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Brazilian Symposium on Computer Graphics and Image Processing (SIBGRAPI)

作者： Luis A. Souza André G. C. Pacheco Gabriel G. de Angelo Thiago Oliveira-Santos Christoph Palm João P. Papa Graduate Program of Informatics Federal University of Espírito Santo Vitória Brazil OTH Regensburg Regensburg Medical Image Computing (ReMIC) Regensburg Germany Department of Computing São Paulo State Univesity São Paulo Brazil

ISBN: (数字)9798350376036

ISBN: (纸本)9798350376043

Skin cancer is the most common type of cancer in the world, accounting for approximately 30% of all diagnosed tumors. Early diagnosis reduces mortality rates and prevents disfiguring effects in different body regions. In recent years, machine learning techniques, particularly deep learning, have shown promising results in this task, presenting studies that have demonstrated that combining a patient's clinical information with images of the lesion is crucial for improving the classification of skin lesions. Despite that, meaningful use of clinical information with multiple images is mandatory, requiring further investigation. Thus, this project aims to contribute to developing multimodal machine learning-based models to cope with the skin lesion classification task employing a lightweight transformer model. As a main hypothesis, models can take multiple images from different sources as input, along with clinical information from the patient's history, leading to a more reliable diagnosis. Our model deals with the not-trivial task of combining images and clinical information (from anamneses) concerning the skin lesions in a lightweight transformer architecture that does not demand high computation resources but still presents competitive classification results.

关键词： Graphics Computational modeling Computer architecture Transformers Skin Lesions Clinical diagnosis Reliability History Skin cancer

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Predicting Microsatellite Instability from Histology Images with Dilated Neighborhood Attention Transformer in Colorectal Cancer 24

Predicting Microsatellite Instability from Histology Images ...

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24th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2024

作者： Chen, Yun-Chi Chao, Tung Phandita, Wimaya Nitya Sun, Tzu-Yu Wang, Huai-Zhi Hsieh, Yi-Hsien Hsu, Le-Yin Lin, Che Taipei Taiwan College of Bioresources and Agriculture NTU Taipei Taiwan National Taiwan University of Science and Technology Department of Computer Science and Information Engineering Taipei Taiwan Graduate Institute of Communication Engineering NTU Taipei Taiwan NTU Data Science Degree Program Taipei Taiwan NTU Department of Electrical Engineering Taipei Taiwan Center for Advanced Computing and Imaging in Biomedicine NTU Taipei Taiwan NTU Smart Medicine and Health Informatics Program Taipei Taiwan

ISBN: (纸本)9798331518622

Microsatellite instability (MSI) is a pivotal genetic marker influencing the efficacy of immunotherapy in colorectal cancer. Traditional MSI examination often requires additional genetic or immunohistochemical tests, whereas histology images, widely available in colorectal cancer diagnosis, offer a valuable alternative for MSI prediction. Although Transformer-based models have demonstrated promising outcomes in predicting MSI from histology images, they are hampered by traditional local attention mechanisms that struggle to capture long-range interdependencies and establish a comprehensive global receptive field. In this study, we introduce DiNAT-MSI, a novel framework for histology-based MSI prediction that incorporates the Dilated Neighborhood Attention Transformer (DiNAT). This model enhances global context recognition and substantially expands receptive fields, all without additional computational burden. Our results demonstrate that DiNAT-MSI achieves a superior patientwise AUROC compared to ResNet18 and Swin Transformer, along with commendable explainability. Our work not only illustrates a more accessible diagnostic tool for leveraging histological data but also underscores the potential of Transformerbased models with sophisticated attention designs in advancing precision medicine for colorectal cancer patients. © 2024 IEEE.

关键词： Diseases

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Improving Students Skills to Solve Elementary Equations in K-12 programs Using an Intelligent Tutoring System

Improving Students Skills to Solve Elementary Equations in K...

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Frontiers in Education (FIE) Conference

作者： Arcanjo Miguel Mota Lopes José Francisco de Magalhães Netto Ricardo A. L. de Souza Andreza Bastos Mourão Thais Oliveira Almeida Dhanielly P. R. de Lima Post-Graduate Program in Informatics (PPGI) Institute of Computing (IComp) Federal University of Amazonas (UFAM) Manaus AM Brazil Institute of Exact Sciences (ICE) Federal University of Amazonas (UFAM) Manaus AM Brazil University of State of Amazonas (UEA) Post-Graduate Program in Informatics (PPGI) Institute of Computing (IComp) Federal University of Amazonas (UFAM) Manaus AM Brazil Department of Science Computer Federal University of Roraima Boa Vista RR Brazil

ISBN: (数字)9781728117461

ISBN: (纸本)9781728117478

This full paper of research to practice category describes an experiment using an Intelligent Tutoring System to support teaching and learning that evolve solutions of first-degree equations. The difficulties encountered in solving algebra problems can make students consider math and related science a difficult task. We propose a Tutor to promote the learning of this class of problems. In this article, we describe the functioning and architecture of the tutor composed by the Interface, Student Model, Tutorial Strategies and Domain Model. Also, a Virtual Assistant was included to motivate students in the learning process. The tutoring strategies that comprise the tutor are projected from models found in the literature. To approximate the interactions of the tutor with the actions of the teachers, Lev Vygotsky's Concept of Zone Proximal Development was used. The methodology used in this project was the case study applied in a real-life context, obtaining a combination of quantitative and qualitative evidence about technical and pedagogical usability that show the degree of satisfaction of the students regarding the proposed approach.

关键词： Education Mathematical model informatics Abstract algebra Cognition

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Collaborative information gathering and recommendation using mobile computing

Collaborative information gathering and recommendation using...

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International Conference on Computer Supported Cooperative Work in Design

作者： Jonice Oliveira Andressa Silva Raphael Franckini Graduate Program in Informatics (PPGI) Department of Computing Science (DCC) Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Department of Computing Science (DCC) Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

ISBN: (纸本)9781467360845

The increasing adoption of mobile devices can improve the collaborative participation, especially in data acquiring, of people in their space: where they live or where they work. Based in this kind of crowdsourcing, we create a proposal for The Federal University of Rio de Janeiro (UFRJ), specially its campus of “Ilha do Fundão” (Fundão Island), which has a fragmented culture since its origin. Nowadays, it is still possible to find not only a geographical distance, but also informational disaggregation and waste of resources and opportunities. In order to minimize these problems, as well motivating the collaborative work, we create an approach using mobile computing, called UFRJ Social. The main idea is that the crowd (students, professor, employers, visitors and anyone who stay in the campus) can provide information or opinions of any place (infrastructure, events, classes, bus stations and others). This application is context-sensitive, and users can receive recommendations by their geographical location and interests. This approach was evaluated in a study case and the results were positive. In this paper we also analyze how this approach can be extended in other scenarios.

关键词： Educational institutions Collaboration Mobile handsets Internet Context Proposals Communities

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Multi-task Learning Graph Neural Networks for Cancer Prognosis Prediction with Genomic Data

Multi-task Learning Graph Neural Networks for Cancer Prognos...

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Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

作者： Tsung-Wei Lin Sofia Ormazabal Arriagada Che Lin Graduate Institute of Communication Engineering National Taiwan University (NTU) Taiwan International Graduate Program AIoT NTU Research Center for Information Technology Innovation Academia Sinica Department of Electrical Engineering NTU Center for Advanced Computing and Imaging in Biomedicine NTU Smart Medicine and Health Informatics Program NTU

ISBN: (数字)9798350371499

ISBN: (纸本)9798350371505

Providing robust prognosis predictions for cancers with limited data samples remains a challenge for precision oncology. In this study, we propose a novel approach that combines multi-task learning (MTL) and graph neural networks (GNNs) to address this issue. By representing gene-gene interactions as a graph network, our approach leverages multi-task learning to effectively capture the relationships of genes relevant to the oncogenesis and progression of breast, lung, and colon cancer. We demonstrate that our approach improves the cancer prognosis prediction for cancers with fewer samples, such as colon adenocarcinoma, by leveraging the shared gene-gene interactions across different cancer types, obtaining increases in the area under the precision-recall curve (AUPRC) of 24%. Our work contributes to the field of smart healthcare by demonstrating the potential of MTL and GNNs for enhancing cancer prognosis prediction, even with limited data samples.

关键词： Lungs Genomics Medical services Colorectal cancer Breast Multitasking Oncology Graph neural networks Prognostics and health management Cancer

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Multiversion Low-Power Hardware Accelerator for the AV1 Interpolation Filters

Multiversion Low-Power Hardware Accelerator for the AV1 Inte...

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IEEE International Symposium on Circuits and Systems (ISCAS)

作者： Daiane Freitas Mateus Grellert Cláudio M. Diniz Guilherme Correa Video Technology Research Group (ViTech) Graduate Program in Computing (PPGC) Federal University of Pelotas (UFPel) Embedded Computing Lab (ECL) Federal University of Santa Catarina (UFSC) PGMICRO Institute of Informatics (INF) Federal University of Rio Grande do Sul (UFRGS)

One of the new tools included in the AV1 video codec is the adaptive filtering scheme used in the sample interpolation process. This scheme includes three different filter families called Regular, Sharp and Smooth, offering high flexibility for motion estimation (ME) and motion compensation (MC). However, the high number of interpolation filters also leads to greater complexity and energy consumption, since the generation of samples at sub-pixel position is a costly process. This paper proposes a low-power and high-throughput hardware accelerator focused on the AV1 interpolation filters called Multiversion Interpolation Processor (MVIP). The accelerator includes the three AV1 interpolation filter families, with versions that employ operand isolation for power reduction in unused filters. The accelerator also includes a precise MVIP assuming the MC scenario, besides two approximate versions to reduce the cost on the ME scenario. The proposed design is able to process 8K video at 50fps in MC and 2,656.14 Msamples/sec in ME, with a power dissipation of 41.30mW.

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VLSI Design of Tree-Based Inference for Low-Power Learning Applications

VLSI Design of Tree-Based Inference for Low-Power Learning A...

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IEEE International Symposium on Circuits and Systems (ISCAS)

作者： Brunno A. Abreu Mateus Grellert Sergio Bampi Graduate Program in Microelectronics (PGMICRO) INF-UFRGS Federal University of Rio Grande do Sul Porto Alegre Brazil Department of Informatics and Statistics − INE Federal University of Santa Catarina (UFSC) Florianópolis Brazil Graduate Program on Electronic Engineering and Computing Catholic University of Pelotas (UCPel) Pelotas Brazil

ISBN: (数字)9781728133201

ISBN: (纸本)9781728133218

The use of Machine Learning techniques in battery-powered devices has increased in recent years. Therefore, evaluating power-accuracy trade-offs of inference models has become important. This work explores decision trees architectures, analyzing the effects of model complexity and approximation in power and accuracy. By quantizing the inputs to limited widths, we increased the accuracy of the models in up to 8.7% compared to precise cases. In terms of power, the variation in model complexity was more significant than in input width, as we obtained reductions of up to 97% by decreasing the tree depth, compared to 88% when decreasing the width.

关键词： Complexity theory Hardware Integrated circuit modeling Training Analytical models Decision trees Quantization (signal)

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Goal-oriented inference of environment from redundant observations

arXiv

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arXiv 2023年

作者： Takahashi, Kazuki Fukai, Tomoki Sakai, Yutaka Takekawa, Takashi Informatics Program Graduate School of Engineering Kogakuin University of Technology and Engineering Japan Neural Coding and Brain Computing Unit Okinawa Institute of Science and Technology Japan Brain Science Institute Tamagawa University Japan

The agent learns to organize decision behavior to achieve a behavioral goal, such as reward maximization, and reinforcement learning is often used for this optimization. Learning an optimal behavioral strategy is difficult under the uncertainty that events necessary for learning are only partially observable, called as Partially Observable Markov Decision Process (POMDP). However, the real-world environment also gives many events irrelevant to reward delivery and an optimal behavioral strategy. The conventional methods in POMDP, which attempt to infer transition rules among the entire observations, including irrelevant states, are ineffective in such an environment. Supposing Redundantly Observable Markov Decision Process (ROMDP), here we propose a method for goal-oriented reinforcement learning to efficiently learn state transition rules among reward-related"core states" from redundant observations. Starting with a small number of initial core states, our model gradually adds new core states to the transition diagram until it achieves an optimal behavioral strategy consistent with the Bellman equation. We demonstrate that the resultant inference model outperforms the conventional method for POMDP. We emphasize that our model only containing the core states has high explainability. Furthermore, the proposed method suits online learning as it suppresses memory consumption and improves learning speed. Copyright © 2023, The Authors. All rights reserved.

关键词： Reinforcement learning

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Machine Learning for Prediction of Adverse Drug Reactions: Application to Neonatal Intensive Care Units

SSRN

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SSRN 2023年

作者： do Nascimento, Amanda Roseane Farias Greati, Victor Rodrigues Leopoldino, Ramon Weyler Duarte Martins, Rand Randall Barbosa, Euzebio Guimarães Graduate Program in Pharmaceutical Sciences Health Sciences Center Federal University of Rio Grande do Norte Rio Grande do Norte Natal Brazil Graduate Program in Systems and Computing Department of Informatics and Applied Mathematics Federal University of Rio Grande do Norte Rio Grande do Norte Natal Brazil

Introduction: The intensive care of neonates is associated with the entry of a large volume of data in their medical records. The treatment of this data can be done through Machine Learning: a tool capable of assisting in the detection and decision-making of a wide range of medical conditions, including adverse drug reactions (ADR). Objective: To train a prediction model to assist in the detection of adverse drug reactions in neonates admitted to an ICU. Methodology: observational study developed in the Neonatal Intensive Care Unit of a teaching hospital in Brazil. Clinical data were collected from daily pharmacotherapeutic follow-up, processed and analyzed by machine learning through libraries written in Python language. Results: Eight hundred and three neonates were included in the study, with a mean gestational age of 32.2 ± 4.2 weeks and mean birth weight of 1807.2 ± 936.6g. The incidence of ADR was 10.8%. Antimicrobials, especially aminoglycosides, were the most prescribed drugs for this population. An algorithm was trained and tested to predict ADR in the NICU, in which the metrics were precision (0.35) and recall (0.823), with specificity (80%) and sensitivity (67%). Conclusion: There is a high potential in the machine learning method to predict ADR in neonates admitted to an ICU. © 2023, The Authors. All rights reserved.

关键词： Forecasting

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Stroke Lesion Detection Using Convolutional Neural Networks

Stroke Lesion Detection Using Convolutional Neural Networks

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International Joint Conference on Neural Networks

作者： Danillo Roberto Pereira Pedro P. Reboucas Filho Gustavo Henrique de Rosa Joao Paulo Papa Victor Hugo C. de Albuquerque Department of Computing São Paulo State University Bauru SP Brazil Federal Institute of Education Science and Technology of Ceará CE Brazil Graduate Program in Applied Informatics University of Fortaleza Fortaleza CE Brazil

Stroke is an injury that affects the brain tissue, mainly caused by changes in the blood supply to a particular region of the brain. As consequence, some specific functions related to that affected region can be reduced, decreasing the quality of life of the patient. In this work, we deal with the problem of stroke detection in Computed Tomography (CT) images using Convolutional Neural Networks (CNN) optimized by Particle Swarm Optimization (PSO). We considered two different kinds of strokes, ischemic and hemorrhagic, as well as making available a public dataset to foster the research related to stroke detection in the human brain. The dataset comprises three different types of images for each case, i.e., the original CT image, one with the segmented cranium and an additional one with the radiological density's map. The results evidenced that CNN's are suitable to deal with stroke detection, obtaining promising results.

关键词： Computed tomography Hemorrhaging Brain Attenuation Blood Image segmentation Cranium

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