal QC Canada. jcohen@polymtl.ca. NeuroPoly Lab Institute of Biomedical Engineering Polytechnique Montreal Montreal QC Canada. Department of Radiology Swiss Paraplegic Centre Nottwil Switzerland. Centre for Advanced Imaging The University of Queensland Brisbane Australia. Department of Radiology University of British Columbia Vancouver BC Canada. Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology Massachusetts General Hospital Charlestown MA USA. Department of Radiology Harvard Medical School Boston MA USA. Harvard-Massachusetts Institute of Technology Health Sciences & Technology Cambridge MA USA. School of Information Technology and Electrical Engineering The University of Queensland Brisbane Australia. NMR Research Unit Queen Square MS Centre UCL Queen Square Institute of Neurology Faculty of Brain Sciences University College London London UK. Department of Systems Neuroscience University Medical Center Hamburg-Eppendorf Hamburg Germany. Department of Neurosurgery Medical College of Wisconsin Milwaukee WI USA. Aix-Marseille Univ CNRS CRMBM Marseille France. APHM Hopital Universitaire Timone CEMEREM Marseille France. Vanderbilt University Institute of Imaging Science Vanderbilt University Medical Center Nashville TN USA. Department of Computer and Software Engineering Polytechnique Montreal Montreal Canada. CHU Sainte-Justine Research Centre Montreal QC Canada. Centre de Recherche CHUS CIMS Sherbrooke Canada. Sherbrooke Connectivity Imaging Lab (SCIL) Computer Science department Université de Sherbrooke Sherbrooke Canada. Université de Strasbourg CNRS ICube Strasbourg France. UHB - University Hospital Brno and Masaryk University Department of Radiology and Nuclear

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