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Galactic transient sources with the Cherenkov Telescope Array Observatory

Monthly Notices of the Royal Astronomical Society 2025年第1期540卷 205–238页

作者： Abe, K Abe, S Abhir, J Abhishek, A Acero, F Acharyya, A Adam, R Aguasca-Cabot, A Agudo, I Aguirre-Santaella, A Alfaro, J Alfaro, R Alvarez-Crespo, N Alves Batista, R Amans, J-P Amato, E Ambrosi, G Ambrosino, F Angüner, E O Antonelli, L A Aramo, C Arcaro, C Arnesen, T T H Asano, K Ascasibar, Y Aschersleben, J Ashkar, H Augusto Stuani, L Baack, D Backes, M Balazs, C Balbo, M Baquero Larriva, A Barbosa Martins, V Barres de Almeida, U Barrio, J A Barrios-Jiménez, L Batković, I Batzofin, R Baxter, J Becerra González, J Becker Tjus, J Belmont, R Benbow, W Bernete, J Bernlöhr, K Berti, A Bertucci, B Beshley, V Bhattacharjee, P Bhattacharyya, S Bigongiari, C Bissaldi, E Blanch, O Blazek, J Bocchino, F Boisson, C Bolmont, J Bonnoli, G Bonollo, A Bordas, P Bosnjak, Z Bottacini, E Böttcher, M Bradascio, F Bronzini, E Brown, A M Brunelli, G Bulgarelli, A Burelli, I Burger-Scheidlin, C Burmistrov, L Burton, M Buscemi, M Cailleux, J Campoy-Ordaz, A Cantlay, B K Capasso, G Caproni, A Capuzzo-Dolcetta, R Caraveo, P Caroff, S Carosi, A Carosi, R Carquin, E Carrasco, M-S Cascone, E Cassol, F Castaldini, L Castrejon, N Castro-Tirado, A J Cerasole, D Ceribella, G Cerruti, M Chadwick, P M Chaty, S Chen, A W Chernyakova, M Chiavassa, A Chudoba, J Chytka, L Cicciari, G M Cifuentes, A Coimbra Araujo, C H Colapietro, M Conforti, V Contreras, J L Cortina, J Costa, A Costantini, H Cotter, G Cristofari, P Cuevas, O Curtis-Ginsberg, Z D’Aì, A D’Amico, G D’Ammando, F Dai, S Dazzi, F de Bony de Lavergne, M De Caprio, V De Cesare, G De Frondat Laadim, F de Gouveia Dal Pino, E M De Lotto, B De Lucia, M de Martino, D de Menezes, R de Naurois, M de Ona Wilhelmi, E de Souza, V del Peral, L del Valle, M V Delgado, C Dell’aiera, M Della Valle, M della Volpe, D Depaoli, D Devin, J Di Girolamo, T Di Piano, A Di Pierro, F Di Tria, R Di Venere, L Diebold, S Dignam, C Dima, R Dinesh, A Djuvsland, J Dominik, R M Dominis Prester, D Donini, A Dorner, D Dörner, J Doro, M Dubos, C Ducci, L Dwarkadas, V V Ebr, J Eckner, C Egberts, K Einecke, S Elsässer, D Emery Department of Physics Tokai University 4-1-1 Kita-Kaname Hiratsuka Kanagawa 259-1292 Japan Institute for Cosmic Ray Research University of Tokyo 5-1-5 Kashiwa-no-ha Kashiwa Chiba 277-8582 Japan ETH Zürich Institute for Particle Physics and Astrophysics Otto-Stern-Weg 5 CH-8093 Zürich Switzerland INFN and Università degli Studi di Siena Dipartimento di Scienze Fisiche della Terra e dell’Ambiente (DSFTA) Sezione di Fisica Via Roma 56 I-53100 Siena Italy Université Paris-Saclay Université Paris Cité CEA CNRS AIM F-91191 Gif-sur-Yvette Cedex France FSLAC IRL 2009 CNRS/IAC E-38205 La Laguna Tenerife Spain University of Alabama Tuscaloosa Department of Physics and Astronomy Gallalee Hall Box 870324 Tuscaloosa AL 35487-0324 USA Université Côte d’Azur Observatoire de la Côte d’Azur CNRS Laboratoire Lagrange UF 06304 Nice France Laboratoire Leprince-Ringuet CNRS/IN2P3 École Polytechnique Institut Polytechnique de Paris F-91120 Palaiseau France Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Martí i Franquès 1 E-08028 Barcelona Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n E-18008 Granada Spain Institute for Computational Cosmology and Department of Physics Durham University South Road Durham DH1 3LE UK Pontificia Universidad Católica de Chile Av. Libertador Bernardo O’Higgins 340 8331150 Santiago Chile Universidad Nacional Autónoma de México Delegación Coyoacán 04510 Ciudad de México Mexico IPARCOS-UCM Instituto de Física de Partículas y del Cosmos and EMFTEL Department Universidad Complutense de Madrid E-28040 Madrid Spain Instituto de Física Teórica UAM/CSIC and Departamento de Física Teórica Universidad Autónoma de Madrid c/ Nicolás Cabrera 13-15 Campus de Cantoblanco UAM E-28049 Madrid Spain LUTH GEPI and LERMA Observatoire de Paris Université PSL Université Paris Cité CNRS 5 place Jules Janssen F-92190 Meudon France INAF – Osservatorio

A wide variety of Galactic sources show transient emission at soft and hard X-ray energies: low- and high-mass X-ray binaries containing compact objects, isolated neutron stars exhibiting extreme variability as magnetars as well as pulsar-wind nebulae. Although most of them can show emission up to MeV and/or GeV energies, many have not yet been detected in the TeV domain by Imaging Atmospheric Cherenkov Telescopes. In this paper, we explore the feasibility of detecting new Galactic transients with the Cherenkov Telescope Array Observatory (CTAO) and the prospects for studying them with Target of Opportunity observations. We show that CTAO will likely detect new sources in the TeV regime, such as the massive microquasars in the Cygnus region, low-mass X-ray binaries with low-viewing angle, flaring emission from the Crab pulsar-wind nebula or other novae explosions, among others. Since some of these sources could also exhibit emission at larger time-scales, we additionally test their detectability at longer exposures. We finally discuss the multiwavelength synergies with other instruments and large astronomical facilities.

关键词： binaries: general stars: magnetars novae cataclysmic variables pulsars: general gamma-rays: general

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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

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NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

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Distributed multi-robot coordination for dynamic perimeter surveillance in uncertain environments

Distributed multi-robot coordination for dynamic perimeter s...

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IEEE International Conference on Robotics and Automation (ICRA)

作者： Alexander Jahn Reza Javanmard Alitappeh David Saldaña Luciano C. A. Pimenta Andre G. Santos Mario F. M. Campos Graduate Program in Electrical Engineering (PPGEE) National Institute of Science and Technology for Cooperative Autonomous Systems Applied to Security and Environment Departamento de Informatica Universidade Federal de Vicosa Computer Science Department Universidade Federal de Minas Gerais Universidade Federal de Minas Gerais Belo Horizonte MG BR

In this work, multiple robots circulate around the boundary of a desired region in order to create a virtual fence. The aim of the this fence is to avoid internal or external agents crossing through the delimited area. In this paper, we propose a distributed technique that allows a team of robots to plan the deformation of the boundary shape in order to escort the safe region from one place to a goal. Our proposal is composed of two parts. First, we present a distributed planning method for the dynamic boundary. We model the resulting plan as a twice differentiable function. Second, we use the obtained function to guide the robot team, where every member uses only local information for the controller. The robots distribute themselves along the time-varying perimeter and patrol around it. We show in simulation how the robots behave in partially/totally unknown environments with static obstacles.

关键词： Shape Robot kinematics Trajectory Planning Robot sensing systems Dynamics

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BHEL Smart Wall Blowing System: New Product Development in Manufacturing Industry

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Vikalpa 2021年第4期45卷 240 - 249页

作者： Abhishek Kumar R. Dhanuskodi R. Kaliappan K. Nandakumar Abhishek Kumar teaches design philosophies at Anant National University Ahmedabad. He earned his Ph.D in Management from Pondicherry University. He is an Economics graduate from Calcutta University and MBA from BIM Trichy. He has published more than 20 articles in reputed international journals has authored two books written articles and columns for newspapers and is quoted on issues related to leadership and marketing by various media platforms. His research work comprises construction of brand personality scale for media aesthetics and phenomenological design. His recent publications are on philosophy of a photograph hermeneutic reality of product and on philosophy of intimate spaces. R. Dhanuskodi has nearly 40 years of R&D experience at BHEL India in technical areas applicable for thermal power plants. He is a life member of The Institution of Engineers (India) and The Combustion Institute. He has won two BHEL’s Excel awards under the best author category for technical papers. He has visited France Netherlands and Germany under Indo-Europe Clean Coal Development Program. He has guided 42 UG PG and PhD project works. He holds 11 patents 40 copyrights and 2 design registrations. He has presented papers in 20 conferences and published in 10 national and international journals. R. Kaliappan completed his bachelors in electrical and electronics engineering and Masters in Computer Science. He has 36 years of research experience in different fields of power generation and power plant subsystems such as heat transfer studies on boiler circulation efficiency improvements of boiler subsystems product improvements/ enhancements and setting up test facilities for research studies. He has published a number of technical papers on MHD power generation and heat transfer studies in various national and international journals. He has more than 25 patents and copyrights on products development related to power boilers. He has won BHEL’S gold medal for product development for Smart Wall Blowing system. K. Nandakumar

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Analysis of plant pattern using water balance and cimogram based on oldeman climate type

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IOP Conference Series: Earth and Environmental science 2018年第1期195卷

作者： R E Caraka M Tahmid R M Putra A Iskandar M A Mauludin Hermansah N E Goldameir H Rohayani B Pardamean Bioinformatics and Data Science Research Center (BDSRC) Bina Nusantara University Jakarta Indonesia 11480 Indonesia Agency for Meteorology Climatology and Geophysics Indonesia Informatics Engineering STMIK AKBA Makassar Laboratory of Sociology and Extension Universitas Padjadjaran Universitas Riau Kepulauan Riau University Universitas Adiwangsa Jambi Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480

The transfer of land has an impact on the decreasing of the agricultural land area, so it is necessary to plan the right cropping pattern as an effort to increase the productivity of agricultural cultivation. Also, Climate is one of the factors influencing the determination of cropping pattern in a region. Analysis of climatic characteristics in the determination of cropping pattern not only based on oldeman climatic classification. At the same time, the study of groundwater availability for plants and climogram of climatic elements is needed in determining planting schedule which is suitable for planting and determination of irrigation water supply, either the right amount of time. This study aims to identify and build spatial of the oldeman climate classification. It also determines the cropping pattern for seasonal crops based on the calculation of water balance and climogram (rainfall and air temperature) in each type of climate oldeman district of Cirebon and surrounding areas. Data used monthly rainfall data period 1981-2010 from BMKG Jatiwangi station and air temperature data, plant coefficient and the base map of Cirebon region. The analysis method includes classification of Oldeman climate type, spatial data processing, water balance calculation by Thorntwaite & Matter method and making climogram (rainfall and temperature) with: k = p0 + p1/FC; p0 = 1.000412351; p1 = -1.073807306 and determination of planting pattern of each type of oldeman

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Ambient-pressure CVD of graphene on low-index Ni surfaces using methane: A combined experimental and first-principles study

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Physical Review Materials 2018年第7期2卷 073404-073404页

作者： Daniela L. Mafra Jimena A. Olmos-Asar Fabio R. Negreiros Alfonso Reina Ki Kang Kim Mildred S. Dresselhaus Jing Kong Gary J. Mankey Paulo T. Araujo Department of Electrical Engineering and Computer Sciences Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Centro de Ciências Naturais e Humanas Universidade Federal do ABC Santo André 09210-580 SP Brazil INFIQC CONICET Departamento de Química Teórcia y Computacional Facultad de Ciencias Químicas Universidad Nacional de Córdoba X5000HUA Argentina Department of Materials Science and Engineering Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Department of Energy and Materials Engineering Dongguk University-Seoul Seoul 04620 Republic of Korea Department of Physics Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Department of Physics and Astronomy The University of Alabama Tuscaloosa Alabama 35487 USA Center for Materials for Information Technology (MINT Center) The University of Alabama Tuscaloosa Alabama 35401 USA Natural Sciences Institute Graduate Program in Physics - Federal University of Para Belem PA 66075-110 Brazil

The growth of large area single-layer graphene (1-LG) is studied using ambient pressure chemical vapor deposition on single-crystal Ni(111), Ni(110), and Ni(100). By varying both the furnace temperature in the range of 800–1100 °C and the gas flow through the growth chamber, uniform, high-quality 1-LG is obtained for Ni(111) and Ni(110) single crystals and for Ni(100) thin films. Surprisingly, only multilayer graphene growth could be obtained for single-crystal Ni(100). The experimental results are analyzed to determine the optimum combination of temperature and gas flow. Characterization with optical microscopy, Raman spectroscopy, and optical transmission support our findings. Density-functional theory calculations are performed to determine the energy barriers for diffusion, segregation, and adsorption, and model the kinetic pathways for formation of different carbon structures on the low-index surfaces of Ni.

关键词： Growth Synthesis 2-dimensional systems Carbon-based materials Atomic force microscopy Chemical vapor deposition Density functional calculations Density functional theory Raman spectroscopy

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Investigation of the visual attention role in clinical bioethics decision-making using machine learning algorithms

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Procedia computer science 2017年 108卷 1165-1174页

作者： Daniel L. Fernandes Rodrigo Siqueira-Batista Andréia P. Gomes Camila R. Souza Israel T. da Costa Felippe da S.L. Cardoso João V. de Assis Gustavo H.L. Caetano Fabio R. Cerqueira Graduate Program in Computer Science Universidade Federal de Viçosa Minas Gerais Brazil Department of Medicine and Nursing Universidade Federal de Viçosa Minas Gerais Brazil Department of Physical Education Universidade Federal de Viçosa Minas Gerais Brazil Department of Production Engineering Universidade Federal Fluminense Rio de Janeiro Brazil

This study proposes the use of a computational approach based on machine learning (ML) algorithms to build predictive models using eye tracking data. Our intention is to provide results that may support the study of medical investigation in the decision-making process in clinical bioethics, particularly in this work, in cases of euthanasia. The data used in the approach were collected from 75 students of the nursing undergraduate course using an eye tracker. The available data were processed through feature selection methods, and were later used to create models capable of predicting the euthanasia decision through ML algorithms. Statistical experiments showed that the predictive model resultant from the multilayer perceptron (MLP) algorithm led to the best performance compared with the other tested algorithms, presenting an accuracy of 90.7% and a mean area under the ROC curve of 0.90. Interesting knowledge (patterns and rules) for the studied bioethical decision-making was extracted using simulations with MLP models and inspecting the obtained decision-tree rules. The good performance shown by the obtained MLP predictive model demonstrates that the proposed investigation approach may be used to test scientific hypotheses related to visual attention and decision-making.

关键词： Visual attention Decision-making in bioethics Mobile eye tracking Machine learning in medicine

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Euclid: Early Release Observations – A preview of the Euclid era through a galaxy cluster magnifying lens

arXiv

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arXiv 2024年

作者： Atek, Hakim Gavazzi, R. Weaver, J.R. Diego, J.M. Schrabback, T. Hatch, N.A. Aghanim, N. Dole, H. Hartley, W.G. Taamoli, S. Congedo, G. Jimenez-Teja, Y. Cuillandre, J.-C. Bañados, E. Belladitta, S. Bowler, R.A.A. Franco, M. Jauzac, M. Mahler, G. Richard, J. Rocci, P.-F. Serjeant, S. Toft, S. Abriola, D. Bergamini, P. Biviano, A. Dimauro, P. Ezziati, M. Golden-Marx, J.B. Grillo, C. Hughes, A.C.N. Kang, Y. Kneib, J.-P. Lombardi, M. Mamon, G.A. McPartland, C.J.R. Meneghetti, M. Miyatake, H. Montes, M. Mortlock, D.J. Oesch, P.A. Okabe, N. Rosati, P. Taylor, A.N. Tarsitano, F. Weller, J. Kluge, M. Laureijs, R. Paltani, S. Saifollahi, T. Schirmer, M. Stone, C. Mora, A. Altieri, B. Amara, A. Andreon, S. Auricchio, N. Baldi, M. Balestra, A. Bardelli, S. Basset, A. Bender, R. Bodendorf, C. Bonino, D. Branchini, E. Brescia, M. Brinchmann, J. Camera, S. Candini, G.P. Capobianco, V. Carbone, C. Cardone, V.F. Carretero, J. Casas, S. Castander, F.J. Castellano, M. Cavuoti, S. Cimatti, A. Conselice, C.J. Conversi, L. Copin, Y. Corcione, L. Courbin, F. Courtois, H.M. Da Silva, A. Degaudenzi, H. Di Giorgio, A.M. Dinis, J. Douspis, M. Dubath, F. Dupac, X. Dusini, S. Ealet, A. Farina, M. Farrens, S. Ferriol, S. Fotopoulou, S. Frailis, M. Franceschi, E. Galeotta, S. Gillard, W. Gillis, B. Giocoli, C. Gómez-Alvarez, P. Grazian, A. Grupp, F. Guzzo, L. Hailey, M. Haugan, S.V.H. Hoar, J. Hoekstra, H. Holliman, M.S. Holmes, W. Hook, I. Hormuth, F. Hornstrup, A. Hudelot, P. Jahnke, K. Jhabvala, M. Keihänen, E. Kermiche, S. Kiessling, A. Kitching, T. Kohley, R. Kubik, B. Kuijken, K. Kümmel, M. Kunz, M. Kurki-Suonio, H. Lahav, O. Le Mignant, D. Ligori, S. Lilje, P.B. Lindholm, V. Lloro, I. Maino, D. Maiorano, E. Mansutti, O. Marggraf, O. Markovic, K. Martinet, N. Marulli, F. Massey, R. Maurogordato, S. McCracken, H.J. Mei, S. Mellier, Y. Merlin, E. Meylan, G. Moresco, M. Moscardini, L. Nakajima, R. Nichol, R.C. Institut d’Astrophysique de Paris UMR 7095 CNRS Sorbonne Université 98 bis boulevard Arago Paris75014 France Aix-Marseille Université CNRS CNES LAM Marseille France Department of Astronomy University of Massachusetts AmherstMA01003 United States Instituto de Física de Cantabria Edificio Juan Jordá Avenida de los Castros Santander39005 Spain Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstr. 25/8 Innsbruck6020 Austria School of Physics and Astronomy University of Nottingham University Park NottinghamNG7 2RD United Kingdom Université Paris-Saclay CNRS Institut d’astrophysique spatiale Orsay91405 France Department of Astronomy University of Geneva ch. d’Ecogia 16 Versoix1290 Switzerland Physics and Astronomy Department University of California 900 University Ave. RiversideCA92521 United States Institute for Astronomy University of Edinburgh Royal Observatory Blackford Hill EdinburghEH9 3HJ United Kingdom Instituto de Astrofísica de Andalucía CSIC Glorieta de la Astronomía Granada18080 Spain Observatorio Nacional Rua General Jose Cristino 77-Bairro Imperial de Sao Cristovao Rio de Janeiro20921-400 Brazil Université Paris-Saclay Université Paris Cité CEA CNRS AIM Gif-sur-Yvette91191 France Max-Planck-Institut für Astronomie Königstuhl 17 Heidelberg69117 Germany INAF-Osservatorio di Astrofisica e Scienza dello Spazio di Bologna Via Piero Gobetti 93/3 Bologna40129 Italy Jodrell Bank Centre for Astrophysics Department of Physics and Astronomy University of Manchester Oxford Road ManchesterM13 9PL United Kingdom The University of Texas at Austin AustinTX78712 United States Department of Physics Centre for Extragalactic Astronomy Durham University South Road DH1 3LE United Kingdom Department of Physics Institute for Computational Cosmology Durham University South Road DH1 3LE United Kingdom Astrophysics Research Centre University of KwaZulu-Natal Westville Campus Durban4041 South Africa School of

We present the first analysis of the Euclid Early Release Observations (ERO) program that targets fields around two lensing clusters, Abell 2390 and Abell 2764. We use VIS and NISP imaging to produce photometric catalogs for a total of ∼ 500 000 objects. The imaging data reach a 5 σ typical depth in the range 25.1–25.4 AB in the NISP bands, and 27.1–27.3 AB in the VIS band. Using the Lyman-break method in combination with photometric redshifts, we search for high-redshift galaxies. We identify 30 Lyman-break galaxy (LBG) candidates at z > 6 and 139 extremely red sources (ERSs), most likely at lower redshift. The deeper VIS imaging compared to NISP means we can routinely identify high-redshift Lyman breaks of the order of 3 magnitudes, which reduces contamination by brown dwarf stars and low-redshift galaxies. The difficulty of spatially resolving most of these sources in 0′′ . 3 pix−1 imaging makes the distinction between galaxies and quasars more challenging. Spectroscopic followup campaigns of such bright sources will help constrain both the bright end of the ultraviolet galaxy luminosity function and the quasar luminosity function at z > 6, and constrain the physical nature of these objects. Additionally, we have performed a combined strong lensing and weak lensing analysis of A2390, and demonstrate how Euclid will contribute to better constraining the virial mass of galaxy clusters. From these data, we also identify optical and near-infrared counterparts of known z > 0.6 clusters, which exhibit strong lensing features, establishing the ability of Euclid to characterize high-redshift clusters. Finally, we provide a glimpse of Euclid’s ability to map the intracluster light out to larger radii than current facilities, enabling a better understanding of the cluster assembly history and mapping of the dark matter distribution. This initial dataset illustrates the diverse spectrum of legacy science that will be enabled by the Euclid survey. © 2024, CC BY.

关键词： Galaxies

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Applying the MVC EA-IRPM to reporting-guidelines in medicine: A strategy that is a web system

Applying the MVC EA-IRPM to reporting-guidelines in medicine...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Patrick Letouze J. I. M. de Souza Valéria Martins Silva Glaubos Climaco F. B. Chagas Joao Y. Ishihara Faculty of Computer Science Universidade Federal do Tocantins Palmas Brazil Universidade Federal do Tocantins Palmas TO BR Graduate Program of Systems' Engineering and Computation Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Department of Informatics Universidade Federal do Maranh/ ao - UFMA Faculty of Computer Science Faculdade Pitagoras Imperatriz Imperatriz Brazil Faculty of Electrical Engineering Universidade de Brasília Brasília Brazil

ISBN: (纸本)9781509041800

Reporting-Guidelines in Medicine play an important role in promoting the quality of reports in health-related research. For instance, a poorly reported research may induce misinterpretation and inappropriate clinical settings. Basically, three major issues regarding Reporting-Guidelines in Medicine has to be addressed: (1) the existence of lots of reporting guidelines covering a broad spectrum of medical research increases the difficulties when reporting a medical research because it may not be clear which guidelines are applicable, or if all related guidelines are considered; (2) most guideline developers have not described how their guidance was developed, consequently tracking guidelines and features for evaluation, or even for correcting, may be not possible; (3) few guideline developers have evaluated the effectiveness of their guidance, then the real value that the guideline brings to reporting the research is not assured. Hence, we propose a solution to these three issues based on the Model-View-Controller Evolutionary Acquisition Interdisciplinary Research Project Management (MVC EA-IRPM) that is simultaneously a strategy and a web system for the development and management of reporting guidelines.

关键词： Guidelines Project management Planning Adaptation models Phase measurement Systems architecture Systematics

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Genetic variation of somaclonal mutants from the 8th generation of Pekalongan accession rodent tuber (typhonium flagelliforme lodd.) based on RAPD-PCR analysis

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IOP Conference Series: Earth and Environmental science 2018年第1期195卷

作者： Ragapadmi Purnamaningsih Nesti Fronika Sianipar Khoirunnisa Assidqi Harco Leslie Hendric Spits Warnars Indonesia Center for Agricultural Biotechnology and Genetic Resources Research and Development (BB-Biogen) Bogor 16111 Indonesia Food Technology Department Faculty of Engineering Bina Nusantara University Jakarta Indonesia 11480 Research Interest Group Food Biotechnology Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program – Doctor of Computer Science Bina Nusantara University Jakarta 11480 Indonesia

Rodent tuber is a potential plant which can be developed as an anticancer drug. The rodent tuber plant has a low anticancer compound which does not have an economic value to be utilized on an industrial scale, particularly to explore as an anticancer drug. The material plant was used 30 clones of Rodent Tuber Pekalongan to increase its bioactive compounds using a combination of in vitro culture with gamma-ray irradiation. The selection process has been done until the 8th generation and obtained 14 somaclonal mutants that have higher bioactive compounds than control plant (non-mutant). This study aimed to analyze the genetic variation of 14 somaclonal mutants of rodent tuber using RAPD with 14 primers. The results were produced 513 total bands with the size of 200-5000 bp and 380 polymorphic bands between somaclonal mutants. OPB-18 primer produced the most polymorphic bands and five specific polymorphic bands of 1336 bp, 1070 bp, 901 bp, 861 bp and 728 bp in the somaclonal mutant M23 (20-4-2-1-1-1). OPD-20 primer produced seven specific polymorphic bands of 1574 bp, 1557 bp, 1501 bp, 1496 bp, 1234 bp, 1229 bp and 1086 bp in the M23 somaclonal mutant. The phylogenetic analysis showed that there were two main groups with the coefficient similarity between 0.77 and 0.83. The highest genetic variation obtained was found in the M23 somaclonal mutant with a genetic difference of 23% compared with control. There are five somaclonal mutants (M24, M22, M21, M16, M14) that have a genetic variation of up to 22% over the control. This study shows that OPB-18 and OPD-20 primers were efficient in detecting somaclonal mutant variants.

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