检索结果-内蒙古大学图书馆

Correction to: Authors’ Reply to Letter to the Editor: Continued improvement to genetic diversity indicator for CBD

Conservation Genetics 2021年第4期22卷 537-539页

作者： Laikre, Linda Hohenlohe, Paul A. Allendorf, Fred W. Bertola, Laura D. Breed, Martin F. Bruford, Michael W. Funk, W. Chris Gajardo, Gonzalo González-Rodríguez, Antonio Grueber, Catherine E. Hedrick, Philip W. Heuertz, Myriam Hunter, Margaret E. Johannesson, Kerstin Liggins, Libby MacDonald, Anna J. Mergeay, Joachim Moharrek, Farideh O’Brien, David Ogden, Rob Orozco-terWengel, Pablo Palma-Silva, Clarisse Pierson, Jennifer Paz-Vinas, Ivan Russo, Isa-Rita M. Ryman, Nils Segelbacher, Gernot Sjögren-Gulve, Per Waits, Lisette P. Vernesi, Cristiano Hoban, Sean Division of Population Genetics Department of Zoology Stockholm University Stockholm Sweden Institute for Bioinformatics and Evolutionary Studies Department of Biological Sciences University of Idaho Moscow USA Division of Biological Sciences University of Montana Missoula USA City College of New York New York USA College of Science and Engineering Flinders University Bedford Park Australia School of Biosciences Cardiff University Cardiff Wales UK Graduate Degree Program in Ecology Department of Biology Colorado State University Fort Collins USA Universidad de Los Lagos Lab Genetics Aquaculture & Biodiversity Osorno Chile Instituto de Investigaciones en Ecosistemas y Sustentabilidad Universidad Nacional Autónoma de México Morelia Mexico School of Life and Environmental Sciences Faculty of Science The University of Sydney Sydney Australia School of Life Sciences Arizona State University Tempe USA INRAE Univ. Bordeaux Biogeco Cestas France U.S. Geological Survey Wetland and Aquatic Research Center Gainesville USA Department of Marine Sciences University of Gothenburg Tjärnö Strömstad Sweden School of Natural and Computational Sciences Massey University Auckland New Zealand The John Curtin School of Medical Research/Research School of Biology The Australian National University Acton Australia Research Institute for Nature and Forest Geraardsbergen Belgium Aquatic Ecology Evolution and Conservation KULeuven Leuven Belgium Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark Faculty of Biological Sciences Tarbiat Modares University Tehran Iran Scottish Natural Heritage Inverness UK Royal (Dick) School of Veterinary Studies and the Roslin Institute University of Edinburgh Midlothian UK Department of Plant Science Institute of Biology University of Campinas Campinas Brazil Australian Wildlife Conservancy Subiaco East Australia Laboratoire Evolution & Div

A correction to this paper has been published: https://***/10.1007/s10592-021-01376-9

关键词：

来源：评论

学校读者我要写书评

暂无评论

Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

引用

NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

来源：评论

学校读者我要写书评

暂无评论

Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

引用

Nature protocols 2024年第4期19卷 1289页

作者： Shuo Li Ran Hu Colin Small Ting-Yu Kang Chun-Chi Liu Xianghong Jasmine Zhou Wenyuan Li Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA. Bioinformatics Interdepartmental Graduate Program University of California at Los Angeles Los Angeles CA USA. Institute for Quantitative & Computational Biosciences University of California at Los Angeles Los Angeles CA USA. EarlyDiagnostics Inc. Los Angeles CA USA. Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA. XJZhou@mednet.ucla.edu. Institute for Quantitative & Computational Biosciences University of California at Los Angeles Los Angeles CA USA. XJZhou@mednet.ucla.edu. EarlyDiagnostics Inc. Los Angeles CA USA. XJZhou@mednet.ucla.edu. Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA. WenyuanLi@mednet.ucla.edu. EarlyDiagnostics Inc. Los Angeles CA USA. WenyuanLi@mednet.ucla.edu.

来源：评论

学校读者我要写书评

暂无评论

Genome wide conditional mouse knockout resources

引用

Drug Discovery Today: Disease Models 2016年 20卷 3-12页

作者： Kaloff, C. Anastassiadis, K. Ayadi, A. Baldock, R. Beig, J. Birling, M.-C. Bradley, A. Brown, S.D.M. Bürger, A. Bushell, W. Chiani, F. Collins, F.S. Doe, B. Eppig, J.T. Finnell, R.H. Fletcher, C. Flicek, P. Fray, M. Friedel, R.H. Gambadoro, A. Gates, H. Hansen, J. Herault, Y. Hicks, G.G. Hörlein, A. Hrabé de Angelis, M. Iyer, V. de Jong, P.J. Koscielny, G. Kühn, R. Liu, P. Lloyd, K.C.K. Lopez, R.G. Marschall, S. Martínez, S. McKerlie, C. Meehan, T. von Melchner, H. Moore, M. Murray, S.A. Nagy, A. Nutter, L.M.J. Pavlovic, G. Pombero, A. Prosser, H. Ramirez-Solis, R. Ringwald, M. Rosen, B. Rosenthal, N. Rossant, J. Ruiz Noppinger, P. Ryder, E. Skarnes, W.C. Schick, J. Schnütgen, F. Schofield, P. Seisenberger, C. Selloum, M. Smedley, D. Simpson, E.M. Stewart, A.F. Teboul, L. Tocchini Valentini, G.P. Valenzuela, D. West, A.P. Wurst, W. Institute of Developmental Genetics Helmholtz Zentrum Muenchen Neuherberg D-85764 Germany Biotechnology Center (BIOTEC) of the Technische Universität Dresden Dresden 01307 Germany CELPHEDIA PHENOMIN Institut Clinique de la Souris (ICS) CNRS INSERM University of Strasbourg 1 rue Laurent Fries Illkirch-Graffenstaden F-67404 France MRC Human Genetics Unit Institute of Genetics and Molecular Medicine University of Edinburgh College of Medicine and Veterinary Medicine Edinburgh EH4 2XU Scotland United Kingdom The Wellcome Trust Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridge CB101HH United Kingdom Mammalian Genetics Unit and Mary Lyon Centre MRC Harwell Harwell Science and Innovation Campus Oxfordshire OX110RD United Kingdom Monterotondo Mouse Clinic Italian National Research Council (CNR) Institute of Cell Biology and Neurobiology Monterotondo-Scalo Rome I-00015 Italy National Human Genome Research Institute National Institutes of Health Bethesda 20892 MD United States The Jackson Laboratory Bar Harbor 04609 ME United States Dell Pediatric Research Institute The University of Texas at Austin Austin 78712 TX United States University of Texas at Austin Austin 78712 TX United States National Institutes of Health Bethesda 20205 MD United States European Bioinformatics Institute (EBI) Hinxton Cambridge CB101ST United Kingdom Fishberg Department of Neuroscience Friedman Brain Institute Icahn School of Medicine at Mount Sinai New York 10029 New York United States Institut de Génétique et de Biologie Moléculaire et Cellulaire Université de Strasbourg 1 rue Laurent Fries Illkirch 67404 France Centre National de la Recherche Scientifique UMR7104 Illkirch France Institut National de la Santé et de la Recherche Médicale U964 Illkirch France Université de Strasbourg 1 rue Laurent Fries Illkirch 67404 France University of Manitoba Manitoba Institute of Cell Biology Winnipeg R3EOV9 MB Canada Institute of Epidemiology II Helmh

The International Knockout Mouse Consortium (IKMC) developed high throughput gene trapping and gene targeting pipelines that produced mostly conditional mutations of more than 18,500 genes in C57BL/6N mouse embryonic stem (ES) cells which have been archived and are freely available to the research community as a frozen resource. From this unprecedented resource more than 6000 mutant mouse strains have been generated by the IKMC in collaboration with the International Mouse Phenotyping Consortium (IMPC). In addition, a cre-driver resource was established including 250 C57BL/6 cre-inducible mouse strains. Complementing the cre-driver resource, a collection comprising 27 rAAVs expressing cre in a tissue-specific manner has also been produced. All resources are easily accessible from the IKMC/IMPC web portal (***). The IKMC/IMPC resource is a standardized reference library of mouse models with defined genetic backgrounds enabling the analysis of gene-disease associations in mice of different genetic makeup and should therefore have a major impact on biomedical research. © 2017 Elsevier Ltd

关键词：

来源：评论

学校读者我要写书评

暂无评论

Erratum: Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)

引用

Journal of biomedical science 2015年第1期22卷 60页

作者： Chuan-Pin Yang Chi-Wu Chiang Chang-Han Chen Yi-Chao Lee Mei-Hsiang Wu Yi-Huan Tsou Yu-San Yang Wen-Chang Chang Ding-Yen Lin Institute of Bioinformatics and Biosignal Transduction College of Bioscience and Biotechnology National Cheng Kung University Tainan 70101 Taiwan ROC. Institute of Molecular Medicine College of Medicine National Cheng Kung University Tainan 70101 Taiwan ROC. Infectious Diseases and Signaling Research Center National Cheng Kung University Tainan 70101 Taiwan ROC. Center for Translational Research in Biomedical Sciences Kaohsiung Chang Gung Memorial Hospital Kaohsiung 83301 Taiwan ROC. Department of Applied Chemistry National Chi Nan University Puli Nantou 54561 Taiwan ROC. Center for Neurotrauma and Neuroregeneration Taipei Medical University Taipei 11031 Taiwan ROC. Program for Neural Regenerative Medicine College of Medical Science and Technology Taipei Medical University Taipei 11031 Taiwan ROC. Department of Pharmacology College of Medicine National Cheng Kung University Tainan 70101 Taiwan ROC. Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei 11031 Taiwan ROC. Institute of Bioinformatics and Biosignal Transduction College of Bioscience and Biotechnology National Cheng Kung University Tainan 70101 Taiwan ROC. lindy@mail.ncku.edu.tw. Department of Pharmacology College of Medicine National Cheng Kung University Tainan 70101 Taiwan ROC. lindy@mail.ncku.edu.tw. Infectious Diseases and Signaling Research Center National Cheng Kung University Tainan 70101 Taiwan ROC. lindy@mail.ncku.edu.tw. Institute for Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei 11031 Taiwan ROC. lindy@mail.ncku.edu.tw.

A correction to the article 'Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)' that was published in the 2015 issue is presented.

关键词： NUCLEAR proteins BRAIN function localization

来源：评论

学校读者我要写书评

暂无评论

Patterns of somatic structural variation in human cancer genomes (vol 578, pg 112, 2020)

引用

NATURE 2023年第7948期614卷 E38-E38页

作者： Li, Yilong Roberts, Nicola D. Wala, Jeremiah A. Shapira, Ofer Schumacher, Steven E. Kumar, Kiran Khurana, Ekta Waszak, Sebastian Korbel, Jan O. Haber, James E. Imielinski, Marcin Weischenfeldt, Joachim Beroukhim, Rameen Campbell, Peter J. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK Totient Inc Cambridge MA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Haematology University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Korea Advanced Institute of Science and Technology Daejeon South Korea Department of Zoology Genetics and Physical Anthropology University of Santiago de Compostela Santiago de Compostela Spain Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) University of Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) University of Vigo Vigo Spain Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain Department of Zoology Genetics and Physical Anthropology (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) Universidade de Vigo Vigo Spain The Broad Institute of Harvard and MIT Cambridge MA USA Bioinformatics and Integrative Genomics Harvard University Cambridge MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Harvard Medical School Boston MA USA Massachusetts General Hospital Center for Cancer Research Charlestown MA USA Dana-Farber Cancer Institute Boston MA USA Department of Biostatistics and Computational Biology Dana-Farber Cancer Institute and Harvard Medical School Boston MA USA Weill Cornell Medical College New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine Ne

来源：评论

学校读者我要写书评

暂无评论

Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

Communications biology

引用

Communications biology 2021年第1期4卷 1179页

作者： Georgios I Laliotis Adam D Kenney Evangelia Chavdoula Arturo Orlacchio Abdul Kaba Alessandro La Ferlita Vollter Anastas Christos Tsatsanis Joal D Beane Lalit Sehgal Vincenzo Coppola Jacob S Yount Philip N Tsichlis Department of Cancer Biology and Genetics The Ohio State University College of Medicine Columbus Columbus OH 43210 USA. glaliot1@jhmi.edu. The Ohio State University Comprehensive Cancer Center Columbus OH 43210 USA. glaliot1@jhmi.edu. University of Crete School of Medicine Heraklion Crete 71500 Greece. glaliot1@jhmi.edu. Sidney Kimmel Comprehensive Cancer Center and Department of Oncology Johns Hopkins School of Medicine Baltimore MD 21205 USA. glaliot1@jhmi.edu. The Ohio State University Comprehensive Cancer Center Columbus OH 43210 USA. Department of Microbial Infection and Immunity and Infectious Diseases Institute The Ohio State University Columbus OH 43210 USA. Department of Cancer Biology and Genetics The Ohio State University College of Medicine Columbus Columbus OH 43210 USA. Department of Clinical and Experimental Medicine Bioinformatics Unit University of Catania Catania 95131 Italy. Tufts Graduate School of Biomedical Sciences Program in Genetics Boston MA 02111 USA. University of Crete School of Medicine Heraklion Crete 71500 Greece. Institute of Molecular Biology and Biotechnology Heraklion Crete 70013 Greece. Department of Surgery Division of Surgical Oncology Columbus OH 43210 USA. Department of Medicine Division of Hematology The Ohio State University Columbus OH 43210 USA. Department of Cancer Biology and Genetics The Ohio State University College of Medicine Columbus Columbus OH 43210 USA. Philip.tsichlis@osumc.edu. The Ohio State University Comprehensive Cancer Center Columbus OH 43210 USA. Philip.tsichlis@osumc.edu. Tufts Graduate School of Biomedical Sciences Program in Genetics Boston MA 02111 USA. Philip.tsichlis@osumc.edu.

AKT-phosphorylated IWS1 promotes Histone H3K36 trimethylation and alternative RNA splicing of target genes, including the U2AF65 splicing factor-encoding U2AF2. The predominant U2AF2 transcript, upon IWS1 phosphorylation block, lacks the RS-domain-encoding exon 2, and encodes a protein which fails to bind Prp19. Here we show that although both U2AF65 isoforms bind intronless mRNAs containing cytoplasmic accumulation region elements (CAR-E), only the RS domain-containing U2AF65 recruits Prp19 and promotes their nuclear export. The loading of U2AF65 to CAR-Elements was RS domain-independent, but RNA PolII-dependent. Virus- or poly(I:C)-induced type I IFNs are encoded by genes targeted by the pathway. IWS1 phosphorylation-deficient cells therefore, express reduced levels of IFNα1/IFNβ1 proteins, and exhibit enhanced sensitivity to infection by multiple cytolytic viruses. Enhanced sensitivity of IWS1-deficient cells to Vesicular Stomatitis Virus and Reovirus resulted in enhanced apoptotic cell death via caspase activation. Inhibition of this pathway may therefore sensitize cancer cells to oncolytic viruses.

关键词：

来源：评论

学校读者我要写书评

暂无评论

FANTOM5 CAGE profiles of human and mouse samples

引用

Scientific Data 2017年第1期4卷 170112-170121页

作者： Noguchi, Shuhei Arakawa, Takahiro Fukuda, Shiro Furuno, Masaaki Hasegawa, Akira Hori, Fumi Ishikawa-Kato, Sachi Kaida, Kaoru Kaiho, Ai Kanamori-Katayama, Mutsumi Kawashima, Tsugumi Kojima, Miki Kubosaki, Atsutaka Manabe, Ri-Ichiroh Murata, Mitsuyoshi Nagao-Sato, Sayaka Nakazato, Kenichi Ninomiya, Noriko Nishiyori-Sueki, Hiromi Noma, Shohei Saijyo, Eri Saka, Akiko Sakai, Mizuho Simon, Christophe Suzuki, Naoko Tagami, Michihira Watanabe, Shoko Yoshida, Shigehiro Arner, Peter Axton, Richard A. Babina, Magda Kenneth Baillie, J. Barnett, Timothy C. Beckhouse, Anthony G. Blumenthal, Antje Bodega, Beatrice Bonetti, Alessandro Briggs, James Brombacher, Frank Carlisle, Ailsa J. Clevers, Hans C. Davis, Carrie A. Detmar, Michael Dohi, Taeko Edge, B. Albert S. Edinger, Matthias Ehrlund, Anna Ekwall, Karl Endoh, Mitsuhiro Enomoto, Hideki Eslami, Afsaneh Fagiolini, Michela Fairbairn, Lynsey Farach-Carson, Mary C. Faulkner, Geoffrey J. Ferrai, Carmelo Fisher, Malcolm E. Forrester, Lesley M. Fujita, Rie Furusawa, Jun-Ichi Geijtenbeek, Teunis B. Gingeras, Thomas Goldowitz, Daniel Guhl, Sven Guler, Reto Gustincich, Stefano Ha, Thomas J. Hamaguchi, Masahide Hara, Mitsuko Hasegawa, Yuki Herlyn, Meenhard Heutink, Peter Hitchens, Kelly J. Hume, David A. Ikawa, Tomokatsu Ishizu, Yuri Kai, Chieko Kawamoto, Hiroshi Kawamura, Yuki I. Kempfle, Judith S. Kenna, Tony J. Kere, Juha Khachigian, Levon M. Kitamura, Toshio Klein, Sarah Peter Klinken, S. Knox, Alan J. Kojima, Soichi Koseki, Haruhiko Koyasu, Shigeo Lee, Weonju Lennartsson, Andreas MacKay-Sim, Alan Mejhert, Niklas Mizuno, Yosuke Morikawa, Hiromasa Morimoto, Mitsuru Moro, Kazuyo Morris, Kelly J. Motohashi, Hozumi Mummery, Christine L. Nakachi, Yutaka Nakahara, Fumio Nakamura, Toshiyuki Nakamura, Yukio Nozaki, Tadasuke Ogishima, Soichi Ohkura, Naganari Ohno, Hiroshi Ohshima, Mitsuhiro Okada-Hatakeyama, Mariko Okazaki, Yasushi Orlando, Valerio Ovchinnikov, Dmitry A. Passier, Robert Patrikakis, Margaret Pombo, Ana Pradhan-Bhatt, Swati Qin, Xian-Yang Rehli, Michael Rizzu, Patrizia Roy, S Division of Genomic Technologies RIKEN Center for Life Science Technologies Yokohama Kanagawa 230-0045 Japan RIKEN Omics Science Center Yokohama Kanagawa 230-0045 Japan Department of Medicine Karolinska Institutet Stockholm 14186 Sweden Karolinska University Hospital Center for Metabolism and Endocrinology Stockholm 14186 Sweden Scottish Centre for Regenerative Medicine University of Edinburgh 5 Little France Drive Edinburgh EH164UU United Kingdom Department of Dermatology and Allergy Charite University Medicine Berlin Charitéplatz 1 Berlin 10117 Germany Roslin Institute and Royal School of Veterinary Studies University of Edinburgh Edinburgh EH259RG United Kingdom Australian Infectious Diseases Research Centre University of Queensland St Lucia 4072 QLD Australia School of Chemistry and Molecular Biosciences University of Queensland St Lucia 4072 QLD Australia Bio-Rad Laboratories Pty Ltd Hercules 94547 CA United States University of Queensland Diamantina Institute University of Queensland Woolloongabba 4102 QLD Australia IRCCS Fondazione Santa Lucia Via del Fosso di Fiorano 64 Rome 00143 Italy Australian Institute for Bioengineering and Nanotechnology University of Queensland Brisbane St Lucia 4072 QLD Australia Division of Immunology Institute of Infectious Diseases and Molecular Medicine University of Cape Town Anzio Road Observatory 7925 South Africa Immunology of Infectious Diseases Faculty of Health Sciences South African Medical Research Council University of Cape Town Anzio Road 7925 South Africa International Centre for Genetic Engineering and Biotechnology Cape Town Component Anzio Road 7925 South Africa Hubrecht Institute Royal Netherlands Academy of Arts and Sciences Uppsalalaan 8 3584 Netherlands University Medical Centre Utrecht Postbus 85500 Utrecht 3508 Netherlands Genomics Cold Spring Harbor Laboratory Cold Spring Harbor New York 11797 NY United States Institute of Pharmaceutical Sciences ETH Zurich Vladi

In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.

关键词：

来源：评论

学校读者我要写书评

暂无评论

The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic

引用

四川生理科学杂志 2022年第7期44卷 1246-1246页

作者： Michael Worobey Department of Ecology and Evolutionary Biology University of Arizona Tucson AZ 85721 USA Department of Immunology and Microbiology The Scripps Research Institute La Jolla CA 92037 USA W. Harry Feinstone Department of Molecular Microbiology and Immunology Johns Hopkins Bloomberg School of Public Health Baltimore MD 21205 USA Bioinformatics and Systems Biology Graduate Program University of California San Diego La Jolla CA 92093 USA Department of Biomedical Informatics University of California San Diego La Jolla CA 92093 USA Department of Human Genetics University of Utah School of Medicine Salt Lake City UT 84112 USA Vaccine and Infectious Disease Organization University of Saskatchewan Saskatoon SK S7N 5E3 Canada Center for Global Health Science and Security Georgetown University Washington DC 20057 USA Department of Zoology University of Oxford Oxford OX1 3SZ UK Wildlife Conservation Research Unit Department of Zoology The Recanati-Kaplan Centre University of Oxford Oxford OX13 5QL UK Pandemic and Disaster Preparedness Centre Erasmus University Medical Center 3015 CE Rotterdam Netherlands Department of Viroscience Erasmus University Medical Center 3015 CE Rotterdam Netherlands Department of Biostatistics Fielding School of Public Health University of California Los Angeles Los Angeles CA 90095 USA Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA Department of Medicine University of California San Diego La Jolla CA 92093 USA Department of Microbiology Immunology and Transplantation Rega Institute for Medical Research KU Leuven 3000 Leuven Belgium Global Virus Network (GVN) Baltimore MD 21201 USA MRC-University of Glasgow Center for Virus Research Glasgow G61 1QH UK Tulane University School of Medicine Department of Microbiology and Immu

Understanding how severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)emerged in 2019 is critical to preventing zoonotic outbreaks before they become the next *** Huanan Seafood Wholesale Market in Wuhan,China,was identified as a likely source of cases in early reports but later this conclusion became *** show the earliest known COVID-19 cases from December 2019,including those without reported direct links,were geographically centered on this *** report that live SARS-CoV-2 susceptible mammals were sold at the market in late 2019 and,within the market,SARS-CoV-2-positive environmental samples were spatially associated with vendors selling live mammals.

关键词： Market likely Wuhan

来源：评论

学校读者我要写书评

暂无评论

Author Correction: A compendium of geochemical information from the Saanich Inlet water column

引用

Scientific data 2019年第1期6卷 1页

作者： Mónica Torres-Beltrán Alyse K Hawley David Capelle Elena Zaikova David A Walsh Andreas Mueller Melanie Scofield Chris Payne Larysa Pakhomova Sam Kheirandish Jan Finke Maya Bhatia Olena Shevchuk Esther A Gies Diane Fairley Céline Michiels Curtis A Suttle Frank Whitney Sean A Crowe Philippe D Tortell Steven J Hallam Department of Microbiology and Immunology University of British Columbia Vancouver British Columbia V6T 1Z3 Canada. Earth Ocean and Atmospheric Sciences University of British Columbia Vancouver British Columbia V6T 1Z4 Canada. Department of Biology Georgetown University Washington DC 20007 USA. Department of Biology Concordia University Montreal Quebec H4B 1R6 Canada. Department of Civil Engineering University of British Columbia Vancouver BC V6T 1Z4 Canada. Department of Botany University of British Columbia Vancouver British Columbia V6T 1Z4 Canada. Department of Fisheries and Oceans Canada Sidney British Columbia V9L 6V9 Canada. ECOSCOPE Training Program University of British Columbia Vancouver British Columbia V6T 1Z4 Canada. Peter Wall Institute for Advanced Studies University of British Columbia British Columbia V6T 1Z2 Canada. Department of Microbiology and Immunology University of British Columbia Vancouver British Columbia V6T 1Z3 Canada. shallam@mail.ubc.ca. ECOSCOPE Training Program University of British Columbia Vancouver British Columbia V6T 1Z4 Canada. shallam@mail.ubc.ca. Peter Wall Institute for Advanced Studies University of British Columbia British Columbia V6T 1Z2 Canada. shallam@mail.ubc.ca. Genome Science and Technology Program University of British Columbia Vancouver BC V6T 1Z4 Canada. shallam@mail.ubc.ca. Graduate Program in Bioinformatics University of British Columbia Vancouver British Columbia V6T 1Z4 Canada. shallam@mail.ubc.ca.

In Table 3 of this Data Descriptor the units of Mean_N2O and Mean_CH4 are incorrectly stated as "Nanomolar (μM)". This should instead read "Nanomolar (nM)".

关键词：

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：