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2017 IEEE Congress on Evolutionary Computation, CEC 2017

作者： Cota, Luciano Perdigao Guimaraes, Frederico Gadelha De Oliveira, Fernando B. Souza, Marcone J. Freitas Graduate Program in Electrical Engineering Federal University of Minas Gerais Belo Horizonte Brazil Department of Electrical Engineering Universidade Federal de Minas Gerais Belo Horizonte Brazil Department of Computer and Systems Universidade Federal de Ouro Preto João Monlevade Brazil Department of Computer Science Universidade Federal de Ouro Preto Brazil

ISBN: (纸本)9781509046010

This work deals with the Unrelated Parallel Machine Scheduling Problem with Setup Times, with the objective of minimizing the makespan. It is proposed an Adaptive Large Neighborhood Search (ALNS) metaheuristic using Learning Automata (LA) to adapt the probabilities of using removal and insertion heuristics and methods. A computable function in the LA updates the probability vector for selecting the actions, corresponding to six removal and six insertion methods. We also propose a new insertion method based on Hungarian algorithm, which is applied to solve subproblems optimally. Computational experiments are performed to verify the performance of the proposed method. A set of instances available in the literature with problems up to 150 jobs and 10 machines is employed in the experiments. The proposed LA-ALNS is compared against three other algorithms from the literature. The results suggest that our algorithm has better performance in most of cases (88%) under the defined conditions of experiments. Statistical tests also suggest that LA-ALNS is better than the other algorithms from the literature. The proposed method is able to automatically choose the most suitable heuristics for the instance of the problem, through adaptation and learning in the Learning Automata. © 2017 IEEE.

关键词： Heuristic methods

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StimDust: A 1.7 mm3, implantable wireless precision neural stimulator with ultrasonic power and communication

arXiv

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arXiv 2018年

作者： Piech, David K. Johnson, Benjamin C. Shen, Konlin Meraj Ghanbari, M. Li, Ka Yiu Neely, Ryan M. Kay, Joshua E. Carmena, Jose M. Maharbiz, Michel M. Muller, Rikky San Francisco Graduate Program in Bioengineering University of California Berkeley BerkeleyCA94720 United States Department of Electrical Engineering and Computer Sciences University of California Berkeley BerkeleyCA94720 United States Department of Electrical Engineering and Computer Engineering Boise State University BoiseID83725 United States Helen Wills Neuroscience Institute University of California Berkeley BerkeleyCA94720 United States Chan-Zuckerberg Biohub San FranciscoCA94158 United States

Neural stimulation is a powerful technique for modulating physiological functions and for writing information into the nervous system as part of brain-machine interfaces. Current clinically approved neural stimulators require batteries and are many cubic centimeters in size- typically much larger than their intended targets. We present a complete wireless neural stimulation system consisting of a 1.7 mm3 wireless, batteryless, leadless implantable stimulator (the "mote"), an ultrasonic wireless link for power and bi-directional communication, and a hand-held external transceiver. The mote consists of a piezoceramic transducer, an energy storage capacitor, and a stimulator integrated circuit (IC). The IC harvests ultrasonic power with high efficiency, decodes stimulation parameter downlink data, and generates current-controlled stimulation pulses. Stimulation parameters are time-encoded on the fly through the wireless link rather than being programmed and stored on the mote, enabling complex stimulation protocols with high-temporal resolution and closed-loop capability while reducing power consumption and on-chip memory requirements. Uplink data indicates whether the mote is currently stimulating;it is encoded by the mote via backscatter modulation and is demodulated at the external transceiver. We show that the system operates at an acoustic power one fifth the FDA limit for diagnostic ultrasound and is robust to expected real-world acoustic link misalignment. We investigate the performance of the system with motes acutely implanted with a cuff on the sciatic nerve of anesthetized rats and show highly repeatable stimulation across a wide range of physiological responses. Copyright © 2018, The Authors. All rights reserved.

关键词： Electrophysiology

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Consistency of surface electromyography assessment at lower limb selected muscles during vertical countermovement 39

Consistency of surface electromyography assessment at lower ...

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39th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBC 2017

作者： Rodrigues, Carlos Correia, Miguel Abrantes, Joao M. C. S. Nadal, Jurandir Rodrigues, Marco A. Benedetti Centre for Biomedical Engineering Research INESC TEC Porto4200 - 465 Portugal Department of Electrical and Computer Engineering Faculty of Engineering University of Porto 4200-465 Portugal MovLab Interactions and Interfaces Lab Lusófona University of Humanities and Technologies Lisboa1749-024 Portugal Biomedical Engineering Program Federal University of Rio de Janeiro 21941-972 Brazil Graduate Program in Electrical Engineering Federal University of Pernambuco Recife50740-550 Brazil

ISBN: (纸本)9781509028092

Given the difficulty of invasive methods to assess muscle action during natural human movement, surface electromyography (sEMG) has been increasingly used to capture muscle activity in relation to kinesiological analysis of specific tasks. Isolated isometric, concentric and eccentric forms of muscle action have been receiving the most attention for research purposes. Nevertheless natural muscle action frequently involves the use of a preceding eccentric muscle action as a form of potentiation of immediate muscle concentric action, in what is designated as muscle stretch-shortening cycle (SSC). The most frequently applied protocols for the evaluation of SSC on vertical jumps are by virtue of their reproducibility and control of experimental conditions, squat jump (SJ) without countermovement (CM), countermovement jump (CMJ) with long CM and drop jump (DJ) with short CM. The methods used to extract information and relationship of the captured signals also present a high diversity, with the question about the consistency of the methods and obtained results. The objective of this study is to evaluate the consistency of the analysis and results by applying different EMGs signal analysis techniques related to strategic muscle groups of the lower limbs at different countermovement evaluated in vertical jumps. Raw sEMG signals of 5 lower limb muscles of 6 subjects during SJ, CMJ and DJ were rectified, filtered and obtained their envelope, and then correlated (CR) for detection of synergistic, agonist and antagonist activity, applied principal component analysis (PCA) for the detection of uncorrelated components explaining maximum variability and normalized cross-correlation (CCRN) for detection of maximum correlations and time lag. CR of EMG envelopes presented higher coactivities (CoA) in DJ relative to SJ and these CoA superior to CMJ with greater synergy in DJ relative to SJ and CMJ that present several loop cycles corresponding to time lag of activity. CCRN of the EMG e

关键词： Muscles Correlation Electromyography Principal component analysis Eigenvalues and eigenfunctions Electronic mail Radio frequency

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Resonant photonic structures in porous silicon for biosensing 9

Resonant photonic structures in porous silicon for biosensin...

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Frontiers in Biological Detection: From Nanosensors to Systems IX

作者： Zhao, Yiliang Rodriguez, Gilberto A. Graham, Yasmin M. Cao, Tengfei Gaur, Girija Weiss, Sharon M. Interdisciplinary Graduate Program in Materials Science Vanderbilt University NashvilleTN37235 United States Department of Electrical Engineering and Computer Science Vanderbilt University NashvilleTN37235 United States Department of Mechanical Engineering University of Maryland Baltimore County BaltimoreMD21250 United States

ISBN: (数字)9781510606043

ISBN: (纸本)9781510606036

The formation of resonant photonic structures in porous silicon leverages the benefit of high surface area for improved molecular capture that is characteristic of porous materials with the advantage of high detection sensitivity that is a feature of resonant optical devices. This review provides an overview of the biosensing capabilities of a variety of resonant porous silicon photonic structures including microcavities, Bloch surface waves, ring resonators, and annular Bragg resonators. Detection sensitivities > 1000 nm/RIU are achieved for small molecule detection. The challenge of detecting molecules that approach and exceed the pore diameter is also addressed. © 2017 SPIE.

关键词： Porous silicon

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Probing the universality of topological defect formation in a quantum annealer: Kibble-Zurek mechanism and beyond

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Physical Review Research 2020年第3期2卷 033369-033369页

作者： Yuki Bando Yuki Susa Hiroki Oshiyama Naokazu Shibata Masayuki Ohzeki Fernando Javier Gómez-Ruiz Daniel A. Lidar Sei Suzuki Adolfo del Campo Hidetoshi Nishimori Institute of Innovative Research Tokyo Institute of Technology Nagatsuta-cho Midori-ku Yokohama 226-8503 Japan Institute of Innovative Research Tokyo Institute of Technology Oh-okayama Meguro-ku Tokyo 152-8550 Japan Department of Physics Tohoku University Sendai 980-8578 Japan Graduate School of Information Sciences Tohoku University Sendai 980-8579 Japan Sigma-i Co. Ltd. Konan Minato-ku Tokyo 108-0075 Japan Donostia International Physics Center E-20018 San Sebastián Spain Departments of Electrical and Computer Engineering Chemistry and Physics University of Southern California Los Angeles California 90089 USA Center for Quantum Information Science & Technology University of Southern California Los Angeles California 90089 USA Department of Liberal Arts Saitama Medical University Moroyama Saitama 350-0495 Japan IKERBASQUE Basque Foundation for Science E-48013 Bilbao Spain Department of Physics University of Massachusetts Boston 100 Morrissey Boulevard Boston Massachusetts 02125 USA RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS) Wako Saitama 351-0198 Japan

The number of topological defects created in a system driven through a quantum phase transition exhibits a power-law scaling with the driving time. This universal scaling law is the key prediction of the Kibble-Zurek mechanism (KZM), and testing it using a hardware-based quantum simulator is a coveted goal of quantum information science. Here we provide such a test using quantum annealing. Specifically, we report on extensive experimental tests of topological defect formation via the one-dimensional transverse-field Ising model on two different D-Wave quantum annealing devices. We find that the quantum simulator results can indeed be explained by the KZM for open-system quantum dynamics with phase-flip errors, with certain quantitative deviations from the theory likely caused by factors such as random control errors and transient effects. In addition, we probe physics beyond the KZM by identifying signatures of universality in the distribution and cumulants of the number of kinks and their decay, and again find agreement with the quantum simulator results. This implies that the theoretical predictions of the generalized KZM theory, which assumes isolation from the environment, applies beyond its original scope to an open system. We support this result by extensive numerical computations. To check whether an alternative, classical interpretation of these results is possible, we used the spin-vector Monte Carlo model, a candidate classical description of the D-Wave device. We find that the degree of agreement with the experimental data from the D-Wave annealing devices is better for the KZM, a quantum theory, than for the classical spin-vector Monte Carlo model, thus favoring a quantum description of the device. Our work provides an experimental test of quantum critical dynamics in an open quantum system, and paves the way to new directions in quantum simulation experiments.

关键词： Critical exponents Nonequilibrium statistical mechanics Open quantum systems Quantum computation Quantum master equation Quantum simulation Quantum statistical mechanics Quantum spin models

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Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects

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Cell Host & Microbe 2025年

作者： Stephany Flores Ramos Nicole Siguenza Wuling Zhong Ipsita Mohanty Amulya Lingaraju R. Alexander Richter Smruthi Karthikeyan April L. Lukowski Qiyun Zhu Wilhan D.G. Nunes Jasmine Zemlin Zhenjiang Zech Xu Jeff Hasty Pieter C. Dorrestein Satchidananda Panda Rob Knight Amir Zarrinpar Division of Gastroenterology University of California San Diego La Jolla CA USA Biomedical Sciences Graduate Program University of California San Diego La Jolla CA USA Department of Pediatrics University of California San Diego La Jolla CA USA Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego La Jolla CA USA Division of Engineering and Applied Science California Institute of Technology Pasadena CA USA Scripps Institution of Oceanography University of California San Diego La Jolla CA USA School of Life Sciences Arizona State University Tempe AZ USA Biodesign Center for Fundamental and Applied Microbiomics Arizona State University Tempe AZ USA Collaborative Mass Spectrometry Innovation Center Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego La Jolla CA USA Key Laboratory of Food Science and Technology Nanchang University Nanchang China Shu Chien-Gene Lay Department of Bioengineering University of California San Diego La Jolla CA USA Center for Microbiome Innovation University of California San Diego La Jolla CA USA Synthetic Biology Institute University of California San Diego La Jolla CA USA Salk Institute for Biological Studies La Jolla CA USA Department of Computer Science and Engineering University of California San Diego La Jolla CA USA Halıcıoğlu Data Science Institute University of California San Diego La Jolla CA USA Moores Cancer Center University of California San Diego La Jolla CA USA Division of Gastroenterology Jennifer Moreno Department of Veterans Affairs Medical Center La Jolla CA USA Institute of Diabetes and Metabolic Health University of California San Diego La Jolla CA USA

Diurnal rhythmicity in the gut maintains gut integrity, circadian rhythms, and metabolic homeostasis. However, existing studies focus on microbial composition rather than transcriptional activity. To understand microbial functional dynamics, we characterize diurnal fluctuations in the mouse cecal metatranscriptome and metagenome under high-fat diet and time-restricted feeding (TRF). We show that metatranscriptomics uncovers TRF-induced time-dependent microbial functional shifts that are undetectable with metagenomics alone. We also found bile salt hydrolase ( bsh ) from Dubosiella newyorkensis exhibits diurnal expression in the TRF group. engineering this bsh , along with other candidates, into a native E. coli chassis reveals distinct differences in deconjugation and amidation activities, underscoring functional specificity. In vivo , a D. newyorkensis bsh improves insulin sensitivity, glucose tolerance, and body composition, suggesting a direct role in TRF metabolic benefits. This study highlights how coupling metatranscriptomics with engineered bacterial systems is a powerful approach for uncovering time-dependent bacterial functions related to health and disease.

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Modelling and reducing fuel flow pulsation of a fuel-metering system during pump mode switching in a turbofan engine

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IOP Conference Series: Earth and Environmental Science 2019年第5期240卷

作者： S Masuda F Shimizu M Fuchiwaki K Tanaka Control Systems Engineering Department Research & Engineering Division Aero Engines Space & Defense Business Area IHI Corporation 229 Tonogaya Mizuho-machi Nishitama-gun Tokyo 190-1297 Japan Department of Computer Science and Systems Engineering Doctoral Program Graduate School of Computer Science and Systems Engineering Kyushu Institute of Technology 680-4 kawazu Iizuka-shi Fukuoka 820-8502 Japan Department of Mechanical Information Science and Technology School of Computer Science and Systems Engineering Kyushu Institute of Technology 680-4 kawazu Iizuka-shi Fukuoka 820-8502 Japan

In this research, the transient characteristics of a new type fuel metering system for aircraft turbofan engines using two types of pumps, a gear pump and a centrifugal pump, were studied by modelling and simulation. This new fuel metering system is capable of hydraulically unloading the operating state of each pump by the pump mode switching mechanism within the permissible range of the pump rotation speed and the fuel flow rate and it is possible to reduce the fuel temperature rise due to the pressure loss in the circuit in the operation region of the entire fuel system. In addition to this, by using a small centrifugal pump that can realize high discharge flow rate, it is possible to reduce weight compared to the conventional fuel system. However, when the pump mode is switched, unexpected fluctuation in the fuel flow rate can occur when a large change in the inlet pressure of the system occurs, the pressure control unit cannot follow the change, and the transient phenomenon cannot be suppressed. At this time, the pressure waveform generated at the time of changing the pump mode includes a high frequency component such that the pressure control unit, which plays a role of keeping the metering valve differential pressure constant, cannot follow up. Therefore, in this paper, we focused on the frequency of the pressure change waveform when the pump mode was changed and studied the model of the fuel system inlet pressure in the gear pump mode. Based on that model, we propose a method to reduce the frequency characteristics of the pressure change occurring at the time of pump mode change.

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A blind deconvolution approach to discontinuity location and characterization in ultrasonic nondestructive testing

A blind deconvolution approach to discontinuity location and...

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European Signal Processing Conference (EUSIPCO)

作者： Giovanni A. Guarneri Daniel R. Pipa Flávio Neves Lúcia V. R. de Arruda Graduate Program in Electrical Engineering (PPGEE) Federal University of Technology - Paraná (UTFPR) Pato Branco Paraná Brazil Graduate Program in Electrical and Computer Engineering (CPGEI) Federal University of Technology - Paraná (UTFPR) Curitiba Paraná Brazil

This paper presents a new algorithm for discontinuity location and characterization using A-scan signals from an ultrasonic inspection system. The algorithm is based on solving an inverse problem in which the observation model is different from that traditionally used. In this model, the input vector represents the location of the geometrical center of the discontinuity and the scattering amplitude of the discontinuity is embedded in the impulse response of the ultrasonic inspection system. First, we jointly estimate the locations and the scattering amplitudes of the discontinuities from the acquired signals. Then, the geometrical parameters of the discontinuities are calculated from the estimated scattering amplitude. The method is tested to characterize side-drilled holes using both synthetic and real data. The results demonstrates the effectiveness of the algorithm.

关键词： Signal processing algorithms Synchronous digital hierarchy Scattering Transducers Acoustics Approximation algorithms Europe

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Evaluation of an Instrument to Identify Factors that Impact the Motivation and Engagement of Undergraduate Students in Computing

Evaluation of an Instrument to Identify Factors that Impact ...

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Frontiers in Education (FIE) Conference

作者： Pablo Schoeffel Raul Sidnei Wazlawick Vinicius Faria Culmant Ramos Adilson Vahldick Marcelo de Souza Graduate Program in Computer Science Federal University of Santa Catarina Florianópolis Brazil Department of Informatics and Statistics Federal University of Santa Catarina Florianópolis Brazil Department of Information and Communication Technologies Federal University of Santa Catarina Araranguá Brazil Departament of Software Engineering University of Santa Catarina State Ibirama Brazil

ISBN: (纸本)9781538611753;9781538611746

This Research Paper presents the evaluation of an instrument to identify the impact of motivation and engagement factors in undergraduate students in computing. Although researches indicate a direct impact of motivation and engagement on student performance and retention, few studies have been found that address which factors are relevant in this process. The instrument is a questionnaire based on the compilation of several works of the literature containing 48 items divided into 6 groups: personal and demographic data, general perception about motivation, perception about the university, student behavior, perception about program and perception about classes/teachers. The questionnaire evaluation is based on a case study with 112 undergraduate students in Software engineering. As a result, we found that the questionnaire can be considered reliable (Cronbach's alpha = .8904). Considering the validity of constructs, we found an acceptable degree of correlation between the most pair of items in each group (averaging 63%). We also found that the item-total correlation coefficient was only not adequate for one factor group, indicating satisfactory correlation for all other items. Finally, we found that the number of factors is coherent, but there are several items from different groups strongly correlated, indicating the need for a reorganization.

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Non-reciprocal willis coupling in zero-index moving media

arXiv

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arXiv 2018年

作者： Quan, Li Sounas, Dimitrios L. Alù, Andrea Department of Electrical and Computer Engineering University of Texas at Austin AustinTX78712 United States Department of Electrical and Computer Engineering Wayne State University DetroitMI48202 United States Photonics Initiative Advanced Science Research Center City University of New York New YorkNY10031 United States Physics Program Graduate Center City University of New York New YorkNY10016 United States Department of Electrical Engineering City College of The City University of New York NY10031 United States

Mechanical motion can break the symmetry in which sound travels in a medium, but significant non-reciprocity is typically achieved only for very large motion speeds. Here we combine moving media with zero-index acoustic propagation, yielding extreme non-reciprocity and induced bianisotropy for modest applied speeds. The metamaterial is formed by an array of waveguides loaded by Helmholtz resonators, and it exhibits opposite signs of the refractive index sustained by asymmetric Willis coupling for propagation in opposite directions. We use this response to design a nonreciprocal acoustic lens focusing only when excitation from one side, with applications for imaging and ultrasound technology. Copyright © 2018, The Authors. All rights reserved.

关键词： Refractive index

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