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Proceedings of the 16th Annual UT-KBRIN Bioinformatics Summit 2016: bioinformatics

BMC Bioinformatics 2017年第9期18卷 1-9页

作者： Eric C. Rouchka Juw Won Park Julia H. Chariker David A. Tieri Shreedharkumar Rajurkar Vikas Singh Nishchal K. Verma Yan Cui Mark Farman Bradford Condon Jolanta Jaromczyk Neil Moore Jerzy Jaromczyk Daniel Harris Patrick Calie Eun Kyong Shin Robert L. Davis Arash Shaban-Nejad Joshua M. Mitchell Hunter N. B. Moseley Robert M. Flight Qing Jun Wang Richard M. Higashi Teresa W-M Fan Andrew N. Lane Liangqun Lu Bernie J Daigle Jr. Xi Chen Andrey Smelter Jerzy W. Jaromczyk Bailey K. Phan Nathaniel J. Serpico Ethan G. Toney Li Chen Caroline E. Melton Jennifer R. Mandel Bernie J. Daigle Jr. Hao Chen Kazi I. Zaman Ramin Homayouni Patrick J. Trainor Andrew P. DeFilippis Samantha M. Carlisle Shesh N. Rai Department of Computer Engineering and Computer Science University of Louisville Duthie Center for Engineering Louisville KY 40292 USA Kentucky Biomedical Research Infrastructure (KBRIN) Bioinformatics Core 522 East Gray Street Louisville KY 40292 USA Department of Psychological and Brain Sciences University of Louisville Louisville KY 40292 USA Department of Anatomical Sciences and Neurobiology University of Louisville Louisville KY 40292 USA Department of Electrical Engineering IIT Kanpur India Department of Microbiology Immunology and Biochemistry University of Tennessee Health Science Center Memphis TN 38103 USA Center for Integrative and Translational Genomics University of Tennessee Health Science Center Memphis TN 38103 USA Department of Plant Pathology University of Kentucky Lexington KY 40546 USA UK Healthcare Genomics University of Kentucky Lexington KY 40536 USA Department of Entomology & Plant Pathology University of Tennessee Knoxville TN 37996 USA Department of Forestry University of Kentucky Lexington KY 40506 USA Department of Computer Science University of Kentucky Lexington KY 40506 USA Department of Computer Science University of Kentucky Lexington KY 40508 USA Department of Biological Sciences Eastern Kentucky University Richmond KY 40475 USA University of Tennessee Health Science Center – Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics Department of Pediatrics Memphis TN 38103 USA Department of Molecular & Cellular Biochemistry University of Kentucky Lexington KY 40536 USA Markey Cancer Center University of Kentucky Lexington KY 40536 USA Center for Environmental and Systems Biochemistry University of Kentucky Lexington KY 40536 USA Institute for Biomedical Informatics University of Kentucky Lexington KY 40536 USA Department of Molecular and Cellular Biochemistry University of Kentucky Lexington KY 40536 USA Department of Statistics University of Kentucky Louisville KY

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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026

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The Lancet Global Health 2023年第3期11卷 e385-e413页

作者： Micah, Angela E. Bhangdia, Kayleigh Cogswell, Ian E. Lasher, Dylan Lidral-Porter, Brendan Maddison, Emilie R. Nguyen, Trang Nhu Ngoc Patel, Nishali Pedroza, Paola Solorio, Juan Stutzman, Hayley Tsakalos, Golsum Wang, Yifeng Warriner, Wesley Zhao, Yingxi Zlavog, Bianca S. Abbafati, Cristiana Abbas, Jaffar Abbasi-Kangevari, Mohsen Abbasi-Kangevari, Zeinab Abdelmasseh, Michael Abdulah, Deldar Morad Abedi, Aidin Abegaz, Kedir Hussein Abhilash, E.S. Aboagye, Richard Gyan Abolhassani, Hassan Abrigo, Michael R.M. Abubaker Ali, Hiwa Abu-Gharbieh, Eman Adem, Mohammed Hussien Afzal, Muhammad Sohail Ahmadi, Ali Ahmed, Haroon Ahmed Rashid, Tarik Aji, Budi Akbarialiabad, Hossein Akelew, Yibeltal Al Hamad, Hanadi Alam, Khurshid Alanezi, Fahad Mashhour Alanzi, Turki M. Al-Hanawi, Mohammed Khaled Alhassan, Robert Kaba Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Amare, Azmeraw T. Ameyaw, Edward Kwabena Amini-Rarani, Mostafa Amu, Hubert Ancuceanu, Robert Andrei, Tudorel Anwar, Sumadi Lukman Appiah, Francis Aqeel, Muhammad Arabloo, Jalal Arab-Zozani, Morteza Aravkin, Aleksandr Y. Aremu, Olatunde Aruleba, Raphael Taiwo Athari, Seyyed Shamsadin Avila-Burgos, Leticia Ayanore, Martin Amogre Azari, Samad Baig, Atif Amin Bantie, Abere Tilahun Barrow, Amadou Baskaran, Pritish Basu, Sanjay Batiha, Abdul-Monim Mohammad Baune, Bernhard T. Berezvai, Zombor Bhardwaj, Nikha Bhardwaj, Pankaj Bhaskar, Sonu Boachie, Micheal Kofi Bodolica, Virginia Botelho, João Silva Botelho Braithwaite, Dejana Breitborde, Nicholas J.K. Busse, Reinhard Cahuana-Hurtado, Lucero Catalá-López, Ferrán Chansa, Collins Charan, Jaykaran Chattu, Vijay Kumar Chen, Simiao Chukwu, Isaac Sunday Dadras, Omid Dandona, Lalit Dandona, Rakhi Dargahi, Abdollah Debela, Sisay Abebe Denova-Gutiérrez, Edgar Desye, Belay Dharmaratne, Samath Dhamminda Diao, Nancy Doan, Linh Phuong Dodangeh, Milad dos Santos, Wendel Mombaque Doshmangir, Leila Dube, John Eini, Ebrahim El Sayed Zaki, Maysaa El Tantawi, Maha Enyew, Daniel Berhanie Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Applied Mathematics University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Nuffield Department of Medicine University of Oxford Oxford United Kingdom Department of Juridical and Economic Studies La Sapienza University Rome Italy Antai College of Economics Shanghai Jiao Tong University Shanghai China Non-communicable Diseases Research Center Tehran University of Medical Sciences Tehran Iran Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Center Tehran University of Medical Sciences Tehran Iran Children’s Medical Center Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Tehran Heart Center Tehran University of Medical Sciences Tehran Iran Faculty of Medicine Tehran University of Medical Sciences Tehran Iran National Institute for Health Research Tehran University of Medical Sciences Tehran Iran Department of Pharmacology Tehran University of Medical Sciences Tehran Iran Department of Cardiology Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Center Tehran University of Medical Sciences Tehran Iran Digestive Diseases Research Institute Tehran University of Medical Sciences Tehran Iran Department of Neurology Tehran University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Department of Epidemiology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Health Economics and Statistics Shahid Beheshti University of Medical Sciences Tehran Iran Department of Neurosurgery Shahid Beheshti University of Medical Sciences Tehran Iran Ophthalmic R

Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic;characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic;and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods: In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending: development assistance for health (DAH), government spending, out-of-pocket spending, and prepaid private spending across 204 countries and territories. We used the Organisation for Economic Co-operation and Development (OECD)'s Creditor Reporting System (CRS) and the WHO Global Health Expenditure Database (GHED) to estimate spending. We estimated development assistance for general health, COVID-19 response, and pandemic preparedness and response using a keyword search. Health spending estimates were combined with estimates of resources needed for pandemic prevention and preparedness to analyse future health spending patterns, relative to need. Findings: In 2019, at the onset of the COVID-19 pandemic, US$9·2 trillion (95% uncertainty interval [UI] 9·1–9·3) was spent on health worldwide. We found great disparities in the amount of resources devoted to health, with high-income countries spending $7·3 trillion (95% UI 7·2–7·4) in 2019;293·7 times the $24·8 billion (95% UI 24·3–25·3) spent by low-income countries in 2019. That same year, $43·1 billion in development assistance was provided

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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Bone Remodeling: Theranostic Bioabsorbable Bone Fixation Plate with Drug‐Layered Double Hydroxide Nanohybrids (Adv. Healthcare Mater. 21/2016)

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Advanced Healthcare Materials 2016年第21期5卷

作者： Myung Hun Kim Woojune Hur Goeun Choi Hye Sook Min Tae Hyun Choi Young Bin Choy Jin‐Ho Choy Center for Intelligent Nano‐Bio Materials (CINBM) Department of Chemistry and Nano Science Ewha Womans University Seoul 03760 Republic of Korea Interdisciplinary Program in Bioengineering College of Engineering Seoul National University Seoul 08826 Republic of Korea Biomedical Research Institute Seoul National University Hospital Seoul 03080 Republic of Korea Department of Plastic and Reconstructive Surgery Institute of Human‐Environment Interface Biology College of Medicine Seoul National University Seoul 03080 Republic of Korea Department of Preventive Medicine Graduate School of Public Health Seoul National University Seoul 08826 Korea Institute of Medical and Biological Engineering Medical Research Center and Department of Biomedical Engineering College of Medicine Seoul National University Seoul 03080 Republic of Korea

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Automatic stress-relieving music recommendation system based on photoplethysmography-derived heart rate variability analysis

Automatic stress-relieving music recommendation system based...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Il-hyung Shin Jaepyeong Cha Gyeong Woo Cheon Choonghee Lee Seung Yup Lee Hyung-Jin Yoon Hee Chan Kim Interdisciplinary Program Biomedical Engineering Major Graduate School Seoul National University Department of Electrical and Computer Engineering Johns Hopkins University Interdisciplinary Program Bioengineering Major Graduate School Seoul National University Department of Biomedical Engineering University of Michigan Department of Biomedical Engineering College of Medicine Seoul National University

ISBN: (纸本)9781424479276

This paper presents an automatic stress-relieving music recommendation system (ASMRS) for individual music listeners. The ASMRS uses a portable, wireless photoplethysmography module with a finger-type sensor, and a program that translates heartbeat signals from the sensor to the stress index. The sympathovagal balance index (SVI) was calculated from heart rate variability to assess the user's stress levels while listening to music. Twenty-two healthy volunteers participated in the experiment. The results have shown that the participants' SVI values are highly correlated with their prespecified music preferences. The sensitivity and specificity of the favorable music classification also improved as the number of music repetitions increased to 20 times. Based on the SVI values, the system automatically recommends favorable music lists to relieve stress for individuals.

关键词： Heart rate variability Stress Recommender systems Indexes Multiple signal classification Educational institutions Music

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Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Abstracts

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FLUIDS AND BARRIERS OF THE CNS 2017年第SUPPL 2期14卷 27-27页

作者： [Anonymous] The Jerzy Kukuczka Academy of Physical Education Katowice Poland The Institute of Animal Physiology and Food Research Polish Academy of Sciences Olsztyn Poland University of Miami Miami FL USA Institute of Pharmaceutical Science King’s College London London United Kingdom Department of Ophthalmology and Molecular and Integrative Physiology The University of Michigan Ann Arbor MI USA Department of Internal Medicine and Cardiology The University of Michigan Ann Arbor MI USA School of Medicine Department of Cellular and Molecular Medicine Koc University Istanbul Turkey Department of Cellular and Molecular Medicine Medical Faculty Koc University Istanbul Turkey Department of Neuroscience School of Medicine Koc University Istanbul Turkey Department of Neuroscience Medical Faculty Koc University Istanbul Turkey Department of Laboratory Animals Science Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey Department of Neuroscience Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey School of Medicine Koc University Istanbul Turkey Department of Forensic Science Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Histology and Embryology School of Medicine Koc University Istanbul Turkey Department of Histology and Embryology Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Physiology School of Medicine Koc University Istanbul Turkey Theodor Kocher Institute University of Bern Bern Switzerland Institute of Veterinary Physiology Vetsuisse Faculty University of Zurich Zurich Switzerland Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Zurich Center of Integrative Human Physiology University of Zurich Zurich Switzerland Institute for Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Institute of Veterinary Physiology Univer

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Ballistocardiography for Nonintrusive Sleep Structure Estimation

Ballistocardiography for Nonintrusive Sleep Structure Estima...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Kwang Suk Park Su Hwan Hwang Da Woon Jung Hee Nam Yoon Won Kyu Lee Department of Biomedical Engineering Seoul National University Interdisciplinary Program of Bioengineering Graduate School Seoul National University

ISBN: (纸本)9781424479276

Based on the its nonintrusive characteristics, ballistocardiography (BCG) has applied in the estimation of sleep structure without attaching any sensors to the subject's body. Loadcell or polyvinylidenefluoride (PVDF) film sensors are installed on the mattress for the monitoring of BCG. BCG peak was detected and heart rate variability parameters are derived. Parameters representing sleep structure and quality are estimated using these parameters. Sleep efficiency, four stages of sleep structure and sleep onset latency are estimated and results are compared with the results derived from polysomnographic recording.

关键词： Sleep apnea Heart rate Estimation Electrocardiography biomedical monitoring Blood pressure

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A programmable Acoustic Stimuli and Auditory Evoked Potential Measurement System for Objective Tinnitus Diagnosis Research

A Programmable Acoustic Stimuli and Auditory Evoked Potentia...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Yunseo Ku Joong Woo Ahn Chiheon Kwon Myung-Whan Suh Jun Ho Lee Seung Ha Oh Hee Chan Kim Samsung Electronics Samsung Advanced Institute of Technology Suwon Korea Interdisciplinary Program of Bioengineering Seoul National University Graduate School Seoul Korea Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University Hospital Seoul Department of Biomedical Engineering Seoul National University College of Medicine Seoul Korea

This paper presents the development of a single platform that records auditory evoked potential synchronized to specific acoustic stimuli of the gap prepulse inhibition method for objective tinnitus diagnosis research. The developed system enables to program various parameters of the generated acoustic stimuli. Moreover, only by simple filter modification, the developed system provides high flexibility to record not only short latency auditory brainstem response but also late latency auditory cortical response. The adaptive weighted averaging algorithm to minimize the time required for the experiment is also introduced. The results show that the proposed algorithm can reduce the number of the averaging repetitions to 70% compared with conventional ensemble averaging method.

关键词： Acoustics Acoustic measurements Noise measurement Noise Electrodes Educational institutions Animals

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Accuracy assessment of different finger placements for cardiopulmonary resuscitation on infants

Accuracy assessment of different finger placements for cardi...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Jiheum Park Chiyul Yoon Jae Yun Jung Do Kyun Kim Young Ho Kwak Jung Chan Lee Hee Chan Kim Interdisciplinary Program of Bioengineering Seoul National University Graduate School Seoul Korea Department of Emergency Medicine Seoul National University Hospital Seoul Korea Department of Emergency Medicine Seoul National University Hospital Seoul 110-744 Korea Department of Emergency Medicine Seoul National University College of Medicine Seoul Korea Department of Biomedical Engineering Seoul National University Hospital Seoul Korea

ISBN: (纸本)9781479921324

The assessment of cardiopulmonary resuscitation (CPR) is important for training as well as CPR related research to validate new method or to confirm efficacy of existing one. Infant CPR, in particular, has been received great attention due to its controversy over appropriateness of or superiority between two different methods, two-finger (TF) and two-thumb (TT) CPR, suggested by the resuscitation council. Accordingly, the development of assessment tool that is capable of reliably investigating different CPR techniques has become critical. One of the most challenging task in the infant CPR is to provide consistent and accurate finger placement throughout the performance. Here, we suggest a new method to measure accuracy of the finger placement for both TF and TT CPR using manikin-integrated digital measuring system developed in the previous study. Center of forces of force sensitive resistance sensors used for assessing different finger placements were measured in each compression and scattered on 2D plane to quantitatively and qualitatively probe the finger position. The appearance of the scattered data turned out to be significantly different depending on the performance capability. In the comparison between beginners and experts, stdY and meanDist were significant parameters differentiating these two groups for both techniques, meaning beginners are poor at providing consistent forces along y direction and targeting a specific region while relatively good at balancing in x direction.

关键词： Sensors Pediatrics Thumb Force Accuracy Correlation

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Temporal and Steady State Acoustic Field in a Cell Culture Well: Simulation

Temporal and Steady State Acoustic Field in a Cell Culture W...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Min Joo Choi Gwan Suk Kang Tetsuya Kodama Andrew J. Coleman Interdisciplinary Postgraduate Program of Biomedical Engineering and Department of Medicine Jeju National University Interdisciplinary Postgraduate Program of Biomedical Engineering Jeju National University Graduate School of Biomedical Engineering Tohoku University Department of Medical Physics Guy's & St Thomas' NHS Foundation Trust

ISBN: (纸本)9781457702150

The present study was to understand the true power irradiated to the cell line cultured on a culture well, in relation to the nominal power from ultrasonic transducer, and to characterize the temporal variations of the acoustic pressure exerted on the cell. Numerical simulation was carried out for a typical-culture well exposed to 1 MHz continuous ultrasound generated by a circular transducer contact underneath the well. The results showed that the ultrasonic pressure exposed to the cell layer in the well was 6.7 times larger than the nominal pressure of the ultrasonic transducer. The ultrasonic pressure in the transient period rose rapidly and was widely variable, and the temporal peak was even greater than that of the steady state period. This suggests that the cells undergo characteristically different ultrasonic exposure between the transient and the steady state period.

关键词： Cell culture ultrasonic transducers steady-state period Power rating sound pressure acoustic field Cell Line temporal variations true power Steady state

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