Recent studies on molecular level classification of tissues have produced remarkable results, and indicated that gene expression assays could significantly aid in the development of efficient cancer diagnosis and clas...
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(纸本)9780769530383
Recent studies on molecular level classification of tissues have produced remarkable results, and indicated that gene expression assays could significantly aid in the development of efficient cancer diagnosis and classification platforms. However, cancer classification based on the DNA array data is still a difficult problem. The main challenge is the overwhelming number of genes relative to the number of training samples. It makes accurate classification of data more difficult. This paper applies genetic algorithms (GA) with an initial solution provided by t- statistics (t-GA) for selecting a group of relevant genes from cancer microarray data. The decision tree based cancer classifier is then built on top of these selected genes. The performance of this approach is evaluated by comparing with other gene selection methods using the publicly available gene expression datasets. Experimental results indicate that t-GA has the highest accurate rate among different methods. The Z-score figure also shows that the gene selection operation provided by t-GA is reproducible.
The National Institute of Health and the US FDA have regulations on the inclusion of minorities in research, and guidelines on how to conduct and report subgroup analyses among each racial and ethnic group. Although h...
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An exploratory study used Ansoff's strategic planning model as a framework to assess perceived effectiveness of information systems in supporting strategic business plan development at Air Force medical treatment ...
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In recent years, the media has portrayed long-term care in a negative light, with exposè news stories on skilled nursing facilities, personal care homes, and hospitals that provide long-term care. There have been...
In recent years, the media has portrayed long-term care in a negative light, with exposè news stories on skilled nursing facilities, personal care homes, and hospitals that provide long-term care. There have been few positive news stories to counter the negative ones, and there is concern that the public perception of long-term care is inaccurate. The authors conducted the following study to evaluate how the West Virginia consumer perceives and defines long-term care and if there is a difference in that perception as compared with healthcare workers' perceptions and definitions of long-term care. The results of the study indicate that the respondents' education level, not occupation, has the most significant influence on respondents' definitions and perceptions of long-term care. Respondents felt that although media articles are informative, they are not accurate, and that long-term care is a needed service they would consider both for themselves and for a loved one. The results of the study suggest that current marketing strategies employed by nursing homes are working, as respondents largely believe that long-term care is provided in nursing homes and that they would likely seek care there if needed.
The number of veterans obtaining healthcare services at Huntington Veteran's administration Medical Center (HVAMC) had significantly increased over the five-year span from fiscal year 2000 through fiscal year 2004...
The number of veterans obtaining healthcare services at Huntington Veteran's administration Medical Center (HVAMC) had significantly increased over the five-year span from fiscal year 2000 through fiscal year 2004. The authors' purpose in this study was to determine changes in outpatient satisfaction levels at HVAMC over that five-year period. The authors assessed the following specific measures of patient satisfaction: courtesy, access, patient preferences, coordination of care, education and information, emotional support, overall quality, pharmacy services, and overall satisfaction. Of the 17,000 patients meeting the criteria, 630 were randomly selected;195 patients completed surveys, resulting in a 31% response rate. Results demonstrated an overall significantly higher level of patient satisfaction than five years previously. On the basis of these results, the medical center administration can probably conclude that any process he improvements made over the five-year period have been successful.
This article reviews the way in which the spread of computing technology has impacted the search and seizure policies of relevant U.S. government agencies. Among the changes that have occurred is a total redesign by t...
This article reviews the way in which the spread of computing technology has impacted the search and seizure policies of relevant U.S. government agencies. Among the changes that have occurred is a total redesign by the Justice Department of its search and seizure guidelines and policies. the article discusses numerous questions that involve search and seizure procedures as they pertain to the use of computing technology.
Adequate protection of an organization's information assets is becoming more valued, especially in a time when protecting these assets has become much more difficult. Information security problems are increasing g...
Adequate protection of an organization's information assets is becoming more valued, especially in a time when protecting these assets has become much more difficult. Information security problems are increasing globally because of several interrelated trends, including the move to distributed computing, the growth of the Internet, and the cash market that now exists in information. Conducting a rigorous, quantitative risk analysis is the single most important step in the protection of information.
Six theoretical perspectives on work design are examined for their contributions to our understanding of how work is organized and designed in organizations: sociotechnical systems theory process improvement, adaptive...
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This paper proposes a five-stage life cycle model to describe business development from birth to death with the five elements theory. A five-stage model, including birth, survival, success, decline, and renewal, is de...
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The search for effective governance and management of telecenter initiatives is an important concern for policy makers. However, so far this topic has been underresearched. This article aims to fill the gap by studyin...
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