检索结果-内蒙古大学图书馆

arXiv 2020年

作者： Petropoulos, Fotios Apiletti, Daniele Assimakopoulos, Vassilios Babai, Mohamed Zied Barrow, Devon K. Taieb, Souhaib Ben Bergmeir, Christoph Bessa, Ricardo J. Bijak, Jakub Boylan, John E. Browell, Jethro Carnevale, Claudio Castle, Jennifer L. Cirillo, Pasquale Clements, Michael P. Cordeiro, Clara Oliveira, Fernando Luiz Cyrino de Baets, Shari Dokumentov, Alexander Ellison, Joanne Fiszeder, Piotr Franses, Philip Hans Frazier, David T. Gilliland, Michael Gönül, M. Sinan Goodwin, Paul Grossi, Luigi Grushka-Cockayne, Yael Guidolin, Mariangela Guidolin, Massimo Gunter, Ulrich Guo, Xiaojia Guseo, Renato Harvey, Nigel Hendry, David F. Hollyman, Ross Januschowski, Tim Jeon, Jooyoung Jose, Victor Richmond R. Kang, Yanfei Koehler, Anne B. Kolassa, Stephan Kourentzes, Nikolaos Leva, Sonia Li, Feng Litsiou, Konstantia Makridakis, Spyros Martin, Gael M. Martinez, Andrew B. Meeran, Sheik Modis, Theodore Nikolopoulos, Konstantinos Önkal, Dilek Paccagnini, Alessia Panagiotelis, Anastasios Panapakidis, Ioannis Pavía, Jose M. Pedio, Manuela Pedregal, Diego J. Pinson, Pierre Ramos, Patrícia Rapach, David E. Reade, J. James Rostami-Tabar, Bahman Rubaszek, Michal Sermpinis, Georgios Shang, Han Lin Spiliotis, Evangelos Syntetos, Aris A. Talagala, Priyanga Dilini Talagala, Thiyanga S. Tashman, Len Thomakos, Dimitrios Thorarinsdottir, Thordis Todini, Ezio Arenas, Juan Ramón Trapero Wang, Xiaoqian Winkler, Robert L. Yusupova, Alisa Ziel, Florian School of Management University of Bath United Kingdom Politecnico di Torino Turin Italy Forecasting and Strategy Unit School of Electrical and Computer Engineering National Technical University of Athens Greece Kedge Business School France Department of Management Birmingham Business School University of Birmingham United Kingdom Belgium Faculty of Information Technology Monash University Melbourne Australia INESC TEC – Institute for Systems and Computer Engineering Technology and Science Porto Portugal Department of Social Statistics and Demography University of Southampton United Kingdom Centre for Marketing Analytics and Forecasting Lancaster University Management School Lancaster University United Kingdom School of Mathematics and Statistics University of Glasgow United Kingdom Department of Mechanical and Industrial Engineering University of Brescia Italy Magdalen College University of Oxford United Kingdom ZHAW School of Management and Law Zurich University of Applied Sciences Switzerland ICMA Centre Henley Business School University of Reading United Kingdom Faculdade de Ciências e Tecnologia Universidade do Algarve Portugal CEAUL Faculdade de Ciências Universidade de Lisboa Portugal Brazil Department of Business Informatics and Operations Management Faculty of Economics and Business Administration Universiteit Gent Belgium Let’s Forecast Australia Faculty of Economic Sciences and Management Nicolaus Copernicus University in Torun Poland Econometric Institute Erasmus School of Economics Rotterdam Netherlands Department of Econometrics and Business Statistics Monash University Melbourne Australia SAS United States Newcastle Business School Northumbria University Newcastle upon Tyne United Kingdom Department of Statistical Sciences University of Padua Italy Darden School of Business University of Virginia United States Finance Department Bocconi University Baffi-CAREFIN Centre Milan Italy Department of Tourism and Service Management MODUL Un

Forecasting has always been at the forefront of decision making and planning. The uncertainty that surrounds the future is both exciting and challenging, with individuals and organisations seeking to minimise risks and maximise utilities. The large number of forecasting applications calls for a diverse set of forecasting methods to tackle real-life challenges. This article provides a non-systematic review of the theory and the practice of forecasting. We provide an overview of a wide range of theoretical, state-of-the-art models, methods, principles, and approaches to prepare, produce, organise, and evaluate forecasts. We then demonstrate how such theoretical concepts are applied in a variety of real-life contexts. We do not claim that this review is an exhaustive list of methods and applications. However, we wish that our encyclopedic presentation will offer a point of reference for the rich work that has been undertaken over the last decades, with some key insights for the future of forecasting theory and practice. Given its encyclopedic nature, the intended mode of reading is non-linear. We offer cross-references to allow the readers to navigate through the various topics. We complement the theoretical concepts and applications covered by large lists of free or open-source software implementations and publicly-available databases. © 2020, CC BY.

关键词： Forecasting

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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Short-Term Effects of a Therapeutic Diet on Biochemical Parameters in Hemodialysis Patients: A Randomized Crossover Trial

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Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2023年第6期33卷 731-739页

作者： Wan-Chuan Tsai Shih-Ping Hsu Yen-Ling Chiu Hon-Yen Wu Chia-Chin Luan Ju-Yeh Yang Mei-Fen Pai Cheng-Jui Lin Wan-Yu Lin Wen-Huei Sun Yu-Sen Peng Division of Nephrology Department of Internal Medicine Far Eastern Memorial Hospital New Taipei City Taiwan Center for General Education Lee-Ming Institute of Technology New Taipei City Taiwan. School of Life Science National Taiwan Normal University Taipei City Taiwan. Graduate Program in Biomedical Informatics Yuan Ze University Taoyuan City Taiwan. Institute of Epidemiology and Preventive Medicine College of Public Health National Taiwan University Taipei City Taiwan Faculty of Medicine School of Medicine National Yang-Ming University Taipei City Taiwan. Dietary Department Far Eastern Memorial Hospital New Taipei City Taiwan. Division of Nephrology Department of Internal Medicine Far Eastern Memorial Hospital New Taipei City Taiwan. Division of Nephrology Department of Internal Medicine Mackay Memorial Hospital Taipei City Taiwan Department of Medicine Mackay Medical College Taipei City Taiwan Mackay Junior College of Medicine Nursing and Management Taipei City Taiwan. Institute of Epidemiology and Preventive Medicine College of Public Health National Taiwan University Taipei City Taiwan. Dietary Department Far Eastern Memorial Hospital New Taipei City Taiwan. Electronic address: 830636231@mail.femh.org.tw. Department of Applied Cosmetology Lee-Ming Institute of Technology New Taipei City Taiwan Department of Electrical Engineering Yuan Ze University Taoyuan City Taiwan. Electronic address: taan70@***.

OBJECTIVE:Although unhealthy diets exacerbate nutritional and metabolic derangements in patients with end-stage kidney disease (ESKD), how therapeutic diets that possess a variety of different dietary strategies acutely modify diverse biochemical parameters related to cardiovascular disease remains underexplored. METHODS:Thirty-three adults with end-stage kidney disease undergoing thrice-weekly hemodialysis participated in a randomized crossover trial comparing a therapeutic diet with their usual diets for 7 days, separated by a 4-week washout period. The therapeutic diet was characterized by adequate calorie and protein amounts, natural food ingredients with a low phosphorus-to-protein ratio, higher portions of plant-based food, and high fiber content. The primary outcome measure was the mean difference in the change-from-baseline intact fibroblast growth factor 23 (FGF23) level between the 2 diets. The other outcomes of interest included changes in mineral parameters, uremic toxins, and high-sensitivity C-reactive protein (hs-CRP) levels. RESULTS:Compared with the usual diet, the therapeutic diet lowered intact FGF23 levels (P = .001), decreased serum phosphate levels (P < .001), reduced intact parathyroid hormone (PTH) levels (P = .003), lowered C-terminal FGF23 levels (P = .03), increased serum calcium levels (P = .01), and tended to lower total indoxyl sulfate levels (P = .07) but had no significant effect on hs-CRP levels. Among these changes, reduction in serum phosphate level achieved in 2 days, modifications of intact PTH and calcium levels in 5 days, and reductions in intact and C-terminal FGF23 levels in 7 days of therapeutic diet intervention. CONCLUSION:Within the 1-week intervention period, the dialysis-specific therapeutic diet rapidly reversed mineral abnormalities and tended to decrease total indoxyl sulfate levels in patients undergoing hemodialysis but had no effect on inflammation. Future studies to assess the long-term effects of such therapeuti

关键词： FGF23 dialysis inflammation therapeutic diet uremic toxin

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The ACROBAT 2022 Challenge: Automatic Registration Of Breast Cancer Tissue

arXiv

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arXiv 2023年

作者： Weitz, Philippe Valkonen, Masi Solorzano, Leslie Carr, Circe Kartasalo, Kimmo Boissin, Constance Koivukoski, Sonja Kuusela, Aino Rasic, Dusan Feng, Yanbo Pouplier, Sandra Sinius Sharma, Abhinav Eriksson, Kajsa Ledesma Robertson, Stephanie Marzahl, Christian Gatenbee, Chandler D. Anderson, Alexander R.A. Wodzinski, Marek Jurgas, Artur Marini, Niccolò Atzori, Manfredo Müller, Henning Budelmann, Daniel Weiss, Nick Heldmann, Stefan Lotz, Johannes Wolterink, Jelmer M. De Santi, Bruno Patil, Abhijeet Sethi, Amit Kondo, Satoshi Kasai, Satoshi Hirasawa, Kousuke Farrokh, Mahtab Kumar, Neeraj Greiner, Russell Latonen, Leena Laenkholm, Anne-Vibeke Hartman, Johan Ruusuvuori, Pekka Rantalainen, Mattias Department of Medical Epidemiology and Biostatistics Karolinska Insitutet Stockholm Sweden Institute of Biomedicine University of Turku Turku Finland Institute of Biomedicine University of Eastern Finland Kuopio Finland Department of Surgical Pathology Zealand University Hospital Roskilde Denmark Department of Oncology and Pathology Karolinska Institutet Stockholm Sweden Gestalt Diagnostics Spokane United States Department of Integrated Mathematical Oncology Moffitt Cancer Center Tampa United States Informatics Institute University of Applied Sciences Western Switzerland Switzerland Department of Measurement and Electronics Agh University of Kraków Poland Department of Computer Science University of Geneva Geneva Switzerland Department of Neuroscience University of Padova Italy Medical Faculty University of Geneva Switzerland Fraunhofer Institute for Digital Medicine Mevis Lübeck Germany Department of Applied Mathematics Technical Medical Centre University of Twente Enschede Netherlands Multimodality Medical Imaging Technical Medical Centre University of Twente Enschede Netherlands Department of Electrical Engineering Indian Institute of Technology Bombay India Graduate School of Engineering Muroran Institute of Technology Hokkaido Japan Faculty of Medical Technology Niigata University of Health and Welfare Niigata Japan Forxai Business Operations Konica Minolta Inc. Osaka Japan Department of Computing Science University of Alberta EdmontonAB Canada Alberta Machine Intelligence Institute Edmonton Canada MedTechLabs BioClinicum Karolinska University Hospital Stockholm Sweden Faculty of Medicine and Health Technology Tampere University Tampere Finland

The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for research and clinical applications. Advances in computing, deep learning, and availability of large WSI datasets have revolutionised WSI analysis. Therefore, the current state-of-the-art in WSI registration is unclear. To address this, we conducted the ACROBAT challenge, based on the largest WSI registration dataset to date, including 4,212 WSIs from 1,152 breast cancer patients. The challenge objective was to align WSIs of tissue that was stained with routine diagnostic immunohistochemistry to its H&E-stained counterpart. We compare the performance of eight WSI registration algorithms, including an investigation of the impact of different WSI properties and clinical covariates. We find that conceptually distinct WSI registration methods can lead to highly accurate registration performances and identify covariates that impact performances across methods. These results establish the current state-of-the-art in WSI registration and guide researchers in selecting and developing methods. Copyright © 2023, The Authors. All rights reserved.

关键词： Tissue

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The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue

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Medical Image Analysis 2024年 97卷 103257页

作者： Weitz, Philippe Valkonen, Masi Solorzano, Leslie Carr, Circe Kartasalo, Kimmo Boissin, Constance Koivukoski, Sonja Kuusela, Aino Rasic, Dusan Feng, Yanbo Pouplier, Sandra Sinius Sharma, Abhinav Eriksson, Kajsa Ledesma Robertson, Stephanie Marzahl, Christian Gatenbee, Chandler D. Anderson, Alexander R.A. Wodzinski, Marek Jurgas, Artur Marini, Niccolò Atzori, Manfredo Müller, Henning Budelmann, Daniel Weiss, Nick Heldmann, Stefan Lotz, Johannes Wolterink, Jelmer M. De Santi, Bruno Patil, Abhijeet Sethi, Amit Kondo, Satoshi Kasai, Satoshi Hirasawa, Kousuke Farrokh, Mahtab Kumar, Neeraj Greiner, Russell Latonen, Leena Laenkholm, Anne-Vibeke Hartman, Johan Ruusuvuori, Pekka Rantalainen, Mattias Department of Medical Epidemiology and Biostatistics Karolinska Insitutet Stockholm Sweden Institute of Biomedicine University of Turku Turku Finland Institute of Biomedicine University of Eastern Finland Kuopio Finland Department of Surgical Pathology Zealand University Hospital Roskilde Denmark Department of Oncology and Pathology Karolinska Institutet Stockholm Sweden Gestalt Diagnostics Spokane United States Department of Integrated Mathematical Oncology Moffitt Cancer Center Tampa United States Informatics Institute University of Applied Sciences Western Switzerland Switzerland Department of Measurement and Electronics AGH University of Kraków Poland Department of Computer Science University of Geneva Geneva Switzerland Department of Neuroscience University of Padova Italy Medical Faculty University of Geneva Switzerland Fraunhofer Institute for Digital Medicine MEVIS Lübeck Germany Department of Applied Mathematics Technical Medical Centre University of Twente Enschede Netherlands Multimodality Medical Imaging Technical Medical Centre University of Twente Enschede Netherlands Department of Electrical Engineering Indian Institute of Technology Bombay India Graduate School of Engineering Muroran Institute of Technology Hokkaido Japan Faculty of Medical Technology Niigata University of Health and Welfare Niigata Japan FORXAI Business Operations Konica Minolta Inc. Osaka Japan Department of Computing Science University of Alberta EdmontonAlberta United States Alberta Machine Intelligence Institute Edmonton Canada MedTechLabs BioClinicum Karolinska University Hospital Stockholm Sweden Faculty of Medicine and Health Technology Tampere University Tampere Finland

The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for research and clinical applications. Advances in computing, deep learning, and availability of large WSI datasets have revolutionised WSI analysis. Therefore, the current state-of-the-art in WSI registration is unclear. To address this, we conducted the ACROBAT challenge, based on the largest WSI registration dataset to date, including 4,212 WSIs from 1,152 breast cancer patients. The challenge objective was to align WSIs of tissue that was stained with routine diagnostic immunohistochemistry to its H&E-stained counterpart. We compare the performance of eight WSI registration algorithms, including an investigation of the impact of different WSI properties and clinical covariates. We find that conceptually distinct WSI registration methods can lead to highly accurate registration performances and identify covariates that impact performances across methods. These results provide a comparison of the performance of current WSI registration methods and guide researchers in selecting and developing methods. © 2024

关键词： Tissue

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Mapping the Human Body at Cellular Resolution -- The NIH Common Fund Human BioMolecular Atlas program

arXiv

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arXiv 2019年

作者： Snyder, Michael P. Lin, Shin Posgai, Amanda Atkinson, Mark Regev, Aviv Rood, Jennifer Rozenblatt-Rosen, Orit Gaffney, Leslie Hupalowska, Anna Satija, Rahul Gehlenborg, Nils Shendure, Jay Laskin, Julia Harbury, Pehr Nystrom, Nicholas A. Bar-Joseph, Ziv Zhang, Kun Börner, Katy Lin, Yiing Conroy, Richard Procaccini, Dena Roy, Ananda L. Pillai, Ajay Brown, Marishka Galis, Zorina S. Cai, Long Shendure, Jay Trapnell, Cole Lin, Shin Jackson, Dana Snyder, Michael P. Nolan, Garry Greenleaf, William James Lin, Yiing Plevritis, Sylvia Ahadi, Sara Lee, Hayan Nevins, Stephanie Esplin, Ed Horning, Aaron Bahmani, Amir Zhang, Kun Sun, Xin Jain, Sanjay Hagood, James Kharchenko, Peter Atkinson, Mark Bodenmiller, Bernd Brusko, Todd Clare-Salzler, Michael Nick, Harry Otto, Kevin Posgai, Amanda Wasserfall, Clive Maffioletti, Sergio Caprioli, Richard M. Spraggins, Jeffrey M. Gutierrez, Danielle Patterson, Nathan Heath Neumann, Elizabeth K. Harris, Raymond deCaestecker, Mark de Plas, Raf Van Lau, Ken Cai, Long Yuan, Guo-Cheng Zhu, Qian Dries, Ruben Yin, Peng Saka, Sinem K. Kishi, Jocelyn Y. Wang, Yu Goldaracena, Isabel Laskin, Julia Ye, DongHye Burnum-Johnson, Kristin E. Piehowski, Paul D. Ansong, Charles Zhu, Ying Harbury, Pehr Desai, Tushar Mulye, Jay Chou, Peter Nagendran, Monica Bar-Joseph, Ziv Teichmann, Sarah A. Paten, Benedict Murphy, Robert F. Ma, Jian Kiselev, Vladimir Yu Kingsford, Carl Ricarte, Allyson Ruffalo, Matthew Gehlenborg, Nils Kharchenko, Peter Vella, Margaret McCallum, Chuck Börner, Katy Cross, Leonard E. Friedman, Samuel H. Heiland, Randy Herr, Bruce Macklin, Paul Quardokus, Ellen M. Record, Lisel Sluka, James P. Weber, Griffin M. Nystrom, Nicholas A. Silverstein, Jonathan C. Blood, Philip D. Ropelewski, Alexander J. Shirey, William E. Mabee, Paula Lenhardt, W. Christopher Robasky, Kimberly Michailidis, Stavros Satija, Rahul Marioni, John Regev, Aviv Butler, Andrew Stuart, Tim Fisher, Eyal Ghazanfar, Shila Rood, Jennifer Gaffney, Leslie Ersalan, Gokcen Biancalani, Tommaso Conroy, Richard Procaccini, Dena Roy, Anan School of Medicine Stanford University 300 Pasteur Drive United States Department of Genetics Stanford School of Medicine StanfordCA94305 United States Department of Medicine University of Washington SeattleWA98195 United States Department of Pathology University of Florida Diabetes Institute GainesvilleFL32610 United States Klarman Cell Observatory Broad Institute of MIT and Harvard CambridgeMA02142 United States Howard Hughes Medical Institute Koch Institute of Integrative Cancer Research Department of Biology Massachusetts Institute of Technology CambridgeMA02140 United States New York Genome Center New York CityNY10013 United States New York University New YorkNY10012 United States Department of Biomedical Informatics Harvard Medical School BostonMA02115 United States Department of Genome Sciences University of Washington SeattleWA98105 United States Department of Chemistry Purdue University West LafayetteIN47907 United States Department of Biochemistry Stanford University School of Medicine StanfordCA94305 United States Pittsburgh Supercomputing Center Carnegie Mellon University PittsburghPA15213 United States Department of Computational Biology School of Computer Science Carnegie Mellon University PittsburghPA15213 United States Department of Bioengineering University of California San Diego La JollaCA92093 United States Department of Intelligent Systems Engineering School of Informatics Computing and Engineering Indiana University BloomingtonIN47408 United States Department of Surgery Washington University School of Medicine St LouisMO63110 United States Division of Program Coordination Planning and Strategic Initiatives National Institutes of Health BethesdaMD20892 United States National Human Genome Research Institute National Institutes of Health BethesdaMD20892 United States National Heart Lung and Blood Institute National Institutes of Health BethesdaMD20892 United States Caltech-UW TMC Departmen

Transformative technologies are enabling the construction of three dimensional (3D) maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible 3D molecular and cellular atlas of the human body, in health and various disease settings. Copyright © 2019, The Authors. All rights reserved.

关键词： Mapping

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Quantum Games and Interactive Tools for Quantum Technologies Outreach and Education

arXiv

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arXiv 2022年

作者： Seskir, Zeki C. Migdal, Piotr Weidner, Carrie Anupam, Aditya Case, Nicky Davis, Noah Decaroli, Chiara Ercan, İlke Foti, Caterina Gora, Pawel Jankiewicz, Klementyna La Cour, Brian R. Malo, Jorge Yago Maniscalco, Sabrina Naeemi, Azad Nita, Laurentiu Parvin, Nassim Scafirimuto, Fabio Sherson, Jacob F. Surer, Elif Wootton, James Yeh, Lia Zabello, Olga Chiofalo, Marilù Karlsruhe Institute of Technology ITAS Karlstraße 11 Karlsruhe76133 Germany Quantum Flytrap ul. Ceglowska 29 Warsaw01-809 Poland Quantum Engineering Technology Laboratories H.H. Wills Physics Laboratory Department of Electrical and Electronic Engineering University of Bristol BristolBS8 1FD United Kingdom Georgia Institute of Technology School of Literature Media and Communication 686 Cherry St NW AtlantaGA30313 United States The University of Texas at Austin Center for Quantum Research Applied Research Laboratories 10000 Burnet Rd AustinTX78758 United States National Quantum Computing Center Oxfordshire DidcotOX11 0GD United Kingdom TU Delft Department of Microelectronics Mekelweg 4 Delft2628 CD Netherlands QPlayLearn Aalto University InstituteQ - The Finnish Quantum Institute Department of Applied Physics AaltoFI-00076 11000 Finland Quantum AI Foundation Sanocka 9/103 Warsaw02-110 Poland University of Pisa Department of Physics Largo Bruno Pontecorvo 3 PisaI-56126 Italy University of Helsinki InstituteQ - The Finnish Quantum Institute Department of Physics Helsinki Finland Georgia Institute of Technology School of Electrical and Computer Engineering 777 Atlantic Drive NW AtlantaGA30332 United States Quarks Interactive Strada Bailor 93a Miercurea-Ciuc Harghita4500 Romania IBM Quantum IBM Research - Zurich Säumerstrasse 4 Rüschlikon8803 Switzerland ScienceAtHome Fuglesangs Allé 4 Aarhus8210 Denmark Aarhus University Institute for Physics and Astronomy Ny Munkegade 120 Aarhus8000 Denmark Middle East Technical University Graduate School of Informatics Department of Modeling and Simulation Üniversiteler Mah. Dumlupınar Blv. No:1 Ankara06800 Turkey University of Oxford Department of Computer Science Wolfson Building Parks Road OxfordOX1 3QD United Kingdom IBM Quantum IBM T. J. Watson Research Center Yorktown HeightsNY10598 United States Offenburg University of Applied Sciences Department of Business and Industrial Eng

In this article, we provide an extensive overview of a wide range of quantum games and interactive tools that have been employed by the community in recent years. The paper presents selected tools, as described by their developers. The list includes Hello Quantum, Hello Qiskit, Particle in a Box, Psi and Delta, QPlayLearn, Virtual Lab by Quantum Flytrap, Quantum Odyssey, ScienceAtHome, and The Virtual Quantum Optics Laboratory. Additionally, we present events for quantum game development: hackathons, game jams, and semester projects. Furthermore, we discuss the Quantum Technologies Education for Everyone (QUTE4E) pilot project, which illustrates an effective integration of these interactive tools with quantum outreach and education activities. Finally, we aim at providing guidelines for incorporating quantum games and interactive tools in pedagogic materials to make quantum technologies more accessible for a wider population. Copyright © 2022, The Authors. All rights reserved.

关键词： Quantum optics

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Learn2Reg: comprehensive multi-task medical image registration challenge, dataset and evaluation in the era of deep learning

arXiv

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arXiv 2021年

作者： Hering, Alessa Hansen, Lasse Mok, Tony C.W. Chung, Albert C.S. Siebert, Hanna Häger, Stephanie Lange, Annkristin Kuckertz, Sven Heldmann, Stefan Shao, Wei Vesal, Sulaiman Rusu, Mirabela Sonn, Geoffrey Estienne, Théo Vakalopoulou, Maria Han, Luyi Huang, Yunzhi Yap, Pew-Thian Brudfors, Mikael Balbastre, Yaël Joutard, Samuel Modat, Marc Lifshitz, Gal Raviv, Dan Lv, Jinxin Li, Qiang Jaouen, Vincent Visvikis, Dimitris Fourcade, Constance Rubeaux, Mathieu Pan, Wentao Xu, Zhe Jian, Bailiang De Benetti, Francesca Wodzinski, Marek Gunnarsson, Niklas Sjölund, Jens Grzech, Daniel Qiu, Huaqi Li, Zeju Thorley, Alexander Duan, Jinming Großbröhmer, Christoph Hoopes, Andrew Reinertsen, Ingerid Xiao, Yiming Landman, Bennett Huo, Yuankai Murphy, Keelin Lessmann, Nikolas van Ginneken, Bram Dalca, Adrian V. Heinrich, Mattias P. Institute of Medical Informatics Universität zu Lübeck Ratzeburger Allee 160 Lübeck23562 Germany Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany Department of Radiology and Nuclear Medicine Radboud University Medical Center GA Nijmegen6525 Netherlands The Institute of Medical Informatics Universität zu Lübeck Lübeck23562 Germany The Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong The Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany The Department of Radiology Stanford University StanfordCA94305 United States The Department of Urology Stanford University StanfordCA94305 United States The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette 91190 France Université Paris-Saclay Institut Gustave Roussy Inserm Radiothérapie Moléculaire et Innovation Thérapeutique Villejuif94800 France The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette91190 France The Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen6525 GA Netherlands The School of Automation Nanjing University of Information Science and Technology Nanjing210044 China The School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom The Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital United States Harvard Medical School Boston United States The King’s College London United Kingdom The Tel Aviv University The Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology Hubei Wuhan430074 China MoE Key Laboratory for Biomedical Photonics Collaborative Innovation Center for Biomedical Engineering School of Engineering Sciences Huazhong University of Sci

Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medical image registration approaches on a wide range of clinically relevant tasks. This limits the development of registration methods, the adoption of research advances into practice, and a fair benchmark across competing approaches. The Learn2Reg challenge addresses these limitations by providing a multi-task medical image registration data set for comprehensive characterisation of deformable registration algorithms. A continuous evaluation will be possible at https://***. Learn2Reg covers a wide range of anatomies (brain, abdomen, and thorax), modalities (ultrasound, CT, MR), availability of annotations, as well as intra- and inter-patient registration evaluation. We established an easily accessible framework for training and validation of 3D registration methods, which enabled the compilation of results of over 65 individual method submissions from more than 20 unique teams. We used a complementary set of metrics, including robustness, accuracy, plausibility, and runtime, enabling unique insight into the current state-of-the-art of medical image registration. This paper describes datasets, tasks, evaluation methods and results of the challenge, as well as results of further analysis of transferability to new datasets, the importance of label supervision, and resulting bias. While no single approach worked best across all tasks, many methodological aspects could be identified that push the performance of medical image registration to new state-of-the-art performance. Furthermore, we demystified the common belief that conventional registration methods have to be much slower than deep-learning-based methods. © 2021, CC BY.

关键词： Image registration

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Galactic transient sources with the Cherenkov Telescope Array Observatory

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Monthly Notices of the Royal Astronomical Society 2025年第1期540卷 205–238页

作者： Abe, K Abe, S Abhir, J Abhishek, A Acero, F Acharyya, A Adam, R Aguasca-Cabot, A Agudo, I Aguirre-Santaella, A Alfaro, J Alfaro, R Alvarez-Crespo, N Alves Batista, R Amans, J-P Amato, E Ambrosi, G Ambrosino, F Angüner, E O Antonelli, L A Aramo, C Arcaro, C Arnesen, T T H Asano, K Ascasibar, Y Aschersleben, J Ashkar, H Augusto Stuani, L Baack, D Backes, M Balazs, C Balbo, M Baquero Larriva, A Barbosa Martins, V Barres de Almeida, U Barrio, J A Barrios-Jiménez, L Batković, I Batzofin, R Baxter, J Becerra González, J Becker Tjus, J Belmont, R Benbow, W Bernete, J Bernlöhr, K Berti, A Bertucci, B Beshley, V Bhattacharjee, P Bhattacharyya, S Bigongiari, C Bissaldi, E Blanch, O Blazek, J Bocchino, F Boisson, C Bolmont, J Bonnoli, G Bonollo, A Bordas, P Bosnjak, Z Bottacini, E Böttcher, M Bradascio, F Bronzini, E Brown, A M Brunelli, G Bulgarelli, A Burelli, I Burger-Scheidlin, C Burmistrov, L Burton, M Buscemi, M Cailleux, J Campoy-Ordaz, A Cantlay, B K Capasso, G Caproni, A Capuzzo-Dolcetta, R Caraveo, P Caroff, S Carosi, A Carosi, R Carquin, E Carrasco, M-S Cascone, E Cassol, F Castaldini, L Castrejon, N Castro-Tirado, A J Cerasole, D Ceribella, G Cerruti, M Chadwick, P M Chaty, S Chen, A W Chernyakova, M Chiavassa, A Chudoba, J Chytka, L Cicciari, G M Cifuentes, A Coimbra Araujo, C H Colapietro, M Conforti, V Contreras, J L Cortina, J Costa, A Costantini, H Cotter, G Cristofari, P Cuevas, O Curtis-Ginsberg, Z D’Aì, A D’Amico, G D’Ammando, F Dai, S Dazzi, F de Bony de Lavergne, M De Caprio, V De Cesare, G De Frondat Laadim, F de Gouveia Dal Pino, E M De Lotto, B De Lucia, M de Martino, D de Menezes, R de Naurois, M de Ona Wilhelmi, E de Souza, V del Peral, L del Valle, M V Delgado, C Dell’aiera, M Della Valle, M della Volpe, D Depaoli, D Devin, J Di Girolamo, T Di Piano, A Di Pierro, F Di Tria, R Di Venere, L Diebold, S Dignam, C Dima, R Dinesh, A Djuvsland, J Dominik, R M Dominis Prester, D Donini, A Dorner, D Dörner, J Doro, M Dubos, C Ducci, L Dwarkadas, V V Ebr, J Eckner, C Egberts, K Einecke, S Elsässer, D Emery Department of Physics Tokai University 4-1-1 Kita-Kaname Hiratsuka Kanagawa 259-1292 Japan Institute for Cosmic Ray Research University of Tokyo 5-1-5 Kashiwa-no-ha Kashiwa Chiba 277-8582 Japan ETH Zürich Institute for Particle Physics and Astrophysics Otto-Stern-Weg 5 CH-8093 Zürich Switzerland INFN and Università degli Studi di Siena Dipartimento di Scienze Fisiche della Terra e dell’Ambiente (DSFTA) Sezione di Fisica Via Roma 56 I-53100 Siena Italy Université Paris-Saclay Université Paris Cité CEA CNRS AIM F-91191 Gif-sur-Yvette Cedex France FSLAC IRL 2009 CNRS/IAC E-38205 La Laguna Tenerife Spain University of Alabama Tuscaloosa Department of Physics and Astronomy Gallalee Hall Box 870324 Tuscaloosa AL 35487-0324 USA Université Côte d’Azur Observatoire de la Côte d’Azur CNRS Laboratoire Lagrange UF 06304 Nice France Laboratoire Leprince-Ringuet CNRS/IN2P3 École Polytechnique Institut Polytechnique de Paris F-91120 Palaiseau France Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Martí i Franquès 1 E-08028 Barcelona Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n E-18008 Granada Spain Institute for Computational Cosmology and Department of Physics Durham University South Road Durham DH1 3LE UK Pontificia Universidad Católica de Chile Av. Libertador Bernardo O’Higgins 340 8331150 Santiago Chile Universidad Nacional Autónoma de México Delegación Coyoacán 04510 Ciudad de México Mexico IPARCOS-UCM Instituto de Física de Partículas y del Cosmos and EMFTEL Department Universidad Complutense de Madrid E-28040 Madrid Spain Instituto de Física Teórica UAM/CSIC and Departamento de Física Teórica Universidad Autónoma de Madrid c/ Nicolás Cabrera 13-15 Campus de Cantoblanco UAM E-28049 Madrid Spain LUTH GEPI and LERMA Observatoire de Paris Université PSL Université Paris Cité CNRS 5 place Jules Janssen F-92190 Meudon France INAF – Osservatorio

A wide variety of Galactic sources show transient emission at soft and hard X-ray energies: low- and high-mass X-ray binaries containing compact objects, isolated neutron stars exhibiting extreme variability as magnetars as well as pulsar-wind nebulae. Although most of them can show emission up to MeV and/or GeV energies, many have not yet been detected in the TeV domain by Imaging Atmospheric Cherenkov Telescopes. In this paper, we explore the feasibility of detecting new Galactic transients with the Cherenkov Telescope Array Observatory (CTAO) and the prospects for studying them with Target of Opportunity observations. We show that CTAO will likely detect new sources in the TeV regime, such as the massive microquasars in the Cygnus region, low-mass X-ray binaries with low-viewing angle, flaring emission from the Crab pulsar-wind nebula or other novae explosions, among others. Since some of these sources could also exhibit emission at larger time-scales, we additionally test their detectability at longer exposures. We finally discuss the multiwavelength synergies with other instruments and large astronomical facilities.

关键词： binaries: general stars: magnetars novae cataclysmic variables pulsars: general gamma-rays: general

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Federated Learning Enables Big Data for Rare Cancer Boundary Detection

arXiv

引用

arXiv 2022年

作者： Pati, Sarthak Baid, Ujjwal Edwards, Brandon Sheller, Micah Wang, Shih-Han Reina, G. Anthony Foley, Patrick Gruzdev, Alexey Karkada, Deepthi Davatzikos, Christos Sako, Chiharu Ghodasara, Satyam Bilello, Michel Mohan, Suyash Vollmuth, Philipp Brugnara, Gianluca Preetha, Chandrakanth J. Sahm, Felix Maier-Hein, Klaus Zenk, Maximilian Bendszus, Martin Wick, Wolfgang Calabrese, Evan Rudie, Jeffrey Villanueva-Meyer, Javier Cha, Soonmee Ingalhalikar, Madhura Jadhav, Manali Pandey, Umang Saini, Jitender Garrett, John Larson, Matthew Jeraj, Robert Currie, Stuart Frood, Russell Fatania, Kavi Huang, Raymond Y. Chang, Ken Balana, Carmen Capellades, Jaume Puig, Josep Trenkler, Johannes Pichler, Josef Necker, Georg Haunschmidt, Andreas Meckel, Stephan Shukla, Gaurav Liem, Spencer Alexander, Gregory S. Lombardo, Joseph Palmer, Joshua D. Flanders, Adam E. Dicker, Adam P. Sair, Haris I. Jones, Craig K. Venkataraman, Archana Jiang, Meirui So, Tiffany Y. Chen, Cheng Heng, Pheng Ann Dou, Qi Kozubek, Michal Lux, Filip Michálek, Jan Matula, Petr Keřkovský, Miloš Kopřivová, Tereza Dostál, Marek Vybíhal, Václav Vogelbaum, Michael A. Mitchell, J. Ross Farinhas, Joaquim Maldjian, Joseph A. Yogananda, Chandan Ganesh Bangalore Pinho, Marco C. Reddy, Divya Holcomb, James Wagner, Benjamin C. Ellingson, Benjamin M. Cloughesy, Timothy F. Raymond, Catalina Oughourlian, Talia Hagiwara, Akifumi Wang, Chencai To, Minh-Son Bhardwaj, Sargam Chong, Chee Agzarian, Marc Falcão, Alexandre Xavier Martins, Samuel B. Teixeira, Bernardo C.A. Sprenger, Flávia Menotti, David Lucio, Diego R. LaMontagne, Pamela Marcus, Daniel Wiestler, Benedikt Kofler, Florian Ezhov, Ivan Metz, Marie Jain, Rajan Lee, Matthew Lui, Yvonne W. McKinley, Richard Slotboom, Johannes Radojewski, Piotr Meier, Raphael Wiest, Roland Derrick, Murcia Fu, Eric Haas, Rourke Thompson, John Ormond, David Ryan Badve, Chaitra Sloan, Andrew E. Vadmal, Vachan Waite, Kristin Colen, Rivka R. Pei, Linmin Ak, Murat Srinivasan, Ashok Bapuraj, J. Rajiv Rao, Arvind Wang, Nicholas Yoshiaki, Ota Moritani, Tos University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Informatics Technical University of Munich Bavaria Munich Germany Intel Corporation Santa ClaraCA United States Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Department of Neuroradiology Heidelberg University Hospital Heidelberg Germany Heidelberg Germany Department of Neuropathology Heidelberg University Hospital Heidelberg Germany Division of Medical Image Computing German Cancer Research Center Heidelberg Germany Neurology Clinic Heidelberg University Hospital Heidelberg Germany Department of Radiology & Biomedical Imaging University of California San Francisco San FranciscoCA United States Symbiosis Center for Medical Image Analysis Symbiosis International University Maharashtra Pune India Department of Neuroimaging and Interventional Radiology National Institute of Mental Health and Neurosciences Karnataka Bangalore India Department of Radiology School of Medicine and Public Health University of Wisconsin MadisonWI United States Department of Medical Physics School of Medicine and Public Health University of Wisconsin MadisonWI United States Department of Neuroradiology Clinical Neuroscience Center University Hospital Zurich University of Zurich Zurich Switzerland Leeds Teaching Hospitals Trust Department of Radiology Leeds United Kingdom Department of Radiology Brigham and Women's Hospital Harvard Medical School BostonMA United States Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital CharlestownMA United States Catalan Institute of Oncology Badalona Spain Consorci MAR Parc de Salut de Barcelona Catalonia Spain Josep Trueta University Hospital Girona Spain

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple sites. However, such centralization is challenging to scale (or even not feasible) due to various limitations. Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here we present findings from the largest FL study to-date, involving data from 71 healthcare institutions across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, utilizing the largest dataset of such patients ever used in the literature (25,256 MRI scans from 6,314 patients). We demonstrate a 33% improvement over a publicly trained model to delineate the surgically targetable tumor, and 23% improvement over the tumor's entire extent. We anticipate our study to: 1) enable more studies in healthcare informed by large and diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further quantitative analyses for glioblastoma via performance optimization of our consensus model for eventual public release, and 3) demonstrate the effectiveness of FL at such scale and task complexity as a paradigm shift for multi-site collaborations, alleviating the need for data sharing. © 2022, CC BY.

关键词： Tumors

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