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Assessing the Dietary Probabilistic Risk from Inorganic Arsenic and Benefits from Indispensable Amino Acids in the Meat from Chickens Provided Seaweed-Supplemented Feeds in the Diet of the Taiwanese Population

SSRN

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SSRN 2022年

作者： Hung, Ching-Chi Lin, Hsin-Tang Chen, Ching-Yi Jung, Chien-Cheng Ni, Shih-Pei Chen, Kuan-Yi Chang, Chia-Chin Lee, Tsung-Yu Chiang, Chow-Feng Livestock Research Institute Council of Agriculture Executive Yuan. No. 112 Muchang Xinhua Dist Tainan City71246 Taiwan Graduate Institute of Food Safety National Chung Hsing University No. 145 Xingda Rd. South Dist Taichung City40227 Taiwan Department of Animal Science and Technology National Taiwan University No. 50 Lane 155 Sec 3 Keelung Rd Taipei City10672 Taiwan Department of Public Health China Medical University No. 100 Sec. 1 Jingmao Rd. Beitun Dist Taichung City406040 Taiwan Master Program for Food and Drug Safety China Medical University No. 100 Sec. 1 Jingmao Rd. Beitun Dist Taichung City406040 Taiwan

Seaweed is a common nutritional supplement in animal feed, but it may be a source of arsenic (As) contamination. As-contaminated commercial seaweed additives from Sargassum hemiphyllum var. chinense (SHC) and Ulva lactuca (UL) were evaluated. Tests involving feed containing 2% and 5% SHC (10,847 µg/kg total As (tAs)) and UL (115 µg/kg tAs) were conducted. After chickens were reared for 35 days, breast meat samples were taken and analyzed to assess eight indispensable amino acids (AAs) and four As species. Consumption rate (CR) data (n = 3343) were obtained from 24-hour dietary recalls in the 2005–2008 Nutrition and health Surveys in Taiwan (NAHSIT). A Monte Carlo simulation (n = 10,000) was performed to match CR and concentration (C) data for the estimated exposure dose (EDI). Inorganic As (iAs) was 93.6%–96.2% of tAs in feed, while it was 3.9%–34.7% in the chicken breasts. A low biotransfer factor of 0.0062 day/kg was found using transfer and mass balance analyses, which suggest a high degree of methylation and high excretion rate (98.8%). For the 5% SHC test, the mean EDI was 0.0073 µg/kg/day for adult consumers (18+ years old) and 0.013 µg/kg/day for children (1–18 years old). For the 5% SHC test, when the margin of exposure (MOE) risk criteria was 1000, the level of protection for whole-group adults was insufficient at 81% ( © 2022, The Authors. All rights reserved.

关键词： Monte Carlo methods

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Enhancing antioxidant activity of corn bract and silk juices through biotransformation of polyphenols by Lactobacillus paracasei TJ199 fermentation

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Food Chemistry: X 2025年 28卷

作者： Xiaohui Tang Huanyong Lv Hailong Wang Huixin Yang Baogang Zhang Ling Cong Xinyi Li Menghan Ma Yunhe Xu Lili Zhang Liaoning Provincial Professional Technology Innovation Center of Meat Processing and Quality-Safety Control College of Food and Health Jinzhou Medical University Jinzhou 121000 China Liaoning Agricultural Vocational and Technical College Yingkou 115007 China Institute of Scientific and Technological Development Shenyang Agricultural University Shenyang 110161 China Comparative Molecular Biosciences Graduate Program University of Minnesota–Twin Cities St. Paul MN 55108 Paul MN United States College of Pharmacy Jinzhou Medical University Jinzhou 121001 China The Third Affiliated Hospital of Jinzhou Medical University Jinzhou 121001 China

To enhance the bioactivity of corn bract and silk, we isolated Lactobacillus paracasei TJ199 - a strain with exceptional antioxidant capacity - was used to ferment corn bract juice (CBJ) and silk juice (CSJ). Fermentation increased total phenolic (0.47 - and 0.23 - fold) and flavonoid contents in CBJ and CSJ, respectively. Antioxidant activity was significantly enhanced, particularly in DPPH (increased by 0.34 and 0.38 - fold), ABTS (increased by 2.76 and 1.40 - fold) scavenging activity, and FRAP (increased by 3.67 and 2.22 - fold). Widely targeted metabolomics identified 348 phenolic compounds, including butin, curcumin, demethoxycurcumin, they primarily enriched in flavonoid and anthocyanin biosynthesis pathways, and underwent TJ199 - mediated structural modifications (including hydroxylation, deglycosylation, and seven other reactions). Upregulated phenolic products (butin) exhibited stronger antioxidant activity than precursors (liquiritigenin) after biotransformation. These findings provided insights for developing corn bract and silk as food ingredients.

关键词： Corn bract juice Corn silk juice Widely targeted metabolomic analysis Phenolic compounds Antioxidant activity Lactic acid fermentation

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Correction to: Clinical and Immunological Heterogeneity in Japanese Patients with Gain-of-Function Variants in STAT3

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Journal of clinical immunology 2021年第4期41卷 791-794页

作者： Kay Tanita Fumiaki Sakura Ryusuke Nambu Miyuki Tsumura Yusuke Imanaka Hidenori Ohnishi Zenichiro Kato Jie Pan Akihiro Hoshino Koji Suzuki Motoko Yasutomi Shuichiro Umetsu Chizuru Okada Masatoshi Takagi Kohsuke Imai Osamu Ohara Alexo M Muise Satoshi Okada Tomohiro Morio Hirokazu Kanegane Department of Pediatrics and Developmental Biology Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University (TMDU) Tokyo Japan. Department of Pediatrics Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan. Division of Gastroenterology and Hepatology Saitama Children's Medical Center Saitama Japan. SickKids Inflammatory Bowel Disease Center The Hospital for Sick Children Toronto ON Canada. Cell Biology Program Research Institute The Hospital for Sick Children Toronto ON Canada. Department of Pediatrics Gifu University Graduate School of Medicine Gifu Japan. Structural Medicine United Graduate School of Drug Discovery and Medical Information Sciences Gifu University Gifu Japan. Department of Pediatrics Faculty of Medical Sciences University of Fukui Fukui Japan. Department of Pediatric Hepatology and Gastroenterology Saiseikai Yokohama-shi Tobu Hospital Yokohama Kanagawa Japan. Hiroshima Chuodori Children Clinic Hiroshima Japan. Department of Community Pediatrics Perinatal and Maternal Medicine Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University (TMDU) Tokyo Japan. Department of Technology Development Kazusa DNA Research Institute Chiba Japan. Laboratory for Integrative Genomics RIKEN Center for Integrative Medical Sciences Yokohama Japan. Department of Pediatrics Institute of Medical Science and Biochemistry University of Toronto the Hospital for Sick Children Toronto ON Canada. Department of Child Health and Development Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University (TMDU) 1-5-45 Yushima Bunkyo-ku Tokyo 113-8519 Japan. hkanegane.ped@tmd.ac.jp.

A Correction to this paper has been published: https://***/10.1007/s10875-021-01014-6

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Experimental modeling of Alzheimer's disease: Translational lessons from cross-taxon analyses

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Alzheimer's & dementia : the journal of the Alzheimer's Association 2025年第5期21卷 e70273页

作者： Konstantin B Yenkoyan Maria M Kotova Kirill V Apukhtin David S Galstyan Tamara G Amstislavskaya Tatyana Strekalova Murilo S de Abreu Vergine A Chavushyan Lee Wei Lim Longen Yang Denis D Rosemberg Allan V Kalueff Neuroscience Laboratory COBRAIN Center Yerevan State Medical University after M. Heratsi Yerevan Armenia. Neuroscience Program Sirius University of Science and Technology Sochi Russia. Institute of Translational Biomedicine St. Petersburg State University St. Petersburg Russia. Institute of Experimental Medicine Almazov National Medical Research Centre Ministry of Healthcare of Russian Federation St. Petersburg Russia. Scientific Research Institute of Neurosciences and Medicine Novosibirsk Russia. Research Institute of General Pathology and Pathophysiology Moscow Russia. Graduate Program in Health Sciences Federal University of Health Sciences of Porto Alegre Porto Alegre Brazil. Department of Biosciences and Bioinformatics School of Science Xi'an Jiaotong-Liverpool University Suzhou China. Suzhou Municipal Key Laboratory of Neurobiology and Cell Signaling School of Science Xi'an Jiaotong-Liverpool University Suzhou China. Laboratory of Experimental Neuropsychobiology Department of Biochemistry and Molecular Biology Natural and Exact Sciences Center Federal University of Santa Maria Santa Maria Brazil. Graduate Program in Biological Sciences: Toxicological Biochemistry Federal University of Santa Maria Santa Maria Brazil. The International Zebrafish Neuroscience Research Consortium (ZNRC) Slidell Louisiana USA.

Alzheimer's disease (AD) is a severely debilitating neurodegenerative disease with a rapidly increasing global prevalence, poorly understood causes, and no efficient treatments. Experimental models are valuable for studying AD pathogenesis, including amyloid beta and tau accumulation, synaptic dysfunction, and neuroinflammation. While no model fully reproduces the disease, we take an evolutionary biology approach to discuss available models across taxa, from mammals (rodents, primates) to zebrafish, Drosophila melanogaster, and Caenorhabditis elegans. Evaluating their strengths and limitations provides insight into disease mechanisms and may refine research strategies for improved diagnostics and therapeutic screening. Traditional models have significantly contributed to AD research, yet their translational limitations highlight the need for physiologically relevant alternatives. Integrating humanized rodent models, zebrafish, organoids, and induced pluripotent stem cell-based systems-along with advances in bioengineering and genetic editing-may offer a more comprehensive framework to bridge the gap between preclinical research and clinical application. HIGHLIGHTS: Experimental models across rodents, primates, zebrafish, fruit flies, and worms provide key insights into Alzheimer's disease (AD). Cross-taxon comparisons assess strengths and weaknesses in AD models. Evolutionary biology approaches refine experimental strategies for AD research. Diverse animal models improve understanding of AD pathogenesis. Cross-species models enhance diagnostics and therapeutic strategy development.

关键词： Alzheimer's disease animal models cross‐taxon analyses evolutionary psychiatry translation medicine

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Evaluating the antiviral efficacy and specificity of chlorogenic acid and related herbal extracts against SARS-CoV-2 variants via spike protein binding intervention

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Journal of Traditional and Complementary Medicine 2024年

作者： Hsieh, Wen-Yu Yu, Chu-Nien Chen, Chang-Chang Chiou, Chun-Tang Green, Brian D. Lee, Oscar K. Wu, Chia-Chune Doan, Ly Hien Huang, Chi-Ying F. Huang, Cheng Liu, Chien-Ju Chen, Yu-Hsin Cheng, Jing-Jy Pan, Heng-Chih Liu, Hui-Kang Biomedical Industry Ph.D. Program National Yang Ming Chiao Tung University Taipei 11221 Taiwan Institute of Clinical Medicine National Yang Ming Chiao Tung University Taipei 11221 Taiwan Division of Chinese Materia Medica Development National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei 11221 Taiwan Institute for Global Food Security School of Biological Sciences Queen's University Belfast Belfast BT7 1NN United Kingdom Department of Orthopedics China Medical University Hospital Taichung Taiwan Institute of Biopharmaceutical Sciences College of Pharmaceutical Sciences National Yang Ming Chiao Tung University Taipei 11221 Taiwan Institute of Biotechnology Vietnam Academy of Science and Technology Hanoi Viet Nam Program in Molecular Medicine College of Life Sciences National Yang Ming Chiao Tung University Taipei 11221 Taiwan Taiwan National Graduate Program in Molecular Medicine Academia Sinica National Yang Ming Chiao Tung University Taipei 11221 Taiwan Institute of Clinical Medicine College of Medicine National Yang Ming Chiao Tung Taipei 11221 Taiwan Department of Biotechnology and Laboratory Science in Medicine School of Biomedical Science and Engineering National Yang Ming Chiao Tung Taipei 11221 Taiwan Department of Biochemistry School of Medicine Kaohsiung Medical University Kaohsiung 80708 Taiwan Department of Earth and Life Sciences University of Taipei Taipei 11036 Taiwan Tea and Beverage Research Station Ministry of Agriculture Yangmei Township Taoyuan County 326011 Taiwan Taichung District Agricultural Research and Extension Station Ministry of Agriculture Chang-Hwa County 515008 Taiwan Division of Basic Chinese Medicine National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei 11221 Taiwan Department of Nephrology Chang Gung Memorial Hospital Keelung City 204201 Taiwan Ph.D. Program in the Clinical Drug Development of Herbal Medicine Taipei Medical University Taipei

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus infect the respiratory tract through surface proteins, causing similar symptoms. Since the onset of the COVID-19 pandemic, both viruses have posed significant ongoing global health threats. Like the influenza virus, SARS-CoV-2 evolves into variants that can reduce vaccine efficacy. Thus, herbal medicines are being explored as supplementary options to enhance protection against these infections. This study aimed to investigate the therapeutic potential of chlorogenic acid (3-CQA) and related extracts from green coffee beans and Echinacea purpurea against SARS-CoV-2 variants and H1N1 infection. The methods employed included an ELISA-based trimeric spike protein binding assay, viral infection assays, plaque assays, and molecular docking studies. Results showed that 3-CQA blocked spike protein/angiotensin converting enzyme 2 (ACE2) binding for most SARS-CoV-2 variants of concern, except the Delta variant. Extracts from Green coffee bean and E. purpurea effectively blocked all variants tested. Additionally, antibodies blocked spike protein binding up to Omicron BA.2. Molecular docking suggested that 3-CQA binding to Omicron BA.1, BA.2, and BA.4, though not to the Delta spike protein, may lead to steric hindrance, preventing receptor-binding domain interactions with ACE2. Finally, both 3-CQA and E. purpurea extract showed preventive effects against H1N1 viral infection, though with lower potency compared to SARS-CoV-2. In conclusion, 3-CQA has potential as a phytoconstituent marker for herbs with bioactive properties against SARS-CoV-2 and H1N1 viral infections. © 2024 Center for Food and Biomolecules, National Taiwan University

关键词： Chlorogenic acid COVID-19 Echinacea purpurea Green coffee bean H1N1 influenza virus SARS-CoV-2 variants Spike protein

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Uncovering the conformational dynamics of dengue virus and its virus-like particles as novel vaccine candidates

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Biophysical Journal 2023年第3期122卷 508a-509a页

作者： Jan K. Marzinek Venkata Raghuvamsi Palur Gielenny Salem Fan-Chi Chen Shang-Rung Wu Peter J. Bond Day-Yu Chao Bioinformatics Institute Agency for Science Technology and Research Singapore Republic of Singapore Graduate Institute of Microbiology and Public Health College of Veterinary Medicine National Chung Hsing University Taichung City Taiwan Microbial Genomics Ph.D. Program National Chung Hsing University Taichung City Taiwan Academia Sinica Taipei Taiwan Department of Dentistry Institute of Oral Medicine National Cheng Kung University Tainan Taiwan Department of Biological Sciences National University of Singapore Singapore Republic of Singapore

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Performance of joint gamma-ray observations with MAGIC and LST-1 telescopes 38

Performance of joint gamma-ray observations with MAGIC and L...

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38th International Cosmic Ray Conference, ICRC 2023

作者： Di Pierro, F. Berti, A. de Menezes, R. Jobst, E. Ohtani, Y. Sitarek, J. Suda, Y. Visentin, E. Abe, H. Abe, K. Abe, S. Abhir, J. Acciari, V.A. Aguasca-Cabot, A. Agudo, I. Alvarez Crespo, N. Aniello, T. Ansoldi, S. Antonelli, L.A. Aramo, C. Arbet-Engels, A. Cornelia, A. Artero, M. Asano, K. Aubert, P. Baack, D. Babić, A. Baktash, A. Bamba, A. Baquero Larriva, A. Baroncelli, L. Barres de Almeida, U. Barrio, J.A. Batkovic, I. Baxter, J. Becerra González, J. Bednarek, W. Bernardini, E. Bernardos, M.I. Bernete Medrano, J. Besenrieder, J. Bhattacharjee, P. Biederbeck, N. Bigongiari, C. Biland, A. Bissaldi, E. Blanch, O. Bonnoli, G. Bordas, P. Bošnjak, Ž. Bulgarelli, A. Burelli, I. Burmistrov, L. Buscemi, M. Busetto, G. Campoy-Ordaz, A. Cardillo, M. Caroff, S. Carosi, A. Carosi, R. Carrasco, M.S. Carretero-Castrillo, M. Cassol, F. Castro-Tirado, A.J. Cauz, D. Cerasole, D. Ceribella, G. Chai, Y. Cheng, K. Chiavassa, A. Chikawa, M. Chilingarian, A. Chytka, L. Cifuentes, A. Cikota, S. Colombo, E. Contreras, J.L. Cortina, J. Costantini, H. Covino, S. D’Amico, G. Dalchenko, M. D’Elia, V. Da Vela, P. Dazzi, F. De Angelis, A. de Bony de Lavergne, M. De Lotto, B. De Lucia, M. de Menezes, R. Del Peral, L. Deleglise, G. Delfino, M. Delgado, C. Delgado Mengual, J. della Volpe, D. Dellaiera, M. Del Popolo, A. Depaoli, D. Di Piano, A. Di Pierro, F. Di Pilato, A. Di Tria, R. Di Venere, L. Díaz, C. Dominik, R.M. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Eisenberger, L. Elsässer, D. Emery, G. Escudero, J. Fallah Ramazani, V. Fariña, L. Fattorini, A. Ferrara, G. Ferrarotto, F. Fiasson, A. Foffano, L. Font, L. Freixas Coromina, L. Fröse, S. Fukami, S. Fukazawa, Y. Garcia, E. Garcia López, R. Garczarczyk, M. Gasbarra, C. Gasparrini, D. Gasparyan, S. Gaug, M. Geyer, D. Giesbrecht Paiva, J. Giglietto, N. Giordano, F. Gliwny, P. Godinovic, N. Grau, R. Green, J. Green, D. Gunji, S. Günther, P. Hackfeld, J. Hadasch, D. Hahn, A. Hashiyama, K. Hassan, T. Hayashi, K. INFN Torino Via P. Giuria 1 Torino Italy Max-Planck-Institut für Physik Föhringer Ring 6 München Germany Università degli Studi di Torino Dipartimento di Fisica Via P. Giuria 1 Torino Italy University of Tokyo Institute for Cosmic Ray Research 5-1-5 Kashiwa-no-ha Chiba Kashiwa277-8582 Japan University of Lodz Faculty of Physics and Applied Informatics ul. Pomorska 149-153 Lodz Poland Hiroshima University Physics Program Graduate School of Advanced Science and Engineering Hiroshima739-8526 Japan Department of Physics Tokai University Japan ETH Zürich Switzerland Instituto de Astrofísica de Canarias Departamento de Astrofísica Universidad de La Laguna Spain Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Spain Instituto de Astrofísica de Andalucía-CSIC Spain EMFTEL department IPARCOS Universidad Complutense de Madrid Spain Italy INFN Sezione di Trieste Università degli Studi di Udine Italy Italy INAF - Osservatorio Astronomico di Roma Italy INFN Sezione di Napoli Italy INFN Sezione di Padova Università degli Studi di Padova Italy The Barcelona Institute of Science and Technology Spain LAPP Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS-IN2P3 Annecy France Department of Physics TU Dortmund University Germany Croatia Universität Hamburg Institut für Experimentalphysik Germany Graduate School of Science University of Tokyo Japan Universidad del Azuay Ecuador INAF - Osservatorio di Astrofisica e Scienza dello spazio di Bologna Italy Centro Brasileiro de Pesquisas Físicas Brazil CIEMAT Spain INFN Sezione di Bari Politecnico di Bari Italy INAF - Osservatorio Astronomico di Brera Italy University of Geneva Département de physique nucléaire et corpusculaire Switzerland INFN Sezione di Catania Italy Departament de Física CERES-IEEC Universitat Autónoma de Barcelona Spain Italy Università di Pisa INFN Pisa Italy Aix Marseille Univ CNRS IN2P3 CPPM France INFN Sezione di Bari

The prototype Large-Sized Telescope (LST-1) of the Cherenkov Telescope Array Observatory (CTAO) is in commissioning phase at the Observatorio del Roque de Los Muchachos at 2200 m a.s.l. in La Palma (Canary Islands, Spain). LST-1 is a 23-m diameter telescope and is the first of four that will compose the LST part of the CTAO Northern array. The LST subarray is optimized to provide the best sensitivity for gamma rays in the 20 GeV - 200 GeV energy range. The MAGIC telescopes, which are located approximately 100 m from the LST-1, is operating as a two 17-m telescope stereoscopic system for more than 14 years. LST-1 and MAGIC routinely perform joint observations of gamma-ray sources to exploit the potential of the three-telescope system. This contribution describes the analysis pipeline and evaluates the performance of the system using Monte Carlo simulations and data on the Crab Nebula. The sensitivity achieved during joint observations with MAGIC and LST-1 is about 30% higher than that of MAGIC alone. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Stereo image processing

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Inhaled D-Limonene minimizes acute lung injury and reduces oxidative stress induced by smoke in rats

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Phytomedicine Plus 2022年第3期2卷 100308-100308页

作者： Santana, Hericalizandra Santa Rosa de Carvalho, Fernanda Oliveira Menezes dos Santos, Danillo da Silva, Eric Aian Pereira Silva, Érika Ramos Shanmugam, Saravanan Heimfarth, Luana Nunes, Paula Santos de Oliveira e Silva, Ana Mara Araújo, Adriano Antunes de Souza de Albuquerque, Ricardo Luiz Cavalcanti Viana dos Santos, Márcio Roberto Health Sciences Graduate Program Federal University of Sergipe (UFS) Cláudio Batista St s/n Aracaju-SE Sanatório Brazil Biotechnology Graduate Program - RENORBIO Federal University of Sergipe (UFS) Marechal Rondom Avenue s/n SE São Cristóvão Brazil Department of Physiotherapy Federal University of Sergipe (UFS) Gov. Marcelo Deda Avenue 300 SE Lagarto Brazil Department of Physiology Federal University of Sergipe (UFS) Marechal Rondom Avenue s/n SE São Cristóvão Brazil Department of Morphology Federal University of Sergipe (UFS) Marechal Rondom Avenue s/n SE São Cristóvão Brazil Department of Nutrition Federal University of Sergipe (UFS) Marechal Rondom Avenue s/n SE São Cristóvão Brazil Department of Pharmacy Federal University of Sergipe (UFS) Marechal Rondom Avenue s/n SE São Cristóvão Brazil Sergipe Institute of Technology and Research Tiradentes University (UNIT) Murilo Dantas Avenue 300 Farolândia SE Aracaju Brazil

Background: Despite some advances in the discovery of novel therapies, smoke inhalation injury remains a difficult to treat critical health issue due to its physiopathological complexity. Natural products, such as D-limonene (LIM), are becoming an important potential source of new treatments in many health problems. LIM has been shown to have antioxidant, anti-inflammatory and protective effects in respect of several diseases, including respiratory conditions. Objective: The aim of this study was to evaluate the effects of inhaled LIM on acute smoke-induced lung injury in rats. Methods: Thirty minutes after smoke inhalation, adult male Wistar rats were treated with vehicle or LIM (0.01 mg/kg) for 30 min. Blood samples, and the liver, lungs, and trachea were collected for analysis. Results: The results showed that LIM minimized the injuries, reducing oxidative and inflammatory damage by improving catalase (CAT) (p < 0.05), and superoxide dismutase (SOD) activities (trachea: p < 0.01;lung: p < 0.05) and reducing interleukin-1 beta (IL-1β) level (p < 0.01) caused by smoke inhalation. LIM was also able to ameliorate damage in both trachea and lung tissues. Conclusions: The results indicate that LIM has a beneficial effect on lung injury, mainly by reducing oxidative stress, anti-inflammatory response and tissue damage. © 2022 The Author(s)

关键词： D-limonene Lung injury Monoterpene Oxidative damage Smoke

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Actual Evapotranspiration for Sugarcane Based on Bowen Ratio-Energy Balance and Soil Water Balance Models with Optimized Crop Coefficients.

Research Square

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Research Square 2021年

作者： da Costa Faria Martins, Suelen dos Santos, Marcos Alex Lyra, Gustavo Bastos de Souza, José Leonaldo Lyra, Guilherme Bastos Teodoro, Iêdo Ferreira, Fábio Freitas Ferreira, Ricardo Araújo dos Santos Almeida, Alexsandro Claudio de Souza, Renan Cantalice Graduate Program in Agricultural and Environmental Engineering Department of Agricultural and Environmental Engineering Institute of Technology Federal Rural University of Rio de Janeiro Seropédica Rio de Janeiro23.890-000 Brazil Agricultural Science Center Federal University of Alagoas AL Rio Largo57100-000 Brazil Department of Environmental Sciences Forest Institute Federal Rural University of Rio de Janeiro Seropédica Rio de Janeiro23.890-000 Brazil Department of Natural Sciences Institute of Humanity and Health Fluminense Federal University Rio das Ostras RJ 28895-532 Brazil

Evapotranspiration is an important parameter to evaluate soil water deficit and water use efficiency, especially at places with irregularly distributed precipitation. The aim of this study was to assess the daily actual evapotranspiration (ETa) estimated by the Thornthwaite and Mather soil water balance method adapted for crops (ThM) and by the dual Kc approach with the crop coefficients optimized from inversing modeling and by the adjustment procedure suggested in FAO-56. The models comparison and optimization were performed with actual evapotranspiration determined by the Bowen ratio – energy balance method (ETβ) for sugarcane at full canopy closure grown in Alagoas State, Northeastern Brazil. The objective function of the inverse problem was defined in terms of ETβ and ETa estimated by the ThM and dual Kc method by optimizing single crop coefficient (Kc) and the basal coefficient Kcb, respectively. Both optimized Kc and Kcb were lower than the adjusted Kc FAO56, with optimized Kc only 3% less than the Kc obtained experimentally. ETa estimated by ThM and dual Kc models with optimized crop coefficients (Kc = 1.05 or Kcb = 1.00) had similar high precision (r2 > 0.79) and accuracy (dm > 0.93 and RMSE -1), whereas using the coefficients derived from FAO 56 overestimated ETa in both models. © 2021, CC BY.

关键词： Evapotranspiration

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Emotion recognition in doctor-patient interactions from real-world clinical video database: Initial development of artificial empathy

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Computer Methods and programs in Biomedicine 2023年 233卷 107480-107480页

作者： Huang, Chih-Wei Wu, Bethany C.Y. Nguyen, Phung Anh Wang, Hsiao-Han Kao, Chih-Chung Lee, Pei-Chen Rahmanti, Annisa Ristya Hsu, Jason C. Yang, Hsuan-Chia Li, Yu-Chuan Jack Taipei Medical University Taipei Taiwan Taipei Medical University Ringgold standard institution - Center for Simulation in Medical Education Taipei 116 Taiwan National Taiwan University Children and Family Research Center Sponsored by CTBC Charity Foundation Taipei Taiwan Clinical Data Center Office of Data Science Taipei Medical University Taipei Taiwan Clinical Big Data Research Center Taipei Medical University Hospital Taipei Taiwan Graduate Institute of Biomedical Informatics College of Medical Science and Technology Taipei Medical University TMU Da'an Campus 15 F No. 172-1 Kee lung Road Section 2 Da-an District Taipei Taiwan Research Center of Big Data and Meta-analysis Wanfang Hospital Taipei Medical University Taipei Taiwan Department of Dermatology Wanfang Hospital Taipei Medical University Taiwan Department of Dermatology School of Medicine College of Medicine Taipei Medical University Taipei Taiwan Delta Research Center Taipei Taiwan Department of Health Policy and Management Faculty of Medicine Public Health and Nursing Universitas Gadjah Mada Yogyakarta Indonesia International PhD Program in Biotech and Healthcare Management College of Management Taipei Medical University Taipei Taiwan Research Center of Data Science on Healthcare Industry College of Management Taipei Medical University Taipei Taiwan

Background and objective: The promising use of artificial intelligence (AI) to emulate human empathy may help a physician engage with a more empathic doctor-patient relationship. This study demonstrates the application of artificial empathy based on facial emotion recognition to evaluate doctor-patient relationships in clinical practice. Methods: A prospective study used recorded video data of doctor-patient clinical encounters in dermatology outpatient clinics, Taipei Municipal Wanfang Hospital, and Taipei Medical University Hospital collected from March to December 2019. Two cameras recorded the facial expressions of four doctors and 348 adult patients during regular clinical practice. Facial emotion recognition was used to analyze the basic emotions of doctors and patients with a temporal resolution of 1 second. In addition, a physician-patient satisfaction questionnaire was administered after each clinical session, and two standard patients gave impartial feedback to avoid bias. Results: Data from 326 clinical session videos showed that (1) Doctors expressed more emotions than patients (t [326] > = 2.998, p © 2023

关键词： Emotion Recognition

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