Character recognition from handwritten images is of great interest in the pattern recognition research community for their good application in many areas. To implement the system, it requires two steps, viz., feature ...
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Recently, reported a comments on the our paper [Appl. Phys. Lett. 119, 142102(2021)]. With our response, the APL journal rejected their non scientificcomments. There are some ambiguities about their claim: 1-They can ...
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Background and Objective: Accurate lung tumor segmentation is crucial for early clinical diagnosis and subsequent treatment planning for patients. Conducting centralized training to enhance model performance is imprac...
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Background and Objective: Accurate lung tumor segmentation is crucial for early clinical diagnosis and subsequent treatment planning for patients. Conducting centralized training to enhance model performance is impractical in real-world scenarios. Although federated learning offers a promising solution to this issue, effectively and efficiently utilizing unlabeled data remains a challenge. Methods: In this work, we propose a novel federated semi-supervised learning framework (FSSL) for complex and realistic scenario, which can efficiently leverage the limited labeled data and abundant unlabeled data from multiple clinical sites. Specifically, we initially conduct federated self-supervised pre-training at completely unlabeled sites using masked image modeling strategy. Subsequently, in the fine-tuning stage, we propose a pseudo supervision refinement strategy to leverage the unlabeled data from partially labeled sites, which not only reduces pseudo label noise but also helps stabilize the training process. Moreover, we propose a dynamic model aggregation strategy to assist the server in dynamically combining all local models during communication round. Results: We conducted extensive comparative and ablation experiments to validate the effectiveness of our proposed method. When only a limited amount of labeled data is available in the partially labeled sites, even without loading the pre-trained model, our approach consistently achieves the highest average Dice scores of 0.7383, 0.4768, and 0.6629 on the internal test sets, external unseen test sets, and pre-training test sets, respectively. Upon loading the pre-trained model, the scores on the three test sets further improve to 0.8205, 0.6185, and 0.7334, respectively. Conclusion: Our proposed method is capable of collaboratively training a global model with robust segmentation performance and generalizability by efficiently utilizing unlabeled data from different sites, even when only a limited amount of labeled da
Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. Thi...
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Accurate lung tumor segmentation is crucial for early clinical diagnosis and subsequent treatment planning for patients. Centralized model training faces privacy constraints, although federated learning offers a promi...
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This paper introduces a quantum-inspired framework with the bat optimization algorithm for automatic clustering of image datasets. The aim of this work is to find out the optimal number of clusters from an image datas...
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In present era, both soft computing and artificial intelligence techniques have been implemented as problem solver in bioinformatics, as conventional methods are not sufficient for handling huge amount of data. The pr...
ISBN:
(数字)9781728148892
ISBN:
(纸本)9781728148908
In present era, both soft computing and artificial intelligence techniques have been implemented as problem solver in bioinformatics, as conventional methods are not sufficient for handling huge amount of data. The principal focus of research in all pharmaceutical industries is on human proteins like G protein-coupled receptors (GPCRs), ATP-binding cassette (ABC) transporter etc. Membrane protein plays a significant role for every human being and all drug targets have been considered using this protein. In this manuscript, our focal point of research is on membrane protein that is GPCR family and cholesterol target process on the transmembrane region. Among all living organisms, GPCR acts as the largest superfamily and it includes numerous classes. From the last decades to till date GPCR sequence prediction and classification have been a challenging factor for all biomedicine scientists. GPCR family is also known as 7-pass transmembrane protein receptors. Every time membrane cholesterol has targets for the binding sites of membrane protein in both N terminus and C terminus of the cell membrane. For this purpose, a computational Rough-Fuzzy C-Means (FCM) based approach is implemented for prediction and this method helps to find out valid amino acid sequence which has biological relevance for clinical drug discovery.
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