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A micromirror array with annular partitioning for high-speed random-access axial focusing

Light(Science & Applications) 2020年第1期9卷 241-255页

作者： Nathan Tessema Ersumo Cem Yalcin Nick Antipa Nicolas Pegard Laura Waller Daniel Lopez Rikky Muller The University of California Berkeley and University of CaliforniaSan Francisco Graduate Program in BioengineeringBerkeleyCA 94720USA Department of Electrical Engineering&Computer Sciences University of CaliforniaBerkeleyCA 94720USA Department of Applied Physical Sciences University of North Carolina at Chapel HillChapel HillNC 27514USA Chan Zuckerberg Biohub San FranciscoCA 94158USA Physical Measurement Laboratory National Institute of Standards and TechnologyGaithersburgMD 20899USA

Dynamic axial focusing functionality has recently experienced widespread incorporation in microscopy,augmented/virtual reality(AR/VR),adaptive optics and material ***,the limitations of existing varifocal tools continue to beset the performance capabilities and operating overhead of the optical systems that mobilize such *** varifocal tools that are the least burdensome to operate(*** crystal,elastomeric or optofluidic lenses)suffer from low(≈100 Hz)refresh ***,the fastest devices sacrifice either critical capabilities such as their dwelling capacity(*** gradient lenses or monolithic micromechanical mirrors)or low operating overhead(*** mirrors).Here,we present a general-purpose random-access axial focusing device that bridges these previously conflicting features of high speed,dwelling capacity and lightweight drive by employing lowrigidity micromirrors that exploit the robustness of defocusing phase ***,the device consists of an 8.2mm diameter array of piston-motion and 48-μm-pitch micromirror pixels that provide 2πphase shifting for wavelengths shorter than 1100 nm with 10-90% settling in 64.8μs(i.e.,15.44 kHz refresh rate).The pixels are electrically partitioned into 32 rings for a driving scheme that enables phase-wrapped operation with circular symmetry and requires<30 V per *** experiments demonstrated the array’s wide focusing range with a measured ability to target 29 distinct resolvable depth ***,the features of the proposed array offer the potential for compact,straightforward methods of tackling bottlenecked applications,including high-throughput single-cell targeting in neurobiology and the delivery of dense 3D visual information in AR/VR.

关键词： mirror axial random

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CONVERGENCE SPEED AND APPROXIMATION ACCURACY OF NUMERICAL MCMC

arXiv

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arXiv 2022年

作者： Cui, Tiangang Dong, Jing Jasra, Ajay Tong, Xin T. School of Mathematics Monash University Australia Graduate School of Business Columbia University United States Applied Mathematics and Computational Science Program Computer Electrical Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Saudi Arabia Department of Mathematics National University of Singapore Singapore

When implementing Markov Chain Monte Carlo (MCMC) algorithms, perturbation caused by numerical errors is sometimes inevitable. This paper studies how perturbation of MCMC affects the convergence speed and Monte Carlo estimation accuracy. Our results show that when the original Markov chain converges to stationarity fast enough and the perturbed transition kernel is a good approximation to the original transition kernel, the corresponding perturbed sampler has similar convergence speed and high approximation accuracy as well. We discuss two different analysis frameworks: ergodicity and spectral gap, both are widely used in the literature. Our results can be easily extended to obtain non-asymptotic error bounds for MCMC estimators. We also demonstrate how to apply our convergence and approximation results to the analysis of specific sampling algorithms, including Random walk Metropolis and Metropolis adjusted Langevin algorithm with perturbed target densities, and parallel tempering Monte Carlo with perturbed densities. Finally we present some simple numerical examples to verify our theoretical claims. Copyright © 2022, The Authors. All rights reserved.

关键词： Inverse problems

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Spatially-varying microscope calibration from unstructured sparse inputs

Spatially-varying microscope calibration from unstructured s...

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Computational Optical Sensing and Imaging, COSI 2020 - Part of Imaging and Applied Optics Congress 2020

作者： Kuo, Grace Monakhova, Kristina Yanny, Kyrollos Ng, Ren Waller, Laura Department of Electrical Engineering and Computer Sciences University of California Berkeley BerkeleyCA94720 United States UCB/UCSF Joint Graduate Program in Bioengineering University of California Berkeley BerkeleyCA94720 United States

We propose a method based on blind deconvolution to calibrate the spatially-varying point spread functions of a coded-aperture microscope system. From easy-to-acquire measurements of unstructured fluorescent beads, we... 详细信息

ISBN: (纸本)9781557528209

关键词： Optical transfer function

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A BCLC Staging System for Hepatocellular Carcinoma using Swin Transformer and CT Imaging

A BCLC Staging System for Hepatocellular Carcinoma using Swi...

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Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

作者： Shun-Cheng Chang Pochuang Wang Weichung Wang Tung-Hung Su Jia-Horng Kao Che Lin Graduate Institute of Communication Engineering National Taiwan University (NTU) Taipei Taiwan Department of Computer Science and Information Engineering NTU Taipei Taiwan NTU Institute of Applied Mathematical Sciences Taipei Taiwan Department of Internal Medicine Division of Gastroenterology and Hepatology National Taiwan University Hospital Taipei Taiwan Department of Electrical Engineering NTU Taipei Taiwan NTU Center for Advanced Computing and Imaging in Biomedicine Taipei Taiwan NTU Smart Medicine and Health Informatics Program Taipei Taiwan

ISBN: (数字)9798350371499

ISBN: (纸本)9798350371505

The Barcelona Clinic Liver Cancer (BCLC) staging system plays a crucial role in clinical planning, offering valuable insights for effectively managing hepatocellular carcinoma. Accurate prediction of BCLC stages can significantly ease the workload on radiologists. However, few datasets are explicitly designed for discerning BCLC stages. Despite the common practice of appending BCLC labels to clinical data within datasets, the inherent imbalance in BCLC distribution is further amplified by the diverse purposes for which datasets are curated. In this study, we aim to develop a BCLC staging system using the advanced Swin Transformer model. Additionally, we explore the integration of two datasets, each originally intended for separate objectives, highlighting the critical challenge of preserving class distribution in practical study designs. This exploration is pivotal for ensuring the applicability of our developed staging system in the designed clinical settings. Our resulting BCLC staging system demonstrates an accuracy of 55.81% (±7.8%), contributing to advancing medical image-based research for predicting BCLC stages.

关键词： Liver cancer Accuracy Computed tomography Biological system modeling Transformers Planning Biomedical imaging

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Exponential Asymptotics using Numerical Rational Approximation in Linear Differential Equations

arXiv

引用

arXiv 2023年

作者： Lustri, Christopher J. Crew, Samuel Jonathan Chapman, S. School of Mathematics and Statistics The University of Sydney NSW2006 Australia Faculty of Computer Science Ruhr Universität Bochum Universitätsstraße Bochum44799 Germany Theoretical Sciences Visiting Program Okinawa Institute of Science and Technology Graduate University Onna904-0495 Japan Mathematical Institute University of Oxford OxfordOX2 6GG United Kingdom

MSC Codes 30E15, 34E15, 34M30, 41A20Singularly-perturbed ordinary differential equations often exhibit Stokes’ phenomenon, which describes the appearance and disappearance of oscillating exponentially small terms across curves in the complex plane known as Stokes curves. These curves originate at singular points in the leading-order solution to the differential equation. In many important problems, it is impossible to obtain a closed-form expression for these leading-order solutions, and it is therefore challenging to locate these singular points. We present evidence that the analytic leading-order solution of a linear differential equation can be replaced with a rational approximation based on a numerical leading-order solution using the adaptive Antoulas-Anderson (AAA) method. We show that the subsequent exponential asymptotic analysis accurately predicts the exponentially small behaviour present in the solution. We explore the limitations of this approach, and show that for sufficiently small values of the asymptotic parameter, this approach breaks down;however, the range of validity may be extended by increasing the number of poles in the rational approximation. We finish by presenting a related nonlinear problem and discussing the challenges that arise when attempting to apply this method to nonlinear problems. © 2023, CC BY.

关键词： Ordinary differential equations

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ReViT: A Hybrid Approach for BCLC Staging of Hepatocellular Carcinoma Using 3D CT with Multiple Instance Learning

ReViT: A Hybrid Approach for BCLC Staging of Hepatocellular ...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Shun-Cheng Chang Hsin-Pei Yu Yi-Hsien Hsieh Pochuang Wang Weichung Wang Tung-Hung Su Jia-Horng Kao Che Lin Graduate Institute of Communication Engineering National Taiwan University (NTU) Taipei Taiwan Department of Computer Science and Information Engineering NTU Taipei Taiwan Institute of Applied Mathematical Sciences NTU Taipei Taiwan Department of Internal Medicine Division of Gastroenterology and Hepatology National Taiwan University Hospital Taipei Taiwan Department of Electrical Engineering NTU Taipei Taiwan Center for Advanced Computing and Imaging in Biomedicine NTU Taipei Taiwan Smart Medicine and Health Informatics Program NTU Taipei Taiwan

ISBN: (数字)9798350351552

ISBN: (纸本)9798350351569

Deep learning has revolutionized medical imaging, offering advanced methods for accurate diagnosis and treatment planning. The BCLC staging system is crucial for staging Hepatocellular Carcinoma (HCC), a high-mortality cancer. An automated BCLC staging system could significantly enhance diagnosis and treatment planning efficiency. However, we found that BCLC staging, which is directly related to the size and number of liver tumors, aligns well with the principles of the Multiple Instance Learning (MIL) framework. To effectively achieve this, we proposed a new preprocessing technique called Masked Cropping and Padding(MCP), which addresses the variability in liver volumes and ensures consistent input sizes. This technique preserves the structural integrity of the liver, facilitating more effective learning. Furthermore, we introduced Re ViT, a novel hybrid model that integrates the local feature extraction capabilities of Convolutional Neural Networks (CNNs) with the global context modeling of Vision Transformers (ViTs). Re ViT leverages the strengths of both architectures within the MIL framework, enabling a robust and accurate approach for BCLC staging. We will further explore the trade-off between performance and interpretability by employing TopK Pooling strategies, as our model focuses on the most informative instances within each bag.

关键词： Visualization Accuracy Three-dimensional displays Liver Transformers Planning Convolutional neural networks Context modeling Biomedical imaging Tumors

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Diffusion-based Reinforcement Learning for Edge-enabled AI-Generated Content Services

TechRxiv

引用

TechRxiv 2023年

作者： Du, Hongyang Li, Zonghang Niyato, Dusit Kang, Jiawen Xiong, Zehui Huang, Huawei Mao, Shiwen School of Computer Science and Engineering The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore School of Information and Communication Engineering University of Electronic Sciences and Technology of China Chengdu China School of Automation Guangdong University of Technology China Pillar of Information Systems Technology and Design Singapore University of Technology and Design Singapore School of Software Engineering Sun Yat-Sen University Zhuhai China Department of Electrical and Computer Engineering Auburn University Auburn United States

As Metaverse emerges as the next-generation Internet paradigm, the ability to efficiently generate content is paramount. AI-Generated Content (AIGC) emerges as a key solution, yet the resource-intensive nature of large Generative AI (GAI) models presents challenges. To address this issue, we introduce an AIGC-as-a-Service (AaaS) architecture, which deploys AIGC models in wireless edge networks to ensure broad AIGC services accessibility for Metaverse users. Nonetheless, an important aspect of providing personalized user experiences requires carefully selecting AIGC Service Providers (ASPs) capable of effectively executing user tasks, which is complicated by environmental uncertainty and variability. Addressing this gap in current research, we introduce the AI-Generated Optimal Decision (AGOD) algorithm, a diffusion model-based approach for generating the optimal ASP selection decisions. Integrating AGOD with Deep Reinforcement Learning (DRL), we develop the Deep Diffusion Soft Actor-Critic (D2SAC) algorithm, enhancing the efficiency and effectiveness of ASP selection. Our comprehensive experiments demonstrate that D2SAC outperforms seven leading DRL algorithms. Furthermore, the proposed AGOD algorithm has the potential for extension to various optimization problems in wireless networks, positioning it as a promising approach for future research on AIGC-driven services. The implementation of our proposed method is available at: https://***/Lizonghang/AGOD. © 2023, CC BY.

关键词： Reinforcement learning

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Nanoslot-Induced Ultrastrong Phonon-Photon and Phonon-Phonon Coupling in Hybrid Organic-Inorganic Perovskites 16

Nanoslot-Induced Ultrastrong Phonon-Photon and Phonon-Phonon...

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16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Kim, Dasom Hou, Jin Lee, Geon Agrawal, Ayush Kim, Sunghwan Zhang, Hao Bao, Di Baydin, Andrey Wu, Wenjing Tay, Fuyang Huang, Shengxi Hagenmüller, Daivd Chia, Elbert E. M. Kim, Dai-Sik Seo, Minah Mohite, Aditya D. Kono, Junichiro Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Department of Materials Science and NanoEngineering Rice University HoustonTX77005 United States Sensor System Research Center Korea Institute of Science and Technology Seoul02792 Korea Republic of Department of Physics and Astronomy Seoul National University Seoul08826 Korea Republic of Department of Chemical and Biomolecular Engineering Rice University HoustonTX77005 United States Ulsan44919 Korea Republic of Division of Physics and Applied Physics School of Physical and Mathematical Sciences Nanyang Technological University 637371 Singapore Smalley-Curl Institute Rice University HoustonTX77005 United States Université de Strasbourg Cnrs Strasbourg67000 France KU-KIST Graduate School of Converging Science and Technology Korea University Seoul02841 Korea Republic of Department of Physics and Astronomy Rice University HoustonTX77005 United States

Methods for harnessing vibrational states are desired for phonon-based technologies. We realized ultrastrong coupling of two phonon modes in perovskite materials induced by ultrastrong coupling with a common photonic ... 详细信息

ISBN: (纸本)9798350372076

关键词： Organic-inorganic materials

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Diffusion-based Reinforcement Learning for Edge-enabled AI-Generated Content Services

arXiv

引用

arXiv 2023年

作者： Du, Hongyang Li, Zonghang Niyato, Dusit Kang, Jiawen Xiong, Zehui Huang, Huawei Mao, Shiwen The School of Computer Science and Engineering The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore The School of Information and Communication Engineering University of Electronic Sciences and Technology of China Chengdu China The School of Automation Guangdong University of Technology China The Pillar of Information Systems Technology and Design Singapore University of Technology and Design Singapore The School of Software Engineering Sun Yat-Sen University Zhuhai China The Department of Electrical and Computer Engineering Auburn University Auburn United States

关键词： Reinforcement learning

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EllipsoNet: Deep-learning-enabled optical ellipsometry for complex thin films

arXiv

引用

arXiv 2022年

作者： Wang, Ziyang Lin, Yuxuan Cosmi Zhang, Kunyan Wu, Wenjing Huang, Shengxi Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Department of Electrical Engineering and Computer Sciences University of California BerkeleyCA94720 United States Department of Electrical Engineering The Pennsylvania State University University ParkPA16802 United States Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States

Optical spectroscopy is indispensable for research and development in nanoscience and nanotechnology, microelectronics, energy, and advanced manufacturing. Advanced optical spectroscopy tools often require both specifically designed high-end instrumentation and intricate data analysis techniques. Beyond the common analytical tools, deep learning methods are well suited for interpreting high-dimensional and complicated spectroscopy data. They offer great opportunities to extract subtle and deep information about optical properties of materials with simpler optical setups, which would otherwise require sophisticated instrumentation. In this work, we propose a computational ellipsometry approach based on a conventional tabletop optical microscope and a deep learning model called EllipsoNet. Without any prior knowledge about the multilayer substrates, EllipsoNet can predict the complex refractive indices of thin films on top of these nontrivial substrates from experimentally measured optical reflectance spectra with high accuracies. This task was not feasible previously with traditional reflectometry or ellipsometry methods. Fundamental physical principles, such as the Kramers-Kronig relations, are spontaneously learned by the model without any further training. This approach enables in-operando optical characterization of functional materials within complex photonic structures or optoelectronic devices. © 2022, CC BY.

关键词： Refractive index

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