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Control Logic Routing for Continuous-Flow Microfluidic Biochips Based on Deep Reinforcement Learning

Jisuanji Yanjiu yu Fazhan/Computer Research and Development 2025年第4期62卷 950-962页

作者： Cai, Huayang Huang, Xing Liu, Genggeng College of Computer and Data Science Fuzhou University Fuzhou350116 China Engineering Research Center of Big Data Intelligence Fuzhou University Ministry of Education Fuzhou350116 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350116 China School of Computer Science Northwestern Polytechnical University Xi’an710072 China

With the advancement of electronic design automation, continuous-flow microfluidic biochips have become one of the most promising platforms for biochemical experiments. This chip manipulates fluid samples in milliliters or nanoliters by utilizing internal microvalves and microchannels, and thus automatically performs basic biochemical experiments, such as mixing and detection. To achieve the correct bioassay function, the microvalves deployed inside the chip are usually managed by a multiplexer-based control logic, and valves receive control signals from a core input through the control channel for accurate switching. Since biochemical reactions typically require high sensitivity, the length of control paths connecting each valve needs to be reduced to ensure immediate signal propagation, and thus to reduce the signal propagation delay. In addition, to reduce the fabrication cost of chips, a vital issue to be addressed in the logic architecture design is how to effectively reduce the total channel length within the control logic. To address the above issues, we propose a deep reinforcement learning-based control logic routing algorithm to minimize the signal propagation delay and total control channel length, thereby automatically constructing an efficient control channel network. The algorithm employs the dueling deep Q-network architecture as the agent of the deep reinforcement learning framework to evaluate the tradeoff between signal propagation delay and total channel length. Besides, the diagonal channel routing is implemented for the first time for control logic, thus fundamentally improving the efficiency of valve switching operations and reducing the fabrication cost of the chip. The experimental results demonstrate that the proposed algorithm can effectively construct a high-performance and low-cost control logic architecture. © 2025 Science Press. All rights reserved.

关键词： Deep reinforcement learning

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Communication-Efficient Personalized Distributed Learning with Data and Node Heterogeneity

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IEEE Transactions on Cognitive Communications and networking 2025年

作者： Tian, Zhuojun Zhang, Zhaoyang Li, Yiwei Bennis, Mehdi Zhejiang University College of Information Science and Electronic Engineering Hangzhou310027 China University of Oulu Center for Wireless Communications Oulu90014 Finland State Key Laboratory of Industrial Control Technology Hangzhou310027 China Zhejiang Provincial Key Laboratory of Multimodal Communication Networks and Intelligent Information Processing Hangzhou310027 China Xiamen University of Technology Fujian Key Laboratory of Communication Network and Information Processing Xiamen361024 China

To jointly tackle the challenges of data and node heterogeneity in decentralized learning, we propose a distributed strong lottery ticket hypothesis (DSLTH), based on which a communication-efficient personalized learning algorithm is developed. In the proposed method, each local model is represented as the ‌Hadamard product of global real-valued parameters and a personalized binary mask for pruning. The local model is learned by updating and fusing the personalized binary masks while the real-valued parameters are fixed among different agents. To further reduce the complexity of hardware implementation, we incorporate a group sparse regularization term in the loss function, enabling the learned local model to achieve structured sparsity. Then, a binary mask aggregation algorithm is designed by introducing an intermediate aggregation tensor and adding a personalized fine-tuning step in each iteration, which constrains model updates towards the local data distribution. The proposed method effectively leverages the relativity among agents while meeting personalized requirements in heterogeneous node conditions. We also provide a theoretical proof for the DSLTH, establishing it as the foundation of the proposed method. Numerical simulations confirm the validity of the DSLTH and demonstrate the effectiveness of the proposed algorithm. © 2015 IEEE.

关键词： Iterative methods

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MEFA-Net: A mask enhanced feature aggregation network for polyp segmentation

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Computers in Biology and Medicine 2025年 186卷 109601-109601页

作者： Ke, Xiao Chen, Guanhong Liu, Hao Guo, Wenzhong Fujian Provincial Key Laboratory of Networking Computing and Intelligent Information Processing College of Computer and Data Science Fuzhou University Fuzhou350116 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350116 China

Accurate polyp segmentation is crucial for early diagnosis and treatment of colorectal cancer. This is a challenging task for three main reasons: (i) the problem of model overfitting and weak generalization due to the multi-center distribution of data;(ii) the problem of interclass ambiguity caused by motion blur and overexposure to endoscopic light;and (iii) the problem of intraclass inconsistency caused by the variety of morphologies and sizes of the same type of polyps. To address these challenges, we propose a new high-precision polyp segmentation framework, MEFA-Net, which consists of three modules, including the plug-and-play Mask Enhancement Module (MEG), Separable Path Attention Enhancement Module (SPAE), and Dynamic Global Attention Pool Module (DGAP). Specifically, firstly, the MEG module regionally masks the high-energy regions of the environment and polyps through a mask, which guides the model to rely on only a small amount of information to distinguish between polyps and background features, avoiding the model from overfitting the environmental information, and improving the robustness of the model. At the same time, this module can effectively counteract the "dark corner phenomenon" in the dataset and further improve the generalization performance of the model. Next, the SPAE module can effectively alleviate the inter-class fuzzy problem by strengthening the feature expression. Then, the DGAP module solves the intra-class inconsistency problem by extracting the invariance of scale, shape and position. Finally, we propose a new evaluation metric, MultiColoScore, for comprehensively evaluating the segmentation performance of the model on five datasets with different domains. We evaluated the new method quantitatively and qualitatively on five datasets using four metrics. Experimental results show that MEFA-Net significantly improves the accuracy of polyp segmentation and outperforms current state-of-the-art algorithms. Code posted on https://***/

关键词： Endoscopy

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Virtualizing Next-Generation Programmable networks: Techniques, Use Cases, and Promising Future Directions

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IEEE network 2025年第3期39卷 148-155页

作者： Chen, Xiang Du, Hongyang Liu, Wenjing Liu, Hongyan Zhang, Jianshan Yang, Xu Zhang, Dong Wu, Chunming Liu, Xuan Niyato, Dusit Zhejiang University College of Computer Science and Technology Hangzhou310027 China The University of Hong Kong Department of Electrical and Electronic Engineering Pokfulam Hong Kong Zhejiang Media Group Hangzhou310005 China Minjiang University Fujian Provincial Key Laboratory of Information Processing and Intelligent Control College of Computer and Data Science Fuzhou350108 China Fuzhou University College of Computer and Data Science Fuzhou350108 China Yangzhou University College of Information Engineering College of Artificial Intelligence Yangzhou225009 China Nanyang Technological University College of Computing and Data Science Jurong West 639798 Singapore

For decades, network virtualization plays a crucial role in modern networks, e.g., 6G mobile networks: tenants construct arbitrary virtual networks on the same physical network. However, production networks are becoming programmable and need more ways of network configurations. So prior techniques like SDN hypervisors are deprecated since they cannot configure programmable networks. In response, a new category of network virtualization techniques has emerged recently to virtualize programmable networks, i.e., programmable network hypervisors (PNHs). This article first reviews this trend to comprehensively survey PNHs. To understand their benefits, we build a testbed with hardware switches and sophisticated topologies. Our testbed experiments stress-test hypervisors and demonstrate that they outperform prior works with higher acceptance ratios of virtual networks under large-scale scenarios and heavy loads. Finally, we highlight the open issues of these techniques to shed light on the future directions in this promising topic. © 1986-2012 IEEE.

关键词： Virtualization

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D-FGNAE: Decentralized Federated Graph Normalized AutoEncoder 19th

D-FGNAE: Decentralized Federated Graph Normalized AutoEncode...

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19th CCF Conference on Computer Supported Cooperative Work and Social computing, ChineseCSCW 2024

作者： Liang, Yuting Cai, Weixin Guo, Kun College of Computer and Data Science Fuzhou University Fuzhou350108 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350108 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350108 China

ISBN: (纸本)9789819623723

Graphs widely exist in real-world, and Graph Neural networks (GNNs) have exhibited exceptional efficacy in graph learning in diverse fields. With the strengthening of data privacy protection worldwide in recent years, Federated graph neural networks (FedGNNs) have gained increasing attention in academia and industry owing to their ability to train the model in a collaborative manner while complying with the privacy protection regulations. However, in federated learning, the non-independent and identically distributed (non-IID) problem of local data possessed by multiple participants can significantly undermine model accuracy. We propose a new Decentralized Federated Graph Normalized AutoEncoder (D-FGNAE). First, the model is designed as a decentralized federated learning framework with dynamically assigned tripartite roles. This design eliminates the fixed server role found in traditional federated learning, enhances system fault tolerance, avoids single points of failure, and protects model privacy. Second, the splitting and correcting of calculation by layer in the model, along with the special design of the normalization layer, effectively tackle the non-IID problem in both the structural and attribute aspects. Experimental results on real-world networks demonstrate the effectiveness of D-FGNAE, which can achieve nearly the same accuracy as the centralized model. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Federated learning

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Community-Aware Heterogeneous Graph Contrastive Learning 19th

Community-Aware Heterogeneous Graph Contrastive Learning

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19th CCF Conference on Computer Supported Cooperative Work and Social computing, ChineseCSCW 2024

作者： Li, Xinying Wu, Ling Guo, Kun College of Computer and Data Science Fuzhou University Fuzhou350108 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350108 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350108 China

ISBN: (纸本)9789819623723

Recently, heterogeneous graph contrastive learning, which can mine supervision signals from the data, has attracted widespread attention. However, most existing methods employ random data augmentation strategies to construct contrastive views, which may destroy the semantic information in heterogeneous graphs. Moreover, they often select positive and negative samples based solely on node-level proximity and overlook hard samples that are difficult to distinguish from anchors. To solve the above problems, we propose a Community-Aware Heterogeneous Graph Contrastive Learning model called CAHGCL. In particular, we design an adaptive data augmentation strategy to construct views, including feature augmentation and topology augmentation. To improve the quality of samples, we propose a dynamic sample weighting strategy based on node similarity and community information, capable of identifying both hard positive samples and hard negative samples. Finally, we introduce community-level contrast to improve community cohesion. Extensive experiments and analyses demonstrate that CAHGCL consistently outperforms state-of-the-art baselines on three datasets. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Contrastive Learning

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UGCM-LU: A Unified Stream and Batch Graph computing Model with Local Update for Community Detection 19th

UGCM-LU: A Unified Stream and Batch Graph Computing Model w...

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19th CCF Conference on Computer Supported Cooperative Work and Social computing, ChineseCSCW 2024

作者： Li, Hong Wu, Ling Guo, Kun College of Computer and Data Science Fuzhou University Fuzhou350108 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350108 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350108 China

ISBN: (纸本)9789819623723

Unified stream and batch computing (USBC) aims to incorporate stream and batch computation into a unified framework, thereby enabling the development of a one-stop solution for stream and batch data processing and enhancing the generalization of the framework. However, research on unified graph computing models (UGCMs) faces several challenges. First, existing UGCMs need to consider all graph information in the cache during the incremental update phase, thus leading to decreased execution efficiency. Second, existing UGCMs use fixed bytes to store nodes without considering the actual space occupied by nodes resulting in wasted memory when dealing with large graphs. This paper proposes a UGCM with Local Updates for community detection (UGCM-LU). We first implement a local update strategy to consider partial information of the graph to achieve incremental updates. Secondly, we also designed a byte-compression-based module to store graph data according to the space occupied by nodes. The experimental results show the effectiveness and efficiency of the model in real-world and artificial networks. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Lutetium alloys

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Community Evolution Tracking Based on High-Order Neighbor Consideration and Node Change Identification 19th

Community Evolution Tracking Based on High-Order Neighbor C...

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19th CCF Conference on Computer Supported Cooperative Work and Social computing, ChineseCSCW 2024

作者： Zhang, Yunan Wang, Chaohui Wu, Ling Guo, Kun College of Computer and Data Science Fuzhou University Fuzhou350108 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350108 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350108 China

ISBN: (纸本)9789819623723

Community evolution tracking is widely used in complex network analysis, which analyzes and identifies how communities evolve over time based on dynamic community detection. However, the current incremental dynamic community detection method has the phenomenon of ’concept drift’, which leads to inaccurate tracking of community evolution. Although some studies on dynamic community detection have proposed to perform global community detection on the network by timing or when the error information accumulates to a certain extent, this method will lead to a sudden change in community division, which will interrupt the evolution sequence of some communities and bring great difficulties to the continuous tracking of community evolution. In addition, the current community evolution tracking methods match the communities of two adjacent snapshots, and it is difficult to capture the fine-grained evolution process within the community. This paper proposes a community evolution tracking algorithm based on high-order neighbor consideration and node change identification. Firstly, based on an incremental update strategy that considers high-order neighbors, we adaptively expand the scope of incremental updates to reduce the accumulation of error information. Secondly, through the node change identification strategy to mine fine-grained community evolution events. Experiments show that our method can effectively track the evolution of communities in dynamic networks. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Community evolution Complex network Dynamic network Evolution tracking

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On the -differential spectra of two classes of power functions over finite fields

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Applicable Algebra in Engineering, Communication and computing 2025年 1-30页

作者： Liu, Qian Huang, Zhiwei Chen, Zhixiong Jiang, Rong Zhang, Liupiao Key Laboratory of Information Security of Network Systems College of Computer and Data Science Fuzhou University Fuzhou China Hubei Key Laboratory of Applied Mathematics Faculty of Mathematics and Statistics Hubei University Wuhan China Yunnan Key Laboratory of Service Computing Yunnan University of Finance and Economics Kunming China Fujian Key Laboratory of Financial Information Processing Putian University Putian China School of Computer Science and Technology Dongguan University of Technology Dongguan China

Recently, a new concept called multiplicative differential was introduced by Ellingsen et al. [7]. As an extension of the differential uniformity, it is theoretically appealing to determine the properties of c-differential uniformity and the corresponding c-differential spectrum. In this paper, based on certain quadratic character sums and two special elliptic curves over $$\mathbb {F}_p$$ , the $$(-1)$$ -differential spectra of the following two classes of power functions over $$\mathbb {F}_{p^n}$$ is completely determined: (1) $$f_1(x)=x^{\frac{p^n+3}{2}}$$ , where $$p>3$$ and $$p\equiv 3\pmod 4$$ ; (2) $$f_2(x)=x^{p^n-3}$$ , where $$p>3$$ . The obtained result shows that the $$(-1)$$ -differential spectra of $$f_1(x)$$ and $$f_2(x)$$ can be expressed explicitly in terms of n. Moreover, an upper bound of the c-differential uniformity of $$f_2(x)$$ is given.

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High-precision end-to-end adaptive optics aided orbital angular momentum wireless communication with XFTC-Net

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Optics Letters 2025年第10期50卷 3265-3268页

作者： Panpan Xu Huan Chang Fei Wang Ran Gao Dong Guo Lei Zhu Zhipei Li Sitong Zhou Qi Xu Jing Chen Xiangjun Xin School of Information and Electronics Beijing Institute of Technology (BIT) Beijing 100081 China National Key Laboratory of Science and Technology on Space-Born Intelligent Information Processing Beijing China School of Electronic Engineering Beijing University of Posts and Telecommunications (BUPT) Beijing 100876 China Key Laboratory of Computing Power Network and Information Security Ministry of Education Qilu University of Technology 250353 China

In this Letter, we demonstrate high-precision end-to-end adaptive optics (AO) technique based on the X-Shape Fusion Transformer-convolutional neural network (XFTC-Net) without an additional probe path to compensate for distortions caused by atmospheric turbulence (AT) in orbital angular momentum (OAM) optical wireless communication links. The experimental results show that the XFTC-Net effectively extracts the intensity distribution features of distorted OAM beams, predicting AT phase screens and identifying OAM modes. After XFTC-Net-aided AO compensation, the bit error rate of the OAM optical communication system remains below 3.8 × 10 −3 , staying within $C_{n}^2=1 \times 10^{-15}$ –1 × 10 −13 m −2/3 . Moreover, the optical power with l = 3 increases from 5.08 dBm to 8.23 dBm at a transmission distance of 800 m. These experimental results indicate that the proposed XFTC-Net AO technique effectively compensates for OAM beam distortion in both single- and multiplexed-channel OAM links, which effectively balances the system complexity and transmission performance of OAM-based free space optical (FSO) communication systems, opening up new avenues for enhancing the performances of high-capacity optical communication.

关键词： Adaptive optics Bit error rate Neural networks Optical wireless communication Polarization division multiplexing Space division multiplexing

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