检索结果-内蒙古大学图书馆

arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： computer vision

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Explainable AI: Definition and attributes of a good explanation for health AI

arXiv

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arXiv 2024年

作者： Kyrimi, Evangelia McLachlan, Scott Wohlgemut, Jared M. Perkins, Zane B. Lagnado, David A. Marsh, William Gimson, Alexander Shafti, Ali Ercole, Ari Banerjee, Amitava Glocker, Ben Schafer, Burkhard Gatsonis, Constantine Grosan, Crina Sent, Danielle Berman, David S. Glass, David O'Regan, Declan P. Letsios, Dimitrios Morrissey, Dylan Pisirir, Erhan Leofante, Francesco Soyel, Hamit Williamson, Jon Grieman, Keri Dube, Kudakwashe Mardsen, Max Nagendran, Myura Tai, Nigel Kostopoulou, Olga Jones, Owain Curzon, Paul Stoner, Rebecca S. Tandle, Sankalp Joshi, Shalmali Mossadegh, Somayyeh Buijsman, Stefan Miller, Tim Madai, Vince Istvan School of Electronic Engineering and Computer Science Queen Mary University of London London United Kingdom School of Nursing Midwifery and Palliative Care King's College London London United Kingdom Centre for Trauma Sciences Blizard Institute Queen Mary University of London London United Kingdom Royal London Hospital Barts Health NHS Trust London United Kingdom Department of Experiment Psychology University College London London United Kingdom Cambridge Liver Unit Addenbrooke's Hospital Cambridge University Hospitals Hills Road Box 210 Cambridge United Kingdom University of Cambridge United Kingdom Cambridge Consultants Ltd. United Kingdom Division of Anaesthesia Cambridge Centre for AI in Medicine University of Cambridge Cambridge United Kingdom Magdelene College University of Cambridge United Kingdom Institute of Health Informatics University College London London United Kingdom Department of Computing Imperial College London London United Kingdom SCRIPT Centre for IT and IP Law School of Law University of Edinburgh United Kingdom Center for Statistical Sciences School of Public Health Brown University Providence United States Research Group Artificial Intelligence HU University of Applied Sciences Utrecht Netherlands Jheronimus Academy of Data Science Tilburg University Eindhoven University of Technology s-Hertogenbosch Netherlands Centre for Theoretical Physics Queen Mary University of London London United Kingdom School of Computing Ulster University Belfast United Kingdom MRC Laboratory of Medical Sciences Imperial College London London United Kingdom Department of Informatics King's College London United Kingdom Physiotherapy Department Barts Health NHS Trust London United Kingdom Sport and Exercise Medicine Queen Mary University of London London United Kingdom School of Electronic Engineering and Computer Science Queen Mary University of London United Kingdom Department of Computing Imperial College London United Kingdom Departmen

Proposals of artificial intelligence (AI) solutions based on increasingly complex and accurate predictive models are becoming ubiquitous across many disciplines. As the complexity of these models grows, transparency and users' understanding often diminish. This suggests that accurate prediction alone is insufficient for making an AI-based solution truly useful. In the development of healthcare systems, this introduces new issues related to accountability and safety. Understanding how and why an AI system makes a recommendation may require complex explanations of its inner workings and reasoning processes. Although research on explainable AI (XAI) has significantly increased in recent years and there is high demand for XAI in medicine, defining what constitutes a good explanation remains ad hoc, and providing adequate explanations continues to be challenging. To fully realize the potential of AI, it is critical to address two fundamental questions about explanations for safety-critical AI applications, such as health-AI: (1) What is an explanation in health-AI? and (2) What are the attributes of a good explanation in health-AI? In this study, we examined published literature and gathered expert opinions through a two-round Delphi study. The research outputs include (1) a definition of what constitutes an explanation in health-AI and (2) a comprehensive list of attributes that characterize a good explanation in health-AI. © 2024, CC BY.

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Roadmap on Deep Learning for Microscopy

arXiv

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arXiv 2023年

作者： Volpe, Giovanni Wählby, Carolina Tian, Lei Hecht, Michael Yakimovich, Artur Monakhova, Kristina Waller, Laura Sbalzarini, Ivo F. Metzler, Christopher A. Xie, Mingyang Zhang, Kevin Lenton, Isaac C.D. Rubinsztein-Dunlop, Halina Brunner, Daniel Bai, Bijie Ozcan, Aydogan Midtvedt, Daniel Wang, Hao Sladoje, Nataša Lindblad, Joakim Smith, Jason T. Ochoa, Marien Barroso, Margarida Intes, Xavier Qiu, Tong Yu, Li-Yu You, Sixian Liu, Yongtao Ziatdinov, Maxim A. Kalinin, Sergei V. Sheridan, Arlo Manor, Uri Nehme, Elias Goldenberg, Ofri Shechtman, Yoav Moberg, Henrik K. Langhammer, Christoph Špačková, Barbora Helgadottir, Saga Midtvedt, Benjamin Argun, Aykut Thalheim, Tobias Cichos, Frank Bo, Stefano Hubatsch, Lars Pineda, Jesus Manzo, Carlo Bachimanchi, Harshith Selander, Erik Homs-Corbera, Antoni Fränzl, Martin de Haan, Kevin Rivenson, Yair Korczak, Zofia Adiels, Caroline Beck Mijalkov, Mite Veréb, Dániel Chang, Yu-Wei Pereira, Joana B. Matuszewski, Damian Kylberg, Gustaf Sintorn, Ida-Maria Caicedo, Juan C. Cimini, Beth A. Bell, Muyinatu Lediju A. Saraiva, Bruno M. Jacquemet, Guillaume Henriques, Ricardo Ouyang, Wei Le, Trang Gómez-De-Mariscal, Estibaliz Sage, Daniel Muñoz-Barrutia, Arrate Lindqvist, Ebba Josefson Bergman, Johanna Department of Physics University of Gothenburg Gothenburg41296 Sweden Dept. IT and SciLifeLab Uppsala University Sweden Department of Electrical and Computer Engineering Boston University BostonMA02215 United States Department of Biomedical Engineering Boston University BostonMA02215 United States Görlitz Germany Department of Renal Medicine Division of Medicine University College London Royal Free Hospital Campus London United Kingdom Artificial Intelligence for Life Sciences CIC Dorset United Kingdom Roche Pharma International Informatics Roche Diagnostics GmbH Mannheim Germany Department of Electrical Engineering and Computer Sciences UC Berkeley United States Technische Universität Dresden Faculty of Computer Science Dresden Germany Max Planck Institute of Molecular Cell Biology and Genetics Center for Systems Biology Dresden Dresden Germany University of Maryland College Park United States Klosterneuburg3400 Austria School of Mathematics and Physics The University of Queensland Brisbane4072 Australia Australian Research Council Centre of Excellence for Engineered Quantum Systems The University of Queensland Brisbane4072 Australia Département d’Optique P. M. Duffieux Institut FEMTO-ST Université Franche-Comté CNRS UMR 6174 Besançon France Department of Electrical and Computer Engineering University of California Los Angeles Los AngelesCA United States Department of Information Technology Uppsala University Sweden Department of Biomedical Engineering Rensselaer Polytechnic Institute TroyNY12180 United States Elephas 1 Erdman Pl. Madison53705 United States University of Wisconsin–Madison Department of Medical Physics MadisonWI53705 United States Department of Molecular and Cellular Physiology Albany Medical College AlbanyNY12208 United States Research Laboratory of Electronics Electrical Engineering and Computer Science Massachusetts Institute of Technology BostonMA United States Center for Nanophase Materials Sciences Oak R

Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep neural networks, and machine learning are all niche terms describing computational methods that have gained a pivotal role in microscopy-based research over the past decade. This Roadmap is written collectively by prominent researchers and encompasses selected aspects of how machine learning is applied to microscopy image data, with the aim of gaining scientific knowledge by improved image quality, automated detection, segmentation, classification and tracking of objects, and efficient merging of information from multiple imaging modalities. We aim to give the reader an overview of the key developments and an understanding of possibilities and limitations of machine learning for microscopy. It will be of interest to a wide cross-disciplinary audience in the physical sciences and life sciences. Copyright © 2023, The Authors. All rights reserved.

关键词： Image enhancement

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Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models

arXiv

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arXiv 2022年

作者： Aubry, Jean-Francois Bates, Oscar Boehm, Christian Pauly, Kim Butts Christensen, Douglas Cueto, Carlos Gélat, Pierre Guasch, Lluis Jaros, Jiri Jing, Yun Jones, Rebecca Li, Ningrui Marty, Patrick Montanaro, Hazael Neufeld, Esra Pichardo, Samuel Pinton, Gianmarco Pulkkinen, Aki Stanziola, Antonio Thielscher, Axel Treeby, Bradley Van't Wout, Elwin Physics for Medicine Paris INSERM U1273 ESPCI Paris PSL University CNRS UMR 8063 France Department of Bioengineering Imperial College London Exhibition Road LondonSW7 2AZ United Kingdom Institute of Geophysics ETH Zürich Sonneggstrasse 5 Zürich8092 Switzerland Department of Radiology Stanford University StanfordCA United States Department of Biomedical Engineering Department of Electrical and Computer Engineering University of Utah United States Department of Surgical Biotechnology Division of Surgery and Interventional Science University College London LondonNW3 2PF United Kingdom Earth Science and Engineering Department Imperial College London London United Kingdom Centre of Excellence IT4Innovations Faculty of Information Technology Brno University of Technology Bozetechova 2 Brno612 00 Czech Republic Graduate Program in Acoustics The Pennsylvania State University University Park PA16802 United States Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill North Carolina State University NC United States Department of Electrical Engineering Stanford University StanfordCA United States Zurich Switzerland Laboratory for Acoustics / Noise control Empa Swiss Federal Laboratories for Materials Science and Technology Dubendorf Switzerland Zurich Switzerland Radiology and Clinical Neurosciences Departments Cumming School of Medicine University of Calgary Canada Department of Applied Physics University of Eastern Finland Kuopio70211 Finland Department of Medical Physics and Biomedical Engineering University College London Gower Street LondonWC1E 6BT United Kingdom Technical University of Denmark Denmark Danish Research Center for Magnetic Resonance Copenhagen University Hospital Hvidovre Denmark Institute for Mathematical and Computational Engineering School of Engineering and Faculty of Mathematics Pontificia Universidad Catolica de Chile Santiago Chile

Computational models of acoustic wave propagation are frequently used in transcranial ultrasound therapy, for example, to calculate the intracranial pressure field or to calculate phase delays to correct for skull distortions. To allow intercomparison between the different modeling tools and techniques used by the community, an international working group was convened to formulate a set of numerical benchmarks. Here, these benchmarks are presented, along with intercomparison results. Nine different benchmarks of increasing geometric complexity are defined. These include a single-layer planar bone immersed in water, a multi-layer bone, and a whole skull. Two transducer configurations are considered (a focused bowl and a plane piston), giving a total of 18 permutations of the benchmarks. Eleven different modeling tools are used to compute the benchmark results. The models span a wide range of numerical techniques, including the finite-difference time-domain method, angular-spectrum method, pseudospectral method, boundary-element method, and spectral-element method. Good agreement is found between the models, particularly for the position, size, and magnitude of the acoustic focus within the skull. When comparing results for each model with every other model in a cross comparison, the median values for each benchmark for the difference in focal pressure and position are less than 10% and 1 mm, respectively. The benchmark definitions, model results, and intercomparison codes are freely available to facilitate further comparisons. Copyright © 2022, The Authors. All rights reserved.

关键词： Bone

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Advancing wetland aboveground biomass mapping: Insights from high-resolution PlanetScope data in the Mississippi River Delta

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Remote Sensing Applications: Society and Environment 2025年 38卷

作者： Mohammadali Hemati Masoud Mahdianpari Hodjat Shiri Fariba Mohammadimanesh Bahram Salehi Jianghua Wu Department of Electrical and Computer Engineering Memorial University of Newfoundland St. John's NL A1C 5S7 Canada C-Core St. John's NL A1B 3X5 Canada Civil Engineering Department Faculty of Engineering and Applied Sciences Memorial University of Newfoundland St. John's NL A1B 3X7 Canada Canada Centre for Remote Sensing Natural Resources Canada 580 Booth Street Ottawa ON K1A 0E4 Canada Department of Environmental Resources Engineering State University of New York College of Environmental Science and Forestry (ESF) NY 13210 USA Environment and Sustainability School of Science and the Environment Memorial University of Newfoundland Corner Brook Newfoundland Canada

Wetland ecosystems are vital for global carbon sequestration and environmental stability, highlighting the importance of accurately estimating aboveground biomass (AGB). This study leverages high-resolution PlanetScope satellite data to map AGB in the dynamic tidal marshes of the Mississippi River Delta (MRD). PlanetScope SuperDove surface reflectance data with 3-m spatial resolution was analyzed using machine learning regression models—Random Forest (RF), Support Vector Machine (SVM), and Artificial Neural Network (ANN)—to estimate AGB during the spring and fall seasons of 2021. Field data collected during these seasons provided the reference samples for creating three datasets: one for spring, one for fall, and a combined multi-temporal dataset. For each machine learning method, three models were developed: two for individual seasons and one multi-temporal model. The study incorporated vegetation-sensitive spectral indices to enhance AGB prediction, and their importance was analyzed across the models. The multi-temporal ANN model achieved the highest accuracy, with an RMSE of 1.96 Mg/ha and an R-squared value of 0.84. Using this model, AGB maps for all seasons were generated, revealing seasonal variations in biomass across the wetlands. These results demonstrate the potential of high-resolution remote sensing data and machine learning models to provide accurate and detailed AGB maps, filling spatial and temporal gaps in biomass data. Using spaceborne high-resolution data to produce wetland AGB maps is essential for informing wetland management and conservation policies, as these maps enable monitoring biomass distribution, prioritizing conservation areas, and assessing the effectiveness of conservation strategies to support biodiversity and climate change mitigation.

关键词： Aboveground biomass Machine learning Mississippi River Delta PlanetScope Tidal marsh Wetland

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Estimation of Body Mass Index from photographs using deep Convolutional Neural Networks

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Informatics in Medicine Unlocked 2021年 26卷

作者： Pantanowitz, A. Cohen, E. Gradidge, P. Crowther, N.J. Aharonson, V. Rosman, B. Rubin, D.M. Biomedical Engineering Research Group School of Electrical & Information Engineering University of the Witwatersrand Johannesburg South Africa CNRS UMR 7178 «Institut Pluridisciplinaire Hubert CURIEN » université de Strasbourg Strasbourg France MRC/Wits Developmental Pathways for Health Research Unit Department of Paediatrics Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa CNRS UMR 7206 «Eco-anthropologie » Muséum National d'Histoire Naturelle Paris France Centre for Exercise Science and Sports Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa Department of Chemical Pathology National Health Laboratory Service and University of the Witwatersrand Johannesburg South Africa School of Computer Science and Applied Mathematics University of the Witwatersrand Johannesburg South Africa

Obesity is an important concern in public health, and Body Mass Index is one of the useful, common and convenient measures. However, Body Mass Index requires access to accurate scales and a stadiometer for measurements, and could be made more convenient through analysis of photographs. It could be applied to photographs comprising more than one individual, leading to population screening. We use Convolutional Neural Networks to determine Body Mass Index from photographs in a study with 161 participants. The relatively low number of participants in the data, a common problem in medicine, is addressed by reducing the information in the photographs by generating silhouette images. We successfully determine Body Mass Index for unseen test data with high correlation between prediction and actual values, with correlation measurements of greater than 0.93 and a mean absolute error of 1.20. © 2021

关键词： Anthropomorphism Body Mass Index computer vision Deep Convolutional Neural Networks Machine learning

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Correction to: A Standards Organization for Open and FAIR Neuroscience: the International Neuroinformatics Coordinating Facility

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Neuroinformatics 2022年第1期20卷 37-38页

作者： Mathew Birdsall Abrams Jan G Bjaalie Samir Das Gary F Egan Satrajit S Ghosh Wojtek J Goscinski Jeffrey S Grethe Jeanette Hellgren Kotaleski Eric Tatt Wei Ho David N Kennedy Linda J Lanyon Trygve B Leergaard Helen S Mayberg Luciano Milanesi Roman Mouček J B Poline Prasun K Roy Stephen C Strother Tong Boon Tang Paul Tiesinga Thomas Wachtler Daniel K Wójcik Maryann E Martone INCF Secretariat Karolinska Institutet Stockholm Sweden. mathew@***. Institute of Basic Medical Sciences University of Oslo Oslo Norway. McGill Centre for Integrative Neuroscience McGill University Montreal QC Canada. Monash Biomedical Imaging Monash University Clayton VIC Australia. McGovern Institute for Brain Research Massachusetts Institute of Technology Cambridge MA USA. Department of Otolaryngology - Head and Neck Surgery Harvard Medical School Boston Boston MA USA. Monash eResearch Centre Monash University Melbourne VIC Australia. Department of Neuroscience School of Medicine University of California San Diego La Jolla CA USA. KTH Royal Institute of Technology School of Electrical Engineering and Computer Science Stockholm Sweden. Centre for Intelligent Signal and Imaging Research Institute of Health and Analytics Universiti Teknologi PETRONAS Perak Malaysia. Department of Psychiatry University of Massachusetts Medical School Worcester MA USA. Serendipitea.World Hasselby Sweden. Nash Family Center for Advanced Circuit Therapeutics Icahn School of Medicine New York NY USA. Institute of Biomedical Technologies National Research Council (CNR) Milan Italy. Department of Computer Science and Engineering Faculty of Applied Sciences University of West Bohemia Pilsen Czech Republic. Montreal Neurological Institute Faculty of Medicine and Health Sciences McGill University Montreal Canada. Computational Neuroscience & Neuroimaging Laboratory School of Bio-Medical Engineering Indian Institute of Technology (BHU) Varanasi UP India. Rotman Research Institute Baycrest Centre Department of Medical Biophysics University of Toronto Toronto ON Canada. Centre for Intelligent Signal and Imaging Research Institute of Health and Analytics Universiti Teknologi PETRONAS Bandar Seri Iskandar Malaysia. Donders Institute for Brain Cognition and Behaviour Radboud University Nijmegen Nijmegen Netherlands. Department of Biology II Ludwig-Maximilians-Univers

A Correction to this paper has been published: https://***/10.1007/s12021-021-09522-x

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Automated control and optimisation of laser driven ion acceleration

arXiv

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arXiv 2023年

作者： Loughran, B. Streeter, M.J.V. Ahmed, H. Astbury, S. Balcazar, M. Borghesi, M. Bourgeois, N. Curry, C.B. Dann, S.J.D. DiIorio, S. Dover, N.P. Dzelzanis, T. Ettlinger, O.C. Gauthier, M. Giuffrida, L. Glenn, G.D. Glenzer, S.H. Green, J.S. Gray, R.J. Hicks, G.S. Hyland, C. Istokskaia, V. King, M. Margarone, D. McCusker, O. McKenna, P. Najmudin, Z. Parisuaña, C. Parsons, P. Spindloe, C. Symes, D.R. Thomas, A.G.R. Treffert, F. Xu, N. Palmer, C.A.J. School of Mathematics and Physics Queen's University Belfast BelfastBT7 1NN United Kingdom Central Laser Facility STFC Rutherford Appleton Laboratory DidcotOX11 0QX United Kingdom Gérard Mourou Center for Ultrafast Optical Science University of Michigan Ann ArborMI48109-2099 United States SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo ParkCA United States Department of Electrical and Computer Engineering University of Alberta EdmontonABT6G1H9 Canada The John Adams Institute for Accelerator Science Imperial College London LondonSW7 2AZ United Kingdom ELI Beamlines Centre Institute of Physics Czech Academy of Sciences Za Radnicí 835 Dolní Břežany252 41 Czech Republic Department of Applied Physics Stanford University StanfordCA94305 United States Department of Physics SUPA University of Strathclyde GlasgowG4 0NG United Kingdom Faculty of Nuclear Sciences and Physical Engineering Czech Technical University in Prague Prague Czech Republic Department of Mechanical Engineering Stanford University StanfordCA94305 United States Institut für Kernphysik Technische Universität Darmstadt Karolinenplatz 5 Darmstadt64289 Germany

The interaction of relativistically intense lasers with opaque targets represents a highly non-linear, multi-dimensional parameter space. This limits the utility of sequential 1D scanning of experimental parameters for the optimisation of secondary radiation, although to-date this has been the accepted methodology due to low data acquisition rates. High repetition-rate (HRR) lasers augmented by machine learning present a valuable opportunity for efficient source optimisation. Here, an automated, HRR-compatible system produced high fidelity parameter scans, revealing the influence of laser intensity on target pre-heating and proton generation. A closed-loop Bayesian optimisation of maximum proton energy, through control of the laser wavefront and target position, produced proton beams with equivalent maximum energy to manually-optimized laser pulses but using only 60% of the laser energy. This demonstration of automated optimisation of laser-driven proton beams is a crucial step towards deeper physical insight and the construction of future radiation sources. © 2023, CC BY.

关键词： Proton beams

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare

arXiv

引用

arXiv 2023年

作者： Lekadir, Karim Feragen, Aasa Fofanah, Abdul Joseph Frangi, Alejandro F. Buyx, Alena Emelie, Anais Lara, Andrea Porras, Antonio R. Chan, An-Wen Navarro, Arcadi Glocker, Ben Botwe, Benard O. Khanal, Bishesh Beger, Brigit Wu, Carol C. Cintas, Celia Langlotz, Curtis P. Rueckert, Daniel Mzurikwao, Deogratias Fotiadis, Dimitrios I. Zhussupov, Doszhan Ferrante, Enzo Meijering, Erik Weicken, Eva González, Fabio A. Asselbergs, Folkert W. Prior, Fred Krestin, Gabriel P. Collins, Gary S. Tegenaw, Geletaw S. Kaissis, Georgios Misuraca, Gianluca Tsakou, Gianna Dwivedi, Girish Kondylakis, Haridimos Jayakody, Harsha Woodruf, Henry C. Mayer, Horst Joachim Aerts, Hugo JWL Walsh, Ian Chouvarda, Ioanna Buvat, Irène Tributsch, Isabell Rekik, Islem Duncan, James Kalpathy-Cramer, Jayashree Zahir, Jihad Park, Jinah Mongan, John Gichoya, Judy W. Schnabel, Julia A. Kushibar, Kaisar Riklund, Katrine Mori, Kensaku Marias, Kostas Amugongo, Lameck M. Fromont, Lauren A. Maier-Hein, Lena Alberich, Leonor Cerdá Rittner, Leticia Phiri, Lighton Marrakchi-Kacem, Linda Donoso-Bach, Lluís Martí-Bonmatí, Luis Cardoso, M. Jorge Bobowicz, Maciej Shabani, Mahsa Tsiknakis, Manolis Zuluaga, Maria A. Bielikova, Maria Fritzsche, Marie-Christine Camacho, Marina Linguraru, Marius George Wenzel, Markus De Bruijne, Marleen Tolsgaard, Martin G. Ghassemi, Marzyeh Ashrafuzzaman, Md Goisauf, Melanie Yaqub, Mohammad Abadía, Mónica Cano Mahmoud, Mukhtar M.E. Elattar, Mustafa Rieke, Nicola Papanikolaou, Nikolaos Lazrak, Noussair Díaz, Oliver Salvado, Olivier Pujol, Oriol Sall, Ousmane Guevara, Pamela Gordebeke, Peter Lambin, Philippe Brown, Pieta Abolmaesumi, Purang Dou, Qi Lu, Qinghua Osuala, Richard Nakasi, Rose Zhou, S. Kevin Napel, Sandy Colantonio, Sara Albarqouni, Shadi Joshi, Smriti Carter, Stacy Klein, Stefan Petersen, Steffen E. Aussó, Susanna Awate, Suyash Raviv, Tammy Riklin Cook, Tessa Mutsvangwa, Tinashe E.M. Rogers, Wendy A. Niessen, Wiro J. Puig-Bosch, Xènia Zeng, Yi Mohammed, Yunusa G. Aquino, Yves Saint James Salahuddin, Zohaib Starmans, Martijn P.A. Department de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain Barcelona Spain DTU Compute Technical University of Denmark Kgs Lyngby Denmark Department of Mathematics and Computer Science Faculty of Science and Technology Milton Margai Technical University Freetown Sierra Leone Center for Computational Imaging & Simulation Technologies in Biomedicine Schools of Computing and Medicine University of Leeds Leeds United Kingdom Cardiovascular Science and Electronic Engineering Departments KU Leuven Leuven Belgium Institute of History and Ethics in Medicine Technical University of Munich Munich Germany Faculty of Engineering of Systems Informatics and Sciences of Computing Galileo University Guatemala City Guatemala Department of Biostatistics and Informatics Colorado School of Public Health University of Colorado Anschutz Medical Campus AuroraCO United States Department of Medicine Women’s College Research Institute University of Toronto Toronto Canada Universitat Pompeu Fabra BarcelonaBeta Brain Research Center Barcelona Spain Department of Computing Imperial College London London United Kingdom School of Biomedical & Allied Health Sciences University of Ghana Accra Ghana Department of Midwifery & Radiography School of Health & Psychological Sciences City University of London United Kingdom Kathmandu Nepal European Heart Network Brussels Belgium Department of Thoracic Imaging University of Texas MD Anderson Cancer Center Houston United States IBM Research Africa Nairobi Kenya Departments of Radiology Medicine and Biomedical Data Science Stanford University School of Medicine Stanford United States Institute for AI and Informatics in Medicine Klinikum rechts der Isar Technical University Munich Munich Germany Department of Computing Imperial College London London United Kingdom Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania United Republic of Ioannina Greece Almaty AI Lab Almaty Kazakhstan

Background: Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. In recent years, concerns have been raised about the clinical, technical, ethical and legal risks associated with healthcare AI. To increase adoption in the real world, it is essential that AI technologies are trusted and accepted by patients, clinicians, health organisations and authorities. This paper describes the FUTURE-AI framework as the first international consensus guideline for trustworthy AI in healthcare. Methods: The FUTURE-AI consortium was founded in 2021 and now comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two-year period, the consortium established guiding principles and best practices for trustworthy and deployable AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. Findings: The FUTURE-AI framework was established based on six guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 30 best practices were defined, addressing technical, clinical, socio-ethical and legal dimensions of trustworthy AI. The recommendations cover the entire lifecycle of healthcare AI, from design, development and validation to regulation, deployment, and monitoring. Interpretation: FUTURE-AI is a structured, risk-informed framework which provides guidance for constructing healthcare AI tools that will be trusted, deployed and adopted in real-world clinical practice. Researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of healthcare AI. Copyright © 2023, The Authors. All rights

关键词： Clinical research

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