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Optically-generated focused ultrasound for noninvasive brain stimulation with ultrahigh precision

Light(Science & Applications) 2022年第11期11卷 2817-2831页

作者： Yueming Li Ying Jiang Lu Lan Xiaowei Ge Ran Cheng Yuewei Zhan Guo Chen Linli Shi Runyu Wang Nan Zheng Chen Yang Ji-Xin Cheng Department of Mechanical Engineering Boston UniversityBostonMA 02215USA Graduate Program for Neuroscience Boston UniversityBostonMA 02215USA Department of Electrical and Computer Engineering Boston UniversityBostonMA 02215USA Department of Chemistry Boston UniversitBostonMA 02215USA Department of Biomedical Engineering Boston UniversityBostonMA 02215USA Division of Materials Science and Engineering Boston UniversityBostonMA 02215USA Department of Biological Engineering Massachusetts Institute of TechnologyCambridgeMA 02142USA

High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological *** non-invasive neuromodulation methods offer limited precision at the milimeter ***,we report opticallygenerated focused ultrasound(OFUS)for non-invasive brain stimulation with ultrahigh *** is generated by a soft optoacoustic pad(SOAP)fabricated through embedding candle soot nanoparticles in a curved polydimethylsiloxane *** generates a transcranial ultrasound focus at 15 MHz with an ultrahigh lateral resolution of 83μm,which is two orders of magnitude smaller than that of conventional transcranial-focused ultrasound(tFUS).Here,we show effective OFUS neurostimulation in vitro with a single ultrasound *** demonstrate submillimeter transcranial stimulation of the mouse motor cortex in *** acoustic energy of 0.6 mJ/cm?,four orders of magnitude less than that of tFUS,is suffcient for successful OFUS *** offers new capabilities for neuroscience studies and disease treatments by delivering a focus with ultrahigh precision noninvasively.

关键词： SOAP stimulation precision

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Variable-Speed Teaching-Playback as Real-World Data Augmentation for Imitation Learning

arXiv

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arXiv 2024年

作者： Masuya, Nozomu Sato, Hiroshi Yamane, Koki Kusume, Takuya Sakaino, Sho Tsuji, Toshiaki Master's Program in Intelligent and Mechanical Interaction Systems Degree Programs in Systems and Information and Engineering Graduate School of Science and Technology University of Tsukuba Japan Doctoral Program in Intelligent and Mechanical Interaction Systems Degree Programs in Systems and Information and Engineering Graduate School of Science and Technology University of Tsukuba Japan Department of Intelligent Interaction Technologies Institute of Systems and Information Engineering University of Tsukuba Japan Graduate School of Science and Engineering Saitama University Saitama Japan

Because imitation learning relies on human demonstrations in hard-to-simulate settings, the inclusion of force control in this method has resulted in a shortage of training data, even with a simple change in speed. Although the field of data augmentation has addressed the lack of data, conventional methods of data augmentation for robot manipulation are limited to simulation-based methods or downsampling for position control. This paper proposes a novel method of data augmentation that is applicable to force control and preserves the advantages of real-world datasets. We applied teaching-playback at variable speeds as real-world data augmentation to increase both the quantity and quality of environmental reactions at variable speeds. An experiment was conducted on bilateral control-based imitation learning using a method of imitation learning equipped with position-force control. We evaluated the effect of real-world data augmentation on two tasks, pick-and-place and wiping, at variable speeds, each from two human demonstrations at fixed speed. The results showed a maximum 55% increase in success rate from a simple change in speed of real-world reactions and improved accuracy along the duration/frequency command by gathering environmental reactions at variable speeds. Copyright © 2024, The Authors. All rights reserved.

关键词： Demonstrations

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Pulsatile Bypass Flow by Means of Power Law and Newtonian Model: A Comparison Guided by Numerical Investigation

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Defect and Diffusion Forum 2022年 420卷 215-228页

作者： Impiombato, Andrea Natale Orlandi, Francesco Civita, Giorgio La Zinani, Flavia Schwarz Franceschini Rocha, Luiz Alberto Oliveira Biserni, Cesare Di Schio, Eugenia Rossi Department of Industrial Engineering Alma Mater Studiorum University of Bologna Viale Risorgimento 2 Bologna40136 Italy Mechanical Engineering Graduate Program Universidade do Vale do Rio dos Sinos – UNISINOS Av. Unisinos 950 RS São LeopoldoCEP 93022-750 Brazil Department of Mechanical Engineering Federal University of Rio Grande do Sul – UFRGS Sarmento Leite Street 425 RS Porto Alegre Brazil

In this work, the comparison between the Newtonian and the Power Law models was pointed out to determine the flow field within a system that includes the bypass of a narrowing zone (Stenosis) of an ideal artery. The simulations were conducted in a transient regime considering the pulsed effect inside the veins. The results show that the Power Law model does not sufficiently coincide with the Newtonian model, especially for describing the wall stresses. More specifically, the Power Law model predicts a velocity profile that remains parabolic for the entire time range analyzed, while the Newtonian model captures vorticities. © 2022 Trans Tech Publications Ltd, Switzerland.

关键词： Constructal Design Coronary Artery Bypass Newtonian Model Power Law Model Pulsatile Flow

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Cr-modified CuAlBe shape memory alloy: Role of microstructure, thermodynamic parameters, superelasticity, dissipated energy and corrosion resistance

Journal of Alloys and Metallurgical Systems

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Journal of Alloys and Metallurgical Systems 2024年 7卷

作者： Silva, David D.S. Candido, Gemierson V.M. Alves, Ricardo F. Dias, Elisabeth A.M.G.S. Oliveira, Danniel F. Federal University of São Carlos Graduate Program in Materials Science and Engineering SP São Carlos13565-905 Brazil Colorado School of Mines George S. Ansell Department of Metallurgical and Materials Engineering GoldenCO80401 United States Federal University of Paraíba Graduate Program in Mechanical Engineering PB João Pessoa58051-900 Brazil Federal University of Rio Grande do Norte Graduate Program in Materials Science and Engineering RN Natal59078-970 Brazil Federal University of Paraíba Graduate Program in Materials Science and Engineering PB João Pessoa58051-900 Brazil

This study reports the effects of Cr addition on the microstructure, superelasticity and corrosion resistance improvement of CuAlBe shape memory alloy. Analysis via structural, morphological, thermal, mechanical and electrochemical characterizations were performed. The analyses revealed austenite as the stable phase at room temperature for all samples. The increase in the Cr content caused a slight increase in the recovery rate and dissipated energy. Electrochemical results demonstrate that a small addition of Cr (0.1–0.3 wt%) increase the corrosion resistance due the decreases of the corrosion current density and increase of the corrosion potential. © 2024 The Authors

关键词： Corrosion resistance

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DEVELOPING A DIGITAL TWIN FOR SINGLE-CELL mechanical PHENOTYPING MICROFLUIDIC DEVICES 26

DEVELOPING A DIGITAL TWIN FOR SINGLE-CELL MECHANICAL PHENOTY...

引用

26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022

作者： Roychowdhury, Sayan Mahmud, Samreen T. Puleri, Daniel F. Lai, Andre Rex, Rachel Li, Brian Sohn, Lydia L. Randles, Amanda Department of Biomedical Engineering Duke University United States UC Berkeley-UC San Francisco Graduate Program in Bioengineering University of California Berkeley United States Department of Mechanical Engineering University of California Berkeley United States

ISBN: (纸本)9781733419048

Microfluidics can be used to characterize individual cells in a population based on their mechanical traits. In this work, we digitally replicate the microfluidic device developed by Li et al. [1] and perform simulations of a representative AP-1060 cell. We show that the numerical model is able to recover whole-cell deformability index, a metric used to quantify the resistance of cells to compressive deformation, within 3% of the experimental average. These results pave the way for future studies which utilize experimental and computational approaches to optimize geometric design parameters, complement signal analysis, and enhance the acquisition of mechanical information. © 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.

关键词： Fluid structure interaction

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An Online Application of Edge-Cloud Computing for Lithium-Ion Battery with SOC Estimation

An Online Application of Edge-Cloud Computing for Lithium-Io...

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IEEE Conference on Vehicle Power and Propulsion (VPPC)

作者： Joelton Deonei Gotz João Pedro dos Reis Mendes José Rodolfo Galvão Emilson Ribeiro Viana Fernanda Cristina Corrêa Milton Borsato Graduate Program in Mechanical Engineering (PPGEM) Federal Technological University of Paraná Curitiba-PR Brazil Graduate Program in Electrical Engineering (PPGEE) Federal Technological University of Paraná Ponta Grossa-PR Brazil Graduate Program in Physics and Astronomy (PPGFA) Federal Technological University of Paraná Curitiba-PR Brazil

The adoption of cloud and edge computing for several application motivates the monitoring and controlling a Lithium-ion batteries (LIB) online and remotely. In these scenarios, this work presents a case of study by the application of a hybrid concept of edge-cloud computing. The edge collects the data from the cells and sent directly to the cloud where several Machine Learning algorithms can be built, trained and tested. Then, the trained models are downloaded to the edge and do inferences in real time. The proposed idea presented still an SOC estimator based on Long Short-Term Memory (LSTM) with average error below 5%.

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Industrial energy efficiency assessment and prioritization model: An approach based on multi-criteria method PROMETHEE

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International Journal of Sustainable Energy Planning and Management 2023年 37卷 41-60页

作者： Richter, Bernardo Keller Marcondes, Gabriela Hansen Monteiro, Nathalia Juca da Costa, Sergio Eduardo Gouvea Loures, Eduardo R. Deschamps, Fernando de Lima, Edson Pinheiro Industrial and Systems Engineering Graduate Program Pontifical Catholic University of Parana Rua Imaculada Conceição 1155 Curitiba80215-901 Brazil Department of Engineering State University of Pará Travessa Dr. Enéas Pinheiro 2626 Belém66095-015 Brazil Federal University of Technology-Parana Via do Conhecimento Pato Branco85503-390 Brazil Mechanical Engineering Department Federal University of Parana Rua XV de Novembro 1299 Curitiba80060–000 Brazil

In today’s scenario of increasing energy prices, new legislations, and rising consumer concerns regarding environmental issues, industries face an unprecedented challenge of reducing their energy consumption without negatively impacting their profit and productivity. Based on this, companies are focusing on analyzing their energy efficiency, which has various criteria to be considered, and at least three organizational levels. To close this gap, this study developed an industrial energy efficiency assessment and prioritization model based on energy assessment literature. It utilized multi-criteria analysis for the prioritization of industrial energy efficiency measures. To achieve the goal, a literature review was conducted to map relevant energy efficiency practices from which an industrial energy efficiency assessment tool was developed through the lens of three organizational levels (plant, process, and machine). Subsequently, an energy-efficiency project prioritization tool was proposed using the multi-criteria PROMETHEE II method. The assessment and prioritization model was applied to an energy industry for refinement. It generated an overview of the company’s energy efficiency maturity and a ranking of the most recommended measures for the optimal use of energy resources according to established criteria and their weights. Four subcategories (lighting, HVAC systems, compressed air, and motors) were analyzed for the organizational levels, and lighting presented the higher result of a maturity of 2.77 on a scale from 0 to 3, also the maturity of the company was 2.01, which means that is still space for improvement. The improvements were highlighted according to each subcategory studied, pointing to actions that needed to be developed to improve energy efficiency. © 2023, Aalborg University press. All rights reserved.

关键词： Energy efficiency

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Black ice danger area estimation and active speed control research by utilizing road condition sensor

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Journal of Institute of Control, Robotics and Systems 2021年第11期27卷 815-823页

作者： Hwang, Daekyu Kim, Bongsang Lee, Kyuho Sim, Hongseok Moon, Heechang Industrial Convergence Interdepartmental Program Autonomous Vehicle･Intelligent Robotics The Graduate School of Hongik University Korea Republic of Mechanical & System Design Engineering Hongik University Korea Republic of

This study was performed to verify the feasibility of using a black ice danger area estimation function based on the wetness data acquired by a piezoelectric based RCS (Road Condition Sensor) through real road tests under each environment and real vehicle conditions. The techniques and system implementation are considered for the prevention of accidents caused by black ice, which primarily causes critical issues in winter every year. System detects the value of wetness on the road during (or right after) rain and snow using an RCS then can estimate the possibility of the presence of black ice on the forward path at low temperatures by combining with those obtained using the ambient temperature sensor and GIS (GPS and map). Accident avoidance and damage minimization effect is expected by securing safe driving conditions through active speed control. © ICROS 2021.

关键词： Ice

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Pose Synchronization for Semi-Autonomous Dynamic Robotic Swarms with a Passivity-Short Human Operator

Pose Synchronization for Semi-Autonomous Dynamic Robotic Swa...

引用

Annual Conference of Industrial Electronics Society

作者： Reo Kanazawa Toshiyuki Murao Hiroyuki Kawai Graduate Program in Mechanical Engineering Kanazawa Institute of Technology Ishikawa Japan Department of Robotics Kanazawa Institute of Technology Ishikawa Japan

This paper presents a pose synchronization method for semi-autonomous dynamic robotic swarms with a passivityshort human operator. In the human-robot network, a human operator sends a command signal to and receives visual information from only a part of the robotic group. In this setting, the proposed dynamic control scheme achieves not only pose synchronization of all mobile robots but also convergence to the reference pose that the human operator specifies. The main advantage of the proposed method is to guarantee convergence of not only the position but also the orientation to the reference ones in the human-robot network. Finally, we provide human-in-the-loop simulation results through the human operation using a tablet PC to illustrate the performance of the proposed control method.

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Label-Free Classification of L-Histidine Vs Artificial Human Sweat Using Laser Scribed Electrodes and a Multi-Layer Perceptron Neural Network

Label-Free Classification of L-Histidine Vs Artificial Human...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： William García-Rodríguez Andrés Saavedra-Ruiz Pedro J. Resto-Irizarry Department of Mechanical Engineering University of Puerto Rico Mayagüez PR USA Bioengineering Graduate Program University of Puerto Rico Mayagüez PR USA

ISBN: (数字)9798350371499

ISBN: (纸本)9798350371505

A challenge in wearable technology lies in the realtime monitoring of molecular biomarkers associated with human health. Electrochemical sensors are one of the most useful tools for this purpose and are commonly used in health monitoring devices. Electrochemical biosensing is particularly convenient when used in user-friendly, low-cost devices for testing noninvasive body fluids such as sweat and saliva. However, achieving high selectivity and specificity in measurements depends on the complexity of the biomarker and the stability of the biomarker capture molecule. In this study, laser-scribed electrodes (LSEs) were manufactured using a CO2 laser cutter on Polyimide for the label-free classification of sweat components. Cyclic voltammetry experiments were performed on artificial human sweat and the sweat component L-Histidine. The resulting voltammogram data served as input to train a Multi-Layer Perceptron Neural Network (MLP-NN) algorithm capable of classifying L-Histidine and artificial sweat.

关键词： Electrodes Neural networks Measurement by laser beam Polyimides Laser stability Sensors Molecular biomarkers Laser beam cutting Monitoring Testing

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