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检索条件"机构=Genetics PhD Program"
53 条 记 录,以下是1-10 订阅
排序:
Identification of sex-biased MiRNA markers informative of heat-past events
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BMC Genomics 2025年 第1期26卷 1-17页
作者: van Gelderen, Tosca A. Montfort, Jerome Álvarez-Dios, José Antonio Piferrer, Francesc Bobe, Julien Ribas, Laia Institut de Ciències del Mar Consejo Superior de Investigaciones Científicas (ICM-CSIC) Barcelona 08003 Spain PhD Program in Genetics Autonomous University of Barcelona Bellaterra 08193 Spain INRAE Laboratoire de Physiologie et Génomique des Poissons Rennes France Departamento de Matemática Aplicada Facultad de Matemáticas Universidad de Santiago de Compostela Santiago de Compostela 15781 Spain
Elevated temperatures during early developmental stages play a pivotal role in the fate of the adult sexual phenotype of fish populations, usually leading to male-skewed sex ratios. This is the case with European sea ... 详细信息
来源: 评论
Genomic data processing with GenomeFlow
arXiv
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arXiv 2025年
作者: Park, Junseok Maury, Eduardo A. Oh, Changhoon Shin, Donghoon Denisko, Danielle Lee, Eunjung Alice Division of Genetics and Genomics Boston Children’s Hospital 3 Blackfan Circle BostonMA United States Department of Pediatrics Harvard Medical School 25 Shattuck St BostonMA United States Bioinformatics Integrative Genomics Program Harvard/MIT MD-PHD Program Harvard Medical School BostonMA United States Program in Medical and Population Genetics Broad Institute of MIT and Harvard CambridgeMA United States Graduate School of Information Yonsei University 50 Yonsei-ro Seodaemun-gu Seoul Korea Republic of Department of Human Centered Design and Engineering University of Washington SeattleWA United States Department of Biomedical Informatics Harvard Medical School BostonMA United States
Advances in genome sequencing technologies generate massive amounts of sequence data that are increasingly analyzed and shared through public repositories. On-demand infrastructure services on cloud computing platform... 详细信息
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CIWARS: A Web Server for Antibiotic Resistance Surveillance Using Longitudinal Metagenomic Data
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Journal of Molecular Biology 2025年
作者: Emon, Muhit Islam Cheung, Yat Fei Stoll, James Rumi, Monjura Afrin Brown, Connor Choi, Joung Min Moumi, Nazifa Ahmed Ahmed, Shafayat Song, Haoqiu Sein, Justin Yao, Shunyu Khan, Ahmad Gupta, Suraj Kulkarni, Rutwik Butt, Ali Vikesland, Peter Pruden, Amy Zhang, Liqing Department of Computer Science Virginia Tech Blacksburg 24060 VA United States Fralin Life Science Institute Virginia Tech Blacksburg 24060 VA United States Department of Civil and Environmental Engineering Virginia Tech Blacksburg 24060 VA United States The Interdisciplinary PhD Program in Genetics Bioinformatics and Computational Biology Virginia Tech Blacksburg 24060 VA United States
The rise of antibiotic resistance (AR) poses a substantial threat to human and animal health, food security, and economic stability. Wastewater-based surveillance (WBS) has emerged as a powerful strategy for populatio... 详细信息
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TRIM52 maintains cellular fitness and is under tight proteolytic control by multiple giant E3 ligases
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Nature Communications 2025年 第1期16卷 1-19页
作者: Shulkina, Alexandra Hacker, Kathrin Ehrmann, Julian F. Budroni, Valentina Mandlbauer, Ariane Bock, Johannes Grabarczyk, Daniel B. Edobor, Genevieve Cochella, Luisa Clausen, Tim Versteeg, Gijs A. Max Perutz Labs Vienna Biocenter Campus (VBC) Dr.-Bohr-Gasse 9 Vienna 1030 Austria University of Vienna Center for Molecular Biology Department of Microbiology Immunobiology and Genetics Dr.-Bohr-Gasse 9 Vienna 1030 Austria Vienna Biocenter PhD Program a Doctoral School of the University of Vienna and the Medical University of Vienna Vienna 1030 Austria Research Institute of Molecular Pathology (IMP) Vienna BioCenter (VBC) Vienna Austria Department of Molecular Biology and Genetics Johns Hopkins School of Medicine Baltimore 21205 MD United States Medical University of Vienna Vienna BioCenter (VBC) Vienna Austria Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Boston 02115 MA United States Program in Cellular and Molecular Medicine Boston Children’s Hospital Boston 02115 MA United States
Tripartite motif 52 (TRIM52) exhibits strong positive selection in humans, yet is lost in many other mammals. In contrast to what one would expect for such a non-conserved factor, TRIM52 loss compromises cell fitness....
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Multi-site investigation of gut microbiota in CDKL5 deficiency disorder mouse models: Targeting dysbiosis to improve neurological outcomes
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Cell Reports 2025年 第4期44卷 115546页
作者: Damiani, Francesca Giuliano, Maria Grazia Cornuti, Sara Putignano, Elena Tognozzi, Andrea Suckow, Vanessa Kalscheuer, Vera M. Pizzorusso, Tommaso Tognini, Paola Laboratory of Biology BIO@SNS Scuola Normale Superiore Piazza dei Cavalieri 7 Pisa 56126 Italy Health Science Interdisciplinary Center Sant'Anna School of Advanced Studies Piazza Martiri della Libertà 33 Pisa 56127 Italy Institute of Neuroscience National Research Council Via G. Moruzzi 1 Pisa 56124 Italy PhD Program in Clinical and Translational Science University of Pisa Via Savi 10 Pisa 56126 Italy Max Planck Institute for Molecular Genetics Ihnestraße 63 Berlin 14195 Germany
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare neurodevelopmental disorder often associated with gastrointestinal (GI) issues and subclinical immune dysregulation, suggesting a link to the ... 详细信息
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Fate and state transitions during human blood vessel organoid development
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Cell 2025年
作者: Nikolova, Marina T. He, Zhisong Seimiya, Makiko Jonsson, Gustav Cao, Wuji Okuda, Ryo Wimmer, Reiner A. Okamoto, Ryoko Penninger, Josef M. Camp, J. Gray Treutlein, Barbara Department of Biosystems Science and Engineering ETH Zurich Basel Switzerland Institute of Molecular Biotechnology of the Austrian Academy of Sciences Vienna Austria Vienna BioCenter PhD Program Doctoral School of the University of Vienna and Medical University of Vienna Vienna 1030 Austria Roche Pharma Research and Early Development Roche Innovation Center Basel Switzerland Department of Medical Genetics Life Science Institute University of British Columbia Vancouver V6T 1Z3 BC Canada Department of Laboratory Medicine Medical University of Vienna Vienna Austria Helmholtz Centre for Infection Research Braunschweig Germany Institute of Human Biology Roche Pharma Research and Early Development Roche Innovation Center Basel Basel Switzerland Biozentrum University of Basel Basel Switzerland
Human blood vessel organoids (hBVOs) have emerged as a system to model human vascular development and disease. Here, we use single-cell multi-omics together with genetic and signaling pathway perturbations to reconstr... 详细信息
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Discovering nanoparticle corona ligands for liver macrophage capture
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Nature Nanotechnology 2025年 1-12页
作者: Bram Bussin Marshall G. G. MacDuff Sara Ahmed Wayne Ngo Jamie L. Y. Wu Zachary P. Lin Benjamin Stordy Zahra Sepahi Jason Moffat Warren C. W. Chan Adrian Granda Farias Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada Institute of Biomedical Engineering University of Toronto Toronto Ontario Canada Terrence Donnelly Centre for Cellular and Biomolecular Research University of Toronto Toronto Ontario Canada Department of Molecular Genetics University of Toronto Toronto Ontario Canada MD/PhD Program University of Toronto Toronto Ontario Canada Gladstone Institutes San Francisco CA USA California Institute for Quantitative Biosciences University of California Berkeley Berkeley CA USA Innovative Genomics Institute University of California Berkeley Berkeley CA USA Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario Canada School of Chemistry Chemical Engineering and Biotechnology Nanyang Technological University Singapore Singapore
Liver macrophages capture circulating nanoparticles and reduce their delivery to target organs. Serum proteins adsorb to the nanoparticle surface after administration. However, the adsorbed serum proteins and their co...
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TNF MicrosatelUtes in patients with systemic lupus erythemathosus
TNF MicrosatelUtes in patients with systemic lupus erythemat...
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The 8th International Congress on SLE
作者: Oliveira C.B. Rassi D.M. Wastowski I.J. Sim■es A.L Mendes-Junior C.T. Donadi E.A. (MSc) Program of Basic and Applied Immunology (PhD) Division of Clinical Immunology of the Department of Medicine (MSc) Program of Basic and Applied Immunology (MD PhD) Department of Genetics-Faculty of Medicine of Ribeino Preto University of So Paulo Brazil (PhD) Division of Clinical Immunology of the Department of Medicine (MD PhD) Program of Basic and Applied Immunology Division of Clinical Immunology of the Department of Medicine
Introduction:Systemic lupus erythemathosus(SLE)is a chronic inflammatory autoimmune disease of unknown etiology,characterized by autoantibody production that affects multiple organs and ***, immunological,genetic and ... 详细信息
来源: 评论
Surgical menopause enhances hippocampal amyloidogenesis following global cerebral ischemia
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Journal of Sport and Health Science 2014年 第3期3卷 206-216页
作者: Erin L.Scott Quan-Guang Zhang Yan Dong Dong Han Rui-Min Wang Ratna K.Vadlamudi Darrell W.Brann University System of Georgia MD/PhD Program Georgia Regents University Institute of Molecular Medicine and Genetics.Georgia Regents University Department of Obstetrics and Gynecology.University of Texas Health Science Center at San Antonio
Background: Prematurely menopausal women have a doubled lifetime risk of dementia and a 5-fold increased risk of mortality from neuro- logical disorders, but the molecular mechanisms underlying these risks remain unc... 详细信息
来源: 评论
Targeting multiple signaling pathways:the new approach to acute myeloid leukemia therapy
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Signal Transduction and Targeted Therapy 2021年 第1期6卷 41-69页
作者: Jenna LCarter Katie Hege Jay Yang Hasini AKalpage Yongwei Su Holly Edwards Maik Hüttemann Jeffrey WTaub Yubin Ge Cancer Biology Graduate Program Wayne State University School of MedicineDetroitMIUSA MD/PhD Program Wayne State University School of MedicineDetroitMIUSA Department of Oncology Wayne State University School of MedicineDetroitMIUSA Molecular Therapeutics Program Barbara Ann Karmanos Cancer InstituteWayne State University School of MedicineDetroitMIUSA Center for Molecular Medicine and Genetics Wayne State University School of MedicineDetroitMIUSA National Engineering Laboratory for AIDS Vaccine Key Laboratory for Molecular Enzymology and EngineeringThe Ministry of EducationSchool of Life SciencesJilin UniversityChangchunChina Division of Pediatric Hematology/Oncology Children’s Hospital of MichiganDetroitMIUSA Department of Pediatrics Wayne State University School of MedicineDetroitMIUSA
Acute myeloid leukemia(AML)is the most common form of acute leukemia in adults and the second most common form of acute leukemia in *** this,very little improvement in survival rates has been achieved over the past fe... 详细信息
来源: 评论