检索结果-内蒙古大学图书馆

Advanced preparedness for drinking water emergency: Ensuring safe microbial quality with rapid microbial source tracking and E. coli methods

引用

Environmental Advances 2023年 13卷

作者： Lancaster, Emma Lee, Jiyoung Division of Environmental Health Sciences College of Public Health The Ohio State University Columbus OH United States Environmental Sciences Graduate Program The Ohio State University Columbus OH United States Department of Food Science & Technology The Ohio State University Columbus OH United States Infectious Diseases Institute The Ohio State University Columbus OH United States

The increasing occurrence of water main breaks attributed to aging water infrastructure and other disaster-related events amplifies the risk of microbial contamination in drinking water. Conventional methods for assessing water quality after waterline disruptions involve using time-consuming fecal indicator culture-based techniques that fail to detect the sources of contamination. Thus, rapid emergency responses are critically needed to safeguard public health and swiftly resume community functioning. This novel study proposes a rapid emergency response method targeting Escherichia coli (E. coli) and microbial source tracking (MST, human (HF183) and universal (UniBac) fecal contamination) following water main breaks to evaluate water safety. Objectives were: develop a rapid method for quantifying fecal microbial contamination using droplet digital PCR (ddPCR), and compare rapid results to culture-based method. Results indicate zero E. coli presence using culture-methods. Conversely, results using rapid-ddPCR method show quantifiable positive detection of E. coli and MST markers (HF183 and UniBac) across various sites, suggesting potential widespread fecal contamination following the main break incident. Results highlight that a rapid molecular E. coli and MST techniques effectively detected fecal contamination in treated drinking water that culture-based methods failed to detect. Notably, the ddPCR method produced sensitive results 18 hours faster than culture-based method, highlighting that MST can be used to simultaneously determine water quality and fecal contamination sources. To our knowledge, this is the first pilot study employing highly specific and sensitive MST methodology in treated drinking water following distribution main break. © 2023 The Authors

关键词： E. coli method Main breaks Microbial source tracking Rapid water quality Water contamination Water emergency

来源：评论

学校读者我要写书评

暂无评论

Digitizing Farmers' Land Data Collection Systems in Indonesia with the Use of Tani Millenial Apps

Digitizing Farmers' Land Data Collection Systems in Indonesi...

引用

International Conference on Cybernetics and Intelligent System (ICORIS)

作者： Mohammad Prasanto Bimantio Dian Pratama Putra Teddy Suparyanto Amallia Ferhat Nanda Satya Nugraha Alam Ahmad Hidayat Bens Pardamean Department of Food and Agricultural Technology Institute of Agriculture STIPER Yogyakarta Indonesia Department of Agrotechnology Institute of Agriculture STIPER Yogyakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Department of Agricultural Socio-Economics Institute of Agriculture STIPER Yogyakarta Indonesia Department of Forestry Institute of Agriculture STIPER Yogyakarta Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (纸本)9781665453967

In this era of digital world information, farmers face challenges about information management of huge data and the complexity of processes in precision farming. The data collection carried out so far can cause several difficulties, especially if the data is needed by the government or academics to support decision-making. Agricultural data collection applications only cover 12% of the market share of Android-based agriculture-based applications. In this study, Tani Milenial application is present as an alternative to support agricultural data collection activities in Indonesia. This application encourages farmers to be active and contribute independently to their role as subjects of agricultural development and is accustomed to digitally recording their agricultural activities. In this developed application system, the community, especially farmers and farmer groups, will find it easier to get information about agricultural potential data around where they carry out agricultural activities and can access this information online. Tani Milenial works as a guide to help farmers and transform agriculture but still have some gaps which should be checked and removed. The data collected can be used by various parties for research and decision-making. The app can be further improved to develop new features related to education, market information, and goods.

关键词： Decision making Education Government Transforms Data collection Agriculture Recording

来源：评论

学校读者我要写书评

暂无评论

Exploring Morchella esculenta polysaccharide extracts: In vitro digestion, fermentation characteristics, and prebiotic potential for modulating gut microbiota and function

引用

International Journal of Biological Macromolecules 2025年第PT 1期318卷 144910页

作者： Bingshu Liu Putsawee Tomtong Suvimol Charoensiddhi Wanwipa Vongsangnak Interdisciplinary Graduate Program in Bioscience Faculty of Science Kasetsart University Bangkok 10900 Thailand Department of Food Science and Technology Faculty of Agro-Industry Kasetsart University Bangkok 10900 Thailand Department of Zoology Faculty of Sciences Kasetsart University Bangkok 10900 Thailand Omics Center for Agriculture Bioresources Food and Health Kasetsart University (OmiKU) Bangkok 10900 Thailand

Morchella esculenta , a nutritious and medicinal edible mushroom, has gained an increasing attention due to the bioactive properties of its polysaccharides. This study employed in vitro simulated human digestion and fecal fermentation models to evaluate the effects of M. esculenta polysaccharide on gut microbiota composition and short-chain fatty acids (SCFAs) production. Additionally, a relationship between M. esculenta polysaccharide composition, gut microbiota, and functional role was constructed to elucidate their interactions. The results revealed that 44.87 % of M. esculenta polysaccharide was digested, leading to a reduction in molecular weight and alterations in monosaccharide composition, including decreased glucose and increased galactose and mannose. Fermentation of M. esculenta polysaccharide significantly enhanced SCFAs production and promoted the growth of beneficial gut bacteria, such as Bacteroides, Collinsella, and Bifidobacterium , while notably reducing Ruminococcus torques . Carbohydrate metabolism was enriched in Collinsella and Bifidobacterium which positively correlated with SCFAs biosynthesis e.g., propanoate and butanoate biosynthesis. These findings provide valuable insights into M. esculenta polysaccharide as prebiotic potential, highlighting its functional role in modulating gut microbiota and promoting gut health.

关键词： Dietary polysaccharide Gut microbiota Morchella esculenta Mushroom Short-chain fatty acids

来源：评论

学校读者我要写书评

暂无评论

A first-principles study on the quantum tunneling of methylhydroxycarbene isomerization in various solvents 4

A first-principles study on the quantum tunneling of methylh...

引用

4th Padjadjaran International Physics Symposium 2019, PIPS 2019

作者： Susanti, E.D. Rusydi, F. Puspitasari, I. Fadilla, R.N. Aisyah, N.D. Ahmad, A. Research Center for Quantum Engineering Design Faculty of Science and Technology Universitas Airlangga Jl. Mulyorejo Surabaya60115 Indonesia Department of Physics Faculty of Science and Technology Universitas Airlangga Jl. Mulyorejo Surabaya60115 Indonesia Precision Sciences and Technology and Applied Physics Graduate School of Engineering Osaka University Suita565-0871 Japan Information System Study Program Faculty of Science and Technology Universitas Airlangga Jl. Mulyorejo Surabaya60115 Indonesia School of Chemical Science and Food Technology Faculty of Science and Technology Universiti Kebangsaan Malaysia Bangi Selangor43600 Malaysia

Quantum tunneling phenomenon allows a high-barrier reaction to occur even though thermal energy is not sufficient to surmount the barrier. The phenomenon has been suggested to exist in the isomerization of methylhydroxycarbene which occured at 11 K. Here we study the quantum tunneling that occured in the isomerization of methylhydroxycarbene to acetaldehyde and to vinyl alcohol based on density functional calculations. The isomerization pathways are determined under the effect of various solvents which are modeled by polarizable continuum model (PCM). We use Wentzel-Kramers-Brillouin (WKB) approximation to calculate the tunneling probability (T) and extend the usefulness of T into isomerization rate. The results show that the solvents give a significant effect on the isomerization rate of methylhydroxycarbene to acetaldehyde but an insignificant one on the isomerization rate to vinyl alcohol. © 2020 IOP Publishing Ltd. All rights reserved.

关键词： Isomerization

来源：评论

学校读者我要写书评

暂无评论

Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathway

引用

生物化学与生物物理学报（英文版） 2019年第1期51卷 31-40页

作者： Tao Li Qili Li Weiguo Wu Yong Li De-xing Hou Hua Xu Baodong Zheng Shaoxiao Zeng Yang Shan Xiangyang Lu Fangming Deng Si Qin Core Research Program 1515 Key Laboratory for Food Science and Biotechnology of Hunan Province College of Food Science and Technology Hunan Agricultural University Changsha 410128 China Hunan Agricultural Product Processing Institute Hunan Academy of Agricultural Sciences Changsha 410125 China Core Research Program 1515 Key Laboratory for Food Science and Biotechnology of Hunan Province College of Food Science and Technology Hunan Agricultural University Changsha 410128 China The United Graduate School of Agricultural Sciences Faculty of Agriculture Kagoshima University Kagoshima 890-0065Japan Department of Pediatrics Steele Children's Research Center University of Arizona Tucson 85724 USA Department of Food Safety College of Food Science Fujian Agriculture and Forestry University Fuzhou 350002 China Core Research Program 1515 Key Laboratory for Food Science and Biotechnology of Hunan Province College of Food Science and Technology Hunan Agricultural University Changsha 410128 China The United Graduate School of Agricultural Sciences Faculty of Agriculture Kagoshima University Kagoshima 890-0065Japan Department of Pediatrics Steele Children's Research Center University of Arizona Tucson 85724 USA

Lotus seed is well known as traditional food and medicine,but its skin is usually *** studies have shown that lotus seed skin contains a high concentration of proanthocyanidins that have multi-functions,such as antioxidation,anti-inflammation,and anti-cancer *** the present study,we aimed to isolate and purify the proanthocyanidins from lotus seed skin by acetone extraction and rotary evaporation,identify their chemical structures by HPLC-MS-MS and NMR,and further investigate the antioxidant properties of the extract purified by macroporous resin (PMR) from lotus seed skin both in vitro and in *** results showed that PMR mainly contained oligomeric proanthocyanidins,especially dimeric procyanidin B1 (PB1),procyanidin B2 and procyanidin *** it had limited ability to directly scavenge radicals in vitro,PMR could significantly enhance the expressions of antioxidant proteins via activation of nuclear factor-E2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway in HepG2 *** data revealed that PB1,a major component in PMR,stabilized Nrf2 by inhibiting the ubiquitination of Nrf2,which led to subsequent activation of the Nrf2-ARE pathway,including the enhancements of Nrf2 nuclear translocation,Nrf2-ARE binding and ARE transcriptional ***,the in vivo results in high fat diet-induced mice further verified the powerful antioxidant property of *** results revealed that lotus seed skin is a promising resource for functional food development.

关键词： lotus seed skin extract proanthocyanidin Nrf2-ARE pathway antioxidant activity

来源：评论

学校读者我要写书评

暂无评论

Application of proteomics in identifying crucial virulence factors shared by different Streptococcus iniae isolates for developing an effective subunit vaccine against S. iniae in tilapia

引用

Aquaculture 2024年 581卷

作者： Chen, Chaio-Ping Chuang, Shu-Chun Su, Kuan-Lun Chen, Li-Kai Lin, Yi-Chen Wu, Yu-Jen Liu, Shang-Pin Hung, Shao-Wen Chen, Chung-Hwan Yang, Chung-Da Graduate Institute of Animal Vaccine Technology College of Veterinary Medicine National Pingtung University of Science and Technology Pingtung 912301 Taiwan Orthopaedic Research Center College of Medicine Kaohsiung Medical University Kaohsiung 80708 Taiwan Regenerative Medicine and Cell Therapy Research Center Kaohsiung Medical University Kaohsiung 80708 Taiwan Department of Food Science and Nutrition College of Health Science and Management Meiho University of Science and Technology Pingtung 91202 Taiwan Bachelor of Program in Scientific Agriculture College of Agriculture National Pingtung University of Science and Technology Pingtung 912301 Taiwan Division of Animal Industry Animal Technology Research Center Agricultural Technology Research Institute Hsinchu 300110 Taiwan Department of Orthopedics Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung 80701 Taiwan Departments of Orthopedics College of Medicine Kaohsiung Medical University Kaohsiung 80701 Taiwan Department of Orthopedics Kaohsiung Municipal Ta-Tung Hospital Kaohsiung 80145 Taiwan Department of Healthcare Administration and Medical Informatics Kaohsiung Medical University Kaohsiung 80701 Taiwan Institute of Medical Science and Technology National Sun Yat-sen University Kaohsiung 80424 Taiwan School of Medicine College of Medicine National Sun Yat-sen University Kaohsiung 80424 Taiwan

Streptococcus iniae (S. iniae) has become an important aquatic pathogen to cause serious streptococcosis outbreaks in cultured fish species, thus resulting in great economic losses in the worldwide aquaculture industry. Although vaccination has been so far an effective strategy to alleviate the threats of streptococcosis, antigenic variations displayed by different strains/isolates of S. iniae have brought about a severe challenge in the vaccine development. In the present study, three local S. iniae isolates, MML SI-007, MML SI-018 and MML SI-148, were first evaluated for their virulence in tilapia. Proteomics was then performed to analyze protein profiles between the highly virulent isolate (MML SI-007) and lowly virulent isolate (MML SI-018) in order to identify important virulence factors/antigens shared by different isolates. After proteomics, eleven proteins that displayed more than four times the differences in expression between MML SI-007 and MML SI-018 were identified. Two proteins, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and superoxide dismutase (SOD), were selected to be vaccine candidates for respectively cloning their genes and expressing their recombinant proteins, rGAPDH and rSOD. After peritoneal vaccination in tilapia, mixed recombinant proteins (rGAPDH + rSOD) elicited significantly higher serum titers and lymphocyte proliferation than individual recombinant proteins (rGAPDH or rSOD). In addition, maximum production of IL-6 in the head kidney was detected in fish peritoneally vaccinated with mixed recombinant proteins. More importantly, 84% (21/25) of tilapia peritoneally vaccinated with mixed recombinant proteins survived at least four weeks after a lethal peritoneal challenge of heterologous S. iniae (MML SI-148). Taken together, our results have pointed out that both GAPDH and SOD identified via proteomics are crucial virulence factors that can be protective antigens for future development of an effective cross-protective subunit vacci

关键词： Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Proteomics Streptococcus iniae (S. iniae) Superoxide dismutase (SOD) Two-dimensional gel electrophoresis (2-DE)

来源：评论

学校读者我要写书评

暂无评论

Rosa multiflora fructus and its active compound ellagic acid improve depressive-like behaviors in mice via monoamine oxidase inhibition

引用

Biomedicine and Pharmacotherapy 2025年 188卷 118169-118169页

作者： Kim, Minji Lim, Dong Wook Kim, Min-Sun Nam, Heejin Shin, Sooim Lee, Changho Um, Min Young Food Functionality Research Division Korea Food Research Institute Wanju 55365 South Korea Department of Food Biotechnology University of Science & Technology Daejeon 34113 South Korea Interdisciplinary Program of Bioenergy and Biomaterials Graduate School College of Engineering Chonnam National University Gwangju 61186 South Korea Department of Biotechnology & Bioengineering College of Engineering Chonnam National University Gwangju 61186 South Korea

Depression is a significant global health challenge, imposing severe social and economic burdens. Rosa multiflora fructus possesses a range of biological properties;however, its role in reducing stress hormone-induced depression remains unclear. This study examined the antidepressant effects of Rosa multiflora fructus extract (RMFE) on corticosterone (CORT)-induced depressive-like behaviors in mice and explored the underlying molecular mechanisms. ICR mice were administered CORT (40 mg/kg/day, i.p.) for 8 weeks to induce depressive-like behaviors. They were then treated with RMFE (100 or 300 mg/kg/day, p.o.) or selegiline (10 mg/kg/day, p.o.) as a positive control. RMFE treatment significantly alleviated depressive-like behaviors, as evaluated by the tail suspension and forced swimming tests. Furthermore, RMFE reduced hippocampal astrocyte hypertrophy and lowered the protein and mRNA expression of monoamine oxidase A and B (MAOA and MAOB). Phytochemical analysis using UPLC-MS/MS identified five flavonoids in RMFE, including ellagic acid (EA), hyperoside, isoquercetin, quercetin, and quercetin-3-glucuronide. In silico molecular docking revealed that these phenolic compounds interact with MAOA and MAOB, with EA exhibiting the strongest binding affinity. Consistently, EA administration effectively alleviated depressive-like behaviors and increased monoamine neurotransmitter levels in CORT-treated mice. These results suggest that RMFE exerts antidepressant effects by inhibiting MAO, restoring monoamine levels, and modulating hippocampal astrocytic hypertrophy, with EA identified as the primary bioactive compound driving its efficacy. © 2025

关键词： Corticosterone Depression Ellagic acid Monoamine oxidase Rosa multiflora fructus

来源：评论

学校读者我要写书评

暂无评论

A sustainable and green approach towards the utilization of biopolymers for effective wound dressing applications: A detailed review

引用

Nano-Structures and Nano-Objects 2024年 37卷

作者： Verma, Deepak Okhawilai, Manunya Nangan, Senthilkumar Thakur, Vijay Kumar Gopi, Sreeraj Kuppusamy, Kanagaraj Sharma, Mohit Uyama, Hiroshi International Graduate Program of Nanoscience and Technology Chulalongkorn University Bangkok Thailand Metallurgy and Materials Science Research Institute Chulalongkorn University Bangkok 10330 Thailand Center of Excellence in Polymeric Materials for Medical Practice Devices Department of Chemical Engineering Faculty of Engineering Chulalongkorn University Bangkok 10330 Thailand Biorefining and Advanced Materials Research Centre SRUC Kings Buildings West Mains Road Edinburgh EH9 3JG United Kingdom Centre for Research and Development Chandigarh University Punjab Mohali 140413 India Gdansk University of Technology Faculty of Chemistry Polymer Technology Department Gdansk Poland Molecule Food solutions Pvt Ltd Prestiga Atlanda Karnataka Bengaluru 560034 India Center for Supramolecular Chemistry & Catalysis and Department of Chemistry College of Science Shanghai University 99 Shang-Da Road Shanghai 200444 China Institute of Materials Research and Engineering (IMRE) Agency for Science Technology and Research (A⁎STAR) 2 Fusionopolis Way Innovis #08-03 Singapore 138634 Singapore Department of Applied Chemistry Graduate School of Engineering Osaka University Osaka 565-0871 Japan

Millions of people worldwide are suffering and struggling to obtain the most effective wound care/treatment. In previous years, a steep rise in metabolic disorders such as diabetic wound ulcers has been noticed. The primary function of an effective wound dressing is to protect the wound bed from contamination and provide an accelerated healing environment. Biopolymers, a natural boon, can be used for distinct applications from food packaging, biomedicine, and biomedical applications. Natural and synthetic biopolymers have distinct advantages, such as biocompatibility, biodegradability, and environmental friendliness. Cellulose, chitosan, alginates, hyaluronic acid, collagen, etc., are natural biopolymers primarily used to develop wound dressings. Most common synthetic biopolymers such as PVA, PCL, and PLA are examples of how an individual biopolymer or its blends can be used to develop an effective wound dressing. Biopolymer properties for wound dressing applications can be improved by applying the concepts of nanotechnology, bioengineering, and drug delivery. These improvements may help meet the current and future wound care demands for tissue repair and restoration. The current review focuses on using natural and synthetic functionalized biopolymers for effective wound-dressing applications and exhibiting their antibacterial and antimicrobial properties. © 2024 Elsevier B.V.

关键词： Biopolymer functionalization Drug delivery Natural and synthetic Biopolymers Wound dressings Wounds

来源：评论

学校读者我要写书评

暂无评论

Dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis

引用

Chemical Engineering Journal 2024年 493卷

作者： Lin, Chi Cheng, Tsai-Mu Liu, Yun-Chun Hsu, Fang-Yu Shih, Chun-Ming Tsai, Min-Lang Shih, Chun-Che Mi, Fwu-Long Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei11031 Taiwan The PhD Program for Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Taipei Heart Institute Taipei Medical University Taipei11031 Taiwan Department of Food Science National Taiwan Ocean University Keelung20224 Taiwan Department of Biochemistry and Molecular Cell Biology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Division of Cardiology and Cardiovascular Research Center Taipei Medical University Hospital Taipei11031 Taiwan Division of Cardiovascular Surgery Department of Surgery Wan Fang Hospital Taipei Medical University Taipei11031 Taiwan Institute of Clinical Medicine School of Medicine National Yang-Ming Chiao Tung University Taipei Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Graduate Institute of Nanomedicine and Medical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan International Ph.D. Program for Cell Therapy and Regeneration Medicine College of Medicine Taipei Medical University Taipei Taiwan

Limited therapeutic options are available to effectively preventing atherosclerosis. Inflammatory endothelial cells, foamy macrophages, and high protease levels contribute to atherosclerotic plaque formation. Studies have shown that catechins effectively scavenge reactive oxygen species (ROS), inhibit monocyte adhesion and reduce cholesterol levels, while nitric oxide (NO) enhances endothelial function. However, due to the poor stability and bioavailability of catechins and the toxicity from the burst release of current synthetic small molecules NO donor, effective delivery of these bioactive compounds to treat atherosclerosis is still a challenge. Herein, a catechin/protein-based NO donor co-delivery nanosystem was designed for combinatorial anti-atherosclerotic therapy. We engineered a (−)-epigallocatechin-3-gallate (EGCG)/NO-releasing protein co-assembled nanocomplex based on specific catechin-protein interactions. Furthermore, the nanocomplex was surface modified with fucoidan (Fu), a sulfated polysaccharide with anti-inflammatory activity. This nanocomplex exhibits sensitivity to ROS, pH, and enzymes. The Fu-functionalized nanoparticles specifically accumulates in atherosclerotic plaques mediated by P-selectin on inflamed endothelial cells and scavenger receptor A (SR-A) on foamy macrophages. Under environmental stimuli that simulate the condition of plaque, the nanoparticles are readily activated to release EGCG and NO in response to excess ROS and high protease levels, exerting the multi-synergistic anti-atherosclerosic effects on reducing monocyte adhesion, promoting NO production to proliferate endothelial cells, lowering ROS levels, and decreasing the foam cell formation in vitro, and reducing lipid accumulation, plaque size, and inflammatory cytokines release in high-fat diet-induced atherosclerosis model in ApoE−/− mice. The integration of plaques targeting ability and multiple therapeutic functions can provide an advanced therapeutic strategy for athero

关键词： Nitric oxide

来源：评论

学校读者我要写书评

暂无评论

Correction: Influence of the ecological environment on the structural characteristics and bioactivities of polysaccharides from alfalfa (Medicago sativa L.)

引用

food & function 2022年第14期13卷 7942-7943页

作者： Chongyu Zhang Eunyoung Kim Jiamei Cui Yunpeng Wang Yunkyoung Lee Guiguo Zhang Department of Nutrition and China-Korea Joint R&D center on Plant-derived polysaccharide Shandong Agricultural University 61 Daizong Street Taian City 271018 China. zhanggg@***. Department of Food Science and Nutrition and Korea-China Joint R&D center on Plant-derived polysaccharide Jeju National University Jeju 63243 South Korea. lyk1230@jejunu.ac.kr. Interdisciplinary Graduate Program in Advanced Convergence Technology & Science Jeju National University Jeju 63243 South Korea.

Correction for 'Influence of the ecological environment on the structural characteristics and bioactivities of polysaccharides from alfalfa ( L.)' by Chongyu Zhang , , 2022, https://***/10.1039/d2fo00371f.

关键词：

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：