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The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic

四川生理科学杂志 2022年第7期44卷 1246-1246页

作者： Michael Worobey Department of Ecology and Evolutionary Biology University of Arizona Tucson AZ 85721 USA Department of Immunology and Microbiology The Scripps Research Institute La Jolla CA 92037 USA W. Harry Feinstone Department of Molecular Microbiology and Immunology Johns Hopkins Bloomberg School of Public Health Baltimore MD 21205 USA Bioinformatics and Systems Biology Graduate Program University of California San Diego La Jolla CA 92093 USA Department of Biomedical Informatics University of California San Diego La Jolla CA 92093 USA Department of Human Genetics University of Utah School of Medicine Salt Lake City UT 84112 USA Vaccine and Infectious Disease Organization University of Saskatchewan Saskatoon SK S7N 5E3 Canada Center for Global Health Science and Security Georgetown University Washington DC 20057 USA Department of Zoology University of Oxford Oxford OX1 3SZ UK Wildlife Conservation Research Unit Department of Zoology The Recanati-Kaplan Centre University of Oxford Oxford OX13 5QL UK Pandemic and Disaster Preparedness Centre Erasmus University Medical Center 3015 CE Rotterdam Netherlands Department of Viroscience Erasmus University Medical Center 3015 CE Rotterdam Netherlands Department of Biostatistics Fielding School of Public Health University of California Los Angeles Los Angeles CA 90095 USA Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA 90095 USA Department of Medicine University of California San Diego La Jolla CA 92093 USA Department of Microbiology Immunology and Transplantation Rega Institute for Medical Research KU Leuven 3000 Leuven Belgium Global Virus Network (GVN) Baltimore MD 21201 USA MRC-University of Glasgow Center for Virus Research Glasgow G61 1QH UK Tulane University School of Medicine Department of Microbiology and Immu

Understanding how severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)emerged in 2019 is critical to preventing zoonotic outbreaks before they become the next *** Huanan Seafood Wholesale Market in Wuhan,China,was identified as a likely source of cases in early reports but later this conclusion became *** show the earliest known COVID-19 cases from December 2019,including those without reported direct links,were geographically centered on this *** report that live SARS-CoV-2 susceptible mammals were sold at the market in late 2019 and,within the market,SARS-CoV-2-positive environmental samples were spatially associated with vendors selling live mammals.

关键词： Market likely Wuhan

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Applying the MVC EA-IRPM to reporting-guidelines in medicine: A strategy that is a web system 4

Applying the MVC EA-IRPM to reporting-guidelines in medicine...

引用

4th IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2017

作者： Letouze, Patrick De Souza, J.I.M. Silva, Valeria Martins Climaco, Glaubos Chagas, F.B. Ishihara, Joao Y. Graduate Program of Computational Modeling of Systems Universidade Federal Do Tocantins Quadra 109 Norte Avenida NS-15 Palmas77001-090 Brazil Graduate Program of Systems' Engineering and Computation - PESC Universidade Federal Do Rio de Janeiro Rio de Janeiro Brazil Department of Informatics at the Universidade Federal Do Maranh/ Ao - UFMA Brazil Faculty of Computer Science Faculdade Pitagoras Imperatriz Imperatriz Brazil Faculty of Electrical Engineering Universidade de Brasília Brasília Brazil

ISBN: (纸本)9781509041794

Reporting-Guidelines in Medicine play an important role in promoting the quality of reports in health-related research. For instance, a poorly reported research may induce misinterpretation and inappropriate clinical settings. Basically, three major issues regarding Reporting-Guidelines in Medicine has to be addressed: (1) the existence of lots of reporting guidelines covering a broad spectrum of medical research increases the difficulties when reporting a medical research because it may not be clear which guidelines are applicable, or if all related guidelines are considered;(2) most guideline developers have not described how their guidance was developed, consequently tracking guidelines and features for evaluation, or even for correcting, may be not possible;(3) few guideline developers have evaluated the effectiveness of their guidance, then the real value that the guideline brings to reporting the research is not assured. Hence, we propose a solution to these three issues based on the Model-View-Controller Evolutionary Acquisition Interdisciplinary Research Project Management (MVC EA-IRPM) that is simultaneously a strategy and a web system for the development and management of reporting guidelines. © 2017 IEEE.

关键词： Clinical research

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Publisher Correction: Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells

Communications biology

引用

Communications biology 2020年第1期3卷 251页

作者： Ki-Hyeon Seong Nhung Hong Ly Yuki Katou Naoko Yokota Ryuichiro Nakato Shinnosuke Murakami Akiyoshi Hirayama Shinji Fukuda Siu Kang Tomoyoshi Soga Katsuhiko Shirahige Shunsuke Ishii RIKEN Cluster for Pioneering Research Tsukuba Ibaraki Japan. ki-hyeon.seong@riken.jp. PRESTO Japan Science and Technology Agency Kawaguchi Japan. ki-hyeon.seong@riken.jp. RIKEN Cluster for Pioneering Research Tsukuba Ibaraki Japan. Laboratory of Genome Structure and Function Institute for Quantitative Biosciences University of Tokyo Tokyo Japan. Laboratory of Computational Genomics Institute for Quantitative Biosciences University of Tokyo Tokyo Japan. Institute for Advanced Biosciences Keio University Tsuruoka Yamagata Japan. Systems Biology Program Graduate School of Media and Governance Keio University Fujisawa Kanagawa Japan. PRESTO Japan Science and Technology Agency Kawaguchi Japan. Transborder Medical Research Center University of Tsukuba Tsukuba Ibaraki Japan. Department of Bio-Systems Engineering Graduate School of Science and Engineering Yamagata University Yonezawa Yamagata Japan. RIKEN Cluster for Pioneering Research Tsukuba Ibaraki Japan. sishii@riken.jp.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Orbital migration of interacting stellar mass black holes in disks around supermassive black holes II. Spins and incoming objects

arXiv

引用

arXiv 2020年

作者： Secunda, Amy Bellovary, Jillian Low, Mordecai-Mark Mac Saavik Ford, K.E. McKernan, Barry Leigh, Nathan W.C. Lyra, Wladimir Sándor, Zsolt Adorno, Jose I. Department of Astrophysics American Museum of Natural History Central Park West at 79th Street New YorkNY10024 United States Department of Astrophysical Sciences Princeton University Peyton Hall PrincetonNJ08544 United States Department of Physics Queensborough Community College BaysideNY11364 United States Physics Program Graduate Center City University of New York New YorkNY10016 United States Center for Computational Astrophysics Flatiron Institute New YorkNY10010 United States Department of Science Borough of Manhattan Community College City University of New York New YorkNY10007 United States Departamento de Astronomía Facultad de Ciencias Físicas y Matemáticas Universidad de Concepción Concepción Chile Department of Astronomy New Mexico State University Las CrucesNM88003 United States Department of Astronomy Eötvös Loránd University Pázmány Péter sétány 1/A BudapestH-1117 Hungary Konkoly Observatory Research Centre for Astronomy and Earth Sciences BudapestH-1121 Hungary Department of Physics Queens College City University of New York QueensNY11367 United States

The mass, rate, and spins of merging stellar-mass binary black holes (BBHs) detected by aLIGO and Advanced Virgo provide challenges to traditional BBH formation and merger scenarios. An active galactic nucleus (AGN) disk provides a promising additional merger channel, because of the powerful influence of the gas that drives orbital evolution, makes encounters dissipative, and leads to migration. Previous work showed that stellar mass black holes (sBHs) in an AGN disk migrate to regions of the disk, known as migration traps, where positive and negative gas torques cancel out, leading to frequent BBH formation. Here we build on that work by simulating the evolution of additional sBHs that enter the inner disk by either migration or inclination reduction. We also examine whether the BBHs formed in our models have retrograde or prograde orbits around their centers of mass with respect to the disk, determining the orientation, relative to the disk, of the spin of the merged BBHs. We find that orbiters entering the inner disk form BBHs, that are commonly asymmetric in mass, with sBHs on resonant orbits near the migration trap. When these black holes reach & 80 M, they form BBHs with sBHs in the migration trap, which over 10 Myr reach ∼ 1000 M. We also find that 68% of the BBHs in our simulation orbit in the retrograde direction, which implies our merger channel could easily produce the low values of the dimensionless aligned spin, χeff, observed in a majority of BBH mergers detected thus far. Copyright © 2020, The Authors. All rights reserved.

关键词： Stars

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Ten simple rules for reproducible research in jupyter notebooks

arXiv

引用

arXiv 2018年

作者： Rule, Adam Birmingham, Amanda Zuniga, Cristal Altintas, Ilkay Huang, Shih-Cheng Knight, Rob Moshiri, Niema Nguyen, Mai H. Rosenthal, Sara Brin Pérez, Fernando Rose, Peter W. Design Lab UC San Diego San DiegoCA United States Center for Computational Biology and Bioinformatics UC San Diego San DiegoCA United States Department of Pediatrics UC San Diego San DiegoCA United States Data Science Hub San Diego Supercomputer Center UC San Diego San DiegoCA United States Departments of Bioengineering and Computer Science and Engineering Center for Microbiome Innovation UC San Diego San DiegoCA United States Bioinformatics and Systems Biology Graduate Program UC San Diego San DiegoCA United States Department of Statistics Berkeley Institute for Data Science UC Berkeley Lawrence Berkeley National Laboratory BerkeleyCA United States Biomedical Informatics Graduate Program Stanford University StanfordCA United States

Reproducibility of computational studies is a hallmark of scientific methodology. It enables researchers to build with confidence on the methods and findings of others, reuse and extend computational pipelines, and thereby drive scientific progress. Since many experimental studies rely on computational analyses, biologists need guidance on how to set up and document reproducible data analyses or simulations. In this paper, we address several questions about reproducibility. For example, what are the technical and non-technical barriers to reproducible computational studies? What opportunities and challenges do computational notebooks offer to overcome some of these barriers? What tools are available and how can they be used effectively? We have developed a set of rules to serve as a guide to scientists with a specific focus on computational notebook systems, such as Jupyter Notebooks, which have become a tool of choice for many applications. Notebooks combine detailed workflows with narrative text and visualization of results. Combined with software repositories and open source licensing, notebooks are powerful tools for transparent, collaborative, reproducible, and reusable data analyses. Copyright © 2018, The Authors. All rights reserved.

关键词： Digital storage

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A broadband thermal emission spectrum of the ultra-hot Jupiter WASP-18b

arXiv

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arXiv 2023年

作者： Coulombe, Louis-Philippe Benneke, Björn Challener, Ryan Piette, Anjali A.A. Wiser, Lindsey S. Mansfield, Megan MacDonald, Ryan J. Beltz, Hayley Feinstein, Adina D. Radica, Michael Savel, Arjun B. Dos Santos, Leonardo A. Bean, Jacob L. Parmentier, Vivien Wong, Ian Rauscher, Emily Komacek, Thaddeus D. Kempton, Eliza M.-R. Tan, Xianyu Hammond, Mark Lewis, Neil T. Line, Michael R. Lee, Elspeth K.H. Shivkumar, Hinna Crossfield, Ian J.M. Nixon, Matthew C. Rackham, Benjamin V. Wakeford, Hannah R. Welbanks, Luis Zhang, Xi Batalha, Natalie M. Berta-Thompson, Zachory K. Changeat, Quentin Désert, Jean-Michel Espinoza, Néstor Goyal, Jayesh M. Harrington, Joseph Knutson, Heather A. Kreidberg, Laura López-Morales, Mercedes Shporer, Avi Sing, David K. Stevenson, Kevin B. Aggarwal, Keshav Ahrer, Eva-Maria Alam, Munazza K. Bell, Taylor J. Blecic, Jasmina Caceres, Claudio Carter, Aarynn L. Casewell, Sarah L. Crouzet, Nicolas Cubillos, Patricio E. Decin, Leen Fortney, Jonathan J. Gibson, Neale P. Heng, Kevin Henning, Thomas Iro, Nicolas Kendrew, Sarah Lagage, Pierre-Olivier Leconte, Jérémy Lendl, Monika Lothringer, Joshua D. Mancini, Luigi Mikal-Evans, Thomas Molaverdikhani, Karan Nikolov, Nikolay K. Ohno, Kazumasa Palle, Enric Piaulet, Caroline Redfield, Seth Roy, Pierre-Alexis Tsai, Shang-Min Venot, Olivia Wheatley, Peter J. Department of Physics Trottier Institute for Research on Exoplanets Université de Montréal MontréalQC Canada Department of Astronomy University of Michigan Ann ArborMI United States Earth and Planets Laboratory Carnegie Institution for Science WashingtonDC United States School of Earth and Space Exploration Arizona State University TempeAZ United States Steward Observatory University of Arizona TucsonAZ United States NHFP Sagan Fellow United States Department of Astronomy Carl Sagan Institute Cornell University NY United States Department of Astronomy and Astrophysics University of Chicago ChicagoIL United States NSF Graduate Research Fellow United States Department of Astronomy University of Maryland College ParkMD United States Center for Computational Astrophysics Flatiron Institute New YorkNY United States Space Telescope Science Institute BaltimoreMD United States Université Côte d’Azur Observatoire de la Côte d’Azur CNRS Laboratoire Lagrange France NASA Goddard Space Flight Center GreenbeltMD United States NASA Postdoctoral Program Fellow United States Tsung-Dao Lee Institute Shanghai Jiao Tong University Shanghai China School of Physics and Astronomy Shanghai Jiao Tong University Shanghai China Atmospheric Oceanic and Planetary Physics Department of Physics University of Oxford Oxford United Kingdom Department of Mathematics and Statistics Faculty of Environment Science and Economy University of Exeter Exeter United Kingdom Center for Space and Habitability University of Bern Bern Switzerland Anton Pannekoek Institute for Astronomy University of Amsterdam Amsterdam Netherlands Department of Physics & Astronomy University of Kansas LawrenceKS United States Department of Earth Atmospheric and Planetary Sciences Massachusetts Institute of Technology CambridgeMA United States Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA United States 51 Pegasi b Fellow France School of

Close-in giant exoplanets with temperatures greater than 2,000 K ("ultra-hot Jupiters") have been the subject of extensive efforts to determine their atmospheric properties using thermal emission measurements from the Hubble and Spitzer Space Telescopes1;2;3. However, previous studies have yielded inconsistent results because the small sizes of the spectral features and the limited information content of the data resulted in high sensitivity to the varying assumptions made in the treatment of instrument systematics and the atmospheric retrieval analysis3;4;5;6;7;8;9;10;11;12. Here we present a dayside thermal emission spectrum of the ultrahot Jupiter WASP-18b obtained with the NIRISS13 instrument on JWST. The data span 0.85 to 2.85 µm in wavelength at an average resolving power of 400 and exhibit minimal systematics. The spectrum shows three water emission features (at >6σ confidence) and evidence for optical opacity, possibly due to H−, TiO, and VO (combined significance of 3.8σ). Models that fit the data require a thermal inversion, molecular dissociation as predicted by chemical equilibrium, a solar heavy element abundance ("metallicity", M/H = 1.03+1.11−0.51 × solar), and a carbon-to-oxygen (C/O) ratio less than unity. The data also yield a dayside brightness temperature map, which shows a peak in temperature near the sub-stellar point that decreases steeply and symmetrically with longitude toward the terminators. © 2023, CC BY.

关键词： Molecular oxygen

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Autonomous Exploration Guided by Optimisation Metaheuristic

Autonomous Exploration Guided by Optimisation Metaheuristic

引用

International Conference on Control, Automation, Robotics and Vision

作者： Raphael Gomes Santos Edison Pignaton de Freitas Sen Cheng Paulo Rogerio de Almeida Ribeiro Alexandre Cesar Muniz de Oliveira Federal University of Maranhão São Luís MA Brazil Graduate Program on Computer Science Federal University of Rio Grande do Sul Porto Alegre Brazil Computational Neuroscience Ruhr University Bochum Bochum Germany Department of Computer Engineering Federal University of Maranhão São Luís Maranhão Department of Informatics Federal University of Maranhão São Luís Maranhão

Autonomous exploration aims to develop mechanisms that enable a robot to navigate through an unknown environment, seeking to collect information that is relevant to its objective, with minimal or no human intervention. This article presents an autonomous exploration strategy based on a multimodal continuous utility function and optimization metaheuristic. The problem of autonomous exploration of mobile robots is formulated as an optimization problem, providing data for a Firefly-based algorithm that is able to search for points in the solution space, representing cells on the map being constructed, that best meet the exploration objectives. Simulations in a Robot Operating System environment showed that the proposed approach is able to guide robot through good trajectories, leading to full mapping, without any human intervention.

关键词： Linear programming Optimization Heuristic algorithms Robot kinematics Navigation Mobile robots

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Ultrafast asymmetric Rosen-Zener-like coherent phonon responses observed in silicon

arXiv

引用

arXiv 2018年

作者： Watanabe, Yohei Hino, Ken-Ichi Maeshima, Nobuya Petek, Hrvoje Hase, Muneaki Doctoral Program in Materials Science Graduate School of Pure and Applied Sciences University of Tsukuba Tsukuba Ibaraki305-8573 Japan Division of Materials Science Faculty of Pure and Applied Sciences University of Tsukuba Tsukuba305-8573 Japan Center for Computational Sciences University of Tsukuba Tsukuba305-8577 Japan Department of Physics and Astronomy Pittsburgh Quantum Institute University of Pittsburgh PittsburghPA15260 United States Division of Applied Physics Faculty of Pure and Applied Sciences University of Tsukuba Tsukuba305-8573 Japan

We investigate the spectral profiles of time signals attributed to coherent phonon generation in an undoped Si crystal. Here, the retarded longitudinal-optical (LO) phonon Green function relevant to the temporal variance of induced charge density of ionic cores is calculated by employing the polaronic quasiparticle model developed by the authors [Y. Watanabe et al., Phys. Rev. B 95, 014301 (2017);ibid., 96, 125204 (2017)]. The spectral asymmetry is revealed in the frequency domain of the signals under the condition that an LO phonon mode stays almost energetically resonant with a plasmon mode in the early time region;this lasts for approximately 100 fs immediately after the irradiation of an ultrashort pump-laser pulse. It is understood that based on the adiabatic picture in time, this asymmetry is caused by the Rosen-Zener coupling between both modes. The associated experimental results are obtained by measuring time-dependent electro-optic reflectivity signals, and it is proved that these are in harmony with the calculated ones. The spectra become more symmetric, as the photoexcited carrier density further changes from that meeting the above condition to higher and lower sides of carrier densities. Moreover, the effect of optical nutation of carrier density on the CP signals is addressed, and the present results are compared with the asymmetry caused by transient Fano resonance, and the spectral profiles observed in a GaAs crystal in the text. Copyright © 2018, The Authors. All rights reserved.

关键词： Carrier concentration

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TOI-2015 b: a sub-Neptune in strong gravitational interaction with an outer non-transiting planet

arXiv

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arXiv 2025年

作者： Barkaoui, K. Korth, J. Gaidos, E. Agol, E. Parviainen, H. Pozuelos, F.J. Palle, E. Narita, N. Grimm, S. Brady, M. Bean, J.L. Morello, G. Rackham, B.V. Burgasser, A.J. Van Grootel, V. Rojas-Ayala, B. Seifahrt, A. Marfil, E. Passegger, V.M. Stalport, M. Gillon, M. Collins, K.A. Shporer, A. Giacalone, S. Yalçınkaya, S. Ducrot, E. Timmermans, M. Triaud, A.H.M.J. de Wit, J. Soubkiou, A. Watkins, C.N. Aganze, C. Alonso, R. Amado, P.J. Basant, R. Baştürk, Ö. Benkhaldoun, Z. Burdanov, A. Calatayud-Borras, Y. Chouqar, J. Conti, D.M. Collins, K.I. Davoudi, F. Delrez, L. Dressing, C.D. de Leon, J. Dévora-Pajares, M. Demory, B.O. Dransfield, G. Esparza-Borges, E. Fernández-Rodriguez, G. Fukuda, I. Fukui, A. Gallardo, P.P.M. Garcia, L. Garcia, N.A. Ghachoui, M. Geraldía-González, S. Chew, Y. Gómez Maqueo González-Rodríguez, J. Günther, M.N. Hayashi, Y. Horne, K. Hooton, M.J. Hsu, C.C. Ikuta, K. Isogai, K. Jehin, E. Jenkins, J.M. Kawauchi, K. Kagetani, T. Kawai, Y. Kasper, D. Kielkopf, J.F. Klagyivik, P. Lacedelli, G. Latham, D.W. Libotte, F. Luque, R. Livingston, J.H. Mancini, L. Massey, B. Mori, M. Torres, S. Muñoz Murgas, F. Niraula, P. Orell-Miquel, J. Rapetti, David Rebolo-López, R. Ricker, G. Papini, R. Pedersen, P.P. Peláez-Torres, A. Pérez-Prieto, J.A. Poultourtzidis, E. Rodriguez, P.M. Queloz, D. Savel, A.B. Schanche, N. Sánchez-Benavente, M. Sibbald, L. Sefako, R. Sohy, S. Sota, A. Schwarz, R.P. Seager, S. Sebastian, D. Southworth, J. Stangret, M. Stefánsson, G. Stürmer, J. Srdoc, G. Thompson, S.J. Terada, Y. Vanderspek, R. Wang, G. Watanabe, N. Wilkin, F.P. Winn, J. Wells, R.D. Ziegler, C. Zúñiga-Fernández, S. Astrobiology Research Unit Université de Liège Allée du 6 Août 19C LiègeB-4000 Belgium Department of Earth Atmospheric and Planetary Science Massachusetts Institute of Technology 77 Massachusetts Avenue CambridgeMA02139 United States Calle Vía Láctea s/n Tenerife La Laguna38200 Spain Lund Observatory Division of Astrophysics Department of Physics Lund University Box 118 Lund22100 Sweden Department of Earth Sciences University of Hawaii at Manoa 1680 East-West Rd HonoluluHI96822 United States Institute for Astrophysics University of Vienna Türkenschanzstrasse 17 ViennaA-1180 Austria Department of Astronomy Astrobiology Program University of Washington Box 351580 SeattleWA98195 United States NExSS Virtual Planetary Laboratory University of Washington Box 351580 SeattleWA98195 United States Tenerife La LagunaE-38206 Spain Glorieta de la Astronomía s/n Granada18008 Spain INAF- Palermo Astronomical Observatory Piazza del Parlamento 1 Palermo90134 Italy Komaba Institute for Science The University of Tokyo 3-8-1 Komaba Meguro Tokyo153-8902 Japan Astrobiology Center 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Research Institute for Advanced Computer Science Universities Space Research Association WashingtonDC20024 United States Institute for Particle Physics and Astrophysics ETH Zürich OttoStern-Weg 5 Zürich8093 Switzerland Department of Astrophysics University of Zürich Winterthurerstrasse 190 Zürich8057 Switzerland Department of Astronomy & Astrophysics University of Chicago ChicagoIL United States NHFP Sagan Fellow United States Department of Physics Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States Institute Université de Liège Allée du 6 Août 19C LiègeB-4000 Belgium Instituto de Alta Investigación Universidad de Tarapacá Casilla 7D Arica Chile Gemini Observatory NSF NOIRLab 670 N. A’ohoku Place HiloHI96720 United States Departamento de

TOI-2015 is a known exoplanetary system around an M4 dwarf star, consisting of a transiting sub-Neptune planet in a 3.35-day orbital period, TOI-2015 b, accompanied by a non-transiting companion, TOI-2015 c. High-precision radial velocity measurements were taken with the MAROON-X spectrograph, and high-precision photometric data were collected, primarily using the SPECULOOS, MUSCAT, TRAPPIST and LCOGT networks. We collected 63 transit light curves and 49 different transit epochs for TOI-2015 b. We re-characterize the target star by combining optical spectra obtained by the MAROON-X, Shane/KAST and IRTF/SpeX spectrographs, Bayesian Model Averaging (BMA) and Spectral Energy Distribution (SED) analysis. The TOI-2015 host star is a K = 10.3 mag M4-type dwarf with a sub-solar metallicity of [e/H]= −0.31 ± 0.16, and an effective temperature of Teff ≈ 3200 K. Our photodynamical analysis of the system strongly favors the 5:3 mean motion resonance and in this scenario the planet b (TOI-2015 b) has an orbital period of Pb = 3.34 days, a mass of Mp = 9.02+0.32−0.36 M⊗, a radius of Rp = 3.309+0.013−0.11 R⊗, resulting in a density of ρp = 0.25±0.01 ρ⊗ = 1.40±0.06 g cm−3, indicative of a Neptune-like composition. Its transits exhibit large (> 1 hr) timing variations indicative of an outer perturber in the system. We performed a global analysis of the high-resolution radial-velocity measurements, the photometric data, and the TTVs, and inferred that TOI-2015 hosts a second planet, TOI-2015 c, in a non-transiting configuration. Our analysis places it near a 5:3 resonance with an orbital period of Pc = 5.583 days and a mass of Mp = 8.91+0.38−0.40 M⊗. The dynamical configuration of TOI-2015 b and TOI-2015 c can be used to constrain the system’s planetary formation and migration history. Based on the mass-radius composition models, TOI-2015 b is a water-rich or rocky planet with a hydrogen-helium envelope. Moreover, TOI-2015 b has a high transmission spectroscopic metric (TSM= 149), m

关键词： Stars

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Correction: How Can Artificial Intelligence Make Medicine More Preemptive?

引用

Journal of medical Internet research 2020年第8期22卷 e23645页

作者： Usman Iqbal Leo Anthony Celi Yu-Chuan Jack Li Master Program in Global Health & Development PhD Program in Global Health & Health Security College of Public Health Taipei Medical University Taipei Taiwan. International Center for Health Information Technology Taipei Medical University Taipei Taiwan. Laboratory for Computational Physiology Massachusetts Institute of Technology Cambridge MA United States. Division of Pulmonary Critical Care and Sleep Medicine Beth Israel Deaconess Medical Center Boston MA United States. Department of Biostatistics Harvard TH Chan School of Public Health Harvard University Boston MA United States. Graduate Institute of Biomedical Informatics College of Medical Science and Technology Taipei Medical University Taipei Taiwan. Department of Dermatology Taipei Municipal Wan-Fang Hospital Taipei Taiwan. International Medical Informatics Association Geneva Switzerland.

[This corrects the article DOI: .].

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