We developed a new tissue-engineered bone graft model composed of bovine bone marrow stromal cells (BMSCs), and beta tricalcium phosphate (beta TCP) porous beads. Such cell-bead sheets were prepared by means of cultiv...
详细信息
The specific sensing of antigen-antibody interaction was examined by using a PEGylated sensor. For the surface modification, acetal-PEG-SH was prepared and by using acetal-PEG-SH, PEG brush was constructed on the gold...
详细信息
ISBN:
(纸本)1877040193
The specific sensing of antigen-antibody interaction was examined by using a PEGylated sensor. For the surface modification, acetal-PEG-SH was prepared and by using acetal-PEG-SH, PEG brush was constructed on the gold sensor chip surface. Modification of antibody was carried out by conjugation of SH group in Fab' to the maleimide group at the distal end of PEG chains on the surface. The result shows that the suitable modification of antibody on the PEG brush surface is very important to obtain high sensing character.
The improved synthesis of poly(α,β-malic acid) (PMA) by direct polycondensation with high yield and increased molecular weight, was analyzed. To determine the chemical structure of the products, the 1NMR and 13C NMR...
详细信息
ISBN:
(纸本)1877040193
The improved synthesis of poly(α,β-malic acid) (PMA) by direct polycondensation with high yield and increased molecular weight, was analyzed. To determine the chemical structure of the products, the 1NMR and 13C NMR spectra were also measured by an IR spectrometer. It was observed that the polymerization reaction proceeded faster at 130°C, but the molecular weight increased to about 3,500. The results show that the equilibrium of polymerization may shift toward the depolymerization at a higher reaction temperature, exhibiting a decrease in maximum molecular weight of α,β-PMA with an increase in the reaction temperature.
Three-dimensional biodegradable porous scaffolds play an important role in tissue engineering. We created double-layered porous scaffolds composed of synthetic biodegradable polymers by combining freeze-drying and por...
详细信息
The application of hybrid mesh as a three-dimensional scaffold for the culture of canine articular chondrocytes and bone marrow stromal cell to generate osteochondral implants was discussed. The hybrid mesh was prepar...
详细信息
ISBN:
(纸本)1877040193
The application of hybrid mesh as a three-dimensional scaffold for the culture of canine articular chondrocytes and bone marrow stromal cell to generate osteochondral implants was discussed. The hybrid mesh was prepared by forming collagen microsponges in the openings of poly(lactic-co-glycolic acid) (PLGA) knitted mesh. It was found that both the chondrocytes and the stromal cells stick onto the hybrid scaffold and proliferated filling the spaces in the scaffold. The result show the possibility of construction of osteochondral implants by culturing chondrocytes and bone marrow stromal cells in the PLGA-collagen hybrid mesh.
The use of a hybrid mesh scaffold of biodegradable synthetic polymer PLGA and collagen for cartilage tissue engineering was discussed. The hybrid mesh was prepared by forming collagen microsponges in the opening of a ...
详细信息
ISBN:
(纸本)1877040193
The use of a hybrid mesh scaffold of biodegradable synthetic polymer PLGA and collagen for cartilage tissue engineering was discussed. The hybrid mesh was prepared by forming collagen microsponges in the opening of a PLGA knitted mesh made polylactine 910. The PLGA mesh and PLGA-collagen hybrid mesh structure were observed by scanning electron microscopy (SEM). Articular cartilage implant was reconstructed when bovine chondrocytes were cultured in the hybrid mesh. The bright safranin-O-positive stain indicated that glycosaminoglycans (GAG) were abundant and homogeneously distributed throughout the implants.
Canine chondrocytes isolated from articular cartilage were cultured in a PLGA-collagen hybrid mesh in DMEM containing 10% FBS in vitro for 10 days, and subsequently implanted subcutaneously in the dorsum of nude mouse...
详细信息
The stable dispersion of quantum dot nanoparticles (QD) in aqueous solution using polymers containing poly(ethylene glycol) (PEG) segment was investigated. It was found that using PEG/poly(2-N,N-dimethylaminoethyl met...
详细信息
ISBN:
(纸本)1877040193
The stable dispersion of quantum dot nanoparticles (QD) in aqueous solution using polymers containing poly(ethylene glycol) (PEG) segment was investigated. It was found that using PEG/poly(2-N,N-dimethylaminoethyl methacrylate) (PEG-b-PAMA) enables stabilization of QD in aqueous phase. The photochemical characteristics of the PEG-modified QD were found to be almost same as unmodified QD. It was observed that as he PEG/PAMA block copolymer-modified QDs possess PEG tethered chains on the surface, it is highly dispersion stable in aqueous media and also showed non-fouling character.
Experimental results regarding Li2O-ZrO2-SiO 2 (LZS) sintered glass ceramic materials obtained by extrusion of glass powders with an added inorganic material as binder, are presented. Each of the composition were char...
详细信息
Experimental results regarding Li2O-ZrO2-SiO 2 (LZS) sintered glass ceramic materials obtained by extrusion of glass powders with an added inorganic material as binder, are presented. Each of the composition were characterized by chemical analysis, laser scattering particle-size analysis, differential thermal analysis (DTA), Xray diffractometry (XRD), and thermal expansion. It was observed that after a sintering process at near by 750°C, crystallization takes place as soon as the process gets over. Once heated, the the glass powder compacts crystallize into zircon and quartz and then to lithium disilicate.
Bone marrow-derived mesenchymal stem cells (BMDMSCs) possess pluripotent differentiation potential including differentiation into osteoblasts, chondrocytes, adipocytes, and muscle cells. Using tissue engineering techn...
详细信息
暂无评论