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Maintaining the Quality and Aroma of Coffee with Fuzzy Logic Coffee Roasting Machine

IOP Conference Series: Earth and Environmental Science 2020年第1期426卷

作者： Harsawardana Bayu Samodro Bharuno Mahesworo Teddy Suparyanto Don Bosco Surya Atmaja Bens Pardamean Artificial Intelligence Research and Innovation Center for Agroindustry (AIRICA) Institut Pertanian STIPER Yogyakarta Indonesia 55281 Mechatronics and AI Research & Development Center Biotechnic Innovation Yogyakarta Indonesia 55281 Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480

With the increasing global demands of coffee, Indonesia need to increase their coffee beans supply and improve the quality to maintain its position in the international coffee industry. One of the most important coffeepre-processing, coffee bean roasting, is under developed in Indonesia. Indonesia coffee farmers prefer to use the traditional cauldron to roast their coffee beans. Roasting coffee beans using traditional cauldron is inefficient and resulting unequal roasted level for the coffee beans. In this study, we proposed atemperature control system based on fuzzy logic for coffee roaster machine. The system controls the temperature in accordance with the demanded roasting level. A thermal camera is attached inside the roasting chamber to monitor the heaton the roasted coffee beans. The thermal camera is integrated with a stirring mechanism to equalise the heat among the beans.

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A VLPs based vaccine protects against Zika virus infection and prevents cerebral and testicular damage

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NPJ vaccines 2025年第1期10卷 107页

作者： Nelson Côrtes Aline Lira Jaqueline D Q Silva Evelyn Carvalho Wasim A Prates-Syed Barbara Hamaguchi Ricardo Durães-Carvalho Andrea Balan Niels O S Câmara Otavio Cabral-Marques Norbert Pardi Ester C Sabino José E Krieger Gustavo Cabral-Miranda Department of Infectious Diseases and Tropical Medicine Laboratory of Medical Investigation 46 Faculty of Medicine University of São Paulo São Paulo Brazil. Department of Immunology Institute of Biomedical Sciences University of São Paulo São Paulo Brazil. Department of Clinical and Toxicological Analyses School of Pharmaceutical Sciences University of Sao Paulo São Paulo Brazil. Department of Biophysics São Paulo School of Medicine Federal University of São Paulo São Paulo SP Brazil. Department of Microbiology Immunology and Parasitology São Paulo School of Medicine Federal University of São Paulo (UNIFESP) São Paulo SP Brazil. Department of Morphology and Genetics Federal University of São Paulo São Paulo Brazil. Interunit Bioinformatics Graduate Program Institute of Chemistry University of Sao Paulo Sao Paulo Brazil. Applied Structural Biology Laboratory Institute of Biomedical Sciences University of São Paulo São Paulo Brazil. Department of Medicine Division of Molecular Medicine Laboratory of Medical Investigation 29 Faculty of Medicine University of São Paulo São Paulo Brazil. DO'R Institute for Research São Paulo Brazil. Department of Microbiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Pathology Laboratory of Medical Investigation 46 Faculty of Medicine University of São Paulo São Paulo Brazil. Laboratory of Genetics and Molecular Cardiology Clinical Hospital Faculty of Medicine University of São Paulo Heart Institute São Paulo Brazil. Department of Infectious Diseases and Tropical Medicine Laboratory of Medical Investigation 46 Faculty of Medicine University of São Paulo São Paulo Brazil. gcabral.miranda@usp.br. Department of Immunology Institute of Biomedical Sciences University of São Paulo São Paulo Brazil. gcabral.miranda@usp.br.

Still, Zika virus (ZIKV) infection poses a substantial public health risk, especially for pregnant women and their fetuses, as it can result in congenital abnormalities and fetal mortality during pregnancy. Despite significant advances in understanding and combating ZIKV, considerable challenges remain in the fight against this flavivirus. A crucial component of this effort is the development of vaccines, none of which have yet been licensed for human use. Here, we present a comprehensive study of a novel ZIKV vaccine candidate based on virus-like particles (VLPs), designed to provide broad immunological protection against viral infection combined with safety, without the need for additional adjuvants. A self-adjuvanted VLPs-based vaccine displaying the envelope protein domain III (EDIII) of ZIKV was built. The EDIII protein was expressed in E. coli and chemically conjugated to QβVLPs. Immunization of C57BL/6 mice with two doses of the EDIII-QβVLPs vaccine elicited strong EDIII-specific Th1-based immune response. Notably, the vaccine induced neutralizing antibodies and conferred protection in type I IFN receptor-deficient (G129) mice against ZIKV challenge. Furthermore, vaccinated male mice were protected from ZIKV-induced cerebral and testicular damage, critical concerns for ZIKV pathogenesis. These findings suggest that the EDIII-QβVLP vaccine is a promising candidate for preventing ZIKV infection, with potential applications in combatting this and other emerging flaviviruses.

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Sustainability of the Water Footprint of Various Soil Types on Oil Palm Plantations

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IOP Conference Series: Earth and Environmental Science 2022年第1期998卷

作者： Lisma Safitri Hermantoro Valensi Kautsar Teddy Suparyanto Alam Ahmad Hidayat Bens Pardamean Agricultural Engineering Department Institute of Agricultural STIPER Yogyakarta 55282 Indonesia School of Earth and Environment University of Leeds Woodhouse Leeds LS2 9J Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480

There are significant studies that have quantified oil palm water footprint as an indicator of environmental sustainability but an estimation of water footprint under varying soil types furthermore is still limited. The objectives of the study were to estimate whether annual variations of soil type and yields significantly effects for the oil palm water footprint. The data from three types of soil (spodosol, inceptisol, ultisol) were collected from an oil palm plantation in Pundu village, Central Kalimantan, Indonesia. To perform the water footprint analysis we utilize water balance accounting equations via application Cropwat 8.0. From that, we determine the crop irrigation scheduling to compute the blue, green, and grey water footprint of oil palm fresh fruit bunch in the area. Our analysis found that the actual evapotranspiration of spodosol and inceptisol have the same value: 1242 mm/year whilst ultisol is 1239 mm/year. The total water footprint of oil palm varied considerably with the largest value being 1310.04 m3/ton for ultisol. The actual evapotranspiration of spodosol and inceptisol have the same value of 1242 mm/year whilst ultisol is 1239 mm/year. The higher production resulted in a lower water footprint and vice versa. Moreover, the total water footprint from ultisol soil type has the highest value due to the lowest yields. The difference in evapotranspiration value resulted in the insignificant value of total water footprint. The lower water availability, the lower water use, and the higher actual irrigation requirement in oil palm plantation yet showed the unnotable impact on water footprint in different soil types for the oil palm plantation.

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Addendum to “Hypothesis: a glycoprotein-degradation complex formed by protein–protein interaction involves cytoplasmic peptide: N -glycanase” [Biochem. Biophys. Res. Commun. 302 (2003) 1–5]

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Biochemical and Biophysical Research Communications 2003年第2期303卷 732-732页

作者： Tadashi Suzuki William J Lennarz Undergraduate Program for Bioinformatics and Systems Biology and Department of Biophysics and Biochemistry Graduate School of Science University of Tokyo and PRESTO Japan Science and Technology Corporation (JST) Hongo 7-3-1 Bunkyo-ku Tokyo 113-0033 Japan Department of Biochemistry and Cell Biology and the Institute for Cell and Developmental Biology State University of New York at Stony Brook Stony Brook NY 11794-5215 USA

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bioinformatics Pathway Analysis Pipeline for NGS Transcriptome Profile Data on Nasopharyngeal Carcinoma

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IOP Conference Series: Earth and Environmental Science 2021年第1期794卷

作者： Digdo Sudigyo Gisti Rahmawati Dicka W. Setiasari Risky H. Poluan Tjeng Wawan Cenggoro Arif Budiarto Alam Ahmad Hidayat Sri R. Indrasari Afiahayati Sofia M. Haryana Bens Pardamean Bioinformatics & Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Study Program of Biotechnology Gadjah Mada University Yogyakarta Indonesia 55281 Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Faculty of Medicine Public Health and Nursing Gadjah Mada University Yogyakarta Indonesia 55281 Department of Computer Science and Electronics Faculty of Mathematics and Natural Science Gadjah Mada University Yogyakarta Indonesia 55281 Computer Science Department BINUS Graduate Program - Master of Computer Science Program Bina Nusantara University Jakarta Indonesia 11480

Next-Generation Sequencing (NGS)-based genomics data have a huge potential to be used in transcriptomic profiling of Nasopharyngeal Carcinoma (NPC) to study the biosynthesis mechanism behind it. The high dimensionality of NGS data is the main challenge in performing the data analysis to extract useful information. In this workflow pipeline, memory-efficient Linux-based software such as HISAT2 and HTSeq are utilized to process the raw NGS data. Furthermore, Differential Expression Gene (DEG) list can be obtained by performing advanced analysis to the aligned Ribonucleic Acid (RNA) sequence using the edgeR protocol. This DEG list is one of the main inputs of biological pathway analysis that can be done in DAVID and PANTHER web-based software. Both tools generate a different pathway result related to inflammation.

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Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: From Monomers to Dodecamers†

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Angewandte Chemie 2011年第40期123卷

作者： Kuo‐Ching Chu Chien‐Tai Ren Chun‐Ping Lu Che‐Hsiung Hsu Tsung‐Hsien Sun Jeng‐Liang Han Bikash Pal Tsung‐An Chao Yung‐Feng Lin Shih‐Hsiung Wu Chi‐Huey Wong Chung‐Yi Wu Genomics Research Center Academia Sinica 128 Academia Road Section 2 Nankang Taipei 115 (Taiwan) Institute of Biological Chemistry Academia Sinica (Taiwan) Chemical Biology and Molecular Biophysics Taiwan International Graduate Program Academia Sinica 128 Academia Road Section 2 Nankang Taipei 115 (Taiwan) Institute of Bioinformatics and Structural Biology National Tsing‐Hua University Hsin‐Chu (Taiwan)

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Front Cover: Synthesis and Immunomodulatory Activity of Fluorine-Containing Bisphosphonates (ChemMedChem 4/2019)

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ChemMedChem 2019年第4期14卷 360-360页

作者： Dr. Satoshi Mizuta Mohammed S. O. Tagod Dr. Masashi Iwasaki Prof. Yoichi Nakamura Dr. Hiroaki Senju Prof. Hiroshi Mukae Prof. Craig T. Morita Prof. Yoshimasa Tanaka Center for Bioinformatics and Molecular Medicine Graduate School of Biomedical Sciences Nagasaki University 1-12-4 Sakamoto Nagasaki 852-8523 Japan Program for Nurturing Global Leaders in Tropical and Emerging Infectious Diseases Graduate School of Biomedical Sciences Nagasaki University 1-12-4 Sakamoto Nagasaki 852-8523 Japan Center for Innovation in Immunoregulative Technology and Therapeutics Graduate School of Medicine Kyoto University Yoshidakonoe-cho Kyoto 606-8501 Japan Department of Respiratory Medicine Nagasaki University School of Medicine 1-7-1 Sakamoto Nagasaki 852-8501 Japan Department of Internal Medicine and the Interdisciplinary Graduate Program in Immunology University of Iowa Carver College of Medicine Iowa City Veterans Affairs Health Care System Iowa City IA 52246 USA Hyogo College of Medicine 1-1 Mukogawa Nishinomiya Hyogo 663-8501 Japan

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Analysis of plant pattern using water balance and cimogram based on oldeman climate type

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IOP Conference Series: Earth and Environmental Science 2018年第1期195卷

作者： R E Caraka M Tahmid R M Putra A Iskandar M A Mauludin Hermansah N E Goldameir H Rohayani B Pardamean Bioinformatics and Data Science Research Center (BDSRC) Bina Nusantara University Jakarta Indonesia 11480 Indonesia Agency for Meteorology Climatology and Geophysics Indonesia Informatics Engineering STMIK AKBA Makassar Laboratory of Sociology and Extension Universitas Padjadjaran Universitas Riau Kepulauan Riau University Universitas Adiwangsa Jambi Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480

The transfer of land has an impact on the decreasing of the agricultural land area, so it is necessary to plan the right cropping pattern as an effort to increase the productivity of agricultural cultivation. Also, Climate is one of the factors influencing the determination of cropping pattern in a region. Analysis of climatic characteristics in the determination of cropping pattern not only based on oldeman climatic classification. At the same time, the study of groundwater availability for plants and climogram of climatic elements is needed in determining planting schedule which is suitable for planting and determination of irrigation water supply, either the right amount of time. This study aims to identify and build spatial of the oldeman climate classification. It also determines the cropping pattern for seasonal crops based on the calculation of water balance and climogram (rainfall and air temperature) in each type of climate oldeman district of Cirebon and surrounding areas. Data used monthly rainfall data period 1981-2010 from BMKG Jatiwangi station and air temperature data, plant coefficient and the base map of Cirebon region. The analysis method includes classification of Oldeman climate type, spatial data processing, water balance calculation by Thorntwaite & Matter method and making climogram (rainfall and temperature) with: k = p0 + p1/FC; p0 = 1.000412351; p1 = -1.073807306 and determination of planting pattern of each type of oldeman

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RETRACTION: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing (Retraction of Vol 12, art no 4624, 2021)

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NATURE COMMUNICATIONS 2022年第1期13卷 1页

作者： Laliotis, Georgios I. Chavdoula, Evangelia Paraskevopoulou, Maria D. Kaba, Abdul La Ferlita, Alessandro Singh, Satishkumar Anastas, Vollter Nair, Keith A., II Orlacchio, Arturo Taraslia, Vasiliki Vlachos, Ioannis Capece, Marina Hatzigeorgiou, Artemis Palmieri, Dario Tsatsanis, Christos Alaimo, Salvatore Sehgal, Lalit Carbone, David P. Coppola, Vincenzo Tsichlis, Philip N. Department of Cancer Biology and Genetics The Ohio State University Columbus OH USA The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus OH USA School of Medicine University of Crete Heraklion Crete Greece Department of Clinical and Experimental Medicine Bioinformatics Unit University of Catania Catania Italy Tufts Graduate School of Biomedical Sciences Program in Genetics Boston MA USA Department of Medicine Division of Hematology The Ohio State University Columbus OH USA Department of Internal Medicine Division of Medical Oncology The Ohio State University Medical Center Columbus OH USA Institute of Molecular Biology and Biotechnology Foundation for Research and Technology Hellas Heraklion Crete Greece Molecular Oncology Research Institute Tufts Medical Center Boston MA USA DIANA-Lab Hellenic Pasteur Institute Athens Greece

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Corrigendum to "Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D3 administration" [Metabolism vol. 70, May 2017, pages 31-41]

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Metabolism: clinical and experimental 2017年 74卷 41-42页

作者： Jessica A Alvarez Elizabeth Y Chong Douglas I Walker Joshua D Chandler Ellen S Michalski Ruth E Grossmann Karan Uppal Shuzhao Li Jennifer K Frediani Rabindra Tirouvanziam ViLinh T Tran Vin Tangpricha Dean P Jones Thomas R Ziegler Division of Endocrinology Metabolism & Lipids Department of Medicine Emory University School of Medicine Atlanta GA USA Center for Cystic Fibrosis and Airways Disease Research Children's Healthcare of Atlanta Atlanta GA USA. Electronic address: jessica.alvarez@emory.edu. Department of Biostatistics and Bioinformatics Rollins School of Public Health Emory University Atlanta GA USA. Division of Pulmonary Allergy Critical Care and Sleep Medicine Department of Medicine Emory University School of Medicine Atlanta GA USA. Center for Cystic Fibrosis and Airways Disease Research Children's Healthcare of Atlanta Atlanta GA USA Division of Pulmonary Allergy Critical Care and Sleep Medicine Department of Medicine Emory University School of Medicine Atlanta GA USA. Nutrition and Health Sciences Graduate Program Laney Graduate School Emory University Atlanta GA USA. College of Nursing The University of Iowa Ames IA USA. Division of Pulmonary Allergy & Immunology Cystic Fibrosis and Sleep Department of Pediatrics Emory University School of Medicine Atlanta GA USA. Center for Cystic Fibrosis and Airways Disease Research Children's Healthcare of Atlanta Atlanta GA USA Section of Endocrinology Atlanta Veterans Affairs Medical Center Atlanta GA USA.

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