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AIAA science and Technology Forum and Exposition, AIAA SciTech Forum 2025

作者： Hatashita, Luis H. Jain, Suhas S. Daniel Guggenheim School of Aerospace Engineering Flow Physics and Computational Science Lab Georgia Institute of Technology 270 Ferst Drive NW Atlanta30332 Georgia George W. Woodruff School of Mechanical Engineering Flow Physics and Computational Science Lab Georgia Institute of Technology 801 Ferst Drive NW Atlanta30332 Georgia

ISBN: (数字)9781624107238

ISBN: (纸本)9781624107238

Classical diffuse interface methods for non-equilibrium formulations of two-phase flows are not capable of preserving interface-thickness. Furthermore, when coupled with shockcapturing schemes, the interface may diffuse in its entirety. Thus, it is of utmost importance for accurate simulation of two-phase flows to describe interface-preserving formulations. Herein, a conservative interface-regularization formulation based on the phase-field method is proposed, and it analytically guarantees boundedness of volume fraction, absence of spurious oscillations of phasic kinetic energy and mixture entropy preservation in the absence of relaxation. The formulation is shown to stabilize dispersion errors originated due to the interface jumps and to preserve interface thickness when discretized with low lost and low dissipation second-order schemes. A possible issue with this formulation and discretization is the possibility of failing to preserve positivity of quantities of interests, hence, a blending strategy with a Lax-Friedrichs flux is also proposed and tested. In highly compressible scenarios such as shock-drop interaction, the interface regularization when applied to the positive-preserving flux is demonstrated to improve qualitative results on coarser grids. © 2025, American Institute of Aeronautics and Astronautics Inc, AIAA. All rights reserved.

关键词： Kinetic energy

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Accurate calculation of bubble and droplet properties in diffuse-interface two-phase simulations

arXiv

引用

arXiv 2025年

作者： Nathan, Pranav J. Jain, Suhas S. Flow Physics and Computational Science Lab George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology AtlantaGA United States

In this paper, we address the challenge of accurately calculating droplet/bubble properties (e.g., volume, number) in diffuse-interface two-phase flow simulations. Currently, flood-fill algorithms can truncate a significant portion of the volume of droplets/bubbles contained within the diffuse interface region or artificially merge multiple droplets/bubbles. This error is also dependent on the volume fraction cutoff value, which is typically chosen to be 0.5 arbitrarily, in the flood-fill algorithms. We propose a simple volume-correction approach that incorporates an analytical approximation of the truncated volume to correct for the missing droplet/bubble volumes. This proposed method results in accurately recovering the dispersed phase volumes with minimal volume error over a wide range of volume fraction cutoff values;and hence, can also accurately recover the number of droplets/bubbles. This can be a valuable tool for accurate calculation of drop/bubble size distributions for analysis and for Eulerian-to-Lagrangian conversion of the dispersed phase in multi-scale modeling approaches. © 2025, CC BY.

关键词： Two phase flow

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Stationary states of forced two-phase turbulence

arXiv

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arXiv 2025年

作者： Jain, Suhas S. Elnahhas, Ahmed Flow Physics and Computational Science Lab George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology GA United States Center for Turbulence Research Stanford University CA United States

In this work, we perform numerical simulations of forced two-phase isotropic turbulence to study the stationary states of a two-phase mixture. We first formulate three different approaches to force a two-phase turbulent flow that maintains a constant (a) mixture kinetic energy, (b) mixture kinetic energy + surface energy, and (c) individual phase kinetic energy, and study their effect on the final stationary state of the system. We show that forcing the two-phase system eliminates the arbitrariness associated with the initialization of the second phase in two-phase turbulence simulations. Next, we study the global statistics of the two-phase mixture in the stationary state for varying density ratios (10−3 to 103) and viscosity ratios (10−3 to 103), void fraction (dilute to dense regimes), and Weber numbers (breakup and non-breakup regimes). We utilize a spatial filtering approach, that is applicable for the general case of incompressible/compressible two-phase flows, to compute the energy spectra of each of the phases and study the turbulent kinetic energy distribution across scales. We find that the interface behaves as a soft wall, inhibiting the accommodation of eddies inside the dispersed phase. Finally, we show that bubbles and drops exhibit different turbulent characteristics for the same global conditions of the carrier phase, with bubbles exhibiting higher turbulent intensities inside them and droplets behaving ballistically, similar to solid particles. This study acts as a foundational work on stationary two-phase turbulence, which can be used for further analysis and the development of subgrid-scale models for larger-scale simulations of two-phase turbulent flows. © 2025, CC BY.

关键词： Wakes

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18th European Symposium on Radiopharmacy and Radiopharmaceuticals Salzburg, Austria. 7-10 April 2016

引用

EJNMMI RADIOPHARMACY AND CHEMISTRY 2016年第1期1卷 1-37页

作者： [Anonymous] Los Alamos National Laboratory Los Alamos USA Oak Ridge National Laboratory Oak Ridge USA Department of Nuclear Medicine Medical University Innsbruck Innsbruck Austria Department of Radiology & Nuclear Medicine Radboud University Medical Center Nijmegen The Netherlands Institute of Molecular and Translational Medicine Faculty of Medicine and Dentistry Palacky University Olomouc Czech Republic Département de Médecine Nucléaire et Radiobiologie Faculté de Médecine et Sciences de la Santé Université de Sherbrooke Sherbrooke Canada Centre d’Imagerie Moléculaire de Sherbrooke (CIMS) CR-CHUS Sherbrooke Canada Division of Molecular Biology/Biocenter Medical University Innsbruck Innsbruck Austria Department of Nuclear Medicine Radboud University Medical Center Nijmegen The Netherlands IENI-CNR Padua Italy DiSCOG-University of Padua Padua Italy IOV Padua Padua Italy IC-CNR Bari Italy IBB-CNR Naples Italy Laboratory of Radiopharmacy KU Leuven Leuven Belgium Micro Flow Chemistry & Process Technology Chemical Engineering and Chemistry Department TU Eindhoven Eindhoven The Netherlands Laboratory for Radiopharmacy University of Leuven Leuven Belgium Department of Nuclear Medicine and Molecular Imaging University of Leuven Leuven Belgium Department of Medicine and Surgery Tecnomed Foundation University of Milano-Bicocca Milan Italy Dipartimento di Biotecnologie Mediche e Medicina Traslazionale Università degli Studi di Milano Milan Italy Department of Radiology & Nuclear Medicine VU University Medical Center Amsterdam The Netherlands Department of Clinical Pharmacology & Pharmacy VU University Medical Center Amsterdam The Netherlands Université de Lorraine Vandoeuvre les Nancy France NancycloTEP Plateforme d’imagerie expérimentale Vandoeuvre les Nancy France CNRS UMR 7565 SRSMC Vandoeuvre les Nancy France CHU de Nancy-Brabois Vandoeuvre les Nancy France Department of Biomedical Imaging and Image-guided Therapy Division of Nuclear Medicine Medical Univers

Table of contents OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. Fassbender OP04 Comparison of [68Ga]FSC(succ-RGD)3 and [68Ga]NODAGA-RGD for PET imaging of alpha v beta 3 integrin expression Chuangyan Zhai, Gerben M. Franssen, Milos Petrik, Peter Laverman, Clemens Decristoforo OP05 A new NPY-Y1R targeting peptide for breast cancer PET imaging Ait-Mohand Samia, Dumulon-Perreault Veronique, Guerin Brigitte OP06 The influence of multivalency on CCK 2 receptor targeting D. Summer, A. Kroess, C. Rangger, H. Haas, P. Laverman, F. Gerben, E. von Guggenberg, *** OP07 SPECT Imaging of alpha v beta 3 Expression by [99mTc(N)PNP43]- Bifunctional Chimeric RGD Peptide not Cross-Reacting with alpha v beta 5 Cristina Bolzati, Nicola Salvarese, Fiorenzo Refosco, Laura Melendez-Alafort, Debora Carpanese, Antonio Rosato, Michele Saviano, Annarita Del Gatto, Daniela Comegna, Laura Zaccaro OP09 New dienophiles for the inverse-electron-demand Diels-Alder reaction and for pretargeted PET imaging Emilie Billaud, Muneer Ahamed, Frederik Cleeren, Elnaz Shahbazali, Tim Noel, Volker Hessel, Alfons Verbruggen and Guy Bormans OP10 New complexing agent for Al18F-labelling of heat-sensitive biomolecules: Synthesis and preclinical evaluation of Al18F-RESCA1-HAS Cleeren F, Lecina J, Koole M, Verbruggen A and Bormans G OP11 A novel versatile precursor efficient for F-18 radiolabelling via click-chemistry B. Lugatoa, S. Stucchia, E.A. Turollaa, L. Giulianoa, ***, P. Ferraboschib OP12 A general applicable method to quantify unidentified UV impurities in radiopharmaceuticals R.P. Klok, M.P.J. Mooijer, N.H. Hendrikse, A.D. Windhorst OP13 Development of [F-18]Fluoro-C-glycosides to radiolabel peptides Collet C., Petry N., Chretien F., Karcher G., Pellegrini-Moise N., Lamande-Langle S. OP14 A Microfluidic Approach for the 68

关键词： Positron Emission Tomography Single Photon Emission Compute Tomography Standard Uptake Value Positron Emission Tomography Imaging High Pressure Liquid Chromatography

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