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8th International Conference on Intelligent Environments, IE 2012

作者： Jauregui-Ortiz, Salvador Siller, Mario Ramos, Felix Scalabrin, Edson Electrical Engineering and Computer Science Department Center of Research and Advanced Studies Guadalajara Jalisco Mexico Graduate Program in Computer Science Pontifical Catholic University Parana Brazil Curitiba Parana Brazil

ISBN: (纸本)9780769547411

As far as we know, there is not a Node Localization Algorithm (NLA) that presents the same accuracy for all possible scenarios. We believe that a NLA should be able to interpret the dynamic information of the environment. In this sense, simple NLAs are rather focused and might perform well for specific scenarios and applications. Therefore, information fusion and context awareness seems to be an appropriate approach to address this issue. We propose the Smart Environmental Architecture for Node Localization (SEA-NL), which is composed by two main elements: (i) the Smart Beacon Nodes (SBNs) and (ii) the Logical Position of Nodes (LPN). In (i) the obstruction level indicator is estimated and can improve the estimation of distances among nodes. In (ii) environment information and a one to one relation between a node and an object are used and can also improve location estimation. Via simulation, our architecture was tested indoors and outdoors considering three localization algorithms: the Weighed Centroid Localization (WCL), the Centroid Localization, and the Triangular Centroid Localization. Finally, we present an accuracy comparison among NLAs used in isolated way, and by using the SBNs, the LPN, and the SEA-NL, where our architecture improves WCL up to ~30.88%. © 2012 IEEE.

关键词： Information fusion

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Hybrid clutter canceler with feedback guided predicative filtering on a heterogeneous parallel processing system

Hybrid clutter canceler with feedback guided predicative fil...

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International Waveform Diversity and Design Conference, WDD 2012

作者： Brinkhus, Jeffrey M. Jezak, Joseph A. Berdanier, Charles Levitan, Steven P. Chiarulli, Donald M. Electical and Computer Engineering University of Pittsburgh United States Computer Engineering Graduate Program University of Pittsburgh United States Electrical Engineering Wright State University United States Computer Science Department University of Pittsburgh United States

ISBN: (纸本)9781509005987

In this paper we describe a novel clutter cancellation platform based on a two stage approach that combines a feedback guided predictive front-end hybrid clutter canceller with high performance back-end filtering and target detection. The front-end architecture is based on an FPGA implementation of a Kalman filter that predicts target locations in real time and removes the target signals from the incoming data prior to hybrid cancellation. The back-end is user configurable and exploits high performance GPU and multi-core parallel hardware to simultaneously compute multiple clutter suppression and target detection algorithms coupled to an intelligent selection strategy for selecting the most accurate result. These target locations are fed back to the FPGA Kalman filter periodically to update the target predictions. © 2012 IEEE.

关键词： Kalman filters

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Initial explorations on using CRFs for turkish named entity recognition

Initial explorations on using CRFs for turkish named entity ...

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24th International Conference on Computational Linguistics, COLING 2012

作者： Şseker, Gökhan Akin Eryǐgit, Güļsen ITU Informatics Institute Graduate Program in Computer Science Istanbul Technical University Istanbul 34469 Turkey Department of Computer Engineering Istanbul Technical University Istanbul 34469 Turkey

This paper reports the highest results (95% in MUC and 92% in CoNLL metric) in the literature for Turkish named entity recognition;more specifically for the task of detecting person, location and organization entities in general news texts. We give an in depth analysis of the previous reported results and make comparisons with them whenever possible. We use conditional random fields (CRFs) as our statistical model. The paper presents initial explorations on the usage of rich morphological structure of the Turkish language as features to CRFs together with the use of some basic and generative gazetteers. © 2012 The COLING.

关键词： Random processes

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Clinical "MUTATOME" Of Myelodysplastic Syndrome;Comparison To Primary Acute Myelogenous Leukemia

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BLOOD 2013年第21期122卷 518-518页

作者： Makishima, Hideki LaFramboise, Thomas Przychodzen, Bartlomiej P. Yoshida, Kenichi Ruffalo, Matthew Gomez-Segui, Ines Husseinzadeh, Holleh D. Shiraishi, Yuichi Sanada, Masashi Nagata, Yasunobu Sato, Yusuke Sato-Otsubo, Aiko Chiba, Kenichi Tanaka, Hiroko Nakamaki, Tsuyoshi Hofmann, Wolf-Karsten Miyawaki, Shuichi Shih, Lee-Yung Chiba, Shigeru Miyano, Satoru Hosono, Naoko Polprasert, Chantana Thota, Swapna Dienes, Brittney Guinta, Kathryn M. Sauntharatajah, Yogen Sekeres, Mikkael A. Ogawa, Seishi Maciejewski, Jaroslaw P. Translational Hematology and Oncology Research Cleveland Clinic Taussig Cancer Institute Cleveland OH USA Department of Electrical Engineering and Computer Science Case Western Reserve University Cleveland OH USA Department of Pathology and Tumor biology Kyoto University Kyoto Japan Electrical Engineering and Computer Science Case Western Reserve University Cleveland OH USA Hematology Department University Hospital La Fe Valencia Spain Laboratory of DNA Information Analysis Human Genome Center Institute of Medical Science The University of Tokyo Tokyo Japan Department of Pathology and Tumor Biology Graduate School of Medicine Kyoto University Kyoto Japan Cancer Genomics Project Graduate School of Medicine The University of Tokyo Tokyo Japan Laboratory of Sequence Data Analysis Human Genome Center Institute of Medical Science The University of Tokyo Tokyo Japan Division of Hematology Department of Medicine Showa University School of Medicine Tokyo Japan Department of Hematology and Oncology University Hospital Mannheim Mannheim Germany Division of Hematology Department of Internal Medicine Tokyo Metropolitan Ohtsuka Hospital Tokyo Japan Chang Gung Memorial Hospital Taoyuan Taiwan Department of Hematology Faculty of Medicine University of Tsukuba Tsukuba Japan Translational Hematology Oncology Research Cleveland Clinic Taussig Cancer Institute Cleveland OH USA Department of Translational Hematology and Oncology Research Taussig Cancer Institute Cleveland Clinic Cleveland OH USA Translational Hematology and Oncology Research Taussig Cancer Institute Cleveland Clinic Cleveland OH USA Leukemia Program Department of Hematologic Oncology and Blood Disorders Taussig Cancer Institute Cleveland Clinic Cleveland OH USA

Chromosomal aberrations and somatic mutations constitute key elements of the pathogenesis of myelodysplastic syndromes (MDS), a clonal hematologic malignancy characterized by cytopenias, a dysplastic bone marrow and propensity to clonal evolution. Next generation sequencing (NGS) enables definition of somatic mutational patterns and clonal architecture as a discovery platform, and for clinical *** systematically applied NGS to 707 cases of MDS and MDS-related disorders. 205 cases (low-risk MDS: N=78, high-risk MDS: N=42, MDS/MPN: N=48 and sAML: N=37) were tested by whole exome sequencing (WES). For validation in an additional 502 patients (low-risk MDS: N=192, high-risk MDS: N=104, MDS/MPN: N=111 and sAML: N=95), targeted deep NGS was applied for 60 index genes which were most commonly affected in the cohort analyzed by WES. For NGS data analysis a statistical pipeline was developed to focus on: i) identification of the most relevant somatic mutations, and ii) minimization of false positive results. We studied serial samples from 21 exemplary informative patients. We also compared somatic mutational patterns to those seen in primary AML TCGA cohort (N=201). Given the size of the cohort, there was, for example, a 87% chance of seeing mutations at a frequency of 1% and a 98% of seeing those with a frequency of 2%. While focusing on the most common events, we observed 1117 somatic mutations in 199 genes. The 88 genes mutated mutated in >1% of cases with MDS carried 388 mutations in MDS+sAML (2.5/case), 128 in MDS/MPN (2.7/case) and 398 in pAML (2.0/case). The average number of mutations per case increased during progression (2.2 in lower-risk, 2.8 in higher-risk MDS, 3.4 in sAML). In MDS, the 30 most frequently affected genes were present at least once in 70% of patients. The 30 most frequently mutated genes in MDS/MPN were mutated in 82% of patients. Individual mutations were also sub-grouped according to their function. When we compared three MDS subcateg

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Configurable clutter models for radar simulation

Configurable clutter models for radar simulation

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International Waveform Diversity and Design Conference, WDD 2012

作者： Jezak, Joseph A. Gadola, Guy Berdanier, Charles Levitan, Steven P. Chiarulli, Donald M. Computer Engineering Graduate Program University of Pittsburgh United States Department of Electrical Engineering Wright State University United States Department of Electrical and Computer Engineering University of Pittsburgh United States Department of Computer Science University of Pittsburgh United States

ISBN: (纸本)9781509005987

In this paper we describe an extension to the MATLAB Phased Array Toolkit that adds a configurable clutter object to model clutter signals returned along a specified signal path. The clutter model is based on the Simkins Unified Clutter Model[1]. The current implementation supports sea clutter in any of five sea states with configurable polarization, grazing angle, and beam width. We describe the implementation and give examples of modeled clutter returns. © 2012 IEEE.

关键词： MATLAB

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Forces of Orthodontic Closed Coil Springs Measured using Fiber Bragg Gratings

Forces of Orthodontic Closed Coil Springs Measured using Fib...

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Latin America Optics and Photonics Conference, LAOP 2012

作者： Milczewski, Maura Scandelari Dinisio, Felipe Gonçalves Martelli, Cicero Borges, Paulo César Kalinowski, Hypolito José da Cunha, José Carlos Munhoz Federal University of Technology - Paraná Curitiba80230-901 Brazil Graduate Program on Electrical Engineering and Applied Computer Science Canada Department of Mechanical Engineering Brazilian Dentistry Association Paraná Brazil

The aim of this study is to compare forces generated by three different orthodontic closed coil springs supplied by three companies, optical fiber Bragg gratins are used to evaluate the force of closing of springs. &#... 详细信息

ISBN: (纸本)9781557529589

关键词： Fiber Bragg gratings

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Accelerated DSP functions on the CBE for the X-Midas Toolkit

Accelerated DSP functions on the CBE for the X-Midas Toolkit

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International Waveform Diversity and Design Conference, WDD 2012

作者： Jezak, Joseph A. Berdanier, Charles Levitan, Steven P. Chiarulli, Donald M. Computer Engineering Graduate Program University of Pittsburgh United States USAF AFRL/RYMDA Wright Patterson Air Force Base United States Department of Electrical and Computer Engineering University of Pittsburgh United States Department of Computer Science University of Pittsburgh United States

ISBN: (纸本)9781509005987

We characterize the impact of the Cell Broadband Engine architecture, on commonly used radar DSP algorithms. We use the capabilities of the CBE to accelerate several key computational kernels including Matrix Multiplication, Matrix Inversion, and the Finite Impulse Response (FIR) filter. These algorithms are implemented and benchmarked as library routines within the X-Midas Toolkit. We observe speedups as large as 1200x for complex matrix multiplication, but speedups of 40x to 60x are more typical. We find that system I/O overhead within the X-Midas toolkit severely limited the performance of the applications. © 2012 IEEE.

关键词： FIR filters

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Feasibility study of using social networks platform for learning support: An example of Facebook

Feasibility study of using social networks platform for lear...

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20th International Conference on computers in Education, ICCE 2012

作者： Chan, Chien-Lung Fu, Wen-Erh Lai, K. Robert Tseng, Shu-Fen Department of Information Management Yuan Ze University Taiwan Department of Computer Science and Engineering Yuan Ze University Taiwan Graduate Program in Social Informatics Yuan Ze University Taiwan

ISBN: (纸本)9789810746490

In this study, we explored the students' computer-supported collaborative learning behavior based on the Facebook platform. Sixty two senior college students major in Information Management took Decision Support System (DSS) class. Besides the lectures and class discussion, the students participated in the DSS Facebook for collaborative learning. We found that students' characteristics (e.g., gender and mindset of learning) are important factors to affect their Facebook usage behavior and learning performance. The students using DSS Facebook more often get better performance in their final projects, learning satisfaction and the online communication behavior survey. We also found that gender affects the usage of social networks platform. For instance, male students use social networks platform several times per week and get better performance in online communication, learning satisfaction and creativity self-efficacy.

关键词： Decision support systems

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Finding optimal random boolean networks for reservoir computing

Finding optimal random boolean networks for reservoir comput...

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13th International Conference on the Simulation and Synthesis of Living Systems: Artificial Life 13, ALIFE 2012

作者： Snyder, David Goudarzi, Alireza Teuscher, Christof Department of Computer Science Portland State University Portland OR 97201 United States Systems Science Graduate Program Portland State University Portland OR 97201 United States Department of Electrical and Computer Engineering Portland State University Portland OR 97201 United States

ISBN: (纸本)9780262310505

Reservoir Computing (RC) is a computational model in which a trained readout layer interprets the dynamics of a component called a reservoir that is excited by external input stimuli. The reservoir is often constructed using homogeneous neural networks in which a neuron's in-degree distributions as well as its functions are uniform. RC lends itself to computing with physical and biological systems. However, most such systems are not homogeneous. In this paper, we use Random Boolean Networks (RBN) to build the reservoir. We explore the computational capabilities of such a RC device using the temporal parity task and the temporal density classification. We study the sufficient dynamics of RBNs using kernel quality and generalization rank measures. We verify findings by Lizier et al. (2008) that the critical connectivity of RBNs optimizes the balance between the high memory capacity of RBNs with (K) 2. We show that in a RBN-based RC system, the optimal connectivity for the parity task, a processing intensive task, and the density classification task, a memory intensive task, agree with Lizier et al.'s theoretical results. Our findings may contribute to the development of optimal selfassembled nanoelectronic computer architectures and biologically-inspired computing paradigms. © 2012 Massachusetts Institute of Technology.

关键词： computer architecture

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

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Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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