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Correction: How Can Artificial Intelligence Make Medicine More Preemptive?

Journal of medical Internet research 2020年第8期22卷 e23645页

作者： Usman Iqbal Leo Anthony Celi Yu-Chuan Jack Li Master Program in Global Health & Development PhD Program in Global Health & Health Security College of Public Health Taipei Medical University Taipei Taiwan. International Center for Health Information Technology Taipei Medical University Taipei Taiwan. Laboratory for Computational Physiology Massachusetts Institute of Technology Cambridge MA United States. Division of Pulmonary Critical Care and Sleep Medicine Beth Israel Deaconess Medical Center Boston MA United States. Department of Biostatistics Harvard TH Chan School of Public Health Harvard University Boston MA United States. Graduate Institute of Biomedical Informatics College of Medical Science and Technology Taipei Medical University Taipei Taiwan. Department of Dermatology Taipei Municipal Wan-Fang Hospital Taipei Taiwan. International Medical Informatics Association Geneva Switzerland.

[This corrects the article DOI: .].

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Author Correction: The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci

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Nature computational science 2023年第7期3卷 658页

作者： Gengjie Jia Yu Li Xue Zhong Kanix Wang Milton Pividori Rabab Alomairy Aniello Esposito Hatem Ltaief Chikashi Terao Masato Akiyama Koichi Matsuda David E Keyes Hae Kyung Im Takashi Gojobori Yoichiro Kamatani Michiaki Kubo Nancy J Cox James Evans Xin Gao Andrey Rzhetsky Shenzhen Branch Guangdong Laboratory of Lingnan Modern Agriculture Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China. jiagengjie@***. Computational Bioscience Research Center King Abdullah University of Science and Technology Thuwal Saudi Arabia. Computer Science Program Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia. Department of Computer Science and Engineering The Chinese University of Hong Kong Hong Kong People's Republic of China. Department of Medicine and Vanderbilt Genetics Institute Vanderbilt University Medical Center Nashville TN US. Department of Medicine Institute of Genomics and Systems Biology Committee on Genomics Genetics and Systems Biology University of Chicago Chicago IL US. Department of Operations Business Analytics and Information Systems University of Cincinnati Cincinnati OH US. Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania Philadelphia PA US. Extreme Computing Research Center Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia. College of Computer Science and Engineering University of Jeddah Jeddah Saudi Arabia. HPE HPC/AI EMEA Research Laboratory Bristol UK. RIKEN Center for Integrative Medical Sciences Yokohama Japan. Clinical Research Center Shizuoka General Hospital Shizuoka Japan. Department of Applied Genetics The School of Pharmaceutical Sciences University of Shizuoka Shizuoka Japan. Department of Ophthalmology Graduate School of Medical Sciences Kyushu University Fukuoka Japan. Department of Computational Biology and Medical Sciences Graduate School of Frontier Sciences The University of Tokyo Tokyo Japan. Biological and Environmenta

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International Society for Extracellular Vesicles workshop. QuantitatEVs: Multiscale analyses, from bulk to single extracellular vesicle

Journal of Extracellular Biology

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Journal of Extracellular Biology 2024年第1期3卷 e137页

作者： Basso, Manuela Gori, Alessandro Nardella, Caterina Palviainen, Mari Holcar, Marija Sotiropoulos, Ioannis Bobis-Wozowicz, Sylwia Casarotto, Elena Ciani, Yari Suetsugu, Shiro Gualerzi, Alice Martin-Jaular, Lorena Boselli, Daniela Kashkanova, Anna Parisse, Pietro Lippens, Lien Pagliuca, Martina Blessing, Martin Frigerio, Roberto Fourniols, Thibaut Meliciano, Ana Fietta, Anna Fioretti, Paolo Vincenzo Soroczyńska, Karolina Picciolini, Silvia Salviano-Silva, Amanda Bergese, Paolo Zocco, Davide Chiari, Marcella Jenster, Guido Waldron, Levi Milosavljevic, Aleksandar Nolan, John Monopoli, Marco P. Witwer, Kenneth W. Bussolati, Benedetta Di Vizio, Dolores Falcon Perez, Juan Lenassi, Metka Cretich, Marina Demichelis, Francesca Department of Cellular Computational and Integrative Biology (CIBIO) University of Trento Trento Italy National Research Council of Italy Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR) Milan Italy EV group Molecular and Integrative Biosciences Research Program Faculty of Biological and Environmental Sciences University of Helsinki Helsinki Finland Institute of Biochemistry and Molecular Genetics Faculty of Medicine University of Ljubljana Ljubljana Slovenia Institute of Biosciences & Applications National Center for Scientific Research (NCSR) Demokritos Paraskevi Greece Faculty of Biochemistry Biophysics and Biotechnology Department of Cell Biology Jagiellonian University Krakow Poland Dipartimento di Scienze Farmacologiche e Biomolecolari “Rodolfo Paoletti” (DiSFeB) Dipartimento di Eccellenza Università degli Studi di Milano Milan Italy Division of Biological Science Graduate School of Science and Technology Nara Institute of Science and Technology Ikoma Japan IRCCS Fondazione Don Carlo Gnocchi Milan Italy Institut Curie PSL University Inserm U932 Immunity and Cancer Paris France FRACTAL (Flow Cytometry Resource Advanced Cytometry Technical Applications Laboratory) San Raffaele Scientific Institute Milan Italy Max Planck Institute for the Science of Light Erlangen Germany National Research Council of Italy Istituto Officina dei Materiali (IOM-CNR) Trieste Italy Department of Human Structure and Repair Laboratory of Experimental Cancer Research Ghent University Ghent Belgium Cancer Research Institute Ghent Ghent Belgium Molecular Predictors and New Targets in Oncology Gustave Roussy Villejuif France Clinical and Translational Oncology Scuola Superiore Meridionale Naples Italy EverZom Paris France iBET-Instituto de Biologia Experimental e Tecnológica Oeiras Portugal Department of Biomedical Sciences (DSB) University of Padua Padua Italy Fondazione Istituto di Ricerca Pediatrica Città della Speranza (IRP) Padua Italy Medical University of

The “QuantitatEVs: multiscale analyses, from bulk to single vesicle” workshop aimed to discuss quantitative strategies and harmonized wet and computational approaches toward the comprehensive analysis of extracellular vesicles (EVs) from bulk to single vesicle analyses with a special focus on emerging technologies. The workshop covered the key issues in the quantitative analysis of different EV-associated molecular components and EV biophysical features, which are considered the core of EV-associated biomarker discovery and validation for their clinical translation. The in-person-only workshop was held in Trento, Italy, from January 31^st to February 2^nd, 2023, and continued in Milan on February 3^rd with “Next Generation EVs,” a satellite event dedicated to early career researchers (ECR). This report summarizes the main topics and outcomes of the workshop. © 2024 The Authors. Journal of Extracellular Biology published by Wiley Periodicals LLC on behalf of International Society for Extracellular Vesicles.

关键词： multiomics analysis multiscale analysis quantitative biology single vesicle

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Correction to: Authors’ Reply to Letter to the Editor: Continued improvement to genetic diversity indicator for CBD

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Conservation Genetics 2021年第4期22卷 537-539页

作者： Laikre, Linda Hohenlohe, Paul A. Allendorf, Fred W. Bertola, Laura D. Breed, Martin F. Bruford, Michael W. Funk, W. Chris Gajardo, Gonzalo González-Rodríguez, Antonio Grueber, Catherine E. Hedrick, Philip W. Heuertz, Myriam Hunter, Margaret E. Johannesson, Kerstin Liggins, Libby MacDonald, Anna J. Mergeay, Joachim Moharrek, Farideh O’Brien, David Ogden, Rob Orozco-terWengel, Pablo Palma-Silva, Clarisse Pierson, Jennifer Paz-Vinas, Ivan Russo, Isa-Rita M. Ryman, Nils Segelbacher, Gernot Sjögren-Gulve, Per Waits, Lisette P. Vernesi, Cristiano Hoban, Sean Division of Population Genetics Department of Zoology Stockholm University Stockholm Sweden Institute for Bioinformatics and Evolutionary Studies Department of Biological Sciences University of Idaho Moscow USA Division of Biological Sciences University of Montana Missoula USA City College of New York New York USA College of Science and Engineering Flinders University Bedford Park Australia School of Biosciences Cardiff University Cardiff Wales UK Graduate Degree Program in Ecology Department of Biology Colorado State University Fort Collins USA Universidad de Los Lagos Lab Genetics Aquaculture & Biodiversity Osorno Chile Instituto de Investigaciones en Ecosistemas y Sustentabilidad Universidad Nacional Autónoma de México Morelia Mexico School of Life and Environmental Sciences Faculty of Science The University of Sydney Sydney Australia School of Life Sciences Arizona State University Tempe USA INRAE Univ. Bordeaux Biogeco Cestas France U.S. Geological Survey Wetland and Aquatic Research Center Gainesville USA Department of Marine Sciences University of Gothenburg Tjärnö Strömstad Sweden School of Natural and Computational Sciences Massey University Auckland New Zealand The John Curtin School of Medical Research/Research School of Biology The Australian National University Acton Australia Research Institute for Nature and Forest Geraardsbergen Belgium Aquatic Ecology Evolution and Conservation KULeuven Leuven Belgium Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark Faculty of Biological Sciences Tarbiat Modares University Tehran Iran Scottish Natural Heritage Inverness UK Royal (Dick) School of Veterinary Studies and the Roslin Institute University of Edinburgh Midlothian UK Department of Plant Science Institute of Biology University of Campinas Campinas Brazil Australian Wildlife Conservancy Subiaco East Australia Laboratoire Evolution & Div

A correction to this paper has been published: https://***/10.1007/s10592-021-01376-9

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The SCUBA-2 Large eXtragalactic Survey: 850 μm map, catalogue and the bright-end number counts of the XMM-LSS field

arXiv

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arXiv 2023年

作者： Garratt, T.K. Geach, J.E. Tamura, Y. Coppin, K.E.K. Franco, M. Ao, Y. Chen, C.-C. Cheng, C. Clements, D.L. Dai, Y.S. Dannerbauer, H. Greve, T.R. Hatsukade, B. Hwang, H.S. Jiang, L. Kohno, K. Koprowski, M.P. Michalowski, M.J. Sawicki, M. Scott, D. Shim, H. Takeuchi, T.T. Wang, W.-H. Xue, Y.Q. Yang, C. Centre for Astrophysics Research University of Hertfordshire HatfieldAL10 9AB United Kingdom Division of Particle and Astrophysical Science Nagoya University Aichi Nagoya464-8602 Japan Purple Mountain Observatory Key Laboratory for Radio Astronomy Chinese Academy of Sciences 10 Yuanhua Road Nanjing210023 China School of Astronomy and Space Science University of Science and Technology of China Anhui Hefei230026 China Academia Sinica Institute of Astronomy and Astrophysics No. 1 Section 4 Roosevelt Road Taipei10617 Taiwan Chinese Academy of Sciences South America Center for Astronomy National Astronomical Observatories CAS Beijing100101 China Imperial College London Blackett Lab Prince Consort Road LondonSW7 2AZ United Kingdom National Astronomical Observatories Chinese Academy of Sciences 20A Datun RoadChaoyang District Beijing100101 China Tenerife La LagunaE-38205 Spain Universidad de La Laguna Dpto. Astrofísica Tenerife La LagunaE-38206 Spain National Space Institute DTU Space Technical University of Denmark Elektrovej 327 Kgs. LyngbyDK-2800 Denmark Department of Physics and Astronomy University College London Gower Street LondonWC1E 6BT United Kingdom Institute of Astronomy Graduate School of Science The University of Tokyo 2-21-1 Osawa Tokyo Mitaka181-0015 Japan Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Astronomy Program Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of Kavli Institute for Astronomy and Astrophysics Peking University No. 5 Yiheyuan Road Haidian District Beijing100871 China Institute of Astronomy Faculty of Physics Astronomy and Informatics Nicolaus Copernicus University Grudziadzka 5 Torun87-100 Poland Astronomical Observatory Institute Faculty of Physics Adam Mickiewicz University ul. Sloneczna 36 Poznań60-286 Poland Department of Astronomy and P

We present 850 μm imaging of the XMM-LSS field observed for 170 hours as part of the James Clerk Maxwell Telescope SCUBA-2 Large eXtragalactic Survey (S2LXS). S2LXS XMM-LSS maps an area of 9 deg2, reaching a moderate depth of 1σ 4 mJy beam−1. This is the largest contiguous area of extragalactic sky mapped by JCMT at 850 μm to date. The wide area of the S2LXS XMM-LSS survey allows us to probe the ultra-bright (S850μm & 15 mJy), yet rare submillimetre population. We present the S2LXS XMM-LSS catalogue, which comprises 40 sources detected at >5σ significance, with deboosted flux densities in the range of 7 mJy to 48 mJy. We robustly measure the bright-end of the 850 μm number counts at flux densities >7 mJy, reducing the Poisson errors compared to existing measurements. The S2LXS XMM-LSS observed number counts show the characteristic upturn at bright fluxes, expected to be motivated by local sources of submillimetre emission and high-redshift strongly lensed galaxies. We find that the observed 850 μm number counts are best reproduced by model predictions that include either strong lensing or source blending from a 15 arcsec beam, indicating that both may make an important contribution to the observed over-abundance of bright single dish 850 μm selected sources. We make the S2LXS XMM-LSS 850 μm map and >5σ catalogue presented here publicly available. Copyright © 2023, The Authors. All rights reserved.

关键词： Blending

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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants

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science (New York, N.Y.) 2025年第6734期387卷 eadp4753页

作者： Liu, Hongbo Abedini, Amin Ha, Eunji Ma, Ziyuan Sheng, Xin Dumoulin, Bernhard Qiu, Chengxiang Aranyi, Tamas Li, Shen Dittrich, Nicole Chen, Hua-Chang Tao, Ran Tarng, Der-Cherng Hsieh, Feng-Jen Chen, Shih-Ann Yang, Shun-Fa Lee, Mei-Yueh Kwok, Pui-Yan Wu, Jer-Yuarn Chen, Chien-Hsiun Khan, Atlas Limdi, Nita A. Wei, Wei-Qi Walunas, Theresa L. Karlson, Elizabeth W. Kenny, Eimear E. Luo, Yuan Kottyan, Leah Connolly, John J. Jarvik, Gail P. Weng, Chunhua Shang, Ning Cole, Joanne B. Mercader, Josep M. Mandla, Ravi Majarian, Timothy D. Florez, Jose C. Haas, Mary E. Lotta, Luca A. Drivas, Theodore G. Vy, Ha My T Nadkarni, Girish N. Wiley, Laura K. Wilson, Melissa P. Gignoux, Christopher R. Rasheed, Humaira Thomas, Laurent F. Åsvold, Bjørn Olav Brumpton, Ben M. Hallan, Stein I. Hveem, Kristian Zheng, Jie Hellwege, Jacklyn N. Zawistowski, Matthew Zöllner, Sebastian Franceschini, Nora Hu, Hailong Zhou, Jianfu Kiryluk, Krzysztof Ritchie, Marylyn D. Palmer, Matthew Edwards, Todd L. Voight, Benjamin F. Hung, Adriana M. Susztak, Katalin Department of Medicine Renal Electrolyte and Hypertension Division University of Pennsylvania Philadelphia PA United States Institute of Diabetes Obesity and Metabolism University of Pennsylvania Philadelphia PA United States Department of Genetics University of Pennsylvania Philadelphia PA United States Penn-CHOP Kidney Innovation Center University of Pennsylvania Philadelphia PA United States Liangzhu Laboratory Zhejiang University 1369 West Wenyi Road Hangzhou Zhejiang China Department of Nephrology Children' Hospital Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China Institute of Molecular Life Sciences HUN-REN Research Center for Natural Sciences Budapest Hungary Department of Molecular Biology Semmelweis University Budapest Hungary Department of Medicine Federal University of São Paulo São Paulo Brazil Department of Biostatistics Vanderbilt University Medical Center Nashville TN United States Vanderbilt Genetics Institute Vanderbilt University Medical Center Nashville TN United States Institute of Clinical Medicine School of Medicine National Yang Ming Chiao Tung University ROC Taipei Taiwan Division of Nephrology Department of Medicine Taipei Veterans General Hospital ROC Taipei Taiwan Institute of Biomedical Sciences Academia Sinica ROC Taipei Taiwan Cardiovascular Center Taichung Veterans General Hospital Taichung Taiwan ROC National Chung Hsing University Taichung Taiwan ROC Heart Rhythm Center Division of Cardiology Department of Medicine Taipei Veterans General Hospital ROC Taipei Taiwan Department of Internal Medicine College of Medicine National Yang Ming Chiao Tung University ROC Taipei Taiwan Institute of Medicine Chung Shan Medical University Taichung Taiwan ROC Department of Medical Research Chung Shan Medical University Hospital Taichung Taiwan ROC Division of Endocrinology and Metabolism Department of Internal Medicine Kaohsiung Medical Universit

Kidney dysfunction is a major cause of mortality, but its genetic architecture remains elusive. In this study, we conducted a multiancestry genome-wide association study in 2.2 million individuals and identified 1026 (97 previously unknown) independent loci. Ancestry-specific analysis indicated an attenuation of newly identified signals on common variants in European ancestry populations and the power of population diversity for further discoveries. We defined genotype effects on allele-specific gene expression and regulatory circuitries in more than 700 human kidneys and 237,000 cells. We found 1363 coding variants disrupting 782 genes, with 601 genes also targeted by regulatory variants and convergence in 161 genes. Integrating 32 types of genetic information, we present the "Kidney Disease Genetic Scorecard" for prioritizing potentially causal genes, cell types, and druggable targets for kidney disease.

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Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing

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NATURE COMMUNICATIONS 2023年第1期14卷 7803页

作者： Chen, Ningbo Xia, Xiaoting Hanif, Quratulain Zhang, Fengwei Dang, Ruihua Huang, Bizhi Lyu, Yang Luo, Xiaoyu Zhang, Hucai Yan, Huixuan Wang, Shikang Wang, Fuwen Chen, Jialei Guan, Xiwen Liu, Yangkai Li, Shuang Jin, Liangliang Wang, Pengfei Sun, Luyang Zhang, Jicai Liu, Jianyong Qu, Kaixing Cao, Yanhong Sun, Junli Liao, Yuying Xiao, Zhengzhong Cai, Ming Mu, Lan Siddiki, Amam Zonaed Asif, Muhammad Mansoor, Shahid Babar, Masroor Ellahi Hussain, Tanveer Silva, Gamamada Liyanage Lalanie Pradeepa Gorkhali, Neena Amatya Terefe, Endashaw Belay, Gurja Tijjani, Abdulfatai Zegeye, Tsadkan Gebre, Mebrate Genet Ma, Yun Wang, Yu Huang, Yongzhen Lan, Xianyong Chen, Hong Migliore, Nicola Rambaldi Colombo, Giulia Semino, Ornella Achilli, Alessandro Sinding, Mikkel-Holger S. Lenstra, Johannes A. Cheng, Haijian Lu, Wenfa Hanotte, Olivier Han, Jianlin Jiang, Yu Lei, Chuzhao Northwest A&F University Key Laboratory of Animal Genetics Breeding and Reproduction of Shaanxi Province College of Animal Science and Technology Yangling China (GRID:grid.144022.1) (ISNI:0000 0004 1760 4150) National Institute for Biotechnology and Genetic Engineering Faisalabad Pakistan (GRID:grid.419397.1) (ISNI:0000 0004 0447 0237) Chinese Academy of Agricultural Sciences (CAAS) CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources Institute of Animal Science Beijing China (GRID:grid.410727.7) (ISNI:0000 0001 0526 1937) Yunnan Academy of Grassland and Animal Science Kunming China (GRID:grid.506866.b) Yunnan University Institute for Ecological Research and Pollution Control of Plateau Lakes School of Ecology and Environment Science Kunming China (GRID:grid.440773.3) (ISNI:0000 0000 9342 2456) Chuxiong Normal University Academy of Science and Technology Chuxiong China (GRID:grid.469523.f) (ISNI:0000 0000 9870 4997) Guangxi Vocational University of Agriculture Nanning China (GRID:grid.469523.f) Guangxi Key Laboratory of Veterinary Biotechnology Guangxi Veterinary Research Institute Nanning China (GRID:grid.418337.a) Guangxi Vocational University of Agriculture Nanning China (GRID:grid.418337.a) Southwest Forestry University College of Landscape and Horticulture Kunming China (GRID:grid.412720.2) (ISNI:0000 0004 1761 2943) Chattogram Veterinary and Animal Sciences University (CVASU) Genomics Research Group Department of Pathology and Parasitology Faculty of Veterinary Medicine Chattogram Bangladesh (GRID:grid.442958.6) National Institute for Biotechnology and Genetic Engineering Faisalabad Pakistan (GRID:grid.419397.1) (ISNI:0000 0004 0447 0237) The University of Agriculture Dera Ismail Khan Pakistan (GRID:grid.412298.4) (ISNI:0000 0000 8577 8102) Virtual University of Pakistan Department of Molecular Biology Islamabad Pakistan (GRID:grid.444943.a) (ISNI:0000 0004 0609 0887) University of Peradeniya Department of Animal Science Peradeniya Sri Lanka (GRID

Indicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral communities across a wide range of agro-ecosystems, from extremely hot semiarid regions to hot humid tropical regions. However, their adaptive genetic changes following their dispersal into East Asia from the Indian subcontinent have remained poorly documented. Here, we characterize their global genetic diversity using high-quality whole-genome sequencing data from 354 indicine cattle of 57 breeds/populations, including major indicine phylogeographic groups worldwide. We reveal their probable migration into East Asia was along a coastal route rather than inland routes and we detected introgression from other bovine species. Genomic regions carrying morphology-, immune-, and heat-tolerance-related genes underwent divergent selection according to Asian agro-ecologies. We identify distinct sets of loci that contain promising candidate variants for adaptation to hot semi-arid and hot humid tropical ecosystems. Our results indicate that the rapid and successful adaptation of East Asian indicine cattle to hot humid environments was promoted by localized introgression from banteng and/or gaur. Our findings provide insights into the history and environmental adaptation of indicine cattle.

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Worldwide Soundscapes: A Synthesis of Passive Acoustic Monitoring Across Realms

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Global Ecology and Biogeography 2025年第5期34卷

作者： Kevin F. A. Darras Rodney A. Rountree Steven L. Van Wilgenburg Anna F. Cord Frederik Pitz Youfang Chen Lijun Dong Agnès Rocquencourt Camille Desjonquères Patrick Mauritz Diaz Tzu-Hao Lin Théophile Turco Louise Emmerson Tom Bradfer-Lawrence Amandine Gasc Sarah Marley Marcus Salton Laura Schillé Paul J. Wensveen Shih-Hung Wu Adriana C. Acero-Murcia Orlando Acevedo-Charry Matyáš Adam Jacopo Aguzzi Irmak Akoglu M. Clara P. Amorim Mina Anders Michel André Alexandre Antonelli Leandro Aparecido Do Nascimento Giulliana Appel Stephanie Archer Christos Astaras Andrey Atemasov Jamieson Atkinson Joël Attia Emanuel Baltag Luc Barbaro Fritjof Basan Carly Batist Julio Ernesto Baumgarten Just T. Bayle Sempere Kristen Bellisario Asaf Ben David Oded Berger-Tal Frédéric Bertucci Matthew G. Betts Iqbal S. Bhalla Thiago Bicudo Marta Bolgan Sara Bombaci Gerard Bota Martin Boullhesen Robert A. Briers Susannah Buchan Michal Budka Katie Burchard Giuseppa Buscaino Alice Calvente Marconi Campos-Cerqueira Maria Isabel Carvalho Gonçalves Maria Ceraulo Maite Cerezo-Araujo Gunnar Cerwén Adams A. Chaskda Maria Chistopolova Christopher W. Clark Kieran D. Cox Benjamin Cretois Chapin Czarnecki Luis P. da Silva Wigna da Silva Laurence H. De Clippele David de la Haye Ana Silvia de Oliveira Tissiani Devin de Zwaan M. Eugenia Degano Jessica Deichmann Joaquin del Rio Christian Devenish Ricardo Díaz-Delgado Pedro Diniz Dorgival Diógenes Oliveira-Júnior Thiago Dorigo Saskia Dröge Marina Duarte Adam Duarte Kerry Dunleavy Robert Dziak Simon Elise Hiroto Enari Haruka S. Enari Florence Erbs Britas Klemens Eriksson Pınar Ertör-Akyazi Nina C. Ferrari Luane Ferreira Abram B. Fleishman Paulo J. Fonseca Bárbara Freitas Nicholas R. Friedman Jérémy S. P. Froidevaux Svetlana Gogoleva Carolina Gonzaga José Miguel González Correa Eben Goodale Benjamin Gottesman Ingo Grass Jack Greenhalgh Jocelyn Gregoire Samuel Haché Jonas Hagge William Halliday Antonia Hammer Tara Hanf-Dressler Sylvain Haupert Samara Haver Becky Heath Daniel Hending Jose Hernandez-Blanco Dennis Higgs EFNO ECODIV INRAE Domaine des Barres Nogent-sur-Vernisson France Sustainable Agricultural Systems & Engineering Lab School of Engineering Westlake University Hangzhou Zhejiang China Chair of Computational Landscape Ecology Faculty of Environmental Sciences Dresden University of Technology Dresden Germany Biology Department University of Victoria Victoria British Columbia Canada The Fish Listener Waguoit Massachusetts USA Terrestrial Unit Prairie Region Canadian Wildlife Service Environment & Climate Change Canada Prairie & Northern Wildlife Research Centre Saskatoon Saskatchewan Canada Agro-ecological Modeling Group Faculty of Agriculture University of Bonn Bonn Germany Marine Mammal and Marine Bioacoustics Laboratory Department of Deep Sea Science Institute of Deep-sea Science and Engineering Chinese Academy of Sciences Sanya Hainan China Institut de Systématique Évolution Biodiversité Muséum National d’Histoire Naturelle Paris France Université Grenoble Alpes Université Savoie Mont Blanc CNRS LECA Grenoble France Climate Change and Biodiversity Hanns R. Neumann Stiftung Indonesia Muaradua Indonesia Biodiversity Research Center Academia Sinica Nankang Taipei Taiwan ENES Bioacoustics Research Laboratory University of Saint-Etienne CRNL CNRS UMR 5292 Inserm UMR_S 1028 Saint-Etienne France Australian Antarctic Division Science Branch Department of Climate Change Energy Environment and Water Channel Highway Kingston Tasmania Australia Biological and Environmental Sciences University of Stirling Stirling Scotland Centre for Conservation Science RSPB Edinburgh UK IMBE Aix Marseille Univ Avignon Univ CNRS IRD Aix-en-Provence France Scotland's Rural College Craibstone Estate Aberdeen UK BIOGECO INRAE University of Bordeaux Cestas France Westman Islands Research Centre University of Iceland Vestmannaeyjar Iceland Qigu Research Center Taiwan Biodiversity Research Institute Nantou County Taiwan Programa de Pós-graduação em Ecologia

Aim The urgency for remote, reliable and scalable biodiversity monitoring amidst mounting human pressures on ecosystems has sparked worldwide interest in Passive Acoustic Monitoring (PAM), which can track life underwater and on land. However, we lack a unified methodology to report this sampling effort and a comprehensive overview of PAM coverage to gauge its potential as a global research and monitoring tool. To address this gap, we created the Worldwide Soundscapes project, a collaborative network and growing database comprising metadata from 416 datasets across all realms (terrestrial, marine, freshwater and subterranean). Location Worldwide, 12,343 sites, all ecosystem types. Time Period 1991 to present. Major Taxa Studied All soniferous taxa. Methods We synthesise sampling coverage across spatial, temporal and ecological scales using metadata describing sampling locations, deployment schedules, focal taxa and audio recording parameters. We explore global trends in biological, anthropogenic and geophysical sounds based on 168 selected recordings from 12 ecosystems across all realms. Results Terrestrial sampling is spatially denser (46 sites per million square kilometre—Mkm 2 ) than aquatic sampling (0.3 and 1.8 sites/Mkm 2 in oceans and fresh water) with only two subterranean datasets. Although diel and lunar cycles are well sampled across realms, only marine datasets (55%) comprehensively sample all seasons. Across the 12 ecosystems selected for exploring global acoustic trends, biological sounds showed contrasting diel patterns across ecosystems, declined with distance from the Equator, and were negatively correlated with anthropogenic sounds. Main Conclusions PAM can inform macroecological studies as well as global conservation and phenology syntheses, but representation can be improved by expanding terrestrial taxonomic scope, sampling coverage in the high seas and subterranean ecosystems, and spatio-temporal replication in freshwater habitats. Overall, this

关键词： ARU automated sound recorder biodiversity conservation biology ecoacoustics IUCN GET realm Passive Acoustic Monitoring phenology soundscape ecology

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Correction: Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks

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Leukemia 2024年第8期38卷 1867页

作者： Jonathan D Diedrich Qian Dong Daniel C Ferguson Brennan P Bergeron Robert J Autry Maoxiang Qian Wenjian Yang Colton Smith James B Papizan Jon P Connelly Kohei Hagiwara Kristine R Crews Shondra M Pruett-Miller Ching-Hon Pui Jun J Yang Mary V Relling William E Evans Daniel Savic Hematological Malignancies Program and Center for Precision Medicine in Leukemia St. Jude Children's Research Hospital Memphis TN USA. Department of Pharmaceutical Sciences St. Jude Children's Research Hospital Memphis TN USA. Graduate School of Biomedical Sciences St. Jude Children's Research Hospital Memphis TN USA. Integrated Biomedical Sciences Program University of Tennessee Health Science Center Memphis TN USA. Department of Cell and Molecular biology and Center for Advanced Genome Engineering St. Jude Children's Research Hospital Memphis TN USA. Department of Computational Biology St. Jude Children's Research Hospital Memphis TN USA. Department of Oncology St. Jude Children's Research Hospital Memphis TN USA. Department of Pathology St. Jude Children's Research Hospital Memphis TN USA. Hematological Malignancies Program and Center for Precision Medicine in Leukemia St. Jude Children's Research Hospital Memphis TN USA. daniel.savic@***. Department of Pharmaceutical Sciences St. Jude Children's Research Hospital Memphis TN USA. daniel.savic@***. Integrated Biomedical Sciences Program University of Tennessee Health Science Center Memphis TN USA. daniel.savic@***.

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A light in the dark: searching for electromagnetic counterparts to black hole-black hole mergers in LIGO/Virgo O3 with the Zwicky Transient Facility

arXiv

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arXiv 2022年

作者： Graham, Matthew J. McKernan, Barry Ford, K.E. Saavik Stern, Daniel Djorgovski, S.G. Coughlin, Michael Burdge, Kevin B. Bellm, Eric C. Helou, George Mahabal, Ashish A. Masci, Frank J. Purdum, Josiah Rosnet, Philippe Rusholme, Ben California Institute of Technology 1200 E. California Blvd PasadenaCA91125 United States Department of Science CUNY Borough of Manhattan Community College 199 Chambers Street New YorkNY10007 United States Department of Astrophysics American Museum of Natural History Central Park West New YorkNY10028 United States Physics Program CUNY Graduate Center 365 5th Avenue New YorkNY10016 United States Center for Computational Astrophysics Flatiron Institute New YorkNY10010 United States Jet Propulsion Laboratory California Institute of Technology 4800 Oak Grove Drive PasadenaCA91109 United States School of Physics and Astronomy University of Minnesota MinneapolisMN55455 United States Department of Physics Massachusetts Institute of Technology CambridgeMA02139 United States Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States DIRAC Institute Department of Astronomy University of Washington 3910 15th Avenue NE SeattleWA98195 United States IPAC California Institute of Technology 1200 E. California Blvd PasadenaCA91125 United States Division of Physics Mathematics and Astronomy California Institute of Technology PasadenaCA91125 United States Center for Data Driven Discovery California Institute of Technology PasadenaCA91125 United States Caltech Optical Observatories California Institute of Technology PasadenaCA91125 United States Université Clermont Auvergne CNRS IN2P3 LPC Clermont-FerrandF-63000 France

The accretion disks of active galactic nuclei (AGN) are promising locations for the merger of compact objects detected by gravitational wave (GW) observatories. Embedded within a baryon-rich, high density environment, mergers within AGN are the only GW channel where an electromagnetic (EM) counterpart must occur (whether detectable or not). Considering AGN with unusual flaring activity observed by the Zwicky Transient Facility (ZTF), we describe a search for candidate EM counterparts to binary black hole (BBH) mergers detected by LIGO/Virgo in O3. After removing probable false positives, we find nine candidate counterparts to BBH mergers during O3 (seven in O3a, two in O3b) with a p-value of 0.0019. Based on ZTF sky coverage, AGN geometry, and merger geometry, we expect ≈ 3(NBBH/83)(fAGN/0.5) potentially detectable EM counterparts from O3, where NBBH is the total number of observed BBH mergers and fAGN is the fraction originating in AGN. Further modeling of breakout and flaring phenomena in AGN disks is required to reduce our false positive rate. Two of the events are also associated with mergers with total masses > 100M☉, which is the expected rate for O3 if hierarchical (large mass) mergers occur in the AGN channel. Candidate EM counterparts in future GW observing runs can be better constrained by coverage of the Southern sky as well as spectral monitoring of unusual AGN flaring events in LIGO/Virgo alert volumes. A future set of reliable AGN EM counterparts to BBH mergers will yield an independent means of measuring cosmic expansion (H0) as a function of redshift. © 2022, CC BY.

关键词： Gravity waves

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