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Potential anti-biofilm producing marine actinomycetes isolated from sea sediments in Thailand

Agriculture and natural resources 2018年第3期52卷 228-233页

作者： Leetanasaksakul, Kantinan Thamchaipenet, Arinthip Department of Genetics Faculty of Science Kasetsart University Bangkok 10900 Thailand Interdisciplinary Graduate Program in Genetic Engineering Graduate School Kasetsart University Bangkok 10900 Thailand Center for Advanced Studies in Tropical Natural Resources Kasetsart University Bangkok 10900 Thailand

Marine actinomycetes are well known as novel resources of bioactive compounds including anti-biofilm agents with various therapeutic applications. In this study, one hundred and one marine actinomycetes were isolated from sea sediments collected from Andaman sea and the Gulf of Thailand. Morphological study and partial 16S rDNA sequence analysis revealed that most of isolates belong to genus Streptomyces (n = 90, 89.11%) and the rest are rare actinomycetes (n = 11, 10.89%) including Actinopolymorpha, Actinomycetospora, Dietzia Nocardiopsis, Micromonospora and Mycobacterium. Among them, ten and thirteen strains significantly reduced more than 60% of biofilm formation of Escherichia coli and Staphylococcus aureus, respectively. But no such activity was found against Pseudomonas aeruginosa. Further analysis of their supernatants indicated that most of marine actinomycetes secreted non-toxic anti-biofilm agents and some accompanied with protease activity. These are preferred characteristics of anti-biofilm substances that potentially restricted biofilm forming of E. coli and S. aureus and simultaneously prevented bacteria to develop resistance. © 2018 Kasetsart University

关键词： Anti-biofilm Marine actinomycetes

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Ten decadal advances in fungal biology leading towards human well‑being

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Fungal Diversity 2022年第5期116卷 547-614页

作者： Ausana Mapook·Kevin DHyde Kevin D.Hyde Khadija Hassan Blondelle Matio Kemkuignou Adela Cmokova Frank Surup Eric Kuhnert Pathompong Paomephan Tian Cheng Sybren de Hoog Yinggai Song Ruvishika S.Jayawardena Abdullah M.S.Al‑Hatmi Tokameh Mahmoudi Nadia Ponts Lena Studt‑Reinhold Florence Richard‑Forget K.W.Thilini Chethana Dulanjalee L.Harishchandra Peter E.Mortimer Huili Li Saisamorm Lumyong Worawoot Aiduang Jaturong Kumla Nakarin Suwannarach Chitrabhanu S.Bhunjun Feng‑Ming Yu Qi Zhao Doug Schaefer Marc Stadler Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Department Microbial Drugs Helmholtz Centre for Infection Research(HZI)and German Centre for Infection Research(DZIF)Partner Site Hannover‑BraunschweigInhoffenstrasse 738124 BrunswickGermany Institute of Microbiology Technische Universitat BraunschweigSpielmannstrase 738106 BrunswickGermany Laboratory of Fungal Genetics and Metabolism Institute of MicrobiologyCzech Academy of SciencesPragueCzech Republic Centre of Biomolecular Drug Research(BMWZ) Institute for Organic ChemistryLeibniz University HannoverSchneiderberg 3830167 HannoverGermany Department of Biotechnology Faculty of ScienceMahidol University272 Rama VI RoadRatchathewiBangkok 10400Thailand Center of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina HospitalNijmegenThe Netherlands Key Laboratory of Environmental Pollution Monitoring and Disease Control Guizhou Medical UniversityGuiyangChina Microbiology Parasitology and Pathology Graduate ProgramFederal University of ParanaCuritibaBrazil Department of Dermatology Peking University First HospitalPeking UniversityBeijingChina Natural and Medical Sciences Research Center University of NizwaNizwaOman Department of Biochemistry Erasmus University Medical CenterRotterdamThe Netherlands INRAE UR1264 Mycology and Food Safety(MycSA)33882 Villenave d’OrnonFrance Department of Applied Genetics and Cell Biology Institute of Microbial GeneticsUniversity of Natural Resources and Life SciencesVienna(BOKU)Tulln an der DonauAustria Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China Institute of Plant ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Centre for Mountai

Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human *** the current paper,we highlight some important discoveries and developments in applied mycology and interdisciplinary Life Science *** examples concern recently introduced drugs for the treatment of infections and neurological diseases;application of–OMICS techniques and genetic tools in medical mycology and the regulation of mycotoxin production;as well as some highlights of mushroom cultivaton in *** for new diagnostic tools in medical mycology and the exploitation of new candidates for therapeutic drugs,are also *** addition,two entries illustrating the latest developments in the use of fungi for biodegradation and fungal biomaterial production are *** other areas where there have been and/or will be significant developments are also *** is our hope that this paper will help realise the importance of fungi as a potential industrial resource and see the next two decades bring forward many new fungal and fungus-derived products.

关键词： Biomaterial CRISPR Drug development Morel cultivation Mushroom cultivation Mycotoxin biosynthesis Plastic degradation

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Unequal access to social, environmental and health amenities in US urban parks

Nature Cities

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Nature Cities 2024年 861-870页

作者： Richelle L. Winkler Jeffrey A. G. Clark Dexter H. Locke Peleg Kremer Myla F. J. Aronson Fushcia-Ann Hoover Hogyeum Evan Joo Daniele La Rosa KangJae Jerry Lee Susannah B. Lerman Hamil Pearsall Timothy L. V. Vargo Charles H. Nilon Christopher A. Lepczyk United States Department of Agriculture Economic Research Service Kansas City MO USA Natural Areas Conservancy New York NY USA USDA Forest Service Northern Research Station Baltimore MD USA Department of Geography and the Environment Villanova University Villanova PA USA Department of Ecology Evolution and Natural Resources Rutgers The State University of New Jersey New Brunswick NJ USA Department of Earth Environmental and Geographical Sciences University of North Carolina at Charlotte Charlotte NC USA Graduate Program in Ecology and Evolution Rutgers The State University of New Jersey New Brunswick NJ USA Department of Civil Engineering and Architecture University of Catania Catania Italy Department of Parks Recreation and Tourism University of Utah Salt Lake City UT USA USDA Forest Service Northern Research Station Amherst MA USA Department of Geography and Urban Studies Temple University Philadelphia PA USA Urban Ecology Center Milwaukee WI USA School of Natural Resources University of Missouri Columbia MO USA College of Forestry Wildlife and Environment Auburn University Auburn AL USA

Urban parks provide vital social, environmental and health benefits to residents. However, the spatial distribution of parks, and the amenities they provide, may not be equitably distributed within cities. We examine the accessibility of urban parks with different social, environmental and health amenities by race and ethnicity. We identified 122,988 urban parks across the USA, measured the racial/ethnic population distribution within a 10-min walkshed around each park and compared these distributions to the overall demographics of the city. We found that the spatial distribution of parks as well as park amenities differ according to the neighborhood demographics. Racial/ethnic compositions of neighborhoods surrounding parks tend to be whiter than other parts of the same cities, though there are regional differences. Parks in predominantly white neighborhoods are cooler in the summer and have more tree cover compared with parks in neighborhoods with greater proportions of Hispanic and Black residents. Differences in amenities hold across regions of the country. Our study demonstrates that inequities in access to high-quality parks are widespread across the USA.

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Enhancing the sustainability and effectiveness of non-governmental organizations: An integrated neutrosophic decision-making model for determining the most effective corporate governance strategies

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engineering Applications of Artificial Intelligence 2025年 156卷

作者： Emrah Ayhan Hakan Gökhan Gündoğdu Ahmet Aytekin Ahmet Furkan Karakaya Vladimir Simic Dragan Pamucar Department of Political Science and Public Administration Faculty of Economics and Administrative Sciences Anadolu University Tepebaşı 26470 Eskişehir Türkiye Department of Business Administration Hopa Faculty of Economics and Administrative Sciences Artvin Çoruh University Hopa 08100 Artvin Türkiye Public Administration Master Program Graduate Education Institute Anadolu University Tepebaşı 26470 Eskişehir Türkiye University of Belgrade Faculty of Transport and Traffic Engineering Vojvode Stepe 305 11010 Belgrade Serbia Yuan Ze University College of Engineering Department of Industrial Engineering and Management Taoyuan City 320315 Taiwan Department of Computer Science and Engineering College of Informatics Korea University 145 Anam-ro Seongbuk-gu Seoul 02841 Republic of Korea Department of Operations Research and Statistics Faculty of Organizational Sciences University of Belgrade Belgrade Serbia Department of Mechanics and Mathematics Western Caspian University Baku Azerbaijan İstinye University Faculty of Engineering and Natural Sciences Industrial Engineering Department Sarıyer 34396 İstanbul Türkiye

This research explores the development of effective corporate governance strategies for non-governmental organizations (NGOs) by evaluating both critical decision criteria and innovative organizational models. Based on an extensive literature review, seven governance criteria were identified: credibility and non-profit orientation, regular information flow and transparency, level of institutionalization, frequency of leadership turnover, internal and external stakeholder relations, annual budget, and ideological or religious motivation. In addition, five innovative organizational models were selected as strategic alternatives: continuous learning organization, technology-oriented policy development, income diversification, pluralistic governance, and transformational leadership. The empirical data were gathered through interviews with 16 experts from academia, civil society, and public institutions in Türkiye. To address the complexity and uncertainty of decision-making processes, a hybrid type-2 neutrosophic number (T2NN) multi-criteria decision-making methodology is introduced. The T2NN-ranking comparison and T2NN-criteria importance through intercriteria correlation methods are used to determine the weight of criteria, while T2NN-stable preference ordering towards ideal solution is utilized to rank the alternative models. Results show that the level of institutionalization is the most significant criterion, and income diversification is the most effective organizational model for improving NGO sustainability. The study not only provides practical guidance for NGO leaders but also introduces a robust methodological approach applicable to governance challenges under uncertain conditions.

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Correction: Optimized framework for evaluating F3 transgressive segregants in cayenne pepper

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BMC plant biology 2025年第1期25卷 300页

作者： Ifayanti Ridwan Muh Farid Feranita Haring Nuniek Widiayani Ahmad Yani Nirwansyah Amier Muhammad Alfan Ikhlasul Amal Jekvy Hendra Nawab Ali Mekhled M Alenazi Mahmoud F Seleiman Willy Bayuardi Suwarno Muhammad Fuad Anshori Department of Agronomy Faculty of Agriculture Hasanuddin University Makassar 90245 Indonesia. Agrotechnology Bachelor Study Program Faculty of Agriculture Hasanuddin University Makassar 90245 Indonesia. Agrotechnology Master Study Program Faculty of Agriculture Hasanuddin University Makassar 90245 Indonesia. Agricultural Science Doctoral Program Graduate School Hasanuddin University Makassar 90245 Indonesia. Directorate of Horticultural Protection Agricultural Ministry Jakarta 12520 Indonesia. Department of Biosystems and Agricultural Engineering (BAE) College of Agriculture and Natural Resources Michigan State University East Lansing USA. Department of Plant Production College of Food and Agriculture Sciences King Saud University Riyadh Saudi Arabia. Department of Agronomy and Horticulture Faculty of Agriculture IPB University Bogor 11680 Indonesia. Department of Agronomy Faculty of Agriculture Hasanuddin University Makassar 90245 Indonesia. fuad.anshori@unhas.ac.id.

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Sustainable improvement of food SMEs through halal certification: A meta-analysis

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AIP Conference Proceedings 2024年第1期2957卷

作者： Rizal Bahara Muhammad N. Aidi Khaswar Syamsu Euis Sunarti Anuraga Jayanegara Natural Resources and Environmental Management Science Study Program Graduate School IPB University Jl Pajajaran No 1 Kampus IPB Baranangsiang Bogor West Java 1614 Indonesia Statistics and Data Science Department Mathematics and Natural Science Faculty IPB University Jl. Lingkar Kampus IPB Dramaga Bogor West Java 16680 Indonesia Halal Science Center LPPM IPB. Gedung Pascasarjana Gedung Kimia IPB University Jl Pajajaran No 1 Kampus IPB Baranangsiang Bogor West Java 1644 Indonesia Department of Family and Consumer Sciences Faculty of Human Ecology IPB University Jl. Lingkar Kampus IPB Dramaga Bogor West Java 16610 Indonesia Department of Nutrition and Feed Technology Faculty of Animal Science IPB University Jl. Lingkar Kampus IPB Dramaga Bogor West Java 16680 Indonesia

Small and medium enterprises (SMEs) are one of the important economic drivers in Indonesia, including during the Covid-19 pandemic. Indonesia as the country with the largest Muslim population requires halal certificates for all food products sold in Indonesia. Obstacles to the implementation and certification of halal in the food SME sector are still encountered due to, among others, the cost of certification, knowledge from human resources, ease of access and information. The purpose of this study was to evaluate the role of halal certification on financial performance in Food SMEs by employing the meta-analysis method. A number of six articles out of 55 articles were selected and integrated into a database. The data were analyzed based on the Hedges’ d (standardized mean difference/SMD) effect size values and confidence interval (CI) values by using the Open MEE software. The results showed that halal-certified food SMEs significantly increased sales (SMD: 3.182; 95% CI:1.228 to 5.136; p<0.001) as compared to those of food SMEs that were not halal-certified. In the location in the Indonesia subgroup, halal certification at Food SMEs in Bogor city had a higher sale (SMD: 12.105; 95% CI: 10.289 to 13.922; p<0.001) compared to other cities. The conclusion of this study is that halal certification enhances sales and thus contributes to the sustainability of food SMEs.

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Role of Lactobacillus sakei strain pro7 to reduce dichloro diphenyl trichloroethane level 1

Role of Lactobacillus sakei strain pro7 to reduce dichloro d...

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1st SEMIRATA-International Conference on Science and Technology, SEMIRATA-ICST 2018

作者： Nasution, L. Bakti, D. Agusnar, H. Harahap, E.M. Post Graduate of Natural Resources and Environment Management Program School of Post-Graduate University of Sumatera Utara Indonesia Department of Agrotechnology Faculty of Agriculture University of Sumatera Utara Indonesia Department of Chemistry Faculty of Mathematics and Natural Sciences University of Sumatera Utara Indonesia Department of Soil Science Faculty of Agriculture University of Sumatera Utara Indonesia

Several species of bacteria can be utilized to degrade the residual insecticides. One of them was chosen from the genus Lactobacillus. The purposes of soils in Merdeka Village, Karo Regency, North Sumatra, Indonesia as well as to investigate bacteria which is capable of surviving in DDT-contaminated soil. Method for the residual analysis of the soil utilizes Quechers tube, and the bacterial propagation were performed in the medium mineral 4 (MM4). Purification to bacterial isolates was carried out in the Plate Count Agar (PCA) medium and subsequently followed by morphological identification. The results of this study show that the soil were contaminated by O'P'-DDT ranging from 2.2 μgKg-1 to 9.0 μgKg-1. Phylogenetic analysis proves that the Lactobacillus sakei Strain PRO7 bacteria was identified. The growth rate of DDT biodegradation by Lactobacillus sakei Strain PRO7 bacteria is noted the highest at 7.89 observation and reaches 95.1% of biodegradation percentage at the 20 ppm DDT concentration. © Published under licence by IOP Publishing Ltd.

关键词： Bacteria

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Analysis of Lead (Pb) and Zinc (Zn) Content in Sediments and Faunus ater at Bale Lhoknga Aceh Besar District 1

Analysis of Lead (Pb) and Zinc (Zn) Content in Sediments and...

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1st International Conference on Education, Science and Technology, ICON-EST 2018

作者： Agustina, Rahmi Sarong, M. Ali Yulianda, Fredinan Suhendrayatna Rahmadi Lelifajri Graduate School of Mathematics and Applied Sciences Syiah Kuala University Banda Aceh23111 Indonesia Departement of Biology Faculty of Teacher Training and Education Jabal Ghafur University Sigli24171 Indonesia Departement of Biology Faculty of Teacher Training and Education Syiah Kuala University Banda Aceh23111 Indonesia Departement of Water Resources Management Faculty of Fisheries and Marine Sciences Bogor Agricultural University Bogor16680 Indonesia Department of Chemical Engineering Faculty of Engineering Syiah Kuala University Banda Aceh23111 Indonesia Department of Chemistry Faculty of Mathematics and Science Post Graduate Program Syiah Kuala University Banda Aceh23111 Indonesia Department of Chemistry Faculty of Mathematics and Sci. Post Graduate Program Syiah Kuala Univ. Banda Aceh23111 Indonesia

Faunus ater is a favoritemollusca that is often found on the Bale River. Local people use these snails as food for consumption along with their main food. Bale River itself is located adjacent to the cement factory, used water washing machines distributed to the river is feared to support the presence of lead (Pb) and zinc (Zn) metals in the river. This study aims to analyze the relationship of Pb and Zn content in sediments to the content of Pb and Zn in Faunus ater. Data collection was carried out in Februari until April 2018. The relationship between Pb and Zn content in sediments with Pb and Zn content in the body of Faunus ater was analyzed by correlation analysis. The results of the data analysis showed that the metal content of Pb and Zn in sediment and Faunus aterwere found to vary. The highest Pb content in sediment was found at station 2 in March, amounting to 32.87 mg / kg. while the highest Zn content was found at station 1 in March amounting to 84 mg / kg. The relationship of heavy metals Pb and Zn in sediments to the content of Pb and Zn in the body of Faunus ater showed a negative correlation. The conclusion of this study is that there is no correlation between the content of Pb and Zn heavy metals in sediments on the content of lead Pb and Zn in the body of Faunus ater at the Bale Lhoknga River in Aceh Besar District. © Published under licence by IOP Publishing Ltd.

关键词： Rivers

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Classes and phyla of the kingdom Fungi

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Fungal Diversity 2024年第1期124卷 1-165页

作者： Nalin N.Wijayawardene Kevin D.Hyde Kirill V.Mikhailov Gabor Peter Andre Aptroot Carmen L.A.Pires‑Zottarelli Bruno T.Goto Yuri S.Tokarev Danny Haelewaters Samantha C.Karunarathna Paul M.Kirk Andre L.C.M.de A.Santiago Ramesh K.Saxena Nathan Schoutteten Madhara K.Wimalasena Vladimir V.Aleoshin Abdullah M.S.Al‑Hatmi Kahandawa G.S.U.Ariyawansa Amanda R.Assuncao Thushara C.Bamunuarachchige Hans‑Otto Baral D.Jayarama Bhat Janusz Błaszkowski Teun Boekhout Nattawut Boonyuen Michael Brysch‑Herzberg Bin Cao Jonathan Cazabonne Xue‑Mei Chen Claudia Coleine Dong‑Qin Dai Heide‑Marie Daniel Suzana B.G.da Silva Francisco Adriano de Souza Somayeh Dolatabadi Manish K.Dubey Arun K.Dutta Aseni Ediriweera Eleonora Egidi Mostafa S.Elshahed Xinlei Fan Juliana R.B.Felix Mahesh C.A.Galappaththi Marizeth Groenewald Li‑Su Han Bo Huang Vedprakash G.Hurdeal Anastasia N.Ignatieva Gustavo H.Jeronimo Ana L.de Jesus Serhii Kondratyuk Jaturong Kumla Martin Kukwa Qirui Li Juliana L.R.Lima Xiao‑Yong Liu Wenhua Lu H.Thorsten Lumbsch Hugo Madrid Franco Magurno Guy Marson Eric H.C.McKenzie Audrius Menkis Armin Mešić Elaine C.R.Nascimento Elena S.Nassonova Yong Nie Naasson V.L.Oliveira Emilia A.Ossowska Julia Pawłowska Ursula Peintner Igor R.Pozdnyakov Bhagya M.Premarathne A.K.Hasith Priyashantha C.Alisha Quandt Mariana B.Queiroz Kunhiraman C.Rajeshkumar Mubashar Raza Niranjan Roy Milan C.Samarakoon Alessandra A.Santos Lidiane A.Santos Felix Schumm Laura Selbmann Faruk Selcuk D.Rabern Simmons Anastasia V.Simakova Maudy Th.Smith Onden Paraparath Sruthi Nakarin Suwannarach Kazuaki Tanaka Saowaluck Tibpromma Elias O.Tomas Merve Ulukapı Nicolas Van Vooren Dhanushka N.Wanasinghe Evi Weber Qianzhen Wu Er Fu Yang Ryuichi Yoshioka Noha H.Youssef Annemarie Zandijk Gui‑Qing Zhang Jin‑Yong Zhang Heng Zhao RuiLin Zhao Oleg A.Zverkov Marco Thines Sergey A.Karpov Center for Yunnan Plateau Biological Resources Protection and Utilization College of Biological Resource and Food EngineeringQujing Normal UniversityQujing 655011YunnanPeople’s Republic of China Tropical Microbiology Research Foundation 96/N/10Meemanagoda RoadPannipitiya 10230Sri Lanka Department of Bioprocess Technology Faculty of TechnologyRajarata UniversityMihintaleSri Lanka Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiangRai 57100Thailand Innovative Institutefor Plant Health Zhongkai University of Agriculture and EngineeringGuangzhou 510225People’s Republic of China CAS Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunmingYunnanChina Belozersky Institute of Physicochemical Biology Lomonosov Moscow State UniversityLeninskye Gory1Build.40Moscow 119991Russian Federation Kharkevich Institute for Information Transmission Problems Russian Academy of SciencesMoscow 127051Russian Federation National Collection of Agricultural and Industrial Microorganisms Institute of Food Science and TechnologyHungarian University of Agriculture and Life SciencesSomlóiút 14‑161118 BudapestHungary Instituto de Biociências Universidade Federal de Mato Grosso do SulAvenida Costa e Silvas/n Bairro UniversitárioCampo GrandeMS CEP 79070‑900Brazil Instituto de Pesquisas Ambientais Secretaria do Meio AmbienteInfraestrutura e LogísticaAv.Miguel Stéfano 3687São PauloSP CEP 04301‑902Brazil Departamento de Botânica e Zoologia Universidade Federal do Rio Grande do NorteCampus UniversitárioNatalRN 59078-900Brazil All-Russian Institute of Plant Protection Sh.Podbelskogo 3PushkinSt.Petersburg 196608Russia Research Group Mycology Department of BiologyGhent University9000 GhentBelgium Faculty of Science University of South Bohemia37005ČeskéBudějoviceCzech Republic Department of Ecology and Evolutionary Biology University of Colora

Fungi are one of the most diverse groups of organisms with an estimated number of species in the range of 2–3 *** higher-level ranking of fungi has been discussed in the framework of molecular phylogenetics since Hibbett et al.,and the definition and the higher ranks(e.g.,phyla)of the‘true fungi’have been revised in several subsequent *** accumulation of novel genomic data and the advancements in phylogenetics now facilitate a robust and precise foundation for the higher-level classification within the *** study provides an updated classification of the kingdom Fungi,drawing upon a comprehensive phylogenomic analysis of Holomycota,with which we outline well-supported nodes of the fungal tree and explore more contentious *** accept 19 phyla of Fungi,***,Ascomycota,Basidiobolomycota,Basidiomycota,Blastocladiomycota,Calcarisporiellomycota,Chytridiomycota,Entomophthoromycota,Entorrhizomycota,Glomeromycota,Kickxellomycota,Monoblepharomycota,Mortierellomycota,Mucoromycota,Neocallimastigomycota,Olpidiomycota,Rozellomycota,Sanchytriomycota,and *** the phylogenies,Caulochytriomycota resides in Chytridiomycota;thus,the former is regarded as a synonym of the latter,while Caulochytriomycetes is viewed as a class in *** provide a description of each phylum followed by its classes.A new subphylum,Sanchytriomycotina Karpov is introduced as the only subphylum in *** subclass Pneumocystomycetidae Kirk et *** Pneumocystomycetes,Ascomycota is invalid and thus *** of fossil fungi in phyla and classes are also discussed,providing examples.

关键词： Caulochytriomycota Phylogenomic analyses Pneumocystomycetidae Sanchytriomycotina

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Medical waste water management in Bhayangkara General Hospital at Medan city towards green hospital concept

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IOP Conference Series: Earth and Environmental Science 2019年第1期348卷

作者： R Tampubolon R H Harahap E S M Nababan Graduate Student of Magister Program of Environmental and Natural Resources Management North Sumatera University Lecture of Graduate School of Environmental and Natural Resources Management North Sumatera University

Bhayangkara General Hospital is one of the hospitals in Medan City, which is located in the official residential area of the Mobile Brigade personnels of the Sumatera Utara Regional Police, therefore this Hospital is considered feasible to be used as a research location to see how the handling of medical waste water is managed properly. This type of research is a mixed method between qualitative and quantitative research. The purpose of this research was to determine the handling of medical waste water management at the Bhayangkara General Hospital Medan towards the Green Hospital development program. The green hospital concept is a PROFER criteria, one of the indicators is from the aspect of waste management (KLHK). Respondents in this research amounted to 40 people who were taken purposely (purposive sampling). Data were analyzed using CFA (Confirmatory Factor Analysis). Based on the processed data through CFA, an analysis of several related variables was obtained, namely; the variable of liquid waste (Y) Measurement indicators of physical and chemical parameters (1.00 coefficient); treatment of waste water management installation (0.2 coefficient); Monitoring of waste water management installation (0.2 coefficient); Utilization of final Results of waste water management installation from the water waste (0.9 coefficient).

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