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Association of serum NO_x level with clustering of metabolic syndrome components in middle-aged and elderly general populations in Japan

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Environmental Health and Preventive Medicine 2008年第1期13卷 36-42页

作者： Ueyama, Jun Kondo, Takaaki Imai, Ryota Kimata, Akiko Yamamoto, Kanami Suzuki, Koji Inoue, Takashi Ito, Yoshinori Miyamoto, Ken-Ichi Hasegawa, Takaaki Hamajima, Nobuyuki Program in Radiological and Medical Laboratory Science Nagoya University Graduate School of Medicine Higashi-ku Nagoya 461-8673 1-1-20 Daikominami Japan Department of Medical Informatics Graduate School of Medical Science Kanazawa University Kanazawa Japan Department of Public Health Fujita Health University School of Health Sciences Aichi Japan Department of Pharmacy and Pharmacokinetics Aichi Medical University School of Medicine Aichi-gun Aichi Nagakute-cho Japan Department of Preventive Medicine/Biostatistics and Medical Decision Making Nagoya University Graduate School of Medicine Nagoya Japan

Objectives: The aim of this study was to determine whether the serum nitrite plus nitrate (NOx) level correlates with biomarkers that are known components of the metabolic syndrome (MetS). Methods: Serum NOx levels we... 详细信息

Objectives: The aim of this study was to determine whether the serum nitrite plus nitrate (NO_x) level correlates with biomarkers that are known components of the metabolic syndrome (MetS). Methods: Serum NO_x levels were measured using a commercial kit in 608 Japanese men and women between the ages of 39 and 85 years. Multivariate adjustments for age, smoking status, alcohol consumption and exercise were made in the analysis of covariance (ANCOVA). The components of the metabolic syndrome were defined based on the following criteria: body mass index (BMI) ≥25.0 kg/m², glycated hemoglobin (HbA1c) ≥5.6%, systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg, high-density lipoprotein-cholesterol (HDL-C) ≤1.03 mmol/l for men and ≤1.29 mmol/l for women and triglyceride ≥1.69 mmol/l. Results: The logarithmically transformed age-adjusted serum NO _x (lnNO_x) value was significantly higher in the low HDL-C group (1.76 ± 0.05 μmol/l;p < 0.05) than MetS component groups (1.65 ± 0.01 μmol/l) in men, but no difference was found in women. The means of serum lnNO_x after multivariate adjustment were 1.64, 1.65, 1.64, 1.66, and 1.81 μmol/l for 0, 1, 2, 3, and 4-5 MetS components for all subjects, respectively. The results of ANCOVA confirmed that the serum lnNO _x level was significantly correlated with the clustering of MetS components in both men and women (p < 0.0001 for trend). Conclusion: Our results suggest that an increase in the clustering of MetS components was associated with the increase in serum NO levels in our general population. © 2008 Japanese Society for Hygiene.

关键词： Analysis of covariance Cyclic guanosine 3′5′-Monophosphate (cGMP) Metabolic syndrome Nitric oxide

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An interoperability approach based on asynchronous replication among distributed internet databases

An interoperability approach based on asynchronous replicati...

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IEEE Symposium on Computers and Communications (ISCC)

作者： Douglas D. J. de Macedo Hilton W. G. Perantunes Luiz F. J. Maia Eros Comunello Aldo von Wangenheim M.A.R. Dantas Department of Informatics and Statistics (INE) Federal University of Santa Catarina Florianopolis Brazil Post-Graduate Program Knowledge Engineering and Management (PPGEG) Federal University of Santa Catarina Florianopolis Brazil Department of Informatics and Statistics (INE) Florianopolis Brazil Federal University of Santa Catarina (UFSC) Post-Graduate Program in Knowledge Engineering and Management (PPGEGC) Florianopolis Brazil 88040-900

Nowadays, there is a growing interest in telemedicine in Brazil, because the country is the fifth largest country in the world and there is a huge gap between the population size and the number of available doctors. Institutions and the government are considering solutions for the integration and availability of data produced by several different systems. In this paper we present a contribution that is characterized by an asynchronous replication strategy between distributed medical databases. The contribution, named PGR, is an enhancement to the PostgreSQL database software that introduces lightweight asynchronous operations. In addition, we have implemented a multi-master engine with partial replication and hybrid fragmentation in order to allow interoperability between different telemedicine systems. Our early results indicate that the model and its implementation have reached a successful level in terms of performance and interoperability.

关键词： Databases Proposals Distributed databases Medical services Software Monitoring Biomedical imaging

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WebAnima: A Web-Based Embodied Conversational Assistant to Interface Users with Multi-Agent-Based CSCW Applications

WebAnima: A Web-Based Embodied Conversational Assistant to I...

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12th International Conference on Computer Supported Cooperative Work in Design (CSCWD 2008), vol.1

作者： Emerson Cabrera Paraiso Yuri Campbell Cesar A. Tacla Post-Graduate Program on Informatics Pontifical Catholic University of Paraná Curitiba Parana Brazil Universidade Tecnológica Federal do Paraná Curitiba Parana Brazil

ISBN: (纸本)9781424416509

WebAnima is an interface agent specially designed to assist team members of a CSCW application during their daily work based on computers. In WebAnima, the intelligent behavior is guaranteed thanks to a conversational interface and ontologies that support semantic interpretation. We believe that embodied conversational assistants will improve the quality of assistance and increase collaboration between project members. In this paper, we present the embodied conversational assistant and its insertion into a multi-agent system designed for research and development projects. We describe the design of the agent, highlighting the role of ontologies for semantic interpretation and the dynamic behavior of the embodied animated agent.

关键词： Personal Assistants Animated Agents CSCW Knowledge Management Ontology

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Using a novel approach to cluster analysis to gain new valuable insights into software-project risk management

Using a novel approach to cluster analysis to gain new valua...

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IEEE/IFIP International Workshop on Business-Driven IT Management (BDIM)

作者： Antonio Juarez Alencar Leoncio Teixeira Cruz Eber Assis Schmitz Armando Leite Ferreira Graduate Program in Informatics Institute of Mathematics and Electronic Computer Center Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil The COPPEAD School of Business Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil

ISBN: (纸本)9781424421916

This work presents a method that provides organizations and their project managers with a better understanding of the implications of the risks that software projects are subjected to. The method, which is based upon a novel approach to cluster analysis, generates a set of business rules indicating how risk factors may influence project performance. These rules are easy to read and understand, making it easier for managers to identify what needs to be done and when it needs to be done, before the worst happens.

关键词： Risk analysis Risk management Project management Performance analysis informatics Mathematics Information technology Europe Financial management Productivity

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A quantitative risk model-building method for offshoring IT applications

A quantitative risk model-building method for offshoring IT ...

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IEEE/IFIP International Workshop on Business-Driven IT Management (BDIM)

作者： Carlos Henrique Faria Alves Antonio Juarez Alencar Eber Assis Schmitz Armando Leite Ferreira Graduate Program in Informatics Institute of Mathematics and Electronic Computer Center Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil The COPPEAD School of Business Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil

ISBN: (纸本)9781424421916

Off shoring IT services has become a key factor in building successful business strategies, allowing companies to better position themselves in today's highly competitive markets. Nevertheless, off shoring brings to the table a brand new set of possibilities and risks regarding its management and execution. This article presents a method for the elaboration of a quantitative risk model for off shoring IT applications, which, in turn, increases the likelihood of being successful in such initiatives.

关键词： Companies Risk management Switches Costs Outsourcing Mathematical model Application software informatics Mathematics Consumer electronics

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On Self-Organizing Feature Map (SOFM) Formation by Direct Optimization Through a Genetic Algorithm

On Self-Organizing Feature Map (SOFM) Formation by Direct Op...

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International Conference on Hybrid Intelligent Systems (HIS)

作者： José Everardo B. Maia Guilherme A. Barreto André L.V. Coelho Department of Teleinformatics Engineering Federal University of Ceará Fortaleza Ceara Brazil Department of Statistics and Computing State Univ. of Ceara Fortaleza Ceara Brazil Department of Statistics and Computing State University of Ceará Fortaleza Ceara Brazil Department of Teleinformatics Engineering Federal Univ. of Ceara Fortaleza Ceara Brazil Graduate Program in Applied Informatics University of Fortaleza Fortaleza Ceara Brazil

This paper examines the formation of self-organizing feature maps (SOFM) by the direct optimization of a cost function through a genetic algorithm (GA). The resulting SOFM is expected to produce simultaneously a topologically correct mapping between input and output spaces and a low quantization error. The proposed approach adopts a cost (fitness) function which is a weighted combination of indices that measure these two aspects of the map quality, specifically, the quantization error and the Pearson correlation coefficient between the corresponding distances in input and output spaces. The resulting maps are compared with those generated by the Kohonen's self-organizing map (SOM) algorithm in terms of the quantization error (QE), the weighted topological error (WTE) and the Pearson correlation coefficient (PCC) indices. The experiments show the proposed approach produces better values of the quality indices as well as is more robust to outliers.

关键词： Gallium Neurons Arrays Genetic algorithms Indexes Optimization Genetics

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A collaborative approach to requirements elicitation

A collaborative approach to requirements elicitation

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11th International Conference on Computer Supported Cooperative Work in Design, CSCWD 2007

作者： Laporti, Viviane Borges, Marcos R. S. Braganholo, Vanessa P. Graduate Program in Informatics Federal University of Rio de Janeiro Brazil

ISBN: (纸本)1424409632

The requirements elicitation of a system is a complex task. The different viewpoints and the need for negotiation make this stage of the software development process risky and susceptible to failures. The traditional elicitation approach based on interviews and questionnaires do not help. This paper proposes an approach founded on collective knowledge to progressively build the system requirements from a narrative of use stories to the definition of use cases. The proposed solution consists of a knowledge model based on stories about the system, a collective construction method, and a tool to support interaction. ©2007 IEEE.

关键词： Surveys

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Recalling resilient actions during emergency response

Recalling resilient actions during emergency response

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1st International Workshop on Mobile Information Technology for Emergency Response, Mobile Response 2007

作者： Dos Reis, Marcelo Índio Borges, Marcos R. S. Gomes, José Orlando Graduate Program in Informatics - IM and NCE Federal University of Rio de Janeiro Brazil

ISBN: (纸本)9783540756675

The analysis of emergency response actions usually concentrates on failures as a means to improve future procedures and emergency plans. In this paper we adopt a resilience approach that focuses on the analysis of successful actions. We use group storytelling to recall the actions performed by emergency teams during an incident. A method aimed at recognizing resilient actions is proposed and its application is illustrated in a real case. © Springer-Verlag Berlin Heidelberg 2007.

关键词： Disaster prevention

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Capturing context about group design processes

Capturing context about group design processes

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11th International Conference on Computer Supported Cooperative Work in Design, CSCWD 2007

作者： Nunes, Vanessa Tavares Santoro, Flavia Maria Borges, Marcos R. S. Graduate Program in Informatics UFRJ Brazil Departamento de Informatica Aplicada UNIRIO Brazil

ISBN: (纸本)1424409632

Knowledge Management has become a prominent subject for organizations, but often characterization and treatment of the information that flows in a well-defined design work process are muddled. We argue that context is the fundamental information resource for better understanding and carrying on activities and interactions. We propose an environment to support the cycle of creating and dealing with information about activities and interaction, focusing on their context. The goal of this paper is to discuss and specify mechanisms that can be used to collect context information within this environment. ©2007 IEEE.

关键词： Knowledge management

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An observation model for the collaborative analysis of real workplaces

An observation model for the collaborative analysis of real ...

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11th International Conference on Computer Supported Cooperative Work in Design, CSCWD 2007

作者： Machado, Renata Guanaes Borges, Marcos R. S. Guerlain, Stephanie Gomes, Jose Orlando Graduate Program in Informatics Federal University of Rio de Janeiro Brazil Systems and Information Engineering Dept. University of Virginia Charlottesville VA United States

ISBN: (纸本)1424409632

Many approaches to work analysis have been proposed so as to enhance the requirements elicitation for systems design. However, systems delivered at dynamic, complex and socio-technical workplaces, have stillfailed at satisfying the needs of users successfully, mainly because they are unable to support activities entirely, especially those related with cognition and collaboration. This paper describes the Observation Conceptual Model, as a complementary approach, to elicit high-quality requirements through systematic field studies about organizations. We also include some ideas for the elaboration of a collaborative system that supports the conceptual model. ©2007 IEEE.

关键词： Groupware

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