Coral-like structures of the Y_(3-x)Pr_(x)Fe_(5-y)Yb_(y)O_(12),(0.00 ≤ x ≤ 0.04, 0.00 ≤ y ≤ 0.02) compound were synthesized using the sol-gel method. Structural investigation certified the YIG cubic crystal struct...
详细信息
Coral-like structures of the Y_(3-x)Pr_(x)Fe_(5-y)Yb_(y)O_(12),(0.00 ≤ x ≤ 0.04, 0.00 ≤ y ≤ 0.02) compound were synthesized using the sol-gel method. Structural investigation certified the YIG cubic crystal structure formation, without any secondary phase. It is shown that, the relatively large ionic radius of the dopant cations results in an expansion of the lattice parameter, variations in the Iona-O-Iondangle, Iona-O,Iond-O and Ionc-O bond distances and decrease in the average crystallite size. Fourier transform infrared(FTIR) and Raman measurements are essential to testify the single-phase formation of YIG crystal structure and are observed changes in the stretching and vibrational modes, respectively. The morphological study, energy dispersive spectroscopy(EDS) spectra and textural properties show corallike structures, peaks associated with Pr^(3+) and Yb^(3+) atoms and the effect of dopants on surface area,diameter, and pore volume, respectively. The optical analysis from diffuse reflectance spectra witnessed an increase in the optical gap band, a decrease in Urbach energy and blue shift in the charge transfer,correlated with the expansion of the unit cell due to the dopant's insertion in the YIG structure. A typical ferrimagnetic behavior is exhibited by the Y_(3-x)Pr_(x)Fe_(5-y)Yb_(y)O_(12)compound. The saturation magnetization(M_(s)), cubic anisotropy constant(K_(1)) and coercive field(H_(c)) increase with the Pr^(3+)cations content, as consequence of their magnetic nature and distribution around of Fe^(3+)ions due to the coexistence with the Yb^(3+). Finally, for the first time, antibacterial tests by mean of the direct contact method were performed for YIG co-doped with Pr^(3+)and Yb^(3+)and it is shown that, relatively high dosages of Pr^(3+) cations favored the activity against S. aureus, therefore, a new biological property for YIG doped with rare earths is presented.
Following the recent development of quantum machine learning techniques, the literature has reported several quantum machine learning algorithms for disease detection. This study explores the application of a hybrid q...
详细信息
Following recent developments in quantum machine learning techniques, several algorithms have been developed for disease detection. This study explored the application of a hybrid quantum-classical algorithm for class...
详细信息
Diverse cases regarding the impact, with its related factors, of the COVID-19 pandemic on mental health have been reported in previous studies. College student groups have been frequently selected as the target popula...
详细信息
Anacardium humile, known as “cajuzinho-do-cerrado,” is a native Brazilian Cerrado fruit similar to the cashew but less studied, particularly its phenolic compound content and profile. This study used a factorial des...
详细信息
We report high-quality single-crystal growth, x-ray diffraction, magnetic susceptibility [χ(T,H)], magnetization [M(H)], heat capacity [CP(T,H)], electrical resistivity [ρ(T,H)], and electron spin resonance (ESR) me...
详细信息
We report high-quality single-crystal growth, x-ray diffraction, magnetic susceptibility [χ(T,H)], magnetization [M(H)], heat capacity [CP(T,H)], electrical resistivity [ρ(T,H)], and electron spin resonance (ESR) measurements of GdAsSe as functions of temperature and magnetic field. We identify an antiferromagnetic phase transition at TN∼11.9±0.2 K and construct magnetic phase diagrams for H||ab and H||c axes based on the χ(T,H) and CP(T,H) data. Isothermal M(H) curves along the H||ab direction at 3 K exhibit a field-induced spin orientation at HC∼3.78T. Both M(H) and χ(T,H) indicate an easy-plane-type anisotropy. The Curie-Weiss analysis of the high-temperature paramagnetic χ(T) yields a negative Weiss temperature, suggesting dominant antiferromagnetic interactions between the Gd ions. Magnetic entropy reaches 83% of R ln8 at TN. The presence of residual entropy above TN and the persistence of ESR critical broadening up to ∼3TN alludes to a degree of magnetic frustration in the studied material. The ρ(T) data above TN is well fitted to the Bloch-Grüneisen theory for metals. Further, density functional theory calculations reveal an antiferromagnetic ground state where the Gd atoms are coupled ferromagnetically in the ab plane and antiferromagnetically along the c axis.
Covalent heptazine frameworks (CHFs) are widely utilized in the recent years as potential photocatalysts. However, their limited conjugated structures, low crystallinity and small surface areas have restricted the pra...
详细信息
Covalent heptazine frameworks (CHFs) are widely utilized in the recent years as potential photocatalysts. However, their limited conjugated structures, low crystallinity and small surface areas have restricted the practical photocatalysis performance. Along this line, we report herein the synthesis of a kind of mixed crystalline CHF ( m -CHF-1) with built-in heterojunction structure, which can efficiently catalyze the formic acid dehydrogenation by visible light driven photocatalysis. The m -CHF-1 is synthesized from 2,5,8-triamino-heptazine and dicyanobenzene (DCB) in the molten salts, in which DCB plays as organic molten co-solvent to promote the rapid and ordered polymerization of 2,5,8-triamino-heptazine. The m -CHF-1 is formed by embedding phenyl-linked heptazine (CHF−Ph) units in the poly(heptazine imide) (PHI) network similar to doping. The CHF−Ph combined with PHI form an effective type II heterojunction structure, which promote the directional transfer of charge carriers. And the integration of CHF−Ph makes m -CHF-1 have smaller exciton binding energy than pure PHI, the charge carriers are more easily dissociated to form free electrons, resulting in higher utilization efficiency of the carriers. The largest hydrogen evolution rate reaches a value of 42.86 mmol h −1 g −1 with a high apparent quantum yield of 24.6 % at 420 nm, which surpasses the majority of other organic photocatalysts.
Background:Resistance to standard chemotherapy is a critical problem for breast cancer patients. The ATP-binding cassette (ABC) superfamily transporters actively pump out drugs and play an important role in chemoresis...
详细信息
Background:Resistance to standard chemotherapy is a critical problem for breast cancer patients. The ATP-binding cassette (ABC) superfamily transporters actively pump out drugs and play an important role in chemoresistance. ABCB1 (ABC subfamily B, member 1, also named as multidrug resistance protein 1, MDR1) and suppressive myeloid-derived suppressor cells (MDSCs) potentially involve in chemoresistance of breast cancer. The relationship between ABCB1 and immune genes in breast cancer has not been widely studied.
Methods:Microarray and RNA sequencing data were obtained from The Cancer Genome Atlas Breast Invasive Carcinoma in Genomic Data Commons Data Portal and Gene Expression Omnibus database. A patient-derived xenograft (PDX) model of HER2 breast cancer was established to investigate the association between and immune genes in breast cancer.
Results:Expression of increased in doxorubicin-selected MCF-7/ADR cells. High expression of mRNA is correlated with lymph-node metastasis and worse overall survival in patients with breast cancer. is positively correlated with , and . In the HER2 stage IIA breast cancer PDX model, both doxorubicin and paclitaxel suppressed growth of P2 tumors. IL6, CSF1, CSF3, and PTGS2 expression were suppressed by paclitaxel but not doxorubicin. Intrasplenic MDSCs, including CD11bLy6G and CD11bLy6C cells, were more abundant than intratumor MDSCs in PDX-carrying nude mice. Clinically, the patient developed cancer recurrence after adjuvant chemotherapy with doxorubicin-based regimen and was well controlled after paclitaxel-trastuzumab combined therapy.
Conclusion:ABCB1 was a poor predictor of HER2 LN breast cancer. Regulation of immune genes by ABCB1 contributed to cancer recurrence and treatment effect. The PDX model was suitable for investigation the expression of target genes and expansion of immune cells.
Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitati...
详细信息
Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensors and propose promising solutions. We first analyze continued...challenges in achieving satisfactory sensing performance for real-world applications and then summarize issues in compatible sensor-biology interfaces, followed by brief discussions on powering and connecting sensor networks. Issues en route to commercialization and for sustainable growth of the sector are also analyzed, highlighting environmental concerns and emphasizing nontechnical issues such as business, regulatory, and ethical considerations. Additionally, we look at future intelligent flexible sensors. In proposing a comprehensive roadmap, we hope to steer research efforts towards common goals and to guide coordinated development strategies from disparate communities. Through such collaborative
暂无评论