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检索条件"机构=Graduate Program in Biochemistry"
832 条 记 录,以下是41-50 订阅
排序:
A Medicinal Chemistry Perspective on Excitatory Amino Acid Transporter 2 Dysfunction in Neurodegenerative Diseases(vol 66, pg 2330, 2023)
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JOURNAL OF MEDICINAL CHEMISTRY 2023年 第4期66卷 2330-2346页
作者: Fontana, Igor C. Souza, Debora G. Souza, Diogo O. Gee, Antony Zimmer, Eduardo R. Bongarzone, Salvatore School of Biomedical Engineering and Imaging Sciences St Thomas’ Hospital King’s College London London SE1 7EH United Kingdom Graduate Program in Biological Sciences: Biochemistry Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 90035-003 Porto Alegre Brazil Division of Clinical Geriatrics Center for Alzheimer Research Department of Neurobiology Care Sciences and Society Karolinska Institutet Blickagången 16 - Neo floor seventh 141 83 Stockholm Sweden Brain Institute of Rio Grande do Sul Pontifical Catholic University of Rio Grande do Sul Av. Ipiranga 6681 Porto Alegre Brazil Department of Biochemistry Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 90035-003 Porto Alegre Brazil Department of Pharmacology Universidade Federal do Rio Grande do Sul Av. Sarmento Leite 500 sala 90035-003 Porto Alegre Brazil Graduate Program in Biological Sciences: Biochemistry (PPGBioq) and Pharmacology and Therapeutics (PPGFT) Universidade Federal do Rio Grande do Sul Av. Sarmento Leite 500 sala 305 Porto Alegre Brazil McGill University Research Centre for Studies in Aging McGill University Montreal Quebec H4H 1R3 Canada
The excitatory amino acid transporter 2 (EAAT2) plays a key role in the clearance and recycling of glutamate - the major excitatory neurotransmitter in the mammalian brain. EAAT2 loss/dysfunction triggers a cascade of... 详细信息
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A Neuronal Activity-Boosting Microglial Function in Post-Anesthetic Emergence:How Microglial-Neuronal Crosstalk May Alter States of Consciousness
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Neuroscience Bulletin 2024年 第10期40卷 1590-1592页
作者: Jared VanderZwaag Marie-Eve Tremblay Division of Medical Sciences University of VictoriaVictoriaBCCanada Neuroscience Graduate Program University of VictoriaVictoriaBCCanada Centre for Advanced Materials and Related Technology(CAMTEC) University of VictoriaVictoriaBCCanada Département de médecine moléculaire UniversitéLavalQuébec CityQCCanada Axe Neurosciences Centre de Recherche du CHU de QuébecUniversitéLavalQuébec CityQCCanada Neurology and Neurosurgery Department McGill UniversityMontrealQCCanada Department of Biochemistry and Molecular Biology University of British ColumbiaVancouverBCCanada Institute for Aging and Lifelong Health University of VictoriaVictoriaBCCanada
Glial cells have often been referred to as the support cells of the *** they do have numerous supportive functions,there is emerging research showing they play an active role in shaping the brain and *** the cellular ... 详细信息
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Another wrinkle with age: Aged collagen and intra-peritoneal metastasis of ovarian cancer
Aging and Cancer
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Aging and Cancer 2022年 第2期3卷 116-129页
作者: Harper, Elizabeth I. Hilliard, Tyvette S. Sheedy, Emma F. Carey, Preston Wilkinson, Paul Siroky, Michael D. Yang, Jing Agadi, Elizabeth Leonard, Annemarie K. Low, Ethan Liu, Yueying Biragyn, Arya Annunziata, Christina M. Stack, Mary Sharon Department of Chemistry and Biochemistry University of Notre Dame Notre Dame IN United States Harper Cancer Research Institute University of Notre Dame Notre Dame IN United States Integrated Biomedical Sciences Graduate Program University of Notre Dame Notre Dame IN United States National Institute on Aging Bethesda MD United States National Cancer Institute Bethesda MD United States
Background: Age is the most significant risk factor for ovarian cancer (OvCa), the deadliest gynecologic malignancy. Metastasizing OvCa cells adhere to the omentum, a peritoneal structure rich in collagen, adipocytes,... 详细信息
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Dysregulated microRNAs in type 2 diabetes and breast cancer:Potential associated molecular mechanisms
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World Journal of Diabetes 2024年 第6期15卷 1187-1198页
作者: Alex Cleber Improta-Caria Filipe Ferrari João Lucas Penteado Gomes Paloma Brasilio Villalta Úrsula Paula RenóSoci Ricardo Stein Edilamar M Oliveira Laboratory of Biochemistry and Molecular Biology of the Exercise Physical Education and Sport SchoolUniversity of São PauloSão Paulo 05508-030Brazil Graduate Program in Cardiology and Cardiovascular Sciences Federal University of Rio Grande do SulHospital de Clínicas de Porto AlegrePorto Alegre 90035003Brazil Laboratory of Metabolic Disorders(Labdime) School of Applied SciencesUniversity of Campinas-UNICAMPCampinas 13484-350Brazil Departments of Internal Medicine Molecular Pharmacology and PhysiologyCenter for Regenerative MedicineUSF Health Heart InstituteMorsani College of MedicineUniversity of South FloridaTampaFL 33602United States
Type 2 diabetes(T2D)is a multifaceted and heterogeneous syndrome associated with complications such as hypertension,coronary artery disease,and notably,breast cancer(BC).The connection between T2D and BC is establishe... 详细信息
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Undernutrition during development modulates endoplasmic reticulum stress genes in the hippocampus of juvenile rats: Involvement of oxidative stress
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Brain Research 2022年 第0期1797卷 000-000页
作者: Fernandes, Matheus Santos Pedroza, Anderson Apolônio de Andrade Silva, Severina Cássia de Lemos, Maria Daniele Teixeira Bernardo, Elenilson M. Pereira, Allifer R dos Santos, Tony Meireles Lagranha, Claudia Graduate Program in Neuropsychiatry and Behavioral Sciences Federal University of Pernambuco PE Recife Brazil Graduate Program in Biochemistry and Physiology Federal University of Pernambuco PE Recife Brazil Laboratory of Biochemistry and Exercise Biochemistry / CAV Federal University of Pernambuco Vitoria de Santo Antão PE Brazil Physical Education and Sport Department Federal University of Pernambuco PE Recife Brazil
To evaluate whether exercise training mitigates the deleterious effects of undernutrition during the developmental period in juvenile Wistar rats. Pregnant Wistar rats were fed with a diet containing 17 % or 8 % casei... 详细信息
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The role of exercise in brain DNA damage
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Neural Regeneration Research 2020年 第11期15卷 1981-1985页
作者: Thais Cereser Vilela Vanessa Moraes de Andrade Zsolt Radak Ricardo Aurino de Pinho Laboratory of Translational Biomedicine Graduate Program of Health SciencesUniversity of Southern Santa Catarina–UNESCCriciumaSCBrazil Research Institute of Sport Science University of Physical EducationBudapestHungary Laboratory of Exercise Biochemistry in Health Graduate Program in Health SciencesSchool of MedicinePontificia Universidade Catolica do ParanaCuritibaPRBrazil
Cells are constantly subjected to cytotoxic and genotoxic insults resulting in the accumulation of unrepaired damaged DNA,which leads to neuronal *** this way,DNA damage has been implicated in the pathogenesis of neur... 详细信息
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Freedericskz Transitions in the Nematic and Smectic ZA Phases of DIO
arXiv
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arXiv 2025年
作者: Gleeson, J.T. Sprunt, S.N. Jákli, A. Guragain, P. Twieg, R.J. Department of Physics Kent State University KentOH44242 United States Materials Science Graduate Program and Advanced Materials and Liquid Crystal Institute Kent State University KentOH44242 United States Department of Chemistry and Biochemistry Kent State University KentOH44242 United States
The remarkable material DIO presents fascinating behaviors. It has been extensively studied as one of the first materials exhibiting a ferroelectric nematic phase. However, at higher temperatures it exhibits what has ... 详细信息
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Involvement of matrix metalloproteinase 1 and urokinase-type plasminogen activator in the PKCα-p38 MAPK pathway-mediated progression of human liver cancer cells
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Drug Development Research 2023年 第4期84卷 767-776页
作者: Ye, Je-Chiuan Hsieh, Yih-Shou Chen, Pei-Ni Liu, Jer-Yuh Hsieh, Yi-Hsien Department of Bachelor's Degree Program for Indigenous Peoples in Senior Health and Care Management National Taitung University Taitung Taiwan Master Program in Biomedical Science National Taitung University Taitung Taiwan Department of Biochemistry School of Medicine Chung Shan Medical University Taichung Taiwan Clinical Laboratory Chung Shan Medical University Hospital Taichung Taiwan Institute of Medicine Chung Shan Medical University Taichung Taiwan Department of Medical Research Chung Shan Medical University Hospital Taichung Taiwan Center for Molecular Medicine China Medical University Hospital Taichung Taiwan Graduate Institute of Biomedical Sciences China Medical University Taichung Taiwan
Our previous studies have shown that the plasminogen activator (PA) and matrix metalloproteinases (MMPs) proteinase systems were highly expressed in highly malignant liver cancer cells and regulated by PKCα. This stu... 详细信息
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Chaperone proteins as ameliorators of α-synuclein-induced synaptic pathologies: insights into Parkinson’s disease
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Neural Regeneration Research 2021年 第6期16卷 1198-1199页
作者: Susan M.L.Banks Audrey T.Medeiros Rui Sousa Eileen M.Lafer Jennifer R.Morgan Department of Biology Florida Southern CollegeLakelandFLUSA Neuroscience Graduate Program Brown UniversityProvidenceRIUSA Department of Biochemistry and Structural Biology and Center for Biomedical Neuroscience The University of Texas Health Science Center at San AntonioSan AntonioTXUSA The Eugene Bell Center for Regenerative Biology&Tissue Engineering Marine Biological LaboratoryWoods HoleMAUSA
α-Synuclein accumulation causes synaptic vesicle trafficking defects and may underlie neurodegenerative disorders:Neurodegenerative disorders,such as Parkinson’s disease(PD)and other synucleinopathies,impact the liv... 详细信息
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Influence of conformational change of chain unit on the intrinsic negative thermal expansion of polymers
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Chinese Chemical Letters 2021年 第4期32卷 1515-1518页
作者: Qiangsheng Sun Ke Jin Yuhui Huang Jia Guo Thanyada Rungrotmongkol Phornphimon Maitarad Changchun Wang State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science Fudan UniversityShanghai 200433.China Biocatalyst and Environmental Biotechnology Research Unit Department of BiochemistryFaculty of Science and Program in Bioinformatics and Computational BiologyGraduate SchoolChulalongkom UniversityBangkok 10330Thailand Research Center of Nano Science and Technology Shanghai UniversityShanghai 200444China
Negative thermal expansion(NTE) behavior has roused wide interest for the control of thermomechanical properties of functional *** NTE behaviors have been found in kinds of compounds,it remains challenging for polymer... 详细信息
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