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30th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBS'08

作者： Seung, Min Lee Ko, Keun Kim Kwang, Suk Park Interdisciplinary Program of Bioengineering Seoul National University Graduate School Korea Republic of Interdisciplinary Program in Medical and Biological Engineering Seoul National University Graduate School Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)9781424418152

Capacitive coupled Electrocardiography (ECG) is introduced as non-invasive measurement technology for ubiquitous health care and appliance are spread out widely. Although it has many merits, however, capacitive coupled ECG is very weak for motion artifacts for its non-skin-contact property. There are many studies for artifact problems which treats all artifact signals below 0.8Hz. In our capacitive coupled ECG measurement system, artifacts exist not only below 0.8Hz but also over than 10Hz. Therefore, artifact noise removal algorithm using wavelet method is tested to reject artifact-wandered signal from measured signals. It is observed that using power calculation each decimation step, artifact-wandered signal is removed as low frequency artifacts as high frequency artifacts. Although some original ECG signal is removed with artifact signal, we could level the signal quality for long term measure which shows the best quality ECG signals as we can get. © 2008 IEEE.

关键词： Electrocardiography

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System for unconstrained ECG measurement on a toilet seat using capacitive coupled electrodes : The efficacy and practicality

System for unconstrained ECG measurement on a toilet seat us...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Hyun Jae Baek Jung Soo Kim Ko Keun Kim Kwang Suk Park Interdisciplinary Program of Bioengineering Seoul National University Graduate School Republic of Korea Interdisciplinary Program in Medical and Biological Engineering Seoul National University Graduate School Republic of Korea Department of Biomedical Engineering Seoul National University Republic of Korea

Home healthcare is a common matter of concern to modern people. For the successful home healthcare, unconstrained bio-signal monitoring is important. Previously, unconstrained lavatory typed ECG measurement system was developed. It is enough to measure subject's ECG signal non-intrusively, but not practical because of moist environment of toilet. In this study, capacitive coupled electrode was employed for overcome above disadvantages. ECG was obtained by capacitive coupled electrode and compared with ECGs obtained from conventional Ag/AgCl electrode. Possible motion artifacts were investigated. Experimental results showed that toilet based capacitive coupled ECG signal was measured successfully.

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Classification of Parkinson gait and normal gait using Spatial-Temporal Image of Plantar pressure

Classification of Parkinson gait and normal gait using Spati...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Hyo-Seon Jeon Jonghee Han Won-Jin Yi BeomSeok Jeon Kwang Suk Park Interdisciplinary Program in Medical and Biological Engineering Graduate School Seoul National University South Korea Department of Oral and Maxillofacial Radiology College College of Dentistry Seoul National University South Korea Department of Neurology Seoul National University South Korea Department of Biomedical Engineering College of Medicine Seoul National University South Korea

The purpose of this paper is the classification of Spatial-Temporal Image of Plantar pressure (STIP) among normal step and the patients step of Parkinson disease. For this, we created a new image data, STIP, that have information of the change of plantar pressure during heel to toe motion (i.e., contain spatial and temporal information for plantar pressure). To get STIP, the walking of 21 patients with Parkinson disease and 17 age-matched healthy subjects were recorded and analyzed using in-shoe dynamic pressure measuring system with comfort walking. For feature extraction of gait, we applied Principal component analysis (PCA) to STIP and calculated weights of STIP on each principal components. Then, we build hard margin Support Vector Machine (SVM) classifier for gait recognition and test of generalization performance using normalized weights on PCs of STIP. SVM result indicated an overall accuracy of 91.73% by the RBF(Radial Basis Function) kernel function. These results demonstrate considerable potential in applying SVMs in gait classification for many applications.

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Implementation of the relay server for the Ubiquitous Integrated Biotelemetry System for Emergency Care (UIBSEC) based on 3.5G HSDPA technology

Implementation of the relay server for the Ubiquitous Integr...

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29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Min, Yang Jung Jaemin, Kang Il, Hyung Shin Yoonseo, Koo Gil, Joon Suh Hee, Chan Kim Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Emergency Medicine Seoul National University Seoul Korea Republic of Department of Biomedical Engineering Institute of Medical and Biological Engineering Seoul National University Seoul Korea Republic of

ISBN: (纸本)1424407885

When an emergent case occurs, to give proper and immediate emergency treatment to a patient is as important as to transfer him or her to the hospital as early as possible. For this circumstance where first aid usually happens in an ambulance, we developed the Ubiquitous Integrated Biotelemetry System for Emergency Care (UIBSEC) based on wireless 3.5G HSDPA module in order to provide more proper and active medical care to a patient. For this system we performed experimental tests on the HSDPA module to measure practical performance values with respect to throughput and RTT (round-trip-time) and compared the result with the theoretical specifications. In the course of developing this system we created the C#-based Network Solution Library (NSL) which helps drastically reducing the overhead. We applied this library to components of the UIBSEC - two kinds of clients and one central server - and confirmed that it works smoothly in wireless networks and it is useful in the future development process of network applications. © 2007 IEEE.

关键词： Servers

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Noninvasive heart rate variability analysis using loadcell-installed bed during sleep

Noninvasive heart rate variability analysis using loadcell-i...

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29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Chung, Gih Sung Choi, Byoung Hoon Jeong, Do-Un Park, Kwang Suk Interdisciplinary Program in Medical and Biological Engineering Seoul National University Graduate School Korea Republic of Dept. of Neuropsychiatry College of Medicine and Hospital Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)1424407885

Polysomnography is the standard method to score the sleep stages or to determine the quality of sleep. During all night examination, subjects must attach complicate and numerous electrodes on their body to acquire the biosignals. They can influence participants' sleep stage transition or sleep pattern, and the method seems intricate. In many researches, it is reported that autonomic nervous system (ANS) is varying with sleep stage transition and heart rate variability (HRV) is one of the indices which reflects the changes of autonomic nervous system. In this point of view, we can estimate the sleep quality by observing the HRV variation. In this study, to analyze the heart rate variability, we introduce a new system that can detect the heart beats of subjects during sleep by using bed installed load-cell sensors. The pressure to the sensor changes with the pulsation of the heart and we consider it as ballistocardiogram, the physical heart beat signal. To validate our system, we adopted this system for the 4 subjects with the polysomnography. The results show the LF/HF ratio of the heart rate, one of the reflection parameters of ANS, acquired from the system for each sleep stage. To validate the results, the HRV from electrocardiogram using Ag-AgCl electrodes will be compared. © 2007 IEEE.

关键词： biomedical engineering

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Segmentation of solid nodules in ultrasonographic breast image based on wavelet transform

Segmentation of solid nodules in ultrasonographic breast ima...

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29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Park, Sangyun Kong, Hyoun-Joong Moon, Woo Kyoung Kim, Hee Chan Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Radiology Seoul National University Seoul 110-744 Korea Republic of Department of Biomedical Engineering College of Medicine and Institute of Medical and Biological Engineering Seoul National University Seoul Korea Republic of

ISBN: (纸本)1424407885

An accurate segmentation of solid nodules in ultrasonographic (US) breast image is presented. 1-level 2-dimensional Discrete Wavelet Transform (DWT) is used to create features reflecting the texture information of the original image. Using these features, the texture classification is achieved. Finally, solid nodule region is segmented from the classified texture region. Proper threshold for texture classification is automatically decided. Empirically acquired information about the relationship between the texture characteristic of the original image and the optimal threshold is examined and used. Presented algorithm is applied to 284 malignant solid nodules and 300 benign solid nodules and the resulting images are presented. © 2007 IEEE.

关键词： Ultrasonography

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Contributors to the Lab on a Chip cell and tissue engineering in microsystems special issue

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Lab on a Chip 2007年第6期7卷 667-671页

作者： Bhatia, Sangeeta N. Chen, Christoper Bashir, Rashid Beebe, David J. Desai, Tejal Gottwald, Eric Khademhosseini, Ali Langer, Robert S. Piel, Matthieu Takayama, Shuichi Thorsen, Todd Tien, Joe Voldman, Joel Vunjak-Novakovic, Gordana Wu, Mingming Yu, Hanry Massachusetts Institute of Technology Harvard-MIT Division of Health Sciences and Technology Department of Electrical Engineering and Computer Science United States Laboratory for Multiscale Regenerative Technologies United States Department of Innovation University of Pennsylvania Department of Bioengineering United States Cell Biology and Physiology Program Cell Growth and Cancer Program Tissue Microfabrication Laboratory Department of Electrical and Computer Engineering and Biomedical Engineering Purdue University United States Department of Electronics University of Glasgow United Kingdom Department of Physiology and Bioengineering University of California San Francisco CA United States California Institute for Quantitative Biomedical Research UCSF/UC Berkeley Graduate Group in Bioengineering United States Laboratory of Therapeutic Micro and Nanotechnology Institute for Biological Interfaces Germany 3D-Cell Culture Techniques Group Institute for Biological Interfaces Germany Department of Medicine and Health Sciences and Technology Massachusetts Institute of Technology (MIT) United States Institut Curie UMR 144 IC/CNRS France Biomedical Engineering Department University of Michigan United States Department of Biomedical Engineering Macromolecular Science and Engineering Program United States Sibley School of Mechanical and Aerospace Engineering School of Chemical and Molecular Engineering Cornell University United States National University of Singapore Singapore Institute of Bioengineering and Nanotechnology A STAR Singapore

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The relationship between HRV parameters and stressful driving situation in the real road

The relationship between HRV parameters and stressful drivin...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Haet Bit Lee Jung Soo Kim Yun Seong Kim Hyun Jae Baek Myung Suk Ryu Kwang Suk Park Seoul National University South Korea Interdisciplinary Program in Medical and Biological Engineering Graduate School Republic of Korea Advanced Biometric Research Center Republic of Korea Department of Biomedical Engineering Seoul National University Republic of Korea

The aim of this paper is to find a relation between HRV parameters of ECG and stressful driving situation in the real road through various tests. First, we gave a stress to the subject by increasing the driving speed using driving simulator in the laboratory. Second, the subject drove the vehicle on the real road. Through let him drove in the busy narrow street, we evoked stress. ECG and PPG signal was recorded from steering wheel and back cushion each unconsciously. The driving experiment with simulator was not suitable to reproduce actual traffic condition because the adaptation was occurred. On the other hand, in real driving test, the results show that the heart rate is increase, and SDNN, RMSSD, pNN50 were decreased. The heart rate is the strongest indicator and other parameters tend to be changed depend on a personal. The blood pressure had no significant changes. Our results show the good possibility of that the time parameters of the HRV could be used as an instantaneous stress indicator.

关键词： Heart rate variability Stress Electrocardiography Testing Heart rate Laboratories Road vehicles Wheels Traffic control Blood pressure

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Blank slate engineering at Florida Gulf Coast University - Innovative and multidisciplinary from the ground up

Blank slate engineering at Florida Gulf Coast University - I...

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113th Annual ASEE Conference and Exposition, 2006

作者： Blanchard, Susan Egiebor, Nosa Sweeney, James Zidek, Lisa Sechrist, Chalmers Hulbert, Sam Osborn, James O'Neill, Robert Florida Gulf Coast University United States FGCU School of Engineering Institute of Electrical and Electronics Engineers Biomedical Engineering Society American Institute for Medical and Biological Engineering United Kingdom Department of Environmental and Civil Engineering Arizona State University United States Department of Bioengineering Department of Bioengineering Arizona State University United States Flinn Foundation Funded Multi- and Interdisciplinary Graduate Training Program in Bioengineering Milwaukee School of Engineering United States Graduate Programs Industrial Engineering Program Department of Electrical and Computer Engineering Department of Engineering University of Illinois Urbana-Champaign United States Institute of Electrical and Electronics Engineers Rose-Hulman Institute for Technology School of Engineering FGCU School of Engineering's Advisory Board Roger Williams University United States Department of Civil Engineering Department of Engineering Roger Williams University United States

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Self-forming lateral apertures in silicon microchannels for patch clamping

Self-forming lateral apertures in silicon microchannels for ...

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9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005

作者： Yobas, Levent Zhao, Liping Zhu, Jia Kumar, Rajnish Sharma Nagarajan, Ranganathan Liw, Saxon Hui, Wing Cheong Lim, Tit-Meng Sheu, Fwu-Shan Singapore Singapore Graduate Program in Biomedical Engineering National University of Singapore Singapore Singapore School of Electrical and Electronic Engineering Nanyang Technological University Singapore Singapore Department of Biological Sciences National University of Singapore Singapore Singapore

ISBN: (纸本)0974361119

A lateral aperture with a round profile ideal for patch clamping is created by isotropic dry etching through a silicon micropartition between two microchannels. A special package design is introduced to establish an air-tight fluidic and electrical interface between the chip and the pipette holder of a commercial patch clamp amplifier. The electrical resistance across the lateral aperture with a diameter of 7.5μm ranges from 0.5MΩ to 0.7MΩ. Cells in suspension injected into the microchannel can be actively manipulated towards the lateral patch aperture by microfluidic flow control. Nearby cells can be successfully trapped via suction applied through the aperture. Copyright © 2005 by the Transducer Research Foundation, Inc.

关键词： Microfluidics

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