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7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE

作者： Jesneck, Jonathan L. Mukherjee, Sayan Nolte, Loren W. Lokshin, Anna E. Marks, Jeffrey R. Lo, Joseph Department of Biomedical Engineering Department of Statistical Science Computational Biology and Bioinformatics Program Duke Advanced Imaging Labs. Institute for Genome Sciences and Policy Department of Computer Science Duke University Department of Electrical and Computer Engineering Division of Hematology/Oncology University of Pittsburgh School of Medicine University of Pittsburgh Cancer Institute Pittsburgh PA 15213 United States Department of Experimental Surgery Duke University Medical Center Medical Physics Graduate Program Duke University Durham NC 27708 United States

ISBN: (纸本)1424415098

Current mammographic screeningfor breast cancer is less effective for younger women. To complement mammography for premenopausal women, we investigated the feasibility screening test using 98 blood serum proteins. Because the data set was very noisy and contained only weak features, we used a classifier designed for noisy data: decision fusion. Decision fusion outperformed both a support vector machine (SVM) and linear regression with forward stepwise feature selection on all three two-class classification tasks: normal tissue vs. cancer, normal tissue vs. benign lesions, and benign lesions vs. cancer. Decision fusion detected cancer moderately well (AUC=0.84 on normal vs. cancer), demonstrating promise as a screening tool. Decision fusion also detected benign lesions similarly well (AUC=0.83 on normal vs. benign lesions) and was the only classifier to achieve any success in separating benign from malignant lesions (AUC=0.64 on benign vs. cancer). The classification results suggest that the assayed proteins are more indicative of a secondary effect, such as immune response, rather than specific for breast cancer. In conclusion, the decision fusion classifier demonstrated some promise in detecting breast lesions and outperformed other classifiers, especially for the very noisy classification problem of distinguishing benign from malignant lesions. ©2007 IEEE.

关键词： Tissue

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Real-time recognition of traffic signs using opponent color filters

Real-time recognition of traffic signs using opponent color ...

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14th World Congress on Intelligent Transport Systems, ITS 2007

作者： Baba, Kyoko Hirai, Yuzo Master's Program in Graduate School of Systems and Information Engineering University of Tsukuba 1-1-1 Ten-nodai Tsukuba Ibaraki 305-8573 Japan Department of Computer Science Graduate School of Systems and Information Engineering University of Tsukuba 1-1-1 Ten-nodai Tsukuba Ibaraki 305-8573 Japan

ISBN: (纸本)9781617387777

In order to assist driver's vision, a real-time recognition system for traffic signs is proposed. After detecting sign candidates, biologically inspired opponent-color filters are used to extract symbol parts of signs. After normalizing the size of symbol, structural features are calculated to identify the sign. 5572 segmented images are used to design the algorithm. In a real-time system, the same sign in a sequence of frames is tracked, and a majority vote is used to integrate the recognition results. For test data, 93.8% recall rate and 99.3% precision rate could be attained. In-vehicle experiment also showed high recall and precision rates.

关键词： Traffic signs

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General Type-2 Fuzzy Inference Systems: Analysis, Design and Computational Aspects

General Type-2 Fuzzy Inference Systems: Analysis, Design and...

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IEEE International Conference on Fuzzy Systems (FUZZ-IEEE)

作者： Luis Alberto Lucas Tania Mezzadri Centeno Myriam Regattieri Delgado Graduate School of Electrical Engineering and Applied Computer Science Federal University of Technology of Paraná (UTFPR) Curitiba Pernambuco Brazil

The aim of this work is to handle non-interval type-2 fuzzy logic systems (NIT2 FLS) in a simple manner. We retrieve an alternative representation of Type-2 fuzzy sets (T2 FS) that we call general footprint of uncertainty. Such representation, not only lets us easily visualize T2 FS in two-dimensions but also makes the understanding of basic operations and the inference procedure easier. We introduce the concept of supremum of a T2 FS and translation and cylindric extension for vertical slices to support the adopted inference mechanism, based on the scaled inference mechanism of Type-1 FIS. Finally, we propose a new defuzzification method, the vertical slice centroid type reduction, which requires low computational effort. Some calculations are presented to illustrate that the theory and simplifications proposed in this paper make NIT2 FLS, referred here as general type-2 fuzzy inference systems, much more accessible to FIS designers.

关键词： Fuzzy systems Fuzzy sets Fuzzy logic Uncertainty Inference mechanisms Equations Fuzzy set theory Visualization computer science Plasma welding

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Epley's maneuver in benign paroxysmal positional vertigo associated with Meniere's disease

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Brazilian Journal of Otorhinolaryngology 2007年第4期73卷 506-512页

作者： Ganança, Cristina Freitas Caovilla, Heloisa Helena Gazzola, Juliana Maria Ganança, Maurício Malavasi Ganança, Fernando Freitas Post-Graduate Course on Human Communication Disorders Sao Paulo Federal University - Paulista School of Medicine UNIFESP-EPM Otoneurology Discipline Speech Therapy School UNIFESP-EPM Otoneurology Discipline UNIFSP-EPM UNIFESP-EPM Postgraduate Course on Otorhinolaryngology and Head and Neck Surgery UNIFESP - EPM Department of Otorhinolaryngology UNIFESP-EPM Postgraduate Program for the Master's Degree in the Science of Body Movement Sao Paulo Bandeirante University UNIBAN Vestibular Rehabilitation Unit Otoneurology Discipline UNIFESP - EPM Science of Body Movement Program UNIBAN Sao Paulo Federal University - Paulista School of Medicine (UNIFESP-EPM)

The effects of Epley's maneuver in benign paroxysmal positional vertigo (BPPV) associated with Menière's disease are controversial. Aims: To evaluate the progression of positional vertigo and nystagmus after one or more of Epley's maneuvers in BPPV associated with Menière's disease, and the recurrence of BPPV. Method: a retrospective study of 62 patients with BPPV associated with Menière's disease, that underwent Epley's maneuver, and that were monitored during 12 months after elimination of positional nystagmus. Results: One Epley's maneuver was required to eliminate positional nystagmus in 80.7% of the patients, two in 16.1%, and three in 3.2%;after elimination of nystagmus, positional vertigo was suppressed in 71.0% of the patients, improved in 27.4% and remained unaltered in 1.6%. Four weeks after elimination of positional nystagmus, all patients were asymptomatic. Recurrence of BPPV was seen in 19.4% of the cases, with elimination of the positional vertigo and nystagmus by means of the specific maneuver for the involved canal. Conclusions: In BPPV associated with Menière's disease, vertigo and positioning nystagmus were eliminated with one, two or three Epley maneuvers. BPPV recurrence was resolved by using a specific maneuver for the affected canal. © Revista Brasileira de Otorrinolaringologia. All Rights reserved.

关键词： Dizziness Labyrinth Meniere's disease Positional nystagmus

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Polygon clipping and polygon reconstruction

Polygon clipping and polygon reconstruction

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9th Brazilian Symposium on GeoInformatics, GEOINFO 2007

作者： Azevedo, Leonardo Guerreiro Güting, Ralf Hartmut Computer Science Department Graduate School of Engineering Federal University of Rio de Janeiro PO Box 68511 21945-970 Rio de Janeiro RJ Brazil LG Datenbanksysteme für neue Anwendungen FB Informatik Fernuniversität Hagen D-58084 Hagen Germany

ISBN: (纸本)9788517000362

Polygon clipping is an important operation that computers execute all the time. An algorithm that clips a polygon is rather complex. Each edge of the polygon must be tested against each edge of the clipping window, usually a rectangle. As a result, new edges may be added, and existing edges may be discarded, retained, or divided. Multiple polygons may result from clipping a single polygon. After clipping, we may have a set of segments, which must be handled to generate the clipped polygon. This work proposes two new algorithms: clipping polygon against a rectangle window, and polygon reconstruction from a set of segments. The algorithms were implemented in Secondo, a platform for implementing and experimenting with various kinds of data models.

关键词： Geometry

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Use mathematics and computer to predict Boat's drift for search and rescue

Use mathematics and computer to predict Boat's drift for sea...

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International Multi-Conference on Society, Cybernetics and Informatics, IMSCI 2007

作者： Han, Jim Su, Hui Fang Huang Su, Tsung-Chow Joe Dept. of Computer Engineering and Computer Science Florida Atlantic University Boca Raton FL 33431 United States Graduate Teacher Education Program Nova Southeastern University 1750 NE 167th St. North Miami Beach FL 33162 United States Dept. of Mechanical Engineering Florida Atlantic University Boca Raton FL 33431 United States

ISBN: (纸本)1934272256

Finding a boat in wind and current is an age old problem that puzzled many people throughout history. It is only until recently a simple theory is developed to allow efficient and accurate prediction of the boat's drift trajectory. Such theory could be developed using simple physics and algebra. In this paper, we will describe the derivation of the theory that would give the boat's trajectory in terms of different types of boat condition under given wind field and current field. We will show that the relationship is versatile, and could be used for practical application. We will further implement the results in computer animation setting so that the results can be obtained easily for a given application. The paper demonstrates the power of mathematics and technology to solve problem of boat drift of search and rescue.

关键词： Boats

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Interpreting cabinet approval ratings by neural networks

Interpreting cabinet approval ratings by neural networks

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IASTED International Conference on Artificial Intelligence and Applications, AIA 2007

作者： Kamimura, Ryotaro Yoshida, Fumihiko Kitajima, Ryozo Information Science Laboratory Information Technology Center Tokai University 1117 Kitakaname Hiratsuka Kanagawa 259-1292 Japan Department of Media Studies Tokai University 1117 Kitakaname Hiratsuka Kanagawa 259-1292 Japan Graduate Program in Computer Sciences Tokai University 1117 Kitakaname Hiratsuka Kanagawa 259-1292 Japan

ISBN: (纸本)9780889866317

In this paper, we try to estimate Japan's cabinet approval ratings by using neural networks. In addition, we try to extract the important features in input patterns. This is the first attempt to use neural networks and to interpret the mechanism of inference for approval estimation in a comprehensive way. Experimental results show that neural networks have much better performance than that obtained by the standard regression analysis in terms of training and testing errors. The information loss analysis reveals that the first variable, that is, the previous ratings should play the most important role in inference. Though the experimental result here shown is a preliminary one, it certainly suggests a possibility of the automatic inference of cabinet approval ratings.

关键词： Feature extraction

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Non-Crosshybridizing Oligonucleotide Building Blocks for Accurate, Scalable Nanofabrication

Non-Crosshybridizing Oligonucleotide Building Blocks for Acc...

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IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

作者： Jin-woo Kim Ju Seok Lee Russell Deaton Cell and Molecular Biology Graduate Program University of Arkansas Fayetteville AR USA IEEE Senior Member Cell and Molecular Biology Graduate Program University of Arkansas Fayetteville AR 72701 USA. Department of Computer Science and Computer Engineering University of Arkansas Fayetteville AR 72701 USA.

The urgent need in the field of nanotechnology is functional, reliable, and scalable techniques for more complicated and controlled nanostructures in order to realize nanoscale materials and devices that have practical use and more capability than existing technologies. This paper addresses this need by presenting an in vitro protocol to select large non-crosshybridizing (NCH) libraries of oligonucleotides that provide a large address space of DNA sequences with which to increase both complexity and control in DNA-directed self-assembly processes. The selection protocol was experimentally verified and confirmed. The resultant large NCH libraries would allow self-assembling complex nanostructures with more precise control, leading to reliable, scaled-up, cost-effective manufacturing of nanoscale devices and systems.

关键词： Nanofabrication Nanostructures Nanostructured materials Nanoscale devices Space technology Protocols Libraries Self-assembly Nanotechnology Materials reliability

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Structural characterization of RNA-binding sites of proteins: Preliminary results

Structural characterization of RNA-binding sites of proteins...

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IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

作者： Fadi Towfic David C. Gemperline Cornelia Caragea Feihong Wu Drena Dobbs Vasant Honavar Bioinformatics and Computational Biology Graduate Program Iowa State University Ames IA USA Department of Biology Department of Chemistry Carthage College Kenosha WI USA Department of Computer Science Iowa State University Ames IA USA Department of Genetics Development and Cell Biology Bioinformatics and Computational Biology Graduate Program Iowa State University Ames IA USA Department of Computer Science Bioinformatics and Computational Biology Graduate Program Iowa State University Ames IA USA

We explore whether protein-RNA interfaces differ from non-interfaces in terms of their structural features and whether structural features vary according to the type of the bound RNA (e.g., mRNA, siRNA...etc), using a non-redundant dataset of 147 protein chains extracted from protein-RNA complexes in the protein data bank. Our analysis of surface roughness, solid angle and CX value of amino acid residues for each of the protein chains in the dataset shows that: The protein-RNA interface residues tend to be protruding compared to non-interface residues and tend to have higher surface roughness and exhibit moderately convex or concave solid angles. Furthermore, the protein chains in protein-RNA interfaces that contain Viral RNA and rRNA significantly differ from those that contain dsRNA, mRNA siRNA, snRNA, SRP RNA and tRNA with respect to their CX values. The results of this analysis sug gests the possibility of using such structural features to reliably identify protein-RNA interface residues when the structure of the protein is available but the structures of complexes formed by the protein with RNA are not.

关键词： RNA Protein engineering Biology computing Amino acids Bioinformatics computer interfaces Rough surfaces Surface roughness Solids Machine learning

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Time Based Activity Profiles to Recommend Partnership in a P2P Network

Time Based Activity Profiles to Recommend Partnership in a P...

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International Conference on computer Supported Cooperative Work in Design

作者： Adriana S. Vivacqua Carlos Eduardo R. de Mello Diogo K. de Souza Joao A. de Avellar Menezes Leandro C. Marques Marcos S. Ferreira Jano M. de Souza COPPE/UFRJ Graduate School of Engineering Brazil DCC-IM Dept. of Computer Science Institute of Mathematics Federal University of Rio de Janeiro Brazil

ISBN: (纸本)1424409624

In large communities, finding experts or partners can sometimes be hard. Normally, to find new partners one asks for recommendations from known acquaintances. This is a form of social navigation, whereby one searches for others in the network, who might fit required profiles. Time is an important factor in this type of situation, as needs, interests and expertise levels change rapidly. This paper presents a peer-to-peer system to assist social network navigation and search. It builds user profiles through an analysis of ongoing activities that takes time into account, and matches these to find opportunities for collaboration.

关键词： Collaborative work computer networks Navigation Collaborative tools Design engineering computer science Mathematics Peer to peer computing Social network services Internet

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