Robot based therapy is one of the prevalent therapeutic approaches in motor stroke rehabilitation. It is often used in hospitals in combination with conventional therapy. In order to optimize human-robot interaction, ...
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In order to ensure a sustainable supply of the population with affordable medicines, it is necessary to organize pharmaceutical production processes efficiently in terms of costs, process quality, time and flexibility...
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In order to ensure a sustainable supply of the population with affordable medicines, it is necessary to organize pharmaceutical production processes efficiently in terms of costs, process quality, time and flexibility. Lean productionsystems (LPS) have proved as an effective way to respond appropriately to these requirements. To date, the transfer of established models to the pharmaceutical industry and especially small and medium-sized enterprises (SMEs) is difficult, because of special characteristics regarding production processes and regulatory requirements. At the same time, SMEs often lack the necessary knowledge to develop suitable LPS themselves. The paper describes Lean success factors and barriers and proposes an LPS implementation process taking into account the unique features of SMEs in the pharmaceutical industry. Special attention is given to the consideration of human-oriented factors and the appropriate selection of Lean methods, which are aligned with business goals.
The appearance of Industrie 4.0 also known as cyber-physical systems and internet of things enables a continuous creation of data based on intelligent facilities. It is assumed that data will be one of the main resour...
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This volume provides a concise reference to the state-of-the-art in software interoperability. Composed of over 90 papers, Enterprise Interoperability II ranges from academic research through case studies to industria...
ISBN:
(纸本)9781447171317
This volume provides a concise reference to the state-of-the-art in software interoperability. Composed of over 90 papers, Enterprise Interoperability II ranges from academic research through case studies to industrial and administrative experience of interoperability. The international nature of the authorship continues to broaden. Many of the papers have examples and illustrations calculated to deepen understanding and generate new ideas.
Every surface exposed in the oral cavity is covered by a layer of salivary proteins (pellicle). The initial formation of the pellicle, which is a cellular, proteinaceous film on the surface, is followed by the adsorpt...
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Every surface exposed in the oral cavity is covered by a layer of salivary proteins (pellicle). The initial formation of the pellicle, which is a cellular, proteinaceous film on the surface, is followed by the adsorption of bacterial cells. Well-developed biofilms on dental implant surfaces become the main source of pathogenic microbes causing Peri-Implantitis, a condition that has been described as one of the main causes of dental implant failure. The surface wettability affects the formation of pellicle and biofilms. This paper presents laser surface microtexturing as a surface treatment of Ti-6Al-4V against the settlement of the bacteria Streptococcus mutans .
Current industrial development is faced by the global challenge to meet the continuously growing demand for capital and consumer goods in emerging countries while simultaneously ensuring a sustainable industrial growt...
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Laser-Metal-Deposition (LMD) and Plasma-Transferred-Arc (PTA) are well known technologies which can be used for cladding purposes. The prime objective in combining LMD and PTA as a Hybrid Metal Deposition-technology (...
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Laser-Metal-Deposition (LMD) and Plasma-Transferred-Arc (PTA) are well known technologies which can be used for cladding purposes. The prime objective in combining LMD and PTA as a Hybrid Metal Deposition-technology (HMD) is to achieve high deposition rates at low thermal impact. Possible applications are coatings for wear protection or repair welding for components made of steel. The two energy sources (laser and plasma arc) build a joint process zone and are configurated to constitute a stable process at laser powers between 0.4-1 kW (defocused) and plasma currents between 75-200 A. Stainless steel 316L serves as filler material. For this HMD process, a plasma Cu-nozzle is designed and produced by powder bed based Selective Laser Melting. The potential of the HMD technology is investigated and discussed considering existing processes. This paper demonstrates how the interaction of the two energy sources effects the following application-relevant properties: deposition rate, powder efficiency and energy input.
The paper deals with the integration of a light emitting diode (LED) into an additive manufactured metal component. Selective laser melting (SLM) and laser metal deposition (LMD) are used. The material used is the chr...
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The paper deals with the integration of a light emitting diode (LED) into an additive manufactured metal component. Selective laser melting (SLM) and laser metal deposition (LMD) are used. The material used is the chrome-nickel steel 316L. The basic component is manufactured by means of SLM and consists of a solid body and an area with grid structure. The solid body includes a duct in the shape of a groove with a recess for the positioning of the power cable. The LED is embedded in the grid structure via an inlet from the solid body. In further processing, the groove is filled with LMD. Two strategies with different parameter combinations were investigated. It shows that a high energy input near the power cable leads to its destruction. By using multiple parameter combinations during the manufacturing process, this destruction can be prevented. There was a comparison of both strategies with regard to the necessary number of tracks and duration of welding time.
The presented work is an alternative to established measurement systems in surgical navigation. The system is based on camera based tracking of QR code markers. The application uses a single video camera, integrated i...
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Selective Laser Melting is an additive manufacturing process, in which the research has been increasing over the past few years to meet customer-specific requirements. Therefore, new manufacturing parameters have been...
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Selective Laser Melting is an additive manufacturing process, in which the research has been increasing over the past few years to meet customer-specific requirements. Therefore, new manufacturing parameters have been monitored raising the number of sensors in the machines. Consequently, it leads to a bigger amount of data and difficulties to perform manual data analysis. In order to improve the analysis, this paper illustrates a possibility of pattern recognition using a different historical process and sensors data from a SLM machine. The results are evaluated using an intelligent tool for algorithms configuration and data analysis developed at fraunhoferipk.
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