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Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis (vol 50, pg 1368, 2020)

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PSYCHOLOGICAL MEDICINE 2020年第16期50卷 2816-2816页

作者： Wu, Yin Levis, Brooke Riehm, Kira E. Saadat, Nazanin Levis, Alexander W. Azar, Marleine Rice, Danielle B. Boruff, Jill Cuijpers, Pim Gilbody, Simon Ioannidis, John P. A. Kloda, Lorie A. McMillan, Dean Patten, Scott B. Shrier, Ian Ziegelstein, Roy C. Akena, Dickens H. Arroll, Bruce Ayalon, Liat Baradaran, Hamid R. Baron, Murray Bombardier, Charles H. Butterworth, Peter Carter, Gregory Chagas, Marcos H. Chan, Juliana C. N. Cholera, Rushina Conwell, Yeates de Manvan Ginkel, Janneke M. Fann, Jesse R. Fischer, Felix H. Fung, Daniel Gelaye, Bizu Goodyear-Smith, Felicity Greeno, Catherine G. Hall, Brian J. Harrison, Patricia A. Harter, Martin Hegerl, Ulrich Hides, Leanne Hobfoll, Stevan E. Hudson, Marie Hyphantis, Thomas Inagaki, Masatoshi Jette, Nathalie Khamseh, Mohammad E. Kiely, Kim M. Kwan, Yunxin Lamers, Femke Liu, Shen-Ing Lotrakul, Manote Loureiro, Sonia R. Lowe, Bernd McGuire, Anthony Mohd-Sidik, Sherina Munhoz, Tiago N. Muramatsu, Kumiko Osorio, Flavia L. Patel, Vikram Pence, Brian W. Persoons, Philippe Picardi, Angelo Reuter, Katrin Rooney, Alasdair G. Santos, Ina S. Shaaban, Juwita Sidebottom, Abbey Simning, Adam Stafford, Lesley Sung, Sharon Tan, Pei Lin Lynnette Turner, Alyna van Weert, Henk C. White, Jennifer Whooley, Mary A. Winkley, Kirsty Yamada, Mitsuhiko Benedetti, Andrea Thombs, Brett D. [a1]Lady Davis Institute for Medical Research Jewish General Hospital Montréal Québec Canada [a2]Department of Psychiatry McGill University Montréal Québec Canada [a3]Department of Epidemiology Biostatistics and Occupational Health McGill University Montréal Québec Canada [a4]Department of Psychology McGill University Montréal Québec Canada [a5]Schulich Library of Physical Sciences Life Sciences and Engineering McGill University Montreal Quebec Canada [a6]Department of Clinical Neuro and Developmental Psychology Amsterdam Public Health Research Institute Vrije Universiteit Amsterdam the Netherlands [a7]Hull York Medical School and the Department of Health Sciences University of York Heslington York UK [a8]Department of Medicine Department of Health Research and Policy Department of Biomedical Data Science Department of Statistics Stanford University Stanford California USA [a9]Library Concordia University Montréal Québec Canada [a10]Department of Community Health Sciences University of Calgary Calgary Alberta Canada [a11]Hotchkiss Brain Institute and O’Brien Institute for Public Health University of Calgary Calgary Alberta Canada [a12]Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA [a13]Department of Psychiatry Makerere University College of Health Sciences Kampala Uganda [a14]Department of General Practice and Primary Health Care University of Auckland Auckland New Zealand [a15]Louis and Gabi Weisfeld School of Social Work Bar Ilan University Ramat Gan Israel [a16]Endocrine Research Center Institute of Endocrinology and Metabolism Iran University of Medical Sciences Tehran Iran [a17]Ageing Clinical & Experimental Research Team Institute of Applied Health Sciences School of Medicine Medical Sciences and Nutrition University of Aberdeen Aberdeen Scotland UK [a18]Department of Medicine McGill University Montréal Québec Canada [a19]Department of Rehabilitation Medicine University of Washington S

BackgroundItem 9 of the Patient health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasingly used in research. We assessed equivalency of total score correlations and the diagnostic accuracy to detect major depression of the PHQ-8 and *** conducted an individual patient data meta-analysis. We fit bivariate random-effects models to assess diagnostic ***16 742 participants (2097 major depression cases) from 54 studies were included. The correlation between PHQ-8 and PHQ-9 scores was 0.996 (95% confidence interval 0.996 to 0.996). The standard cutoff score of 10 for the PHQ-9 maximized sensitivity + specificity for the PHQ-8 among studies that used a semi-structured diagnostic interview reference standard (N = 27). At cutoff 10, the PHQ-8 was less sensitive by 0.02 (−0.06 to 0.00) and more specific by 0.01 (0.00 to 0.01) among those studies (N = 27), with similar results for studies that used other types of interviews (N = 27). For all 54 primary studies combined, across all cutoffs, the PHQ-8 was less sensitive than the PHQ-9 by 0.00 to 0.05 (0.03 at cutoff 10), and specificity was within 0.01 for all cutoffs (0.00 to 0.01).ConclusionsPHQ-8 and PHQ-9 total scores were similar. Sensitivity may be minimally reduced with the PHQ-8, but specificity is similar.

关键词： Depression diagnostic accuracy individual participant data meta-analysis meta-analysis PHQ-8 PHQ-9 screening systematic review

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Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

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Translational psychiatry 2024年第1期14卷 109页

作者： Anna H Ou Sara B Rosenthal Mazda Adli Kazufumi Akiyama Nirmala Akula Martin Alda Azmeraw T Amare Raffaella Ardau Bárbara Arias Jean-Michel Aubry Lena Backlund Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Abesh Kumar Bhattacharjee Joanna M Biernacka Pablo Cervantes Guo-Bo Chen Hsi-Chung Chen Caterina Chillotti Sven Cichon Scott R Clark Francesc Colom David A Cousins Cristiana Cruceanu Piotr M Czerski Clarissa R Dantas Alexandre Dayer Maria Del Zompo Franziska Degenhardt J Raymond DePaulo Bruno Étain Peter Falkai Frederike Tabea Fellendorf Ewa Ferensztajn-Rochowiak Andreas J Forstner Louise Frisén Mark A Frye Janice M Fullerton Sébastien Gard Julie S Garnham Fernando S Goes Maria Grigoroiu-Serbanescu Paul Grof Oliver Gruber Ryota Hashimoto Joanna Hauser Urs Heilbronner Stefan Herms Per Hoffmann Andrea Hofmann Liping Hou Stephane Jamain Esther Jiménez Jean-Pierre Kahn Layla Kassem Tadafumi Kato Sarah Kittel-Schneider Barbara König Po-Hsiu Kuo Ichiro Kusumi Nina Lackner Gonzalo Laje Mikael Landén Catharina Lavebratt Marion Leboyer Susan G Leckband Carlos A López Jaramillo Glenda MacQueen Mario Maj Mirko Manchia Cynthia Marie-Claire Lina Martinsson Manuel Mattheisen Michael J McCarthy Susan L McElroy Francis J McMahon Philip B Mitchell Marina Mitjans Francis M Mondimore Palmiero Monteleone Caroline M Nievergelt Markus M Nöthen Tomas Novák Urban Ösby Norio Ozaki Sergi Papiol Roy H Perlis Claudia Pisanu James B Potash Andrea Pfennig Daniela Reich-Erkelenz Andreas Reif Eva Z Reininghaus Marcella Rietschel Guy A Rouleau Janusz K Rybakowski Martin Schalling Peter R Schofield K Oliver Schubert Thomas G Schulze Barbara W Schweizer Florian Seemüller Giovanni Severino Tatyana Shekhtman Paul D Shilling Kazutaka Shimoda Christian Simhandl Claire M Slaney Alessio Squassina Thomas Stamm Pavla Stopkova Sarah K Tighe Alfonso Tortorella Gustavo Turecki Eduard Vieta Julia Volkert Stephanie Witt Naomi R Wray Adam Wright L Trevor Young Peter P Zandi John R Kelsoe Department of Psychiatry University of California San Diego La Jolla CA USA. Center for Computational Biology and Bioinformatics Department of Medicine University of California San Diego La Jolla CA USA. Department of Psychiatry and Psychotherapy Charité- Universitätsmedizin Berlin Campus Charité Mitte Berlin Germany. Fliedner Klinik Berlin Center for Psychiatry Psychotherapy and Psychosomatic Medicine Berlin Germany. Department of Biological Psychiatry and Neuroscience Dokkyo Medical University School of Medicine Mibu Japan. Intramural Research Program National Institute of Mental Health National Institutes of Health US Department of Health & Human Services Bethesda MD USA. Department of Psychiatry Dalhousie University Halifax NS Canada. National Institute of Mental Health Klecany Czech Republic. Discipline of Psychiatry University of Adelaide Adelaide SA Australia. Unit of Clinical Pharmacology Hospital University Agency of Cagliari Cagliari Italy. Department of Evolutive Biology Ecology and Environmental Sciences Facultat de Biologia and Institut de Biomedicina (IBUB) Universitat de Barcelona Barcelona Spain. CIBER de Salud Mental ISCIII Madrid Barcelona Catalonia Spain. Department of Mental Health and Psychiatry Mood Disorders Unit-Geneva University Hospitals Geneva Switzerland. Department of Molecular Medicine and Surgery Karolinska Institutet and Center for Molecular Medicine Karolinska University Hospital Stockholm Sweden. Department of Psychiatry and Psychotherapy University Hospital Carl Gustav Carus Medical Faculty Technische Universität Dresden Dresden Germany. Department of Psychiatry University of Münster Münster Germany. INSERM UMR-S 1144-Université Paris Cité Département de Psychiatrie et de Médecine Addictologique AP-HP Groupe Hospitalier Lariboisière-F Widal Paris France. Bipolar and Depressive Disorders Unit Institute of Neuroscience Hospital Clinic University of Barcelona IDIBAPS CIBERSAM ISCIII Barcelona Catalonia Spa

Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipolar Disorder (PGBD) sample combining transcriptomic and genomic data, we found that focal adhesion, the extracellular matrix (ECM), and PI3K-Akt signaling networks were associated with response to lithium. In this study, we replicated the results of our previous study using network propagation methods in a genome-wide association study of an independent sample of 2039 patients from the International Consortium on Lithium Genetics (ConLiGen) study. We identified functional enrichment in focal adhesion and PI3K-Akt pathways, but we did not find an association with the ECM pathway. Our results suggest that deficits in the neuronal growth cone and PI3K-Akt signaling, but not in ECM proteins, may influence response to lithium in BD.

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Influence of the mid-follicular and late luteal phases on anaerobic power in university students

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Sport Sciences for health 2017年第2期13卷 281-286页

作者： Pestana, Ezequias Rodrigues Salvador, Emanuel Péricles Pereira, Guilherme Borges Mostarda, Cristiano Teixeira Leite, Richard Diego Silva, Cristiane Rocha de Carvalho, Wellington Roberto Gomes Physical Education Department CEUMA University São Luís MA Brazil Laboratory of Studies and Research in Epidemiology Physical Activity Exercise and Sports (LAPAES) São Luís MA Brazil Post-Graduate Program in Adult and Child Health Federal University of Maranhão São Luís Brazil Physical Education Department Federal University of Maranhão São Luís MA Brazil Department of Physical Education and Sport Federal University of Espírito Santo Vitória ES Brazil Catholic University of Brasília Brasília DF Brazil

Purpose: The aim of this study was to investigate the effect of the menstrual cycle on the anaerobic power of short duration in healthy adult women. Methods: Twenty-one subjects submitted to three Wingate tests. The following indicators were assessed: anthropometric measurements, body composition, physical activity level, maximum power average, fatigue index, and heart rate. Initially, the Wilcoxon test was made for analysis of heart rate during recovery. Results: The findings suggest no statistically significant difference between the mid-follicular phase and late luteal for absolute power peak (508.19–503.29), and relative (8.95–8.80), mean absolute power (357.52–354.24) and relative (6.32–6.18), respectively. However, the maximum heart rate was lower and significant (180.48–183.90, p = 0.01) in the mid-follicular phase. Conclusion: The mid-follicular and late luteal phases of the menstrual cycle have no influence on the performance of anaerobic power of short duration in college students. © 2017, Springer-Verlag Italia.

关键词： Exercise performance Heart rate Menstrual cycle Physical activity level

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Human genetic and immunological determinants of critical COVID-19 pneumonia

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四川生理科学杂志 2021年第11期43卷 1947-1947页

作者： Qian Zhang St Giles Laboratory of Human Genetics of Infectious Diseases Rockefeller Branch The Rockefeller University New York NY USA Laboratory of Human Genetics of Infectious Diseases Necker Branch INSERM U1163 Necker Hospital for Sick Children Paris France University of Paris Imagine Institute Paris France Department of Pediatrics Necker Hospital for Sick Children Paris France Howard Hughes Medical Institute Paris France Cemil Taşcıoglu City Hospital Istanbul Turkey Laboratory of Human Genetics of Infectious Diseases Necker Branch INSERM U1163 Necker Hospital for Sick Children Paris France Imagine Institute University of Paris Paris France Al Jalila Children’s Hospital Dubai United Arab Emirates San Raffaele Telethon Institute for Gene Therapy IRCCS Ospedale San Raffaele and Vita Salute San Raffaele University Milan Italy Hospices Civils de Lyon Lyon France Helix San Mateo CA USA Department of Intensive Care Medicine Critical Care Center CHU Lille Lille France Univ. Lille CNRS Inserm CHU Lille Institut Pasteur de Lille U1019-UMR9017-CIIL-Centre d’Infection et d’Immunité deLille Lille France Shupyk National Medical Academy for Postgraduate Education Kiev Ukraine Department of Medical Microbiology University Medical Center Utrecht Utrecht The Netherlands Sidra Medicine Doha Qatar Primary Immunodeficiencies Group Department of Microbiology and Parasitology School of Medicine University of Antioquia Medellín Colombia School of Microbiology University of Antioquia Medellín Colombia IIBB-CSIC IDIBAPS Barcelona Spain Department of Immunology Second Faculty of Medicine Charles University University Hospital in Motol Prague Czech Republic Department of Immunology Dmitry Rogachev National Medical Research Center of Pediatric Hematology Oncology and Immunology Moscow Russia Pulmonology Department Cliniques Universitaires Saint-Luc Brussels Belgium Institut de Recherche Expérimentale et Clinique (IREC) Université Catholique de Louvain Brussels Belgium

SARS-CoV-2 infection is benign in most individuals but,in-10%of cases,it triggers hypoxemic COVID-19 pneumonia,which becomes critical in-3%of *** ensuing risk of death(-1%)doubles every five years from childhood onward and is-1.5 times greater in men than in *** are the molecular and cellular determinants of critical COVID-19 pneumonia?Inborn errors of type I IFNs,including autosomal TLR3 and X-linked TLR7 deficiencies,are found in-1-5%of patients with critical pneumonia under 60 years old.

关键词： pneumonia critical cases

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Resistant tuberculosis in Maranhão, Brazil: A case series

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BMC Research Notes 2016年第1期9卷 1-3页

作者： Maia, Kenia Regina Oliveira De Castro Viana, Graça Maria Da Silva, Marcos Antonio Custódio Neto Do Desterro Soares Brandão Nascimento, Maria De Souza, Victor Lima Monteiro, Silvio Gomes Graduate Program in Parasitic Biology University CEUMA São Luís MA Brazil Nucleus of Basic and Applied Immunology Department of Pathology Federal University of Maranhão São Luís MA Brazil Medicine School Federal University of Maranhão Scientific Scholarship of CNPq São Luís MA Brazil Graduate Program in Adult and Child Health Nucleus of Basic and Applied Immunology Department of Pathology Federal University of Maranhão São Luís MA Brazil Medicine School Federal University of Maranhão São Luís MA Brazil

Background: Mycobacterium tuberculosis multidrug resistance, especially against rifampicin and isoniazid, places pulmonary tuberculosis in the list of emerging diseases. The misuse of therapeutic regimens is one of its main predisposing factors. Case presentation: Four clinical cases (three were brown and one black) with multidrug-resistant tuberculosis, treated in a reference hospital in the state of Maranhão, Brazil, were reported to evaluate the importance of radiological framework on disease evolution. Conclusion: The clinical framework showed a bad evolution and drug resistance, while radiology showed lung lesions, ranging from exudative infiltrates to lung parenchyma disintegration. © 2016 Maia et al.

关键词： Anti-tuberculosis drugs Resistance Tuberculosis

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Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part three Abstracts

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PEDIATRIC RHEUMATOLOGY 2017年第1期15卷 203-259页

作者： [Anonymous] Pediatria II Reumatologia Istituto Giannina Gaslini Genoa Italy Radiologia Istituto Giannina Gaslini Genoa Italy University of Trieste Trieste Italy Division of Rheumatology Ospedale Pediatrico Bambino Gesù IRCCS Roma Italy Institute for Maternal and Child Health - IRCCS “Burlo Garofolo” Trieste Italy Pediatric Rheumatology Uludag University Medical Faculty Bursa Turkey Department of Pediatrics Nippon Medical School Tokyo Japan Division of Physiotherapy and Rehabilitaiton Faculty of Health Sciences Istanbul University Istanbul Turkey Department of Computer Engineering Gebze Institute of Technology Kocaeli Turkey Department of Pediatric Rheumatology Medical Faculty of Cerrahpasa Istanbul University Istanbul Turkey Department of Paediatric Rheumatology and Psychology Alder Hey Children’s NHS Foundation Trust Liverpool UK Department of Women’s and Children’s Health Institute of Translational Medicine Liverpool UK UK Experimental Arthritis Treatment Centre for Children University of Liverpool Liverpool UK Rheumatology Hospital for Sick Children Toronto Canada Pediatrics University of Toronto Toronto Canada Child Evaluative Health Sciences The Hospital for Sick Children Toronto Canada Lawrence S. Bloomberg Faculty of Medicine University of Toronto Toronto Canada Psychology University of Kansas Medical Center Lawrence USA Rheumatology IWK Health Center Halifax Canada Rheumatology Alberta children’s Hospital Calgary Canada Ingram School of Nursing Mcgill University Montreal Canada Child Health Evaluative Sciences Hospital for Sick Children Toronto Canada Rheumatology Children’s Hospital of Western Ontario London Canada Rheumatology CHU Ste-Justine Montreal Canada Rheumatology Montreal Children’s Hospital Montreal Canada Pediatrics Memorial University of Newfoundland St John’s Canada Pediatrics Children’s Hospital of Eastern Ontario Ottawa Canada Research Innovation and Knowledge Translation IWK Health Center Halifax Canada Pediatrics

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WAO International Scientific Conference (WISC 2016) Abstracts

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WORLD ALLERGY ORGANIZATION JOURNAL 2017年第SUPPL 1期10卷 25-25页

作者： [Anonymous] Xin Hua Hospital Shanghai Jiao Tong University School of Medicine Pediatric Respirology Shanghai China Cincinnati Childrens Hospital Medical Center Division of Allergy and Immunology Cincinnati OH USA Cincinnati Childrens Hospital Medical Center Division of Asthma Research Cincinnati OH USA Cincinnati Childrens Hospital Medical Center Division of Human Genetics Cincinnati OH USA Universidad La Salle Facultad Mexicana de Medicina Mexico City Mexico Hospital Infantil de Mexico Federico Gomez Pediatric Allergy & Clinical Immunology Mexico City Mexico Beijing TongRen Hospital Department of Otolaryngology Head and Neck Surgery Beijing China Beijing Institute of Otolaryngology Beijing Key Laboratory of Nasal Diseases Beijing China Beijing TongRen Hospital Department of Allergy Beijing China Ghent University Hospital Upper Airways Research Laboratory Ghent Belgium University of Manitoba Section of Allergy and Immunology Department of Paediatrics and Child Health Winnipeg Canada India Department of Pharmacology Pune Poona College of Pharmacy Bharati Vidyapeeth Deemed University Department of Pharmacology Erandwane Paud Road Pune 411038 Maharashtra India Brigham and Women Pulmonary Critical Care Boston MA USA Harvard University Harvard Clinical Research Institute Boston MA USA Harvard TH Chan School of Public Health Environmental Health Boston MA USA Brigham and Women’s Hospital Pulmonary Critical Care Boston MA USA National Jewish Health Pulmonary Critical Care Denver CO USA American Academy of Family Physicians Family Medicine Denver CO USA University of Minnesota Family and Community Health Minneapolis Minnesota MN USA Soonchynhyang University Respiratory-Allergy Bucheon South Korea Utah University Biology Salt Lake City UT USA Sydney University Mathematics Sydney Australia Kaohsiung Veterans General Hospital Pediatrics Kaohsiung Taiwan Kaohsiung Veterans General Hospital Cardiac Surgery Kaohsiung Taiwan Kaohsiung Veterans General Hospital Patho

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Abstracts from the Food Allergy and Anaphylaxis Meeting 2016 Abstracts

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CLINICAL AND TRANSLATIONAL ALLERGY 2017年第SUPPL 1期7卷 10-10页

作者： [Anonymous] Department of Pediatrics Children’s Hospital Roubaix France Division of Pulmonology and Allergology Department of Pediatrics Faculty of Medicine and Children’s Hospital Lille France Allergy Vigilance Network Vandoeuvre les Nancy France Université Lille 2 CHU Lille EA 2694 - Santé Publique: épidémiologie et qualité des soins Lille France Biostatistics Unit Maison Régionale de la Recherche Clinique CHRU Lille Lille France Department of Allergology Emile Durkheim Hospital Epinal France Centre d’Epidémiologie sur les Causes Médicales de Décès INSERM CHU de Bicêtre Le Kremlin-Bicêtre France The Allergy Vigilance Network University Hospital Nancy Nancy France Pediatric Pulmonology and Allergy Department Hôpital Jeanne de Flandre CHU Lille Lille France Charité - Universitätsmedizin Berlin Berlin Germany Institute for Social Medicine Epidemiology and Health Economics Charité - Universitätsmedizin Berlin Berlin Germany Institute of Social Medicine Epidemiology and Health Economics Charité Universitätsmedizin Berlin Berlin Germany Department of Dermatology and Allergology Comprehensive Allergy Center Charité Charité – Universitätsmedizin Berlin Berlin Germany Department of Dermatology and Allergy Allergie-Centrum-Charité Charité-Universiätsmedizin Berlin Berlin Germany Department of Dermatology and Allergology Comprehensive Allergy Center Charité Charité Universitätsmedizin Berlin Berlin Germany University Hospital Basel Basel Switzerland Allergy Unit Department of Dermatology University Hospital Basel Switzerland Universitätsklinikum Salzburg Salzburg Austria Department of Dermatology and Allergy Centre Odense Research Center for Anaphylaxis (ORCA) Odense University Hospital Odense Denmark Odense University Hospital Odense Denmark Serviço de ImunoalergologiaCentro Hospitalar de São João E.P.E. Porto Portugal GRIAC Research Institute University of Groningen University Medical Center Groningen Groningen The Netherlands Serviço de Imunoalergologia Centr

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Poster abstracts

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Sleep and Biological Rhythms 2016年第1期5卷 A1-A189页

作者： J. Ferrie M. Shipley F. Cappuccio E. Brunner M. Miller M. Kumari M. Marmot A. Coenen J. L. Castillo F. Araya G. Bustamante L. Montecino C. Torres S. Oporto J. Gronli E. Fiske R. Murison B. Bjorvatn E. Sorensen R. Ursin C. M. Portas S. Rajaraman A. Gribok N. Wesensten T. Balkin J. Reifman N. Dursunoglu S. Ozkurt S. Baser O. Delen S. Sarikaya P. Sadler P. Mitchell D. Françon M. Decobert B. Herve A. Richard G. Griebel P. Avenet B. Scatton G. L. Fur D. Eckert A. Jordan A. Wellman S. Smith A. Malhotra D. White D. Bruck I. Thomas A. Kritikos W. Oertel K. Stiasny-Kolster D. Garcia-Borreguero W. Poewe B. Hoegl R. Kohnen E. Schollmayer J. Keffel C. Trenkwalder A. Valle S. Roizenblatt F. Fregni P. Boggio S. Tufik K. Ward L. Robertson L. Palmer P. Eastwood D. Hillman J. Lee S. Mukherjee V. de Padova G. Barbato G. Ficca I. Zilli P. Salzarulo M. Veldi T. Hion V. Vasar M. Kull L. Nowak J. Davis Y. Latzer O. Tzischinsky S. Crowley M. Carskadon M. Anca-Herschkovitsch D. Frey J. Ortega C. Wiseman C. Farley K. Wright A. Campbell A. Neill K. Spiegel R. Leproult E. Tasali N. Scherberg E. van Cauter A. T. Noradina N. A. Karim I. Norlinah A. A. Raymond R. Sahathevan B. Hamidon E. Werth R. Poryazova R. Khatami C. Bassetti R. G. Beran L. Ainley G. Holand J. Duncan H. Kinney B. Davis B. Hood S. Frey C. Schmidt M. Hofstetter P. Peigneux C. Cajochen W.-P. Hu J.-D. Li C. Zhang L. Boehmer J. Siegel Q.-Y. Zhou Y. Sagawa H. Kondo T. Takemura H. Kanayama Y. Kaneko M. Sato T. Kanbayashi Y. Hishikawa T. Shimizu A. Viola L. James L. Schlangen D.-J. Dijk R. Andretic Y.-C. Kim K.-A. Han F. Jones R. Greenspan L. Sanford L. Yang X. Tang K. Dieter E. Uta H. Sven M. Richard N. Oyane S. Pallesen F. Holsten Y. Inoue M. Fujita N. Emura K. Kuroda N. Uchimura A. Johnston J. Astbury G. Kennedy K. Hoedlmoser M. Schabus T. Pecherstorfer S. Moser G. Gruber P. Anderer W. Klimesch N. Naidoo M. Ferber A. Pack D. Neu O. Mairesse G. Hoffmann A. Dris L. Lambrecht P. Linkowski P. Verbanck O. Le Bon N. Matsuura M. Yamao N. Adachi R. Aritomi Y. Komada H. Tanaka S. Shirak University College London London UK University College London London USA Warwick Medical School London UK Warwick Medical School Coventry USA Radboud University Nijmegen Nijmegen Netherlands Department of Neurology University of Chile Santiago Chile Neurology Service Hospital del Salvador Santiago Chile Family Health Center Juan Pablo II Santiago Chile Department of Biomedicine Section on Physiology Univeristy of Bergen Bergen Norway Department of Public Health and Primary Health Care Univeristy of Bergen Bergen Norway Department of Public Health and Primary Health Care University of Bergen Bergen Norway Norwegian Competence Center for Sleep Disorders Haukeland University Hospital Bergen Norway Department of Child and Adolescent Psychiatry Haukeland University Hospital Univeristy of Bergen Bergen Norway Department of Biomedicine University of Bergen Bergen Norway US Army Medical Research and Materiel Command Fort Detrick Frederick USA Walter Reed Army Institute of Research Silver Spring USA Department of Behavioral Biology Walter Reed Army Institute of Research Silver Spring USA Faculty Department of Pulmonology Pamukkale University Medical Denizli Turkey University of Ballarat Ballarat Australia Sanofi-Aventis Recherche et Developpement Paris France Brigham and Women’s Hospital Harvard Medical School Boston USA The University of Queensland Adelaide Australia School of Psychology University of Queensland Brisbane Australia The University of Queensland Brisbane Australia Victoria University Melbourne Australia Department of Psychology Victoria University Melbourne Australia School of Psychology Victoria University Melbourne Australia Philips-Universität Marburg Germany Philips-Universitaet-Marburg Marburg Germany Instituto de Investigaciones del Sueno Madrid Spain Universitätsklinik für Neurologie Innsbruck Austria Universitaetsklinik fuer Neurologie Innsbruck Austria IMEREM GmbH Nuernberg Germany Schwarz Pharma AG Monheim Germany

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SWIMMING AND PHYSICAL-FITNESS DURING PREGNANCY

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JOURNAL OF NURSE-MIDWIFERY 1981年第6期26卷 3-12页

作者： SIBLEY, L RUHLING, RO CAMERONFOSTER, J CHRISTENSEN, C BOLEN, T Lynn Sibley received her B.S. in Nursing from the University of Colorado Denver Colorado in 1973 and her M.S. in Parent-Child Nursing and Nurse-Midwifery from the University of Utah Salt Lake City Utah in 1980. Ms. Sibley is currently working as a clinical instructor and practicing nurse-midwifery at the University of Colorado School of Nursing Graduate Program Nurse-Midwifery Tract. Robert O. Ruhling received his Ph.D. in Exercise Physiology from Michigan State University in 1970. He spent two years on NIH Post-Doctoral Research Traineeship (Cardiovascular Physiology) at the Institute of Environmental Stress University of California Santa Barbara. In 1972 he assumed the Directorship of the Human Performance Research Laboratory in the College of Health at the University of Utah. Currently he is Professor of Physical Education and active in both teaching and research. Joyce Cameron-Foster received her B.S. in Nursing from the University of California Los Angeles California in 1958. She received her M.S. in Nursing and Nurse-Midwifery from Yale University in 1961 and her Ph.D. in Health Science from the University of Utah in 1981. Dr. Foster is currently working as an Associate Professor in the Graduate Nurse-Midwifery Program University of Utah. Carol Christensen received her Ph.D. in Physical Education from the University of Utah in 1980. Prior to coming to Utah she earned her M.A. at the University of California Santa Barbara in Ergonomics in 1976. Currently Dr. Christensen is Assistant Professor in the Department of Human Performance San Jose State University. Timothy Bolen received his B.S. degree in Education from Central Michigan University in 1977. He worked for two years with the Central Michigan University Adult Fitness Program as an Exercise Leader. He is completing requirements for his M.S. in Physical Education at the University of Utah. Currently Mr. Bolen is on the staff of the Cardiac Rehabilitation Institute at Borgess Medical Center Kalamazoo Michigan.

The influence of aerobic swin conditioning on levels of maternal physical fitness and the influence of each swim bout on selected maternal and fetal circulatory parameters were investigated. Thirteen women who met criteria for a low-risk homogeneous sample were randomly assigned to either an experimental (n = 7) or a control (n = 6) group. Experimental subjects participated in ten weeks of a swim conditioning program, while control subjects maintained their normal activities (to exclude aerobic conditioning). Fitness levels for all subjects were determined from respiratory gas analysis during graded exercise testing on a treadmill prior to and following the swim conditioning program. Testing indicated that experimental subjects were able to maintain their initial fitness levels over the twelve weeks of increasing gestation, while control subjects were not able to do so. These findings suggest the effectiveness of the swim conditioning program in countering a potential decrease in fitness levels. Importantly, maternal blood pressure, pulse, and fetal heart rate response remained within clinically normal limits during swim conditioning for experimental subjects, and during treadmill testing for all subjects.

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