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Empirical testing: The prototyper's evaluation mechanism

NAVAL ENGINEERS JOURNAL 1997年第1期109卷 41-46页

作者： Hafner, AN Arnold N. Hafner Ph.D.:is founder and president of Information Systems Research (ISR). He has twenty-five years of experience in systems development and is published in the field of systems development management. He served as corporate research scientist at Systems Exploration Inc. from 1988 to 1991 program director at Computer Science Corporation from 1983 to 1988 director of operations at Republic Management Systems Corporation from 1981 to 1983 and program manager at Computer Science Corporation from 1972 to 1981. A 1962 graduate of the US. Naval Academy he holds a doctoral degree in human behavior and engineering degrees in electronics and communications. He has taught courses on information systems and systems management at most of the colleges in the San Diego area. Dr. Hafner has presented fourteen refereed research papers while publishing sixteen articles and a book A Manager's Guide to Software System Development.

Evaluating complex systems is the subject of this paper, the third in a series investigating prototyping. It provides an interesting and helpful overview of how to evaluate systems prototypes and outlines the iterative stream of developer-user interactions that is replacing older approaches to testing and evaluating new military systems, which promise to reduce the time required to develop and field future military capabilities. Changes to the acquisition process, such as those the paper sketches, will facilitate the nation's rapid transit through its current revolution in military affairs.

关键词： Systems analysis

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Manipulating Fano coupling in an opto-thermoelectric field

arXiv

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arXiv 2024年

作者： Lin, Linhan Lepeshov, Sergey Krasnok, Alex Huang, Yu Jiang, Taizhi Peng, Xiaolei Korgel, Brian A. Alu, Andrea Zheng, Yuebing State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instrument Tsinghua University Beijing100084 China Department of Electrical and Photonics Engineering DTU Electro Technical University of Denmark Building 343 Kgs. LyngbyDK-2800 Denmark Department of Electrical and Computer Engineering Florida International University MiamiFL33174 United States School of Physics and Electronics Hunan University Changsha410082 China Mc Ketta Department of Chemical Engineering The University of Texas at Austin AustinTX78712 United States Materials Science & Engineering Program Texas Materials Institute The University of Texas at Austin AustinTX78712 United States Department of Electrical and Computer Engineering The University of Texas at Austin AustinTX78712 United States Advanced Science Research Center City University of New York New YorkNY10031 United States Physics Program Graduate Center City University of New York NY10016 United States Walker Department of Mechanical Engineering The University of Texas at Austin AustinTX78712 United States

Fano resonances in photonics arise from the coupling and interference between two resonant modes in structures with broken symmetry. They feature an uneven and narrow and tunable lineshape, and are ideally suited for optical spectroscopy. Many Fano resonance structures have been suggested in nanophotonics over the last ten years, but reconfigurability and tailored design remain challenging. Herein, we propose an all-optical "pick-and-place" approach aimed at assemble Fano metamolecules of various geometries and compositions in a reconfigurable manner. We study their coupling behavior by in-situ dark-field scattering spectroscopy. Driven by a light-directed opto-thermoelectric field, silicon nanoparticles with high quality-factor Mie resonances (discrete states) and low-loss BaTiO3 nanoparticles (continuum states) are assembled into all-dielectric heterodimers, where distinct Fano resonances are observed. The Fano parameter can be adjusted by changing the resonant frequency of the discrete states or the light polarization. We also show tunable coupling strength and multiple Fano resonances by altering the number of continuum states and discrete states in dielectric heterooligomers. Our work offers a general design rule for Fano resonance and an all-optical platform for controlling Fano coupling on demand. Copyright © 2024, The Authors. All rights reserved.

关键词： Light polarization

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Vacuum Ultraviolet Light-Generating Metalens

Vacuum Ultraviolet Light-Generating Metalens

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Pacific Rim Conference on Lasers and Electro-Optics (CLEO/Pacific Rim)

作者： Ming Lun Tseng Michael Semmlinger Ming Zhang Catherine Arndt Tzu-Ting Huang Jian Yang Hsin Yu Kuo Vin-Cent Su Mu Ku Chen Cheng Hung Chu Benjamin Cerjan Din Ping Tsai Peter Nordlander Naomi J. Halas Institute of Electronics National Yang Ming Chiao Tung University Hsinchu Taiwan Research Center for Applied Sciences Academia Sinica Taipei Taiwan Department of Electrical and Computer Engineering Rice University Houston Texas USA Laboratory for Nanophotonics Rice University Houston Texas USA Applied Physics Graduate Program Rice University Houston Texas USA Department of Physics and Astronomy Rice University Houston Texas USA Department of Physics National Taiwan University Taipei Taiwan Department of Electrical Engineering National United University Miaoli Taiwan Department of Electrical Engineering City University of Hong Kong Kowloon Hong Kong Department of Chemistry Rice University Houston Texas USA

Vacuum ultraviolet (VUV) light is of great importance to many applications such as photochemistry and nanolithography. In this talk, a nonlinear metalens composed of ZnO nanoantennas for VUV generation and focusing wi...

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The Form of High-Performance Computing: A Survey

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IOP Conference Series: Materials Science and engineering 2019年第5期662卷

作者： Priati Assiroj H L H S Warnars R Kosala B Ranti S Supangat A I Kistijantoro E Abdurrachman Binus Graduate Program Doctor of Computer Science Bina Nusantara University Jakarta Information System Dept. Buana Perjuangan University Karawang Computer Science Department BINUS Graduate Program Doctor of Computer Science Bina Nusantara University Jakarta Information System Department Bina Nusantara University Jakarta Information System Technology Department Institut Teknologi Bandung School of Electronics Engineering and Informatics Institut Teknologi Bandung

Computational technology is an important thing that needed in the whole of human life. Along with the development of computer technology, there are a significant data created and wait to be processed; we will get more advantages if it well-processed, if not we will see the data explosion, the data is just a useless stack. Research mitigates the other research paper and makes a conclusion and a report by PRISMA method. The development of computer technology will support the development of an organization. Considering any factors in choosing the right and suitable high-performance computer resource due to our organization is a must. The existing high-performance computing forms are Supercomputer, Grid Computing, Cluster Computing, and Cloud Computing. Based on this work, the last form of high-performance computing, Cloud Computing is one of the most used forms thus we mitigate its advantages and disadvantages. Recently, to process this vast data, we must have a high-performance computer and to provide it, this is not a cheap resource.

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Gene knockout inference with variational graph autoencoder learning single-cell gene regulatory networks

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Nucleic acids research 2023年第13期51卷 6578-6592页

作者： Yongjian Yang Guanxun Li Yan Zhong Qian Xu Bo-Jia Chen Yu-Te Lin Robert S Chapkin James J Cai Department of Electrical and Computer Engineering Texas A&M University College Station TX 77843 USA. Department of Statistics Texas A&M University College Station TX 77843 USA. Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of Statistics East China Normal University 3663 North Zhongshan Road Shanghai 200062 China. Department of Veterinary Integrative Biosciences Texas A&M University College Station TX 77843 USA. Graduate Institute of Microbiology and Public Health College of Veterinary Medicine National Chung Hsing University Taichung 402 Taiwan. Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan. Program in Integrative & Complex Diseases Department of Nutrition Texas A&M University College Station TX 77843 USA. Interdisciplinary Program of Genetics Texas A&M University College Station TX 77843 USA.

In this paper, we introduce Gene Knockout Inference (GenKI), a virtual knockout (KO) tool for gene function prediction using single-cell RNA sequencing (scRNA-seq) data in the absence of KO samples when only wild-type (WT) samples are available. Without using any information from real KO samples, GenKI is designed to capture shifting patterns in gene regulation caused by the KO perturbation in an unsupervised manner and provide a robust and scalable framework for gene function studies. To achieve this goal, GenKI adapts a variational graph autoencoder (VGAE) model to learn latent representations of genes and interactions between genes from the input WT scRNA-seq data and a derived single-cell gene regulatory network (scGRN). The virtual KO data is then generated by computationally removing all edges of the KO gene-the gene to be knocked out for functional study-from the scGRN. The differences between WT and virtual KO data are discerned by using their corresponding latent parameters derived from the trained VGAE model. Our simulations show that GenKI accurately approximates the perturbation profiles upon gene KO and outperforms the state-of-the-art under a series of evaluation conditions. Using publicly available scRNA-seq data sets, we demonstrate that GenKI recapitulates discoveries of real-animal KO experiments and accurately predicts cell type-specific functions of KO genes. Thus, GenKI provides an in-silico alternative to KO experiments that may partially replace the need for genetically modified animals or other genetically perturbed systems.

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AUTOMATION OF PROPELLER INSPECTION AND FINISHING

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NAVAL ENGINEERS JOURNAL 1985年第4期97卷 124-131页

作者： STERN, H METZGER, R Howard K. Stern:is presently vice president of Robotic Vision Systems Inc. He received a bachelor of electrical engineering degree from College of the City of New York in 1960. Mr. Stern joined Dynell Electronics Corporation in 1971 and became part of the Robotic Vision Systems Inc. staff at the time of its spin-off from Dynell. He was program manager of the various three-dimensional sensing and replication systems constructed by Dynell and Robotic Vision Systems. As program manager his responsibilities encompassed technical administrative and operational areas. The first two portrait sculpture studio systems and the first three replication systems built by Robotic Vision Systems Inc. were designed manufactured and operated under his direction. Before joining Dynell Mr. Stern was a senior engineer at Instrument Systems Corporation and chief engineer of the Special Products Division of General Instrument Corporation. Prior to these positions Mr. Stern was chief engineer of Edo Commercial Corporation. At General Instrument and Edo Commercial he was responsible for the design and manufacture of military and commercial avionics equipment. Mr. Stern is presently responsible for directing the systems design and development for all of the company's programs. Robert J. Metzger:is currently engineering group leader at Robotic Vision Systems Inc. He graduated summa cum laude from the Cooper Union in 1972 with a bachelor of electrical engineering degree. Under sponsorship of a National Science Foundation graduate fellowship he graduated from the Massachusetts Institute of Technology in 1974 with the degrees of electrical engineer and master of science (electrical engineering). In 1979 Mr. Metzger graduated from Polytechnic Institute of New York with the degree of master of science (computer science). Since 1974 Mr. Metzger has been actively engaged in the design of systems and software for noncontact threedimensional optical measurement for both military and commercial applications. Of particular note are his c

Ship's propellers are currently measured by manual procedures using pitchometers, templates and gauges. This measurement process is extremely tedious, labor intensive and time consuming. In an effort to provide increased accuracy, repeatability and cost effectiveness in propeller manufacture, an automated propeller optical measurement system (APOMS) has been built which rapidly and automatically scans an entire ship's propeller using a 3-D vision sensor. This equipment is integrated with a propeller robotic automated templating system (PRATS) and the propeller optical finishing system (PROFS) which robotically template and grind the propeller to its final shape, using the APOMS-derived data for control feedback. The optical scanning and the final shape are both controlled by CAD/CAM data files describing the desired propeller shape. An automated propeller balancing system is incorporated into the PROFS equipment. The APOMS/PRATS/PROFS equipment is expected to provide lower propeller manufacturing costs.

关键词： PROPELLERS

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Development of a Selective Wet-Chemical Etchant for 3D Structuring of Silicon via Nonlinear Laser Lithography

arXiv

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arXiv 2023年

作者： Borra, Mona Zolfaghari Radfar, Behrad Nasser, Hisham Çolakoğlu, Tahir Tokel, Onur Turnalı, Ahmet Demirtaş, Merve Ustunel, Hande Toffoli, Daniele Ömer İlday, F. Turan, Raşit Pavlov, Ihor Bek, Alpan ODTÜ-GÜNAM Middle East Technical University Ankara06800 Turkey Ankara06800 Turkey Department of Electronics and Nanoengineering Aalto University Tietotie 3 EspooFI-02150 Finland Department of Physics Engineering Ankara University Ankara06100 Turkey Department of Physics Bilkent University Ankara06800 Turkey UNAM National Nanotechnology Research Center Institute of Materials Science and Nanotechnology Bilkent University Ankara06800 Turkey Department of Electrical and Electronics Engineering Bilkent University Ankara06800 Turkey Department of Electrical and Computer Engineering Boston University 8 Saint Mary’s Street BostonMA02215 United States Ankara06800 Turkey Network Technologies Department TUBITAK ULAKBIM Ankara06800 Turkey Department of Chemical and Pharmaceutical Sciences Trieste University Trieste Italy IOM-CNR Istituto Officina dei Materiali Trieste34149 Italy Micro and Nanotechnology Graduate Program of Natural and Applied Sciences Middle East Technical Turkey

Recently-demonstrated high-quality three-dimensional (3D) subsurface laser processing inside crystalline silicon (c-Si) wafers opens a door to a wide range of novel applications in multidisciplinary research areas. Using this technique, a novel maskless micro-pillars with precise control on the surface reflection and coverage are successfully fabricated by etching the laser processed region of c-Si wafer. To achieve this, a particular selective wet chemical etching is developed to follow subsurface laser processing of c-Si to reveal the desired 3D structures with smooth surfaces. Here, we report the development of a novel chromium-free chemical etching recipe based on copper nitrate, which yields substantially smooth surfaces at high etch rate and selectivity on the both laser-processed Si surface and subsurface, i.e., without significant etching of the unmodified Si. Our results show that the etch rate and surface morphology are interrelated and strongly influenced by the composition of the adopted etching solution. After an extensive compositional study performed at room temperature, we identify an etchant with a selectivity of over 1600 times for laser-modified Si with respect to unmodified Si. We also support our findings using density functional theory calculations of HF and Cu adsorption energies, indicating significant diversity on the c-Si and laser-modified surfaces. Copyright © 2023, The Authors. All rights reserved.

关键词： Morphology

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A web-based, hospital-wide health care-associated bloodstream infection surveillance and classification system: Development and evaluation

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JMIR Medical Informatics 2015年第3期3卷 e31页

作者： Tseng, Yi-Ju Wu, Jung-Hsuan Lin, Hui-Chi Chen, Ming-Yuan Ping, Xiao-Ou Sun, Chun-Chuan Shang, Rung-Ji Sheng, Wang-Huei Chen, Yee-Chun Lai, Feipei Chang, Shan-Chwen Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan Computational Health Informatics Program Boston Children's Hospital Boston MA United States Department of Electrical Engineering National Taiwan University Taipei Taiwan Center for Infection Control National Taiwan University Hospital Taipei Taiwan National Taiwan University Hospital Information Systems Office Taipei Taiwan Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Department of Internal Medicine National Taiwan University Hospital and College of Medicine Taipei Taiwan National Health Research Institutes National Institute of Infectious Diseases and Vaccinology Miaoli Taiwan

Background: Surveillance of health care-associated infections is an essential component of infection prevention programs, but conventional systems are labor intensive and performance dependent. Objective: To develop an automatic surveillance and classification system for health care-associated bloodstream infection (HABSI), and to evaluate its performance by comparing it with a conventional infection control personnel (ICP)-based surveillance system. Methods: We developed a Web-based system that was integrated into the medical information system of a 2200-bed teaching hospital in Taiwan. The system automatically detects and classifies HABSIs. Results: In this study, the number of computer-detected HABSIs correlated closely with the number of HABSIs detected by ICP by department (n=20;r=.999 P<.001) and by time (n=14;r=.941;P<.001). Compared with reference standards, this system performed excellently with regard to sensitivity (98.16%), specificity (99.96%), positive predictive value (95.81%), and negative predictive value (99.98%). The system enabled decreasing the delay in confirmation of HABSI cases, on average, by 29 days. Conclusions: This system provides reliable and objective HABSI data for quality indicators, improving the delay caused by a conventional surveillance system. © 2020 JMIR Publications Inc. All rights reserved.

关键词： Health care-associated infection Infection control Information systems Surveillance Web-based services

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FULL-WAVE SOLUTION OF DIELECTRIC LOADED WAVE-GUIDES AND SHIELDED MICROSTRIPS UTILIZING FINITE-DIFFERENCE AND THE CONJUGATE-GRADIENT METHOD

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INTERNATIONAL JOURNAL OF MICROWAVE AND MILLIMETER-WAVE computer-AIDED engineering 1991年第4期1卷 346-357页

作者： NARAYANAN, V MANELA, M LADE, RK SARKAR, TK Department of Electrical and Computer Engineering Syracuse University Syracuse New York 13244-1240 Viswanathan Narayanan was born in Bangalore India on December 14 1965. He received the BE degree in Electronics and Communications from B.M.S. College of Engineering Bangalore in 1988. He joined the Department of Electrical Engineering at Syracuse University for his graduate studies in 1989 where he is currently a research assistant. His research interests are in microwave measurements numerical electromagnetics and signal processing. Biographies and photos are not available for M. Manela and R. K. Lade. Tapan K. Sarkar (Sf69-M'76-SM'X1) was born in Calcutta. India on August 2 1948. He received the BTech degree from the Indian Institute of Technology Kharagpur India in 1969 the MScE degree from the University of New Brunswick Fredericton Canada in 1971. and the MS and PhD degrees from Syracuse University. Syracuse NY in 1975. From 1975-1976 he was with the TACO Division of the General Instruments Corporation. He was with the Rochester Institute of Technology (Rochester NY) from 1976-1985. He was a Research Fellow at the Gordon Mckay Laboratory Harvard University Cambridge MA from 1977 to 1978. He is now a Professor in the Department of Electrical and Computer Engineering Syracuse University. His current research interests deal with numerical solutions of operator equations arising in electromagnetics and signal processing with application to system design. He obtained one of the “ best solution” awards in May 1977 at the Rome Air Development Center (RADC) Spectral Estimation Workshop. He has authored or coauthored more than 154 journal articles and conference papers and has written chapters in eight books. Dr. Sarkar is a registered professional engineer in the state of New York. He received the Best Paper Award of the IEEE Transactions on Electromagnetic Compatibility in 1979. He was an Associate Editor for feature articles of the lEEE Antennas arid Propagation Sociefy Newsletter and was

Dynamic analysis of waveguide structures containing dielectric and metal strips is presented. The analysis utilizes a finite difference frequency domain procedure to reduce the problem to a symmetric matrix eigenvalue problem. Since the matrix is also sparse, the eigenvalue problem can be solved quickly and efficiently using the conjugate gradient method resulting in considerable savings in computer storage and time. Comparison is made with the analytical solution for the loaded dielectric waveguide case. For the microstrip case, we get both waveguide modes and quasi-TEM modes. The quasi-TEM modes in the limit of zero frequency are checked with the static analysis which also uses finite difference. Some of the quasi-TEM modes are spurious. This article describes their origin and discusses how to eliminate them. Numerical results are presented to illustrate the principles.

关键词： Waveguides

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Human brain mapping with multi-thousand channel PtNRGrids resolves novel spatiotemporal dynamics

arXiv

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arXiv 2021年

作者： Tchoe, Youngbin Bourhis, Andrew M. Cleary, Daniel R. Stedelin, Brittany Lee, Jihwan Tonsfeldt, Karen J. Brown, Erik C. Siler, Dominic Paulk, Angelique C. Yang, Jimmy C. Oh, Hongseok Ro, Yun Goo Choi, Woojin Lee, Keundong Russman, Samantha Ganji, Mehran Galton, Ian Ben-Haim, Sharona Raslan, Ahmed M. Dayeh, Shadi A. Integrated Electronics and Biointerfaces Laboratory Department of Electrical and Computer Engineering University of California San Diego San DiegoCA92093 United States Department of Neurological Surgery University of California San Diego San DiegoCA92093 United States Department of Neurological Surgery Oregon Health & Science University Mail Code CH8N 3303 SW Bond Avenue PortlandOR97239-3098 United States Department of Obstetrics Gynecology and Reproductive Sciences Center for Reproductive Science and Medicine University of California San Diego San DiegoCA92093 United States Department of Neurology Massachusetts General Hospital BostonMA02114 United States Department of Neurosurgery Massachusetts General Hospital BostonMA02114 United States Graduate Program of Materials Science and Engineering University of California San Diego San DiegoCA92093 United States

Electrophysiological devices are critical for mapping eloquent and diseased brain regions and for therapeutic neuromodulation in clinical settings and are extensively utilized for research in brain-machine interfaces. However, the existing devices are often limited in either spatial resolution or cortical coverage, even including those with thousands of channels used in animal experiments. Here, we developed scalable manufacturing processes and dense connectorization to achieve reconfigurable thin-film, multi-thousand channel neurophysiological recording grids using platinum-nanorods (PtNRGrids). With PtNRGrids, we have achieved a multi-thousand channel array of small (30 μm) contacts with low impedance, providing unparalleled spatial and temporal resolution over a large cortical area. We demonstrate that PtNRGrids can resolve sub-millimeter functional organization of the barrel cortex in anesthetized rats that captured the histochemically-demonstrated structure. In the clinical setting, PtNRGrids resolved fine, complex temporal dynamics from the cortical surface in an awake human patient performing grasping tasks. Additionally, the PtNRGrids identified the spatial spread and dynamics of epileptic discharges in a patient undergoing epilepsy surgery at 1 mm spatial resolution, including activity induced by direct electrical stimulation. Collectively, these findings demonstrate the power of the PtNRGrids to transform clinical mapping and research with brain-machine interfaces and highlights a path toward novel therapeutics. Copyright © 2021, The Authors. All rights reserved.

关键词： Mapping

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