High-fidelity(HiFi)sequencing has facilitated the assembly and analysis of the most repetitive region of the genome,the ***,our current understanding of human centromeres is based on a relatively small number of telom...
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High-fidelity(HiFi)sequencing has facilitated the assembly and analysis of the most repetitive region of the genome,the ***,our current understanding of human centromeres is based on a relatively small number of telomere-to-telomere assemblies,which have not yet captured its full *** this study,we investigated the genomic diversity of human centromere higher order repeats(HORs)via both HiFi reads and haplotype-resolved assemblies from hundreds of samples drawn from ongoing pangenome-sequencing projects and reprocessed them via a novel HOR annotation pipeline,*** used this wealth of data to provide a global survey of the centromeric HOR landscape;in particular,we found that 23 HORs presented significant copy number variability between *** detected three centromere genotypes with unbalanced population frequencies on chromosomes 5,8,and *** inter-assembly comparison of HOR loci further revealed that while HOR array structures are diverse,they nevertheless tend to form a number of specific landscapes,each exhibiting different levels of HOR subunit expansion and possibly reflecting a cyclical evolutionary transition from homogeneous to nested structures and back.
作者：
Srivastava, JyotiRoutray, SidheswarSchool of Engineering
Indrashil University Department of Computer Science and Engineering Gujarat Rajpur Mehsana India Ganpat University
Faculty of Engineering and Technology Department of Computer Engineering Gujarat Kherwa Mehsana India School of Technology
Pandit Deendayal Energy University Department of Computer Science and Engineering Gandhinagar382007 India
Cyber Physical System (CPS) enhances the functionality of various cyber and physical equipment of Smart Healthcare System (SHS) and provides automation in the healthcare sector using Artificial Intelligence (AI) techn...
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This pilot study focuses on employment of hybrid LMS-ICA system for in-vehicle background noise *** vehicles are nowadays increasingly supporting voice commands,which are one of the pillars of autonomous and SMART ***...
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This pilot study focuses on employment of hybrid LMS-ICA system for in-vehicle background noise *** vehicles are nowadays increasingly supporting voice commands,which are one of the pillars of autonomous and SMART *** speaker recognition for context-aware in-vehicle applications is limited to a certain extent by in-vehicle back-ground *** article presents the new concept of a hybrid system which is implemented as a virtual *** highly modular concept of the virtual car used in combination with real recordings of various driving scenarios enables effective testing of the investigated methods of in-vehicle background noise *** study also presents a unique concept of an adaptive system using intelligent clusters of distributed next generation 5G data networks,which allows the exchange of interference information and/or optimal hybrid algorithm settings between individual *** average,the unfiltered voice commands were successfully recognized in 29.34%of all scenarios,while the LMS reached up to 71.81%,and LMS-ICA hybrid improved the performance further to 73.03%.
Fairness in image restoration tasks is the desire to treat different sub-groups of images equally well. Existing definitions of fairness in image restoration are highly restrictive. They consider a reconstruction to b...
Educational institutions face inherent uncertainties in student performance, stakeholder priorities, and data analysis. This paper explores how cloud computing, with its data storage, analytics, and collaboration tool...
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High mobile phone usage and internet access on phones make it simple to connect to the globe and share your thoughts, feelings, and views on local or global issues on social media. This social media content helps gove...
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In order to improve the operational strength and control precision of the DC motor, a double closed-loop control system based on TAIXIN TX8C1010 MCU is proposed. The single chip is based on a high-speed 8051 core, whi...
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Artificial intelligence (AI) is one of the key technologies transforming our lives, while the transfer of knowledge and competencies from the academic sphere to the industry and real-world use cases are accelerating y...
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This article introduces an open-source software stack designed for autonomous 1:10 scale model *** developed for the Bosch Future Mobility Challenge(BFMC)student competition,this versatile software stack is applicable...
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This article introduces an open-source software stack designed for autonomous 1:10 scale model *** developed for the Bosch Future Mobility Challenge(BFMC)student competition,this versatile software stack is applicable to a variety of autonomous driving *** stack comprises perception,planning,and control modules,each essential for precise and reliable scene understanding in complex environments such as a miniature smart city in the context of *** the limited computing power of model vehicles and the necessity for low-latency real-time applications,the stack is implemented in C++,employs YOLO Version 5 s for environmental perception,and leverages the state-of-the-art Robot Operating System(ROS)for inter-process *** believe that this article and the accompanying open-source software will be a valuable resource for future teams participating in autonomous driving student *** work can serve as a foundational tool for novice teams and a reference for more experienced *** code and data are publicly available on GitHub.
The extraction of information from unstructured text has become a crucial task in the biomedical literature field. Specifically, the analysis of various relationships such as Drug Food, Drug Disease, Drug non-prescrip...
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