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Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury

Research on Biomedical engineering 2020年第3期36卷 203-212页

作者： Krueger, Eddy Popović-Maneski, Lana Neto, Guilherme Nunes Nogueira Mendonça Scheeren, Eduardo Fiusa, Jessika Mehret Nohama, Percy Neural Engineering and Rehabilitation Laboratory Universidade Estadual de Londrina LondrinaPR Brazil Graduate Program in Rehabilitation Sciences UEL-UNOPAR Campus Universitário s/n zipcode LondrinaPR86051-990 Brazil Institute of Technical Sciences of the Serbian Academy of Sciences and Arts KnezMihailova 35/IV zipcode Belgrade11000 Serbia Graduate Program in Health Technology Pontifícia Universidade Católica do Paraná Rua Imaculada Conceição 1155 Prado Velho zipcode CuritibaPR80215-901 Brazil Graduate Program in Electrical and Computer Engineering Universidade Tecnológica Federal do Paraná Av. Sete de Setembro 3165 zipcode CuritibaPR80230-901 Brazil

Purpose: Functional electrical stimulation (FES) is a method of activating paralyzed muscles. During FES application, fast muscle fatigue can occur (the inability of stimulated muscles to generate force). Therefore, it is beneficial to estimate the muscle fatigue for FES closed-loop control for walking to prevent unexpected muscle collapse and adapt the FES strategy in real time. Mechanomyography (MMG) is a noninvasive technique for registering myofiber vibrations, representing an ideal candidate for the provision of feedback. The hypothesis was that MMG signals could effectively detect muscle fatigue and, thus, provide feedback. Methods: We tested this hypothesis by analyzing the wavelet transform of signals from an MMG sensor positioned over the rectus femoris muscle during electrically evoked contractions in subjects with spinal cord injury (SCI). The signals were collected from a total of 24 lower limb muscles. We investigated both legs of 15 participants with spinal cord injury (male, YOA = 27.13 ± 5.05, M = 75.8 ± 10.35 kg, and H = 1.78 ± 0.07 m, American Spinal Injury Impairment Scale (AIS) A and B). All MMG signals were analyzed in 12 frequency bands from 5 to 53 Hz. Results: We found different trends in the magnitudes in different frequency bands. The magnitude decreased in 13, 16, 20, 25, and 35 Hz bands in correlation with fatigue. The greatest statistical difference was found at 20 Hz and 25 Hz. Conclusion: This result suggests that processed MMG signals indicate muscle fatigue and can, thus, be used as the feedback in FES systems. © 2020, Sociedade Brasileira de Engenharia Biomedica.

关键词： Muscle

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Biophysics of amplitude-modulated giga-hertz electromagnetic waves stimulation

Biophysics of amplitude-modulated giga-hertz electromagnetic...

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Asilomar Conference on Signals, Systems & computers

作者： Fatima Ahsan Aravind C. Govindaraju Robert M. Raphael Taiyun Chi Sameer A. Sheth Wayne Goodman Behnaam Aazhang Department of Electrical and Computer Engineering Rice University Houston TX USA Applied Physics Graduate Program Smalley-Curly Institute Rice University Houston TX Department of Bioengineering Rice University Houston TX USA Department of Neurosurgery Baylor College of Medicine Houston TX USA Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine Houston TX USA

This paper presents the biophysical modeling for neuronal stimulation caused by amplitude-modulated giga-hertz (GHz) electromagnetic (EM) waves. We model a 1D cable equation for electrical signal propagation in a vestibular ganglion neuronal fiber and use Hodgkin-Huxley formalism to model voltage-dependent channel conductances. We find out that for a given stimulation signal strength, the GHz waveform amplitude-modulated at a low frequency of Δf causes neuronal firing with the frequency of Δf whereas the continuous wave GHz did not elicit any neuronal firing. Moreover, the voltage-dependent channel gating dynamics of the Δf amplitude-modulated GHz stimulation matches that of a simple low frequency stimulation at Δf. Additionally, we find that the modulation depth controls the firing rate of the neurons. The significance of this property is that the amplitude modulation caused by the interference of two similar high frequency signals could be leveraged to focally excite neurons at depth without stimulating overlying cortical regions. These theoretical predictions based on the Hodgkin-Huxley model can later be tested experimentally.

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Quantifying Efficiency of Remote Excitation for Surface Enhanced Raman Spectroscopy in Molecular Junctions

arXiv

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arXiv 2023年

作者： Liao, Shusen Zhu, Yunxuan Ye, Qian Sanders, Stephen Yang, Jiawei Alabastri, Alessandro Natelson, Douglas Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States Department of Physics and Astronomy Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States

Surface-enhanced Raman spectroscopy (SERS) is enabled by local surface plasmon resonances (LSPRs) in metallic nanogaps. When SERS is excited by direct illumination of the nanogap, the background heating of lattice and electrons can prevent further manipulation of the molecules. To overcome this issue, we report SERS in electromigrated gold molecular junctions excited remotely: surface plasmon polaritons (SPPs) are excited at nearby gratings, propagate to the junction, and couple to the local nanogap plasmon modes. Like direct excitation, remote excitation of the nanogap can generate both SERS emission and an open-circuit photovoltage (OCPV). We compare SERS intensity and OCPV in both direct and remote illumination configurations. SERS spectra obtained by remote excitation are much more stable than those obtained through direct excitation when photon count rates are comparable. By statistical analysis of 33 devices, coupling efficiency of remote excitation is calculated to be around 10%, consistent with the simulated energy flow. Copyright © 2023, The Authors. All rights reserved.

关键词： Raman spectroscopy

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Scalable Crystal Structure Relaxation Using an Iteration-Free Deep Generative Model with Uncertainty Quantification

arXiv

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arXiv 2024年

作者： Yang, Ziduo Zhao, Yi-Ming Wang, Xian Liu, Xiaoqing Zhang, Xiuying Li, Yifan Lv, Qiujie Chen, Calvin Yu-Chian Shen, Lei Department of Mechanical Engineering National University of Singapore Singapore117575 Singapore Artificial Intelligence Medical Research Center School of Intelligent Systems Engineering Shenzhen Campus of Sun Yat-sen University Shenzhen518107 China Department of Physics National University of Singapore Singapore117551 Singapore -Preferred Program School of Electronic and Computer Engineering Peking University Shenzhen Graduate School Shenzhen518055 China State Key Laboratory of Chemical Oncogenomics School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen518055 China Department of Medical Research China Medical University Hospital Taichung40447 Taiwan Department of Bioinformatics and Medical Engineering Asia University Taichung41354 Taiwan Guangdong L-Med Biotechnology Co. Ltd. Guangdong Meizhou514699 China Research Institute Chongqing401123 China

In computational molecular and materials science, determining equilibrium structures is the crucial first step for accurate subsequent property calculations. However, the recent discovery of millions of new crystals and complex twisted structures has challenged traditional computational methods, both ab initio and machine-learning-based, due to their computationally intensive iterative processes. To address these scalability issues, here we introduce DeepRelax, a deep generative model capable of performing geometric crystal structure relaxation rapidly and without iterations. DeepRelax learns the equilibrium structural distribution, enabling it to predict relaxed structures directly from their unrelaxed ones. The ability to perform structural relaxation at the millisecond level per structure, combined with the scalability of parallel processing, makes DeepRelax particularly useful for large-scale virtual screening. We demonstrate DeepRelax's reliability and robustness by applying it to five diverse databases, including oxides, Materials Project, two-dimensional materials, van der Waals crystals, and crystals with point defects. DeepRelax consistently shows high accuracy and efficiency, validated by density functional theory calculations. Finally, we enhance its trustworthiness by integrating uncertainty quantification. This work significantly accelerates computational workflows, offering a robust and trustworthy machine-learning method for material discovery and advancing the application of AI for science. Code for DeepRelax is available at https://***/Shen-Group/DeepRelax. Copyright © 2024, The Authors. All rights reserved.

关键词： Point defects

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Measurement of Water Diffusion Coefficient in Cross-Linked Gelatins Using the Terahertz Time-Domain Spectroscopy Technique

Measurement of Water Diffusion Coefficient in Cross-Linked G...

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Conference on Lasers and Electro-Optics (CLEO)

作者： D. Walden D. Chakraborty J. Cheng A. Straksys A. Stirke W. CMA Melo A. Jukna I. Komissarov Roman Sobolewski Department of Physics and Astronomy University of Rochester Rochester New York USA Laboratory for Laser Energetics University of Rochester Rochester New York USA Materials Science Graduate Program University of Rochester Rochester New York USA State Research Institute Center for Physical Sciences & Technology Vilnius Lithuania Department of Physics Vilnius Gediminas Technical University Vilnius Lithuania Department of Electrical and Computer Engineering University of Rochester Rochester New York USA

A novel method has been developed to evaluate the water diffusion dynamics in gelatin-based gels, based on transient terahertz time-domain spectroscopy measurements. Such gels are widely used models for human skin.

ISBN: (纸本)9798350369311

关键词： Spectroscopy Measurement by laser beam Lasers and electrooptics Laser modes Skin Time-domain analysis Transient analysis Electro-optical waveguides

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E-payment for Jakarta Smart Public Transportation, Using the Point System for E-Commerce 2

E-payment for Jakarta Smart Public Transportation, Using the...

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2nd International Conference on computer, Science, engineering, and Technology, ICComSET 2019

作者： Anwar, Nizirwan Rasjidin, Roesfiansjah Najoan, Daniel Stephanus Rolando, Christopher Tamimmanar Warnars, Harco Leslie Hendric Spits Faculty of Computer Science Esa Unggul University Jakarta11510 Indonesia Faculty of Engineering Esa Unggul University Jakarta11510 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta11480 Indonesia

The ease of using transportation is one of the most critical things in the city with a significant population like Jakarta. The growth of the population in Jakarta is increased rapidly. The wage that Many transportations are causing a traffic jam in Jakarta. The government suggests that people use public transportation for their mobility. However, people choose to use their vehicles rather than public transportation. The main reason is that public transportation cannot guarantee the arriving time, whether it is on time or not. Many people move on to online transportation services. However, the massive growth of online transportation is still a contradiction as public transportation. People in Jakarta need faster mobility to go. This research is trying to make a system for public transport without any delay and hard to use it. This problem can be solved by building a new system. This system required e-wallet for payment in public transportation. This E-Wallet will search the possible route from the nearest location to the destination - only the public transport where there is a station that can use it. By using QR-Code generated by e-wallet on the mobile phone, people can scan it directly to a machine located in the station. This method will make a transaction faster than ever. Moreover, people can enjoy another feature like cashback and redeem the prize by a point system. In this era, e-commerce is dominating the market for purchasing something. This is also the attraction of the system. This system is also required excellent facilities from the government so that people can enjoy it. © Published under licence by IOP Publishing Ltd.

关键词： Traffic congestion

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Protomon: A Multimode Qubit in the Fluxonium Molecule

arXiv

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arXiv 2024年

作者： Kumar, Shashwat You, Xinyuan Croot, Xanthe Zhao, Tianpu Chen, Danyang Sussman, Sara Premkumar, Anjali Bryon, Jacob Koch, Jens Houck, Andrew A. Department of Electrical and Computer Engineering Princeton University PrincetonNJ08544 United States Northwestern–Fermilab Center for Applied Physics and Superconducting Technologies Northwestern University EvanstonIL60208 United States Graduate Program in Applied Physics Northwestern University EvanstonIL60208 United States Department of Physics Princeton University PrincetonNJ08544 United States Department of Physics and Astronomy Northwestern University EvanstonIL60208 United States

Qubits that are intrinsically insensitive to depolarization and dephasing errors promise to significantly reduce the overhead of fault-tolerant quantum computing. At their optimal operating points, the logical states of these qubits exhibit both exponentially suppressed matrix elements and sweet spots in energy dispersion, rendering the qubits immune to depolarization and dephasing, respectively. We introduce a multimode qubit, the protomon, encoded in a fluxonium molecule circuit. Compared to the closely related 0–π qubit, the protomon offers several advantages in theory: resilience to circuit parameter disorder, minimal dephasing from intrinsic harmonic modes, and no dependence on static offset charge. As a proof of concept, we realize four protomon qubits. By tuning the qubits to various operating points identified with calibrated two-tone spectroscopy, we measure depolarization times ranging from 64 to 73 µs and dephasing times between 0.2 to 0.5 µs for one selected qubit. The discrepancy between the relatively short measured coherence times and theoretical predictions is not fully understood. This calls for future studies investigating the limiting noise factors, informing the direction for improving coherence times of the protomon qubit. © 2024, CC BY.

关键词： Qubits

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Reduction of interface defects in gate-recessed GaN HEMTs by neutral beam etching

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Materials Today Advances 2024年 23卷

作者： Yu, Chia Hao Chiang, Wei Hsiang Chen, Yi-Ho Samukawa, Seiji Wuu, Dong Sing Chung, Chin-Han Hsiao, Ching-Lien Horng, Ray Hua Institute of Electronics National Yang Ming Chiao Tung University Department of Materials Science and Engineering National Chung Hsing University Graduate Degree Program of College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Institute of Comunications Engineering National Yang Ming Chiao Tung University Department of Applied Materials and Optoelectronic Engineering National Chi Nan University International College of Semiconductor Technology National Yang Ming Chiao Tung University Thin Film Physics Division Department of Physics Chemistry and Biology (IFM) Linköping University

This study investigates and compares the impact of different etching techniques on the fabrication of GaN high electron mobility transistors (HEMTs) between the inductively coupled plasma reactive ion etching (ICP-RIE) and the neutral beam etching (NBE) for the gate recess. By conducting direct current analysis, it was found that devices manufactured using the NBE exhibited superior electrical performance as compared with those produced using the ICP-RIE. These enhanced electrical characteristics include a transconductance of up to 100.4 mS/mm, a threshold voltage (V_th) of −2.3 V, an on/off current ratio of 1.1 × 10⁹, a subthreshold swing (S.S.) of 99.63 mV/dec, and a remarkably low gate leakage current. Additionally, we noted varying degrees of hysteresis in the I–V characteristics were related to process disparities possibly leading to interface defects. Multi-frequency capacitance-voltage (C–V) measurements were used to identify the interface defects at the oxide/AlGaN interface of the gate. The results revealed that devices fabricated using the NBE exhibited a lower interface defect density as compared with those fabricated using the ICP-RIE, thereby elucidating the reduced hysteresis observed in the I–V characteristics. These findings indicated the significant advantages of the NBE process in the fabrication of GaN HEMTs. © 2024 The Authors

关键词： GaN HEMTs Gate recess Interface defects Multi-frequency C–V Neutral beam etching

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Personnel System Development with Integrated Military Education Information System (MEIS) in Supporting the Personnel Position and Career 7

Personnel System Development with Integrated Military Educat...

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7th International Conference on ICT for Smart Society, ICISS 2020

作者： Setyaningrum, Leli Supangkat, Suhono H. Warnars, Harco Leslie Hendric Spits Abraham, Juneman Abdurachman, Edi Bina Nusantara University Doctorate Program of Computer Science Jakata Barat11530 Indonesia Institut Teknologi Bandung School of Electrical Engineering and Informatics Bandung40132 Indonesia Nusantara University Graduate Program Doctor of Computer Science Bina Computer Science Department BINUS Jakarta11530 Indonesia Bina Nusantara University BINUS Faculty of Humanities Psychology Department Jakarta11480 Indonesia

ISBN: (纸本)9781665404228

Personnel and education data very important for organizations, including the military. All data related to military personnel will give effect positions and careers in the military field. The integration of personnel and education data can assist in processing and decision making. An analysis is needed so that the developed system can be useful for the long term. Analysis with IT balanced scorecard and COBIT® 2019, will be able to help and fill the gaps in the existing system based on the objectives of the military organization itself. It is shown that the domains BAI05 (Managed Organizational Change) and DSS02 (Managed Service Requests and Incidents) are still not being implemented well. The system developed will have the features and capabilities to support the organization in achieving its goals, including in the field of staffing and education. Besides, it provides convenience in making decisions in terms of positions related to personnel careers. © 2020 IEEE.

关键词： Decision making

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Terahertz spin dynamics in rare-earth orthoferrites

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Photonics Insights 2022年第2期1卷 1-56页

作者： Xinwei Li Dasom Kim Yincheng Liu Junichiro Kono Department of Physics California Institute of TechnologyPasadenaUSA Department of Electrical and Computer Engineering Rice UniversityHoustonUSA Applied Physics Graduate Program Smalley-Curl InstituteRice UniversityHoustonUSA Department of Physics and Astronomy Rice UniversityHoustonUSA Department of Materials Science and NanoEngineering Rice UniversityHoustonUSA

Recent interest in developing fast spintronic devices and laser-controllable magnetic solids has sparked tremendous experimental and theoretical efforts to understand and manipulate ultrafast dynamics in *** of spin dynamics in the terahertz(THz)frequency range are particularly important for elucidating microscopic pathways toward novel device ***,we review THz phenomena related to spin dynamics in rare-earth orthoferrites,a class of materials promising for antiferromagnetic *** expand this topic into a description of four key elements.(1)We start by describing THz spectroscopy of spin excitations for probing magnetic phase transitions in thermal *** acoustic magnons are useful indicators of spin reorientation transitions,electromagnons that arise from dynamic magnetoelectric couplings serve as a signature of inversion-symmetry-breaking phases at low temperatures.(2)We then review the strong laser driving scenario,where the system is excited far from equilibrium and thereby subject to modifications to the free-energy *** pathways for ultrafast laser manipulation of magnetic order are discussed.(3)Furthermore,we review a variety of protocols to manipulate coherent THz magnons in time and space,which are useful capabilities for antiferromagnetic spintronic applications.(4)Finally,new insights into the connection between dynamic magnetic coupling in condensed matter and the Dicke superradiant phase transition in quantum optics are *** presenting a review on an array of THz spin phenomena occurring in a single class of materials,we hope to trigger interdisciplinary efforts that actively seek connections between subfields of spintronics,which will facilitate the invention of new protocols of active spin control and quantum phase engineering.

关键词： terahertz spin dynamics magnetism orthoferrite ultrafast spectroscopy magneto-optics

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